Abstract: A disease or condition, such as cancer or an infectious disease, can be treated in a patient by administering a CTLA-4 antibody in an escalating dosage regimen until a partial or complete response is elicited in the patient or a pre-determined maximum dosage is reached.

Abstract: A continuously variable transmission (CVT) having a main shaft configured to support and position various components of the CVT. Shift cam discs cooperate with ball-leg assemblies to shift the transmission ration of the CVT. Load cam discs, a torsion disc, rolling elements, and a hub cap shell are configured to generate axial force, transmit torque, and manage reaction forces. In one embodiment, a splined input shaft and a torsion disc having a splined bore cooperate to input torque into the variator of the CVT. Among other things, various ball axles, axle-ball combinations, and reaction force grounding configurations are disclosed. In one embodiment, a CVT having axial force generation means at both the input and output elements is disclosed.

Abstract: The present invention provides strategies for making high quality CIGS photoabsorbing compositions from sputtered precursor film(s). The precursors are converted into CIGS photoabsorbing material via a chalcogenizing treatment (also referred to as “post-chalcogenization,” including, e.g., “post-selenization” when Se is used and/or “post-sulfurization” when S is used) using techniques that allow the post-chalcogenizing treatment to occur under atypically low pressure conditions. Consequently, the strategies of the invention are readily incorporated into batch processes or continuous processes such as roll-to-roll process occurring under vacuum. The present invention is useful at lab, pilot plant, and industrial scales.

Abstract: Inventive embodiments are directed to components, subassemblies, systems, and/or methods for continuously variable transmissions (CVT). In one embodiment, a main axle (112) is adapted to receive a carrier assembly (101, 400, 600, 800) to facilitate the support of components in a CVT (100). In another embodiment, a carrier includes a stator support member (206, 304, 402, 502, 602, 802) and a stator interfacial member (208, 504). In some embodiments, the stator interfacial member is configured to interact with planet subassemblies of a CVT. Various inventive planet subassemblies (108, 406, 806) and idler assemblies (109, 700) can be used to facilitate shifting the ratio of a CVT. In some embodiments, the planet subassemblies include legs (244, 2444, 424, 810) configured to have a sliding interface with a carrier assembly.

Abstract: A continuously variable transmission (CVT) having a number of tiltable ball-leg assemblies configured angularly about a longitudinal axis. Each ball-leg assembly is in contact with, and guided through a tilting motion by an axially translating shift cam having a convex shape. The convex shape of the shift cam can have a profile defined by a set of parametric equations. In one embodiment, the profile of the shift cam vary according to the location of the contact point between an idler and the ball-leg assembly as well as the amount of relative axial motion between the ball-leg assembly and the idler. In some embodiments, the profile of the shift cam can be configured to control the axial translation of the idler relative to the change in tilt angle of the ball-leg assembly. In other embodiments, a roll-slide factor can be used to characterize the axial translation of the idler relative to the tilt angle of the ball-leg assembly.

Abstract: A continuously variable transmission (CVT) having a main shaft configured to support and position various components of the CVT. Shift cam discs cooperate with ball-leg assemblies to shift the transmission ration of the CVT. Load cam discs, a torsion disc, rolling elements, and a hub cap shell are configured to generate axial force, transmit torque, and manage reaction forces. In one embodiment, a splined input shaft and a torsion disc having a splined bore cooperate to input torque into the variator of the CVT. Among other things, various ball axles, axle-ball combinations, and reaction force grounding configurations are disclosed. In one embodiment, a CVT having axial force generation means at both the input and output elements is disclosed.

Abstract: A continuously variable transmission (CVT) having a main shaft configured to support and position various components of the CVT. Shift cam discs cooperate with ball-leg assemblies to shift the transmission ration of the CVT. Load cam discs, a torsion disc, rolling elements, and a hub cap shell are configured to generate axial force, transmit torque, and manage reaction forces. In one embodiment, a splined input shaft and a torsion disc having a splined bore cooperate to input torque into the variator of the CVT. Among other things, various ball axles, axle-ball combinations, and reaction force grounding configurations are disclosed. In one embodiment, a CVT having axial force generation means at both the input and output elements is disclosed.

