Abstract: An automatic needle mover for moving a medical threaded needle includes: two shafts extending in the same direction and slidable relative to each other along a longitudinal direction; a needle-holding portion provided on one end side of the second shaft; a needle-receiving portion provided on one end side of the first shaft; and a handle serving as a control portion for controlling the sliding of the two shafts. The needle-holding portion has a first claw portion protruding in a direction intersecting the longitudinal direction of the shafts. The needle-receiving portion has a second claw portion protruding in a direction intersecting the longitudinal direction of the shafts. As a result of the sliding of the two shafts, the needle-holding portion and the needle-receiving portion become close to each other and a straight needle held by the needle-holding portion can be press-fitted into the needle-receiving portion.

Abstract: A method for obtaining an index for non-invasively identifying NASH is provided. A NASH determination method comprising a method for acquiring free radical consumption speed information by non-invasively detecting a redox reaction in a liver of a test animal in real time, comprises a step (1) of obtaining free radical concentration data by applying a magnetic resonance method to the liver as a measurement target after administering a probe into a body; a step (2) of obtaining imaging information by processing the obtained free radical concentration data; and a step (3) of obtaining a free radical consumption speed by kinetically measuring the imaging information over time, and comprises a step of determining whether or not the test animal has NASH, based on the free radical consumption speed information obtained through application to the test animal.

Abstract: The estimator learning device contains an image acquisition unit that acquires stained images provided by photographing respectively in a plurality of wavebands a biomaterial sample that has been stained with a prescribed staining solution; a cell nucleus extraction unit that extracts a cell nucleus region present in the biomaterial sample in each of the stained images; a color information acquisition unit that calculates, for each of the stained images, an absorbance in each of the wavebands in the cell nucleus region; and an estimator learning unit that, based on a relationship between the absorbance in each of the wavebands and information associated with the biomaterial sample and relating to whether the cell nucleus present in the biomaterial sample is in a prescribed state, trains an estimator that estimates whether the cell nucleus is in the prescribed state from the absorbance in each of the wavebands.

Abstract: A manipulator includes a base body, a first link supported to be capable of advancing and retracting with respect to the base body, a first leaf spring connected to a tip of the first link as a rotation pair by a first base end pin, a second link that is arranged with the first link side by side and is supported to be capable of advancing and retracting with respect to the base body, a second leaf spring connected to a tip of the second link as a rotation pair by a second base end pin in the same direction as the first base end pin, and a driven link that is connected to tips of the first and second leaf springs as rotation pairs by first and second tip pins in the same direction as the first and second base end pins, respectively.

Abstract: A fine work assistance system is configured such that a parallel link mechanism is used for a slave manipulator activated by a master operation, and a precise motion for microsurgery or the like is performed by remote control. In a slave unit of a master-slave manipulator, the parallel link mechanism with multiple degrees of freedom is used for a link mechanism in which an end effector is movable with respect to a base. Moreover, a tip operation part is driving by a hydraulic driving mechanism such that a plurality of linear actuators supported by the base move one ends of links so as to move the end effector, and the slave unit is activated in response to a user operation on the master unit. This achieves the precise motion of the end effector and causes the end effector to perform operations for a precise work.

Abstract: An automatic needle mover (1) for moving a medical threaded needle includes: two shafts (a first shaft (11) and a second shaft (12)) extending in the same direction and slidable relative to each other along a longitudinal direction; a needle holding portion (a second needle support portion (22)) provided on one end side of the second shaft (12); a needle-receiving portion (a first needle support portion (21)) provided on one end side of the first shaft (11); and a handle (30) serving as a control portion for controlling the sliding of the two shafts. The needle holding portion has a first groove portion provided in a first claw portion protruding in a direction intersecting the longitudinal direction of the shafts. The needle-receiving portion has a second groove portion provided in a second claw portion protruding in a direction intersecting the longitudinal direction of the shafts.

Abstract: A manipulator includes a flexible actuating body, that includes a rectangular horizontal plate spring, a curved vertical plate spring which stands upright having a plate surface perpendicular to a plate surface of the horizontal plate spring, of which a base end is connected to one end of the horizontal plate spring in a longitudinal direction, which protrudes to one side in a width direction of the horizontal plate spring, which extends along the longitudinal direction of the horizontal plate spring, and of which a tip end in the extending direction is a portion bent in a direction opposite to the protruding direction, a shaft body which is connected to a tip end of the bent portion, and is rotatably supported at a center perpendicular to the plate surface of the horizontal plate spring, and an actuator protruding in a radius direction from an outer circumference of the shaft body.

