Abstract: Described is a unique class of antiviral molecule that can be applied to control and eliminate HIV infection in patients using myeloablation therapies and replenishment with transformed bone marrow stem cells programmed to express the antiviral molecule. These anti-viral molecules target the HIV genome in a highly conserved domain, and when expressed in cells prior to infection will cause the cell to die upon infection with HIV. Cell death insures no proliferation of new virus. Reconstituting the immune system with cells expressing these antivirals prevents re-establishment of HIV infection from reservoirs in the re-established lymphocyte and macrophage populations. Over time, reservoirs will be depleted entirely, effectively eliminating the virus. In effect, this new type of antiviral can be used to cure HIV infections.

Abstract: A processing device and a machine-implemented method may be provided for tracking file system dependencies with respect to a volume residing on a storage device and guest volumes residing on virtual storage devices nested within the volume. A shim driver may receive an indication of a virtual storage device being surfaced and may parse contents to surface partitions and volumes contained within the virtual storage device to a system. The shim driver may open a guest volume nested within a host volume and may send a register request, regarding the guest volume, to a virtual disk mini-filter associated with the host volume. The virtual disk mini-filter may save information regarding a relationship between the host volume and the guest volume. The saved information may be used to prevent file system corruption when the host volume is dismounted or unexpectedly removed.

Abstract: A hybrid input differential engine system comprising a planetary gear set. Preferably, an ICE is connected to the planet gear carrier, the output shaft is connected to the ring gear, and the sun gear is connected to a supercharger/expander and an electric or hydraulic motor/generator. As engine torque increases, the supercharger speeds up, increasing torque still further, enabling a small displacement engine to have very high torque at low RPM. In cruise conditions, the sun gear direction is reversed by the motor/generator, causing the supercharger to act as an expander for efficiently throttling the engine. The motor/generator modulates the speed/torque relationships between the engine and the supercharger/expander. A second motor/generator may be used on the output shaft. The electric machines and electric storage may be downsized because less electrical power is needed for the operation of the system.

Abstract: A method of operating a fuel cell system on a by-product gas containing a fuel constituent. The fuel cell system includes a fuel reformer for forming a reformate stream, a combustor for supplying heat energy to the fuel reformer, and a fuel cell stack. The method includes the steps of separating a by-product gas into a purified gas stream and a residual stream with a gaseous fuel purifier, feeding the purified gas stream to the fuel reformer configured to transform the purified gas stream to produce a reformate stream, and feeding the residual gas stream to a combustor configured to provide heat energy to the fuel reformer. The purified gas stream contains a higher concentration of preferable fuel constituents and a lower concentration of contaminants than the residual gas stream.

Abstract: Aspects of the subject matter described herein relate to virtualization and offload reads and writes. In aspects, an offload read allows a requestor to obtain a token that represents data while an offload write allows the requestor to request that the data (or a part thereof) represented by a token be logically written. Offload reads and writes may be used to perform various actions for virtual environments.

Abstract: Aspects of the subject matter described herein relate to offload reads and writes. In aspects, a requestor that seeks to transfer data sends a request for a representation of the data. In response, the requestor receives one or more tokens that represent the data. The requestor may then provide one or more of these tokens to a component with a request to write data represented by the one or more tokens. In some exemplary applications, the component may use the one or more tokens to identify the data and may then read the data or logically write the data without additional interaction with the requestor. Tokens may be invalidated by request or based on other factors.

Abstract: The invention is directed to a clothing article or apparel for identifying a post operative or recovering person, the clothing article or apparel having one or more signs capable of indicating to the general public that the patient is recovering from surgery, the one or more signs being visible from more than one side of the discharged patient. Typically, the clothing article or apparel is adapted to be worn outside clothing and the one or more signs are visible from several metres away. Preferably, the clothing article or apparel is padded or comprises retention means for padding.

Abstract: Methods are disclosed for decreasing calorie intake, food intake, and appetite in a subject. The methods include peripherally administering PYY or an agonist thereof and GLP-1 or an agonist thereof to the subject, simultaneously or sequentially, thereby decreasing the calorie intake of the subject.

Abstract: Methods are disclosed for decreasing calorie intake, food intake, and appetite in a subject. The methods include peripherally administering PYY or an agonist thereof and GLP-1 or an agonist thereof to the subject, simultaneously or sequentially, thereby decreasing the calorie intake of the subject.

Abstract: During periods of vehicle inactivity, a vehicle-based APU electric generating system may be coupled into a regional electric grid to send electricity into the grid. A currently-preferred APU is a solid oxide fuel cell system. When a large number of vehicles are thus equipped and connected, substantial electric buffering can be effected to the grid load. A vehicle-based APU can also function as a back-up generator to a docking facility in the event of power failure of the grid. Gaseous hydrocarbon is readily supplied by pipe in many locations as a commercial and residential heating fuel source, and a hydrocarbon reformer on the vehicle can be attached to the fuel source, enabling an APU to operate as a stationary power source indefinitely. An optional storage tank on the vehicle may be refueled with gaseous fuel, for example, while the battery is being electrically recharged by the grid.

Abstract: An energy conversion system comprising ammonia for fueling an SOFC stack to generate electricity and a hydrogen-rich tailgas. In the SOFC stack, ammonia is cracked to hydrogen and nitrogen. Ammonia is stored in a metal halide complex and is released therefrom as gaseous ammonia by waste heat from the SOFC. A heat exchanger is positioned across the SOFC cathode such that incoming air is tempered by the cathode exhaust air. In a two-stage energy conversion system, the hydrogen-rich tailgas from the SOFC is supplied as fuel to a secondary energy conversion device which may be, for example, an internal combustion engine or a gas turbine engine which may operate, for example, either a generator for generating additional electricity or a vehicle for motive power, or a second fuel cell stack.