Abstract: A load control device for controlling the power delivered from an AC power source to an electrical load is operable to be converted from being configured as an electronic switch to being configured as a dimmer switch after installation. The load control device comprises a dimmer bezel having a control actuator and an intensity adjustment actuator and a detachable switch bezel adapted to be attached to the dimmer bezel. The detachable switch bezel has an opening through which the control actuator may be actuated, and is adapted to cover the intensity adjustment actuator when the detachable switch bezel is attached to the dimmer bezel. The load control device is operable to change from a switch mode of operation to a dimmer mode of operation after the detachable switch bezel is removed from the dimmer bezel.

Abstract: Inventive embodiments are directed to components, subassemblies, systems, and/or methods for continuously variable transmissions (CVT). In one embodiment, a main axle is adapted to receive a shift rod that cooperates with a shift rod nut to actuate a ratio change in a CVT. In another embodiment, an axial force generating mechanism can include a torsion spring, a traction ring adapted to receive the torsion spring, and a roller cage retainer configured to cooperate with the traction ring to house the torsion spring. Various inventive idler-and-shift-cam assemblies can be used to facilitate shifting the ratio of a CVT. Embodiments of a hub shell and a hub cover are adapted to house components of a CVT and, in some embodiments, to cooperate with other components of the CVT to support operation and/or functionality of the CVT. Among other things, shift control interfaces and braking features for a CVT are disclosed.

Abstract: Traction planets and traction rings can be operationally coupled to a planetary gearset to provide a continuously variable transmission (CVT). The CVT can be used in a bicycle. In one embodiment, the CVT is mounted on the frame of the bicycle at a location forward of the rear wheel hub of the bicycle. In one embodiment, the CVT is mounted on and supported by members of the bicycle frame such that the CVT is coaxial with the crankshaft of the bicycle. The crankshaft is configured to drive elements of the planetary gearset, which are configured to operationally drive the traction rings and the traction planets. Inventive component and subassemblies for such a CVT are disclosed. A shifting mechanism includes a plurality of pivot arms arranged to pivot about the centers of the traction planets as a shift pin hub moves axially.

Abstract: A continuously variable transmission (CVT) having a main shaft configured to support and position various components of the CVT. Shift cam discs cooperate with ball-leg assemblies to shift the transmission ration of the CVT. Load cam discs, a torsion disc, rolling elements, and a hub cap shell are configured to generate axial force, transmit torque, and manage reaction forces. In one embodiment, a splined input shaft and a torsion disc having a splined bore cooperate to input torque into the variator of the CVT. Among other things, various ball axles, axle-ball combinations, and reaction force grounding configurations are disclosed. In one embodiment, a CVT having axial force generation means at both the input and output elements is disclosed.

Abstract: A multi junction photovoltaic device is disclosed. In certain examples, the device includes an upper photovoltaic cell comprising a first plurality of layers of films, including a first active layer of a chalcogenide having a first lattice constant and first energy band gap, and a lower photovoltaic cell disposed below the upper photovoltaic cell and adapted to receive photon radiation passing through the upper photovoltaic cell, and comprising a second plurality of layers of films, including an active second layer of a IB-IIIA-chalcogenide having a second lattice constant and a second energy band gap. The first lattice constant differs from the second lattice constant by no more than about 10%. The first energy band gap can be greater than the second energy band gap by at least about 0.5 eV, or 0.6 eV, or 0.7 eV.

Abstract: An apparatus for attaching a tag to an object. The apparatus may include a body. The apparatus may also include an attachment arm, the attachment arm having a locked position and an unlocked position, and the attachment arm lockably closing to form a first closed loop with the body when the attachment arm is in the locked position. The apparatus may also include a tag loop mechanically coupled to the body. The apparatus may also include a detent arm mechanically engaged with the attachment arm in the locked position of the attachment arm, the detent arm configured so that an application of a force to the detent arm simultaneously unlocks the attachment arm and opens the tag loop.

Abstract: Inventive embodiments are directed to components, subassemblies, systems, and/or methods for continuously variable transmissions (CVT). In one embodiment, a main axle is adapted to receive a shift rod that cooperates with a shift rod nut to actuate a ratio change in a CVT. In another embodiment, an axial force generating mechanism can include a torsion spring, a traction ring adapted to receive the torsion spring, and a roller cage retainer configured to cooperate with the traction ring to house the torsion spring. Various inventive idler-and-shift-cam assemblies can be used to facilitate shifting the ratio of a CVT. Embodiments of a hub shell and a hub cover are adapted to house components of a CVT and, in some embodiments, to cooperate with other components of the CVT to support operation and/or functionality of the CVT. Among other things, shift control interfaces and braking features for a CVT are disclosed.