Abstract: An operating portion which allows a bending treatment instrument to be inserted into an endoscope channel and bendably operated smoothly through intuition. The operating portion is connected with a device wire and bending wires and used to operate the treatment instrument and bend a freely bendable, bending treatment instrument, where the device wire is connected to a treatment instrument provided at a distal end of the bending treatment instrument and is used to operate the treatment instrument and the plurality of bending wires is used to bend the bending treatment instrument, the operating portion including: an operating portion body; a guide unit penetrated by the device wire; a bending wire pulling unit connected with the bending wires and swingably assembled onto the guide unit; and a grip portion connected with the device wire and configured to be reciprocable in an axial direction of the bending wire pulling unit.

Abstract: A manipulator includes a pair of flexible operating bodies including a horizontal plate spring, a curved vertical plate spring, a shaft body, and an operation portion. The pair of flexible operating bodies overlaps such that a second flexible operating body on one side is opposite to a first flexible operating body on the other side, and is linked to each other to be rotatable by a pin penetrating respective shaft bodies. In a holder that supports both ends of the pin, a pair of outer horizontal plate springs that has the horizontal plate springs of each of the pair of flexible operating bodies to be interposed in parallel between the holder and extends in the same direction as the horizontal plate spring is integrally formed.

Abstract: A fixing device for an endoscope that allows easy detachment of the endoscope from an endoscope holder even with the endoscope kept inserted in a body cavity is provided. A fixing device for fixing an endoscope capable of observing an operative site in a body cavity using an endoscope having an insertion portion to be inserted into the body cavity and an endoscope body attached at an end of the insertion portion. The fixing device includes a holder body which is attached to a fixing stand placed on a floor and holds the endoscope body in a rotatable manner. The holder body includes a detaching mechanism that allows the endoscope body to be detached from the holder body while keeping the insertion portion inserted in the body cavity.

Abstract: A fixing stand to which an endoscope body and treatment instruments can be easily attached in an easy-to-operate manner and which facilitates increase or decrease in the number of such items is provided. A fixing stand includes legs and a fixing stand body erected on the legs, the fixing stand allowing at least one or more of an endoscope body of an endoscope and an operation input portion of a treatment instrument for use in a surgery to be attached to the fixing stand in a detachable manner. The endoscope body and the operation input portion are attached to fixtures which are disposed side by side substantially horizontally to the direction in which the fixing stand is erected. The fixtures are detachably attached to a fixing base which extends substantially horizontally to the fixing stand body. A hanger component is further attached to the fixing base.

Abstract: A fine work assistance system is configured such that a parallel link mechanism is used for a slave manipulator activated by a master operation, and a precise motion for microsurgery or the like is performed by remote control. In a slave unit of a master-slave manipulator, the parallel link mechanism with multiple degrees of freedom is used for a link mechanism in which an end effector is movable with respect to a base. Moreover, a tip operation part is driving by a hydraulic driving mechanism such that a plurality of linear actuators supported by the base move one ends of links so as to move the end effector, and the slave unit is activated in response to a user operation on the master unit. This achieves the precise motion of the end effector and causes the end effector to perform operations for a precise work.

Abstract: A method for obtaining an index for non-invasively identifying NASH is provided. A NASH determination method comprising a method for acquiring free radical consumption speed information by non-invasively detecting a redox reaction in a liver of a test animal in real time, comprises a step (1) of obtaining free radical concentration data by applying a magnetic resonance method to the liver as a measurement target after administering a probe into a body; a step (2) of obtaining imaging information by processing the obtained free radical concentration data; and a step (3) of obtaining a free radical consumption speed by kinetically measuring the imaging information over time, and comprises a step of determining whether or not the test animal has NASH, based on the free radical consumption speed information obtained through application to the test animal.

