Patents by Inventor Man Chen
Man Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260146077Abstract: Disclosed are monoclonal antibodies, antigen binding fragments, and bi-specific antibodies that specifically bind SARS-CoV-2. Also disclosed is the use of these antibodies for inhibiting a coronavirus infection, such as a SARS-CoV-2 infection. In addition, disclosed are methods for detecting a coronavirus, such as SARS-CoV-2, in a biological sample, using the disclosed antibodies. In some embodiments, the SARS-CoV-2 is the BA.4 or BA.5 variant.Type: ApplicationFiled: September 6, 2023Publication date: May 28, 2026Applicant: The U.S.A., as represented by the Secretary, Department of Health and Human ServicesInventors: John Nicholas Misasi, Lingshu Wang, Nancy J. Sullivan, John R. Mascola, Misook Choe, Tongqing Zhou, Peter D. Kwong, Richard Alan Koup, Wei Shi, Eun Sung Yang, Yi Zhang, Man Chen
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Patent number: 12634215Abstract: The present disclosure relates to method for cloud-edge data transmission of an electrochemical energy storage station, including: caching the first data to be transmitted and sending a connection re-establishment request to the cloud node; sending second data to be transmitted to the cloud node; sending the cached first data to the cloud node in an idle period after the first period; determining a characteristic value of third data to be transmitted, sending the characteristic value to the cloud node, and caching a non-characteristic value apart from the characteristic value, in a case where an abnormal working condition of the edge node is detected; sending to the cloud node fourth data to be transmitted; and sending the non-characteristic value of the third data to the cloud node in an idle period after the second period.Type: GrantFiled: October 6, 2023Date of Patent: May 19, 2026Assignee: CSG PGC ENERGY STORAGE RESEARCH INSTITUTEInventors: Hao Zhang, Man Chen, Yumin Peng, Yikai Li, Zengtao Zhao, Fanqi Huang, Peng Peng, Zhenkai Hu, Wanzhou Sun, Jun She, Xiaoyi Wang
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Publication number: 20260118432Abstract: The present application provides a fault detection isolation and positioning method for a general battery system, only voltage and current data commonly used currently can be utilized to detect, isolate, and position multiple types of faults, including a voltage sensor fault, a current sensor fault, a loose contact, and an electrical core fault.Type: ApplicationFiled: November 19, 2024Publication date: April 30, 2026Applicant: CSG PGC ENERGY STORAGE RESEARCH INSTITUTEInventors: Rui XIONG, Chenxu WANG, Man CHEN, Hao ZHANG, Yikai LI, Siwei YU, Zihao LIU, Zhuoyi LI, Peng PENG, Yumin PENG, Wanzhou SUN, Jun SHE, Xiaoyi WANG
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Publication number: 20250388627Abstract: Embodiments of a recombinant Respiratory Syncytial Virus (RSV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the RSV F ectodomain trimer and methods of producing the RSV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the recombinant RSV F ectodomain trimer to the subject.Type: ApplicationFiled: January 17, 2025Publication date: December 25, 2025Applicant: The United States of America, as represented by the Secretary, Department of Health and Human ServicInventors: Peter Kwong, Barney Graham, John Mascola, Li Ou, Aliaksandr Druz, Man Chen, Wing-Pui Kong, Ivelin Stefanov Georgiev, Emily Rundlet, Michael Gordon Joyce, Yaroslav Tsybovsky, Paul Thomas, Marie Pancera, Mallika Sastry, Cinque Soto, Joseph Van Galen, Guillaume Stewart-Jones, Yongping Yang, Baoshan Zhang, Ulrich Baxa
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Patent number: 12492980Abstract: Disclosed are an antibody combination for one-step screening and/or diagnosis of clonal diseases and application thereof. The antibody combination includes eight groups of antibodies, and is a set of flow cytometry detection panels for one-step screening and/or diagnosis of clonal diseases, and 5-tube parallel is used for one sample, the first group of antibodies and the second group of antibodies are used for samples in different flow cytometry tubes, the third group of antibodies and the sixth group of antibodies are used for samples in the same flow cytometry tube, the fourth group of antibodies and the seventh group of antibodies are used for samples in the same flow cytometry tube, and the fifth group of antibodies and the eighth group of antibodies are used for samples in the same flow cytometry tube.Type: GrantFiled: August 3, 2022Date of Patent: December 9, 2025Assignees: SYNARC RESEARCH LABORATORY (BEIJING) LTD., HEBEI YANDA LU DAOPEI HOSPITALInventors: Hui Wang, Man Chen, Aixian Wang, Meiwei Gong, Xueying Wu, Junyi Zhen, Qing Du, Ya Guo