Abstract: Inventive embodiments are directed to components, subassemblies, systems, and/or methods for continuously variable transmissions (CVT). In one embodiment, a control system is adapted to facilitate a change in the ratio of a CVT. In another embodiment, a control system includes a stator plate configured to have a plurality of radially offset slots. Various inventive traction planet assemblies and stator plates can be used to facilitate shifting the ratio of a CVT. In some embodiments, the traction planet assemblies include planet axles configured to cooperate with the stator plate. In one embodiment, the stator plate is configured to rotate and apply a skew condition to each of the planet axles. In some embodiments, a stator driver is operably coupled to the stator plate. Embodiments of a traction sun are adapted to cooperate with other components of the CVT to support operation and/or functionality of the CVT. Among other things, shift control interfaces for a CVT are disclosed.

Abstract: A rope climbing apparatus (15) comprising a frame (16), a seat (18) supported by the frame and adapted to move relative to the frame from a first position (19) to an elevated second position (20), a lower pulley assembly (21) connected to the seat, an upper pulley assembly (22) connected to the frame, a rope (23) extending between the lower pulley assembly and the upper pulley assembly and having a rope climbing portion (24) graspable by a user (25) when the user is seated on the seat, and the rope, the seat, the lower pulley assembly and the upper pulley assembly configured and arranged such that a downward force (26) on the rope climbing portion of the rope causes an upward force (28) on the seat. The downward force on the rope climbing portion may result in an upward force on the seat at a mechanical advantage provided by the lower pulley assembly and the upper pulley assembly, and the mechanical advantage may be four.

Abstract: A continuously variable transmission (CVT) having a torsion disc for a CVT. The torsion disc includes a splined bore about its central axis, an annular recess formed in the disc for receiving the race of a bearing, and a raised surface for supporting a torsion spring. In one embodiment, the torsion disc includes a number of holes for receiving dowels that support a torsion spring. Load cam discs, a torsion disc, rolling elements, and a hub cap shell are configured to generate axial force, transmit torque, and manage reaction forces. In one embodiment, a splined input shaft and a torsion disc having a splined bore cooperate to input torque into the variator of the CVT. Among other things, various ball axles, axle-ball combinations, and reaction force grounding configurations are disclosed. In one embodiment, a CVT having axial force generation means at both the input and output elements is disclosed.

Abstract: A continuously variable transmission (CVT) having a main shaft configured to support and position various components of the CVT. Shift cam discs cooperate with ball-leg assemblies to shift the transmission ration of the CVT. Load cam discs, a torsion disc, rolling elements, and a hub cap shell are configured to generate axial force, transmit torque, and manage reaction forces. In one embodiment, a splined input shaft and a torsion disc having a splined bore cooperate to input torque into the variator of the CVT. Among other things, various ball axles, axle-ball combinations, and reaction force grounding configurations are disclosed. In one embodiment, a CVT having axial force generation means at both the input and output elements is disclosed.

Abstract: A continuously variable transmission (CVT) having a main shaft configured to support and position various components of the CVT. Shift cam discs cooperate with ball-leg assemblies to shift the transmission ration of the CVT. Load cam discs, a torsion disc, rolling elements, and a hub cap shell are configured to generate axial force, transmit torque, and manage reaction forces. In one embodiment, a splined input shaft and a torsion disc having a splined bore cooperate to input torque into the variator of the CVT. Among other things, various ball axles, axle-ball combinations, and reaction force grounding configurations are disclosed. In one embodiment, a CVT having axial force generation means at both the input and output elements is disclosed.

Abstract: Inventive embodiments are directed to components, subassemblies, systems, and/or methods for continuously variable transmissions (CVT). In one embodiment, a main axle is adapted to receive a shift rod that cooperates with a shift rod nut to actuate a ratio change in a CVT. In another embodiment, an axial force generating mechanism can include a torsion spring, a traction ring adapted to receive the torsion spring, and a roller cage retainer configured to cooperate with the traction ring to house the torsion spring. Various inventive power roller-leg assemblies can be used to facilitate shifting the ratio of a CVT. Embodiments of a hub shell and a hub cover are adapted to house components of a CVT and, in some embodiments, to cooperate with other components of the CVT to support operation and/or functionality of the CVT. Among other things, shift control interfaces and braking features for a CVT are disclosed.