Abstract: The estimator learning device contains an image acquisition unit that acquires stained images provided by photographing respectively in a plurality of wavebands a biomaterial sample that has been stained with a prescribed staining solution; a cell nucleus extraction unit that extracts a cell nucleus region present in the biomaterial sample in each of the stained images; a color information acquisition unit that calculates, for each of the stained images, an absorbance in each of the wavebands in the cell nucleus region; and an estimator learning unit that, based on a relationship between the absorbance in each of the wavebands and information associated with the biomaterial sample and relating to whether the cell nucleus present in the biomaterial sample is in a prescribed state, trains an estimator that estimates whether the cell nucleus is in the prescribed state from the absorbance in each of the wavebands.

Abstract: An automatic needle mover for moving a medical threaded needle includes: two shafts extending in the same direction and slidable relative to each other along a longitudinal direction; a needle-holding portion provided on one end side of the second shaft; a needle-receiving portion provided on one end side of the first shaft; and a handle serving as a control portion for controlling the sliding of the two shafts. The needle-holding portion has a first claw portion protruding in a direction intersecting the longitudinal direction of the shafts. The needle-receiving portion has a second claw portion protruding in a direction intersecting the longitudinal direction of the shafts. As a result of the sliding of the two shafts, the needle-holding portion and the needle-receiving portion become close to each other and a straight needle held by the needle-holding portion can be press-fitted into the needle-receiving portion.

Abstract: A method for obtaining an index for non-invasively identifying NASH is provided. A NASH determination method comprising a method for acquiring free radical consumption speed information by non-invasively detecting a redox reaction in a liver of a test animal in real time, comprises a step (1) of obtaining free radical concentration data by applying a magnetic resonance method to the liver as a measurement target after administering a probe into a body; a step (2) of obtaining imaging information by processing the obtained free radical concentration data; and a step (3) of obtaining a free radical consumption speed by kinetically measuring the imaging information over time, and comprises a step of determining whether or not the test animal has NASH, based on the free radical consumption speed information obtained through application to the test animal.

Abstract: A manipulator includes a base body, a first link supported to be capable of advancing and retracting with respect to the base body, a first leaf spring connected to a tip of the first link as a rotation pair by a first base end pin, a second link that is arranged with the first link side by side and is supported to be capable of advancing and retracting with respect to the base body, a second leaf spring connected to a tip of the second link as a rotation pair by a second base end pin in the same direction as the first base end pin, and a driven link that is connected to tips of the first and second leaf springs as rotation pairs by first and second tip pins in the same direction as the first and second base end pins, respectively.

Abstract: A fine work assistance system is configured such that a parallel link mechanism is used for a slave manipulator activated by a master operation, and a precise motion for microsurgery or the like is performed by remote control. In a slave unit of a master-slave manipulator, the parallel link mechanism with multiple degrees of freedom is used for a link mechanism in which an end effector is movable with respect to a base. Moreover, a tip operation part is driving by a hydraulic driving mechanism such that a plurality of linear actuators supported by the base move one ends of links so as to move the end effector, and the slave unit is activated in response to a user operation on the master unit. This achieves the precise motion of the end effector and causes the end effector to perform operations for a precise work.

Abstract: A manipulator includes a flexible actuating body, that includes a rectangular horizontal plate spring, a curved vertical plate spring which stands upright having a plate surface perpendicular to a plate surface of the horizontal plate spring, of which a base end is connected to one end of the horizontal plate spring in a longitudinal direction, which protrudes to one side in a width direction of the horizontal plate spring, which extends along the longitudinal direction of the horizontal plate spring, and of which a tip end in the extending direction is a portion bent in a direction opposite to the protruding direction, a shaft body which is connected to a tip end of the bent portion, and is rotatably supported at a center perpendicular to the plate surface of the horizontal plate spring, and an actuator protruding in a radius direction from an outer circumference of the shaft body.