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Publication number: 20250368690Abstract: Disclosed are Respiratory Syncytial Virus (RSV) antigens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the antigens and methods of producing the antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject.Type: ApplicationFiled: December 30, 2024Publication date: December 4, 2025Applicant: The United States of America, as represented by the Secretary, Department of Health and Human ServicInventors: Peter D. Kwong, Barney S. Graham, Jason S. McLellan, Jeffrey Boyington, Lei Chen, Man Chen, Gwo-Yu Chuang, Ivelin Stefanov Georgiev, Jason Gorman, Michael Gordon Joyce, Masaru Kanekiyo, Gilad Ofek, Marie Pancera, Mallika Sastry, Cinque Soto, Sanjay Srivatsan, Guillaume Stewart-Jones, Yongping Yang, Baoshan Zhang, Tongqing Zhou
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Patent number: 12347295Abstract: A method and device for smoke or fire recognition, a computer device and a storage medium are disclosed. The method includes: acquiring a to-be-recognized image in a smoke or fire monitoring region; recognizing a smoke or fire suspected region in the to-be-recognized image according to the to-be-recognized image, including recognizing a smoke or fire suspected region in a visible light image on the basis of colors, and recognizing a smoke or fire suspected region in an infrared image on the basis of brightness; and inputting the to-be-recognized image including the smoke or fire suspected region into a preset model, and recognizing a smoke or fire state in the to-be-recognized image according to an output result of the preset model, the preset model being obtained by training based on the visible light image pre-marked with a smoke or fire state or the infrared image pre-marked with a smoke or fire state.Type: GrantFiled: March 5, 2021Date of Patent: July 1, 2025Assignee: CSG POWER GENERATION CO., LTD.Inventors: Liqun Sun, Man Chen, Hao Zhang, Yong Lu, Tao Liu, Ming Xu, Jianhui Li, Miaogeng Wang, Zhipeng Lv, Kai Lin, Yulin Han, Yu Gong, Haifeng Guo, Xiaoyi Wang, Hanlong Wang, Rufei He
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Patent number: 12275758Abstract: Embodiments of a recombinant Respiratory Syncytial Virus (RSV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the RSV F ectodomain trimer and methods of producing the RSV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the recombinant RSV F ectodomain trimer to the subject.Type: GrantFiled: January 10, 2024Date of Patent: April 15, 2025Assignee: The United States of America, as represented by the Secretary, Department of Health and Human ServicesInventors: Peter Kwong, Barney Graham, John Mascola, Li Ou, Aliaksandr Druz, Man Chen, Wing-Pui Kong, Ivelin Stefanov Georgiev, Emily Rundlet, Michael Gordon Joyce, Yaroslav Tsybovsky, Paul Thomas, Marie Pancera, Mallika Sastry, Cinque Soto, Joseph Van Galen, Guillaume Stewart-Jones, Yongping Yang, Baoshan Zhang, Ulrich Baxa
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Publication number: 20250079568Abstract: Disclosed is a fully immersed energy storage device, which includes a casing and a water pump. An insulation box is mounted inside the casing, and the insulation box is assembled with an assembly plate thereon. A mounting platform is mounted on the assembly plate and assembled with an annular rack. A rotating groove is provided between the mounting platform and the annular rack. Balls are placed in the rotating groove. The mounting platform is assembled with an assembly block, on which a rotating shaft is mounted. One end of the rotating shaft connects to a gear. The other end of the rotating shaft connects to a first assembly rod, to which a second assembly rod is connected. The second assembly rod connects to a fixed block, which is connected to an energy storage box. A motor base is mounted on the casing. A motor is mounted on the motor base.Type: ApplicationFiled: August 15, 2023Publication date: March 6, 2025Applicant: CSG PWR GEN (GUANGDONG) ENERGY STOR TECH CO., LTDInventors: Zhiqiang WANG, Chao DONG, Bangjin LIU, Sheng WAN, Jin WANG, Di XIAO, Jiasheng WU, Man CHEN, Yumin PENG, Yueli ZHOU, Cheng PENG, Min ZHANG, Bin WU, Linwei WANG, Qihua LIN, Xiaodong ZHENG, Zheng WENG, Shaohua ZHAO, Lunsen ZOU