Abstract: A system comprising a cylindrical housing containing a sorbent cartridge selective of one or more gases in a gaseous mixture. End caps on opposite ends of the housing seal to the ends of the cartridge and direct the flow of gas mixture through a portion of the cartridge. The first end cap has entrance and exit ports for the gas mixture and for a purging gas for cartridge regeneration. The second end cap includes a compartment to receive and return the gas mixture to the first cap exit port. The purging gas follows a similar pathway via the remaining portion of the cartridge. The cartridge is rotatable within the housing; thus, the exhausted portion of the medium may be rotated into position for regeneration while a regenerated portion of the medium is rotated into position for re-use, thus providing continuous adsorption from the gas mixture.

Abstract: A hybrid fuel cell system comprising a solid-oxide fuel cell system, a proton exchange membrane fuel cell system, a hydrocarbon reformer and a hydrogen separator. A large PEM provides output power, such as motive power for a vehicle, using hydrogen storage that may be resupplied from a separate hydrogen refilling station or from the onboard reformer. The SOFC is preferably small and provides heat and exhaust water that, when recycled into the reformer, allow the reformer to operate endothermically without requiring atmospheric air, thus excluding nitrogen from the reformate stream. Alternatively, the reformer and SOFC are stationary at a base station and the PEM is aboard the vehicle. The SOFC and reformer have sufficient capacity to recharge hydrogen storage in the vehicle in a relatively short period of time, such as overnight.

Abstract: A system for removing sulfur from a continuous reformate stream feeding a fuel cell stack. First and second sulfur traps are disposed in parallel between a hydrocarbon reformer and the fuel cell stack. The ends of the sulfur traps are connected to conventional four-way valves such that either trap may be selected for trapping sulfur from the reformate stream, while the other trap is undergoing regeneration by backflushing the accumulated adsorbed sulfur deposits. Thus, the sulfur traps may be used and stripped alternately, permitting continuous supply of desulfurized reformate to the fuel cell assembly. In a currently preferred embodiment, the hot cathode air exhaust is used to assist in stripping the out-of-service trap. In an alternative embodiment, two reformers are provided and the reformers are alternately regenerated along with their respective traps.

Abstract: The present invention provides a method for identifying a microarray probe set capable of identifying a member of a group of related nucleotide sequences, the method comprising the steps of providing a candidate probe set comprising at least one probe capable of differentially hybridizing to two or more members of the group of related nucleotide sequences, testing reactivity of the probe set against two or more members of the group of related nucleotide sequences, and observing the degree of difference in the patterns of reactivity of the probe set for the two or more members of the group of related nucleotide sequences.

Abstract: A system renders at least one content library in an organization region. The content library represents content that is accessible via a policy. The system receives a selection to obtain the content represented by the content library, and renders content information that represents a listing of the content contained within the content library. The content information is displayed within a listing region wherein the content may be accessible via the policy. The system downloads the content for which access has been granted via the policy. The content is downloaded from a content source provider.

Abstract: The present invention provides methods for obtaining epigenetic information for a polyploid subject, the method including the steps of obtaining a biological sample from the subject, the sample containing: (i) at least one paternally-derived DNA molecule and/or associated protein and/or, (ii) at least one maternally-derived DNA molecule and/or associated protein, analyzing any one or more of the paternally- or maternally-derived DNA molecules or associated proteins for the presence or absence of modifications, wherein the step of analyzing determines whether any two modifications are present in cis on one chromosome, or in trans across two sister chromosomes.

Abstract: A hybrid fuel cell system comprising a solid-oxide fuel cell system, a proton exchange membrane fuel cell system, a hydrocarbon reformer and a hydrogen separator. A large PEM provides output power, such as motive power for a vehicle, using hydrogen storage that may be resupplied from a separate hydrogen refilling station or from the onboard reformer. The SOFC is preferably small and provides heat and exhaust water that, when recycled into the reformer, allow the reformer to operate endothermically without requiring atmospheric air, thus excluding nitrogen from the reformate stream. Alternatively, the reformer and SOFC are stationary at a base station and the PEM is aboard the vehicle. The SOFC and reformer have sufficient capacity to recharge hydrogen storage in the vehicle in a relatively short period of time, such as overnight.

Abstract: A boost system comprising a turbocharger, a supercharger operable as either a compressor or an expander. Air flows through the turbocharger, optionally through a first charge air cooler CAC1, then through the supercharger, a second charge air cooler CAC2, and into the engine. At low engine speeds, the supercharger may be used to compress air, which is tempered by CAC2. At high engine speeds, the turbocharger has excess capacity, resulting in a hot compressed air stream. The supercharger operates as an expander to cool the air stream and reduce the air pressure and temperature to a desired level. Temperature may be reduced to a level below that desired for combustion; CAC2 then rewarms the air, thereby storing cooling capacity. A useful embodiment incorporates a turbocharger with a hybrid gas/electric or diesel/electric engine arrangement wherein a supercharger and a starter/generator/motor are disposed on a disconnectable secondary drive powered by the engine.

Abstract: The present invention provides a method for identifying a set of target nucleotide sequences capable of identifying a member of a group of related nucleotide sequences, the method comprising the step of dividing the nucleotide sequence of each member of the group into a plurality of subsequences, wherein at least two of the subsequences overlap. The method is useful in generating probe sets capable of assigning alleles at HLA or KIR loci.