Abstract: The present disclosure relates to a solid, enzymatic detergent compositions and methods of making and using the same. In a preferred embodiment, the detergent compositions are particularly useful for cleaning medical and dental instruments. In a preferred embodiment the compositions are particularly use for cleaning ware.

Abstract: Methods and systems for managing and/or processing a blockchain to maintain data security for confidential and/or personal data are provided. According to certain aspects, the disclosed data security techniques may enable access sharing functionality utilizing the blockchain. For example, access sharing may be utilized to file documents, share policy information, and/or comply with an audit. The data security techniques disclosed herein also enable the use of smart contracts to transfer funds associated with payment obligations and/or other forms of blockchain based payments, comply with anti-money laundering requirements, report industry data, validate interest payments and/or maintain agent sales data. Data security may be achieved through the use of public key/private key encryption techniques.

Abstract: Devices and methods for determining item-specific information for single or multiple items on one or multiple substrates are described. The method includes generating multiple sensor multiple dimensions array (MSMDA) data from multiple sensors, where each of the multiple sensors capture sensor data for one or more items in relation to a substrate. For each item, the method includes determining relationships between the multiple sensors based on characteristics of the MSMDA data, determining a location of the item on the substrate based on at least the determined relationships between the multiple sensors, determining an angular orientation of the item on the substrate based on at least the determined relationships between the multiple sensors, and determining a body position of the subject on the substrate based at least the determined relationships between the multiple sensors, the location of the subject, and the angular orientation of the item.

Abstract: A pneumatic driver for a syringe is provided. The syringe has an elongated barrel with a cap secured to the proximal end that has a through bore. A filter is secured to the cap interior of the barrel that covers an opening in the through bore interior of the barrel. The pneumatic driver includes a source of pressurized air; a support for receiving and locating the syringe; and a supply block configured to receive pressurized air from the source and having an outlet for delivery of pressurized air. The supply block is movable between a first position spaced apart from the cap of the syringe and a second position in contact with the cap with fluid communication being established between the outlet of the supply block and the through-bore in the cap.

Abstract: A method of processing blood includes receiving from a touch screen user input data for a protocol for a wash procedure. The user input data includes a numeric value. The method includes storing the protocol in a memory, receiving an identifier from a user, determining if the identifier permits the user to modify the protocol and receiving a modification of the protocol from the user. The method includes providing a plurality of authorizations, a second authorization being a default and an administrator authorization permitting the user to change a setting. The method includes comparing a password to a password stored in memory and, if there is a match, determining that the password is associated with an administrator. If a command to change the setting is received, the command is applied to change the setting. The blood is processed employing a wash procedure using the modified protocol and the changed setting.

Abstract: A cell processing system includes at least one processor connectable to a source container filled with a biological fluid, the processor including a spinning membrane configured to receive and separate target cells from the biological fluid, the target cells exiting at a first outlet, first and second containers selectively connected to the first outlet; and a magnet. The system also includes a controller configured to operate the spinning membrane to receive biological fluid and to direct the target cells to the first container, to pause to permit magnetic particles to be associated with the target cells in the first container, to operate the spinning membrane to receive the contents of the first container with the magnet applied to the target cells associated with the magnetic particles, to remove or deactivate the magnet, and to transfer the target cells to the second container.

Abstract: IgM-multimerized single-domain antibodies that bind receptor tyrosine kinase (ROR1) are described. The IgM-multimerized single-domain antibodies can be used for multiple purposes including in research, imaging, diagnosis, and treatment of ROR1-related conditions and can be conjugated to form multi-domain binding molecules or antibody conjugates.

Abstract: An electric vehicle transmission includes a housing, a first gear, a second gear, and a first clutch pack supported in the housing. A first actuator is arranged in the housing. The first actuator is coupled with a first actuator member. A second actuator is arranged in the housing. The second actuator is coupled with a second actuator member. A modular actuation system is mounted to the housing. The modular actuation system includes a first energizer member and a second energizer member. The first energizer member is operatively connected to the first actuator and is operable to engage the first gear and the second energizer member is operatively connected to the second actuator and is operable to engage the second gear.

Abstract: A bearing rotary swivel joint preferably includes a swivel housing, a rotary swivel, an end plate, a solid bearing, a plurality of wear rings, a spring clip and a swivel seal. The swivel housing includes a threaded tube inlet and a swivel receiver bore. The rotary swivel includes a through bore, a threaded swivel inlet, a bearing diameter and an outer diameter. An O-ring groove is formed in the rotary swivel to receive the O-ring. The solid bearing is retained on the bearing diameter, terminated on each end with wear rings and axially retained with a spring clip against a bearing shoulder of the rotary swivel. The swivel seal is retained on the bearing diameter. The rotary swivel is inserted through a center bore in an end plate. The end plate is preferably fastened to the swivel housing with a plurality of fasteners.

Abstract: The present application provides bifunctional compounds of Formula (Ia) or (Ib): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which act as protein degradation inducing moieties for cyclin-dependent kinase 8 (CDK8). The present application also relates to methods for the targeted degradation of CDK8 through the use of the bifunctional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to CDK8 which can be utilized in the treatment of disorders modulated by CDK8.