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Patent number: 12158741Abstract: The present disclosure provides a self-adaptive test method for an intelligent prediction algorithm of analog measured values. Firstly, an event recording sequence, an analog measurement point ID and an analog measurement point alarm value are read from a time sequence event record table, an analog measurement point table and an alarm threshold table. Next, operation records of a normal operation state of a unit within a statistical cycle are acquired to form historical statistics of measured values of the analog measurement point based on switching value signals. Then, simulated measured values of the analog measurement point with time scales are calculated based on the historical statistics, the analog measurement point alarm value and an analog measurement point current measured value. Finally, sensitivity is calculated; and an alarm is sent to remind a technician to adjust the algorithm when the sensitivity is greater than a threshold.Type: GrantFiled: September 30, 2020Date of Patent: December 3, 2024Assignee: CSG POWER GENERATION CO., LTD.Inventors: Hao Zhang, Man Chen, Yu Gong, Yumin Peng, Xiong Dai, Mingxuan Yang, Xiaobo Qiu, Mingliang Yao, Yaxiong Yu, Jun She, Rufei He, Yanming Gao, Zhenglin Xiang, Jianqiu Li, Dehua Li, Xianbin Guo, Xiaoyi Wang
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Publication number: 20240388517Abstract: The present disclosure relates to method for cloud-edge data transmission of an electrochemical energy storage station, including: caching the first data to be transmitted and sending a connection re-establishment request to the cloud node; sending second data to be transmitted to the cloud node; sending the cached first data to the cloud node in an idle period after the first period; determining a characteristic value of third data to be transmitted, sending the characteristic value to the cloud node, and caching a non-characteristic value apart from the characteristic value, in a case where an abnormal working condition of the edge node is detected; sending to the cloud node fourth data to be transmitted; and sending the non-characteristic value of the third data to the cloud node in an idle period after the second period.Type: ApplicationFiled: October 6, 2023Publication date: November 21, 2024Applicant: CSG PGC ENERGY STORAGE RESEARCH INSTITUTEInventors: Hao ZHANG, Man CHEN, Yumin PENG, Yikai LI, Zengtao ZHAO, Fanqi HUANG, Peng PENG, Zhenkai HU, Wanzhou SUN, Jun SHE, Xiaoyi WANG
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Patent number: 12146881Abstract: The present invention provides a reagent composition for detection of a non-hematopoietic tumor and use thereof. Said reagent composition includes three sets of antibodies, with the first set of antibodies including an anti-CD9 antibody, an anti-GD2 antibody, an anti-CD3 antibody, an anti-CD4 antibody, an anti-CD56 antibody, an anti-CD36 antibody, an anti-CD81, and an anti-CD45 antibody; the second set of antibodies including an anti-HLA-ABC antibody, an anti-CD38 antibody, an anti-CD19 antibody, an anti-CD56 antibody, an anti-CD36 antibody, an anti-CD7 antibody, and an anti-CD45 antibody; the third set of antibodies including anti-cytoplasmic cytokeratin antibodies; wherein the first set of antibodies and the second set of antibodies are respectively used for samples in separate tubes, and the third set of antibodies is used for the sample in the same tube as the second set of antibodies.Type: GrantFiled: June 14, 2023Date of Patent: November 19, 2024Assignees: Synarc Research Laboratory (Beijing) Ltd., HEBEI YANDA LUDAOPEI HOSPITALInventors: Hui Wang, Man Chen, Aixian Wang, Meiwei Gong, Xueying Wu, Junyi Zhen, Qing Du, Ya Guo