Abstract: A manipulator includes a base body, a first link supported to be capable of advancing and retracting with respect to the base body, a first leaf spring connected to a tip of the first link as a rotation pair by a first base end pin, a second link that is arranged with the first link side by side and is supported to be capable of advancing and retracting with respect to the base body, a second leaf spring connected to a tip of the second link as a rotation pair by a second base end pin in the same direction as the first base end pin, and a driven link that is connected to tips of the first and second leaf springs as rotation pairs by first and second tip pins in the same direction as the first and second base end pins, respectively.

Abstract: A manipulator includes a flexible actuating body, that includes a rectangular horizontal plate spring, a curved vertical plate spring which stands upright having a plate surface perpendicular to a plate surface of the horizontal plate spring, of which a base end is connected to one end of the horizontal plate spring in a longitudinal direction, which protrudes to one side in a width direction of the horizontal plate spring, which extends along the longitudinal direction of the horizontal plate spring, and of which a tip end in the extending direction is a portion bent in a direction opposite to the protruding direction, a shaft body which is connected to a tip end of the bent portion, and is rotatably supported at a center perpendicular to the plate surface of the horizontal plate spring, and an actuator protruding in a radius direction from an outer circumference of the shaft body.

Abstract: A suture technique evaluation apparatus evaluates a suture technique performed on a simulated body simulating a part of the human body, and the suture technique evaluation apparatus includes a camera configured to image at least a suture region where suturing is performed on the simulated body, and a ligation force evaluation part adapted to evaluate the ligation force of the suturing on the basis of image data taken by the camera.

Abstract: A puncture assistance system provides information on a collapse state of a blood vessel to be punctured, caused by pressing action of an ultrasonic probe, when ultrasonic images of the blood vessel are acquired. A puncture assistance system 10 includes: vascular diameter detecting means 18 for detecting a vascular diameter during acquisition of the ultrasonic images from an ultrasonic diagnostic device 11; puncture assistance information generating means 12 for generating puncture assistance information for determination of whether or not puncture is allowed to be performed based on a collapse state of a blood vessel B caused by pressing action of an ultrasonic probe 15 against skin S by comparing a current vascular diameter detected by the vascular diameter detecting means 18 with a standard vascular diameter stored in advance; and a monitor 19 that presents the puncture assistance information.

Abstract: An operating portion which allows a bending treatment instrument to be inserted into an endoscope channel and bendably operated smoothly through intuition. The operating portion is connected with a device wire and bending wires and used to operate the treatment instrument and bend a freely bendable, bending treatment instrument, where the device wire is connected to a treatment instrument provided at a distal end of the bending treatment instrument and is used to operate the treatment instrument and the plurality of bending wires is used to bend the bending treatment instrument, the operating portion including: an operating portion body; a guide unit penetrated by the device wire; a bending wire pulling unit connected with the bending wires and swingably assembled onto the guide unit; and a grip portion connected with the device wire and configured to be reciprocable in an axial direction of the bending wire pulling unit.

Abstract: A hinge member of a bending treatment instrument in an endoscope channel and used bendably and capable of withstanding loads from grasping and resection motions of treatment instruments and a bending treatment instrument that uses the hinge member. Tubular hinge members arranged in a row substantially coaxially with one another make up the instrument and a hinge member includes: two recesses on edges of an end face on a proximal side in an axial direction; and two projections on an edge of an end face on a distal side shifted 90 degrees in a circumferential direction from the recess and facing each other in radial direction, wherein a bending-wire passage hole penetrating the hinge member in the axial direction is at a position avoiding the projections on the end face on the distal side, and a device-wire passage hole penetrating an axial center portion.

Abstract: A puncture assistance system provides information on a collapse state of a blood vessel to be punctured, caused by pressing action of an ultrasonic probe, when ultrasonic images of the blood vessel are acquired. A puncture assistance system 10 includes: vascular diameter detecting means 18 for detecting a vascular diameter during acquisition of the ultrasonic images from an ultrasonic diagnostic device 11; puncture assistance information generating means 12 for generating puncture assistance information for determination of whether or not puncture is allowed to be performed based on a collapse state of a blood vessel B caused by pressing action of an ultrasonic probe 15 against skin S by comparing a current vascular diameter detected by the vascular diameter detecting means 18 with a standard vascular diameter stored in advance; and a monitor 19 that presents the puncture assistance information.