Abstract: An operating portion which allows a bending treatment instrument to be inserted into an endoscope channel and bendably operated smoothly through intuition. The operating portion is connected with a device wire and bending wires and used to operate the treatment instrument and bend a freely bendable, bending treatment instrument, where the device wire is connected to a treatment instrument provided at a distal end of the bending treatment instrument and is used to operate the treatment instrument and the plurality of bending wires is used to bend the bending treatment instrument, the operating portion including: an operating portion body; a guide unit penetrated by the device wire; a bending wire pulling unit connected with the bending wires and swingably assembled onto the guide unit; and a grip portion connected with the device wire and configured to be reciprocable in an axial direction of the bending wire pulling unit.

Abstract: A fine work assistance system is configured such that a parallel link mechanism is used for a slave manipulator activated by a master operation, and a precise motion for microsurgery or the like is performed by remote control. In a slave unit of a master-slave manipulator, the parallel link mechanism with multiple degrees of freedom is used for a link mechanism in which an end effector is movable with respect to a base. Moreover, a tip operation part is driving by a hydraulic driving mechanism such that a plurality of linear actuators supported by the base move one ends of links so as to move the end effector, and the slave unit is activated in response to a user operation on the master unit. This achieves the precise motion of the end effector and causes the end effector to perform operations for a precise work.

Abstract: A method for obtaining an index for non-invasively identifying NASH is provided. A NASH determination method comprising a method for acquiring free radical consumption speed information by non-invasively detecting a redox reaction in a liver of a test animal in real time, comprises a step (1) of obtaining free radical concentration data by applying a magnetic resonance method to the liver as a measurement target after administering a probe into a body; a step (2) of obtaining imaging information by processing the obtained free radical concentration data; and a step (3) of obtaining a free radical consumption speed by kinetically measuring the imaging information over time, and comprises a step of determining whether or not the test animal has NASH, based on the free radical consumption speed information obtained through application to the test animal.

Abstract: A suture technique evaluation apparatus evaluates a suture technique performed on a simulated body simulating a part of the human body, and the suture technique evaluation apparatus includes a camera configured to image at least a suture region where suturing is performed on the simulated body, and a ligation force evaluation part adapted to evaluate the ligation force of the suturing on the basis of image data taken by the camera.

Abstract: A puncture assistance system provides information on a collapse state of a blood vessel to be punctured, caused by pressing action of an ultrasonic probe, when ultrasonic images of the blood vessel are acquired. A puncture assistance system 10 includes: vascular diameter detecting means 18 for detecting a vascular diameter during acquisition of the ultrasonic images from an ultrasonic diagnostic device 11; puncture assistance information generating means 12 for generating puncture assistance information for determination of whether or not puncture is allowed to be performed based on a collapse state of a blood vessel B caused by pressing action of an ultrasonic probe 15 against skin S by comparing a current vascular diameter detected by the vascular diameter detecting means 18 with a standard vascular diameter stored in advance; and a monitor 19 that presents the puncture assistance information.

Abstract: A puncture assistance system provides information on a collapse state of a blood vessel to be punctured, caused by pressing action of an ultrasonic probe, when ultrasonic images of the blood vessel are acquired. A puncture assistance system 10 includes: vascular diameter detecting means 18 for detecting a vascular diameter during acquisition of the ultrasonic images from an ultrasonic diagnostic device 11; puncture assistance information generating means 12 for generating puncture assistance information for determination of whether or not puncture is allowed to be performed based on a collapse state of a blood vessel B caused by pressing action of an ultrasonic probe 15 against skin S by comparing a current vascular diameter detected by the vascular diameter detecting means 18 with a standard vascular diameter stored in advance; and a monitor 19 that presents the puncture assistance information.

Abstract: In an apparatus for controlling the positioning of an object having a specified point, a first limiter establishes a movable range of the specified point of the object, and limits movement of the specified point of the object within the movable range. The movable range includes a line connecting the position of the specified point of the object and a target position for the specified point of the object. A second limiter limits change of a specified orientation of the object from increasing an angular difference between the specified orientation of the object a target orientation for the specified orientation of the object.