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Patent number: 12060294Abstract: A manufacturing method of a large-outer-diameter quartz crucible for a Czochralski (CZ) single crystal is provided. The manufacturing method is a vacuum arc method, and specifically includes: releasing a high-temperature arc with an electrode bundle composed of 2N+1 electrodes to fuse a crucible blank, and performing rapid cooling to form an initial quartz crucible product, where N is an integer greater than or equal to 2; the 2N+1 electrodes include one central main electrode and 2N auxiliary electrodes; the 2N auxiliary electrodes are equidistantly distributed on a circumference with the central main electrode as a center; the central main electrode is aligned at an axis of the crucible mold; the 2N auxiliary electrodes are connected to two phases of an industrial three-phase power, and the two phases are alternately arranged on the auxiliary electrodes; the central main electrode is connected to a remaining phase of the industrial three-phase power.Type: GrantFiled: March 31, 2022Date of Patent: August 13, 2024Assignee: JINZHOU YOUXIN QUARTZ TECHNOLOGY CO., LTDInventors: Zonghui Li, Man Chen, Ye Wang, Zhen Wang, ZhiQiang Zhang, XingWang Sun, Li Ma
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Publication number: 20240262734Abstract: A manufacturing method of a large-outer-diameter quartz crucible for a Czochralski (CZ) single crystal is provided. The manufacturing method is a vacuum arc method, and specifically includes: releasing a high-temperature arc with an electrode bundle composed of 2N+1 electrodes to fuse a crucible blank, and performing rapid cooling to form an initial quartz crucible product, where N is an integer greater than or equal to 2; the 2N+1 electrodes include one central main electrode and 2N auxiliary electrodes; the 2N auxiliary electrodes are equidistantly distributed on a circumference with the central main electrode as a center; the central main electrode is aligned at an axis of the crucible mold; the 2N auxiliary electrodes are connected to two phases of an industrial three-phase power, and the two phases are alternately arranged on the auxiliary electrodes; the central main electrode is connected to a remaining phase of the industrial three-phase power.Type: ApplicationFiled: March 31, 2022Publication date: August 8, 2024Applicant: JINZHOU YOUXIN QUARTZ TECHNOLOGY CO., LTDInventors: Zonghui LI, Man CHEN, Ye WANG, Zhen WANG, ZhiQiang ZHANG, XingWang SUN, Li MA
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Publication number: 20240254030Abstract: A manufacturing method for high-quality quartz crucible uses a vacuum arc method to melt, the positioning of the graphite electrode and dwell time at each position meet following requirements in which: taking a position of an upper end surface of a mold opening as a zero point, an end of the graphite electrode is marked as + when above the zero point, marked as ? when below the zero point; a starting position of the graphite electrode is +0.10˜0.30 times an outer diameter of the crucible, dwell time ?2 minutes, then the position is descended sequentially in accordance with a stepwise positioning method, staying for a period of time every time descending to a position, the graphite electrode continuously releases a high-temperature arc to melt crucible blank during a corresponding period of time at a corresponding position, and reaches a bottom polishing position after moving at least 3 times.Type: ApplicationFiled: April 10, 2024Publication date: August 1, 2024Applicant: JINZHOU YOUXIN QUARTZ TECHNOLOGY CO., LTDInventors: Man CHEN, Zonghui LI, Jian ZHU, Ye WANG, Zhen WANG, Zhiqiang ZHANG
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Publication number: 20240209032Abstract: Embodiments of a recombinant Respiratory Syncytial Virus (RSV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the RSV F ectodomain trimer and methods of producing the RSV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the recombinant RSV F ectodomain trimer to the subject.Type: ApplicationFiled: January 10, 2024Publication date: June 27, 2024Applicant: The United State of America, as represented by the Secretary, Department of Health & Human ServicesInventors: Peter Kwong, Barney Graham, John Mascola, Li Ou, Aliaksandr Druz, Man Chen, Wing-Pui Kong, Ivelin Stefanov Georgiev, Emily Rundlet, Michael Gordon Joyce, Yaroslav Tsybovsky, Paul Thomas, Marie Pancera, Mallika Sastry, Cinque Soto, Joseph Van Galen, Guillaume Stewart-Jones, Yongping Yang, Baoshan Zhang, Ulrich Baxa