Abstract: This document describes techniques for radio frequency (RF) based micro-motion tracking. These techniques enable even millimeter-scale hand motions to be tracked. To do so, radar signals are used from radar systems that, with conventional techniques, would only permit resolutions of a centimeter or more.

Abstract: In one implementation, a non-transitory computer-readable storage medium stores program instructions computer-executable on one or more processors of an electronic device to perform operations. The operations include presenting, on a display of the electronic device, a simulated reality (SR) environment at a first immersion level, where the first immersion level is associated with a first location of a reality boundary. Using a rotatable input device of the electronic device, input is received representing a request to change the first immersion level to a second immersion level. In accordance with receiving the input, the SR environment is presented at the second immersion level, where the second immersion level is associated with a second location of the reality boundary.

Abstract: A method of testing a braking system for an automotive vehicle that includes a master cylinder, a brake booster, a plurality of brake assemblies, a plurality of inlet valves, each inlet valve adapted to selectively allow brake fluid to flow into one of the plurality of brake assemblies and a plurality of outlet valves, each outlet valve adapted to selectively allow brake fluid to flow from one of the brake assemblies to a brake fluid reservoir, the method includes testing a first one of the plurality of inlet valves, testing a first one of the plurality of outlet valves, and sending diagnostic information to a controller within the automotive vehicle.

Abstract: A cell processing system includes a processor connectable to a source container filled with a biological fluid, the processor including a separator configured to separate the biological fluid from the source container into at least two streams according to a process including at least one process parameter, and a controller coupled to the processor and an input. The controller is configured to receive the at least one process parameter, to evaluate the process using the at least one process parameter before performing the process, and to carry out one or more actions based on the evaluation, such as providing an output estimate to the operator, preventing the process from being performed according to a comparison between a calculated condition and a control, or providing an error indication to the operator according to the calculated condition and a measured in-process condition.

Abstract: The present disclosure relates to techniques for displaying representations of physical input devices and overlaying visual features on the representations of physical input devices in a computer-generated reality (CGR) environment. The techniques include displaying a virtual application in a CGR environment and, in response to detecting an input field in the displayed virtual application, displaying at least a portion of the displayed application on a representation of a physical input device. The at least a portion of the displayed application includes the detected input field. In response to detecting an input received at the physical input device, the input field is updated with the input, and the updated input field is displayed.

Abstract: A system for measuring data specific to a subject using gravity comprises a substrate on which a subject lies, the substrate having multiple legs extending from the substrate to a floor to support the substrate, and load sensor assemblies. Each load sensor assembly is associated with a respective leg and comprises a cap configured to receive a load from the substrate, a base configured to provide contact with the floor, the base and cap configured to fit together to maintain alignment of the cap to the base while allowing vertical movement of the cap, a load cell between the base and the cap, one of the base and cap configured to translate the load to the load cell and a printed circuit board that processes and outputs data from the load cell, wherein a combination of all load sensor assemblies receive an entire load to which the substrate is subjected.

Abstract: The invention is generally related to Inflammatory Bowel Disease, Irritable Bowel Syndrome and other immune-mediated inflammatory disorders (IMIDs) such as rheumatoid arthritis, the spondyloarthritis disease spectrum, connective tissue disorders, cutaneous inflammatory conditions, asthma and autoimmune neurological diseases such as multiple sclerosis, and more particularly to compositions and methods for management and amelioration of symptoms in a subject in need thereof. One embodiment of the present invention contemplates a system and method useful for managing and ameliorating IBD symptoms resulting in the development of a personalized diet for the IBD participant which will reduce or eliminate most IBD symptoms.

Abstract: In one implementation, a non-transitory computer-readable storage medium stores program instructions computer-executable on a computer to perform operations. The operations include presenting, on a display of an electronic device, first content representing a standard view of a physical setting depicted in image data generated by an image sensor of the electronic device. While presenting the first content, an interaction with an input device of the electronic device is detected that is indicative of a request to present an enriched view of the physical setting. In accordance with detecting the interaction, second content is formed representing the enriched view of the physical setting by applying an enrichment effect that alters or supplements the image data generated by the image sensor. The second content representing the enriched view of the physical setting is presented on the display.

Abstract: In one implementation, a non-transitory computer-readable storage medium stores program instructions computer-executable on a computer to perform operations. The operations include presenting first content representing a virtual reality setting on a display of an electronic device. Using an input device of the electronic device, input is received representing a request to present a view corresponding to a physical setting in which the electronic device is located. In accordance with receiving the input, the first content is simultaneously presented on the display with second content representing the view corresponding to the physical setting obtained using an image sensor of the electronic device.

Abstract: This document describes techniques for radio frequency (RF) based micro-motion tracking. These techniques enable even millimeter-scale hand motions to be tracked. To do so, radar signals are used from radar systems that, with conventional techniques, would only permit resolutions of a centimeter or more.