Abstract: The present invention provides a fluorescent molecular probe for efficient fluorescent detection (visualization) of tumors or for implementing fluorescent detection and photodynamic treatment, more specifically, the present invention provides a macromolecular fluorescent molecular probe for fluorescent detection of tumor, comprising a complex comprising a fluorescent molecule and a biocompatibie macromolecule.

Abstract: A diagnostic system comprises a spectral image shooting means that shoots a spectral image within a predetermined wavelength range in a body cavity and obtains spectral image data, an image processing means that obtains the spectral image data and calculates an indicator indicating an area having a high possibility of a diseased portion from the spectral image data, and a monitor on which the indicator is displayed, and wherein the image processing means calculates, as the indicator, a ratio between an accumulated value of intensity values of all spectral images in the predetermined wavelength range and an intensity value of spectral images in a particular wavelength band, for each coordinate in the spectral image.

Abstract: A suture technique evaluation apparatus evaluates a suture technique performed on a simulated body simulating a part of the human body, and the suture technique evaluation apparatus includes a camera configured to image at least a suture region where suturing is performed on the simulated body, and a ligation force evaluation part adapted to evaluate the ligation force of the suturing on the basis of image data taken by the camera.

Abstract: An image completion system includes a first endoscope for obtaining an operating field image, a second endoscope for imaging the object space in a line-of-sight direction different from that of the first endoscope to obtain a completing image, a first device for measuring separating distances between a reference point and a large number of set points that are set in the object space, a second device for measuring three-dimensional positions of the endoscopes, and an image processing device for obtaining, image information on cutoff regions in the object space that are hidden on the depth sides of surgical instruments by imaging the surgical instruments in the operating field image together with the object space, and for replacing image information on the surgical instruments S in the operating field image with the obtained image information or superimposing the obtained image information onto the image information on the surgical instruments.

Abstract: A control device for a lockup clutch of a vehicle. A slip control device executes slip control to make a rotational speed difference between the input member and the input shaft match a target slip speed according to a state of the vehicle by half engagement of the lockup clutch. A clutch temperature obtaining means obtains a clutch temperature of the lockup clutch. A determining means determines if the lockup clutch should be fully engaged or disengaged based on at least a state of the motor if the clutch temperature becomes equal to or higher than a predetermined temperature during execution of the slip control. A slip control stop means for stopping the slip control by fully engaging or disengaging the lockup clutch according to the determination result of the determining means.

Abstract: A mouth opening instrument includes an upper member suitable for attaching on an upper jaw side within the mouth of a patient and a lower member suitable for attaching on a lower jaw side. The instrument further includes a connecting section, a control section, and an input section. The connecting section connects end portions of the upper member and the lower member such that a resistance of opening or closing actions of the upper member and the lower member are controllable. The control section controls the resistance of opening or closing actions of the upper member and the lower member. The input section receives an operating state signal indicating an operating state of a dental treatment device. When the operating state signal indicating an operating state of a dental treatment device is inputted, the closing resistance of the upper member and the lower member is set to be greater than that at a time when the operating state signal is not inputted.

Abstract: A lock-up device supplies hydraulic pressure to a lock-up clutch when lock-up capacity becomes insufficient with increasing accelerator operation amount during slip control. The lock-up device (1) sets a hydraulic unit pressure command value corresponding to drive source torque so rotational speed difference becomes target slip speed when a variation in accelerator operation amount is in a predefined range, and deriving an estimated drive source output torque corresponding to the accelerator operation amount to set the pressure command value corresponding to the estimated drive source torque so the rotational speed difference becomes target slip speed when accelerator operation amount variation exceeds the range's upper limit, and (2) controls the hydraulic unit to supply hydraulic pressure corresponding to hydraulic pressure command value to the lock-up clutch.