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Publication number: 20240201097Abstract: An optical detection device includes a detection workspace, a first image acquisition device, a second image acquisition device, a detection light source, and a conveyor. The detection workspace is configured to hold a target workpiece under detection. The first image acquisition device is configured to acquire an image of the target workpiece along a first direction. The second image acquisition device is configured to acquire an image of the target workpiece along a second direction different from the first direction. The detection light source is configured to provide detection light for the first image acquisition device and the second image acquisition device. The conveyor is configured to convey the target workpiece into or out of the detection workspace. An optical axis of at least a part of the detection light provided by the detection light source is coaxial with an optical axis of the first image acquisition device.Type: ApplicationFiled: November 29, 2023Publication date: June 20, 2024Inventors: Lin MA, Chao WU, Yunlong HUANG, Man CHEN
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Publication number: 20240192141Abstract: The present application discloses an appearance inspection device and an apparatus for manufacturing a battery cell. The appearance inspection device for inspecting a battery cell comprises: a first camera assembly comprising a first camera and a first light source, the first light source being configured to provide illumination to the first camera, and the first camera being configured to acquire images of a first surface of the battery cell when the first surface is covered by an insulating layer; and a second camera assembly comprising a second camera and a second light source, the second light source being configured to provide illumination to the second camera, and the second camera being configured to acquire images of the first surface when at least a partial region of the first surface is not covered by the insulating layer.Type: ApplicationFiled: March 28, 2023Publication date: June 13, 2024Inventors: Lin MA, Ming ZHANG, Yunlong HUANG, Man CHEN
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Patent number: 11981707Abstract: Disclosed are Respiratory Syncytial Virus (RSV) antigens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the antigens and methods of producing the antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject.Type: GrantFiled: September 11, 2023Date of Patent: May 14, 2024Assignee: The United States of America, as represented by the Secretary, Department of Health and Human ServicesInventors: Peter D. Kwong, Barney S. Graham, Jason S. McLellan, Jeffrey Boyington, Lei Chen, Man Chen, Gwo-Yu Chuang, Ivelin Stefanov Georgiev, Jason Gorman, Michael Gordon Joyce, Masaru Kanekiyo, Gilad Ofek, Marie Pancera, Mallika Sastry, Cinque Soto, Sanjay Srivatsan, Guillaume Stewart-Jones, Yongping Yang, Baoshan Zhang, Tongqing Zhou
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Patent number: 11972557Abstract: Provided are a vibration object monitoring method and apparatus, a computer device, and a storage medium. The method includes: in response to detecting that a vibration object exists in a monitoring video picture for a target monitoring region, a vibration object region in the monitoring video picture is determined, where the vibration object region is a region where the vibration object is located in the monitoring video picture; displacement information of a key point of the vibration object in the vibration object region is recorded; vibration information of the vibration object in the monitoring video picture is determined based on the displacement information; and a vibration object monitoring result for the target monitoring region is generated according to the vibration information. The abnormal vibration monitoring can be performed on the vibration object in the target monitoring region in time according to this method.Type: GrantFiled: March 8, 2021Date of Patent: April 30, 2024Assignee: CSG POWER GENERATION CO., LTD.Inventors: Yumin Peng, Zhiqiang Wang, Hao Zhang, Hengjun Chen, Xun Hu, Tuixiang Feng, Liqun Sun, Man Chen, Yong Lu, Tao Liu, Kai Lin, Yulin Han