Abstract: Embodiments of a recombinant Respiratory Syncytial Virus (RSV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the RSV F ectodomain trimer and methods of producing the RSV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the recombinant RSV F ectodomain trimer to the subject.

Abstract: Disclosed is a fully immersed energy storage device, which includes a casing and a water pump. An insulation box is mounted inside the casing, and the insulation box is assembled with an assembly plate thereon. A mounting platform is mounted on the assembly plate and assembled with an annular rack. A rotating groove is provided between the mounting platform and the annular rack. Balls are placed in the rotating groove. The mounting platform is assembled with an assembly block, on which a rotating shaft is mounted. One end of the rotating shaft connects to a gear. The other end of the rotating shaft connects to a first assembly rod, to which a second assembly rod is connected. The second assembly rod connects to a fixed block, which is connected to an energy storage box. A motor base is mounted on the casing. A motor is mounted on the motor base.

Abstract: The present disclosure provides a self-adaptive test method for an intelligent prediction algorithm of analog measured values. Firstly, an event recording sequence, an analog measurement point ID and an analog measurement point alarm value are read from a time sequence event record table, an analog measurement point table and an alarm threshold table. Next, operation records of a normal operation state of a unit within a statistical cycle are acquired to form historical statistics of measured values of the analog measurement point based on switching value signals. Then, simulated measured values of the analog measurement point with time scales are calculated based on the historical statistics, the analog measurement point alarm value and an analog measurement point current measured value. Finally, sensitivity is calculated; and an alarm is sent to remind a technician to adjust the algorithm when the sensitivity is greater than a threshold.

Abstract: The present disclosure relates to method for cloud-edge data transmission of an electrochemical energy storage station, including: caching the first data to be transmitted and sending a connection re-establishment request to the cloud node; sending second data to be transmitted to the cloud node; sending the cached first data to the cloud node in an idle period after the first period; determining a characteristic value of third data to be transmitted, sending the characteristic value to the cloud node, and caching a non-characteristic value apart from the characteristic value, in a case where an abnormal working condition of the edge node is detected; sending to the cloud node fourth data to be transmitted; and sending the non-characteristic value of the third data to the cloud node in an idle period after the second period.

Abstract: The present invention provides a reagent composition for detection of a non-hematopoietic tumor and use thereof. Said reagent composition includes three sets of antibodies, with the first set of antibodies including an anti-CD9 antibody, an anti-GD2 antibody, an anti-CD3 antibody, an anti-CD4 antibody, an anti-CD56 antibody, an anti-CD36 antibody, an anti-CD81, and an anti-CD45 antibody; the second set of antibodies including an anti-HLA-ABC antibody, an anti-CD38 antibody, an anti-CD19 antibody, an anti-CD56 antibody, an anti-CD36 antibody, an anti-CD7 antibody, and an anti-CD45 antibody; the third set of antibodies including anti-cytoplasmic cytokeratin antibodies; wherein the first set of antibodies and the second set of antibodies are respectively used for samples in separate tubes, and the third set of antibodies is used for the sample in the same tube as the second set of antibodies.

Abstract: A tire and a tire wear indicating structure thereof are disclosed. The tire wear indicating structure includes an indicator, at least three inclined portions of different heights, and at least two indicating grooves. The indicator has an indicator depth. The inclined portions are adjacently arranged to each other and located in the indicator. The heights of the inclined portions decrease progressively. The indicating grooves are disposed between the adjacent inclined portions. The indicating grooves each have an indicating groove depth that is the main groove depth minus 1.8 to 2.2 mm and is greater than the indicator depth. The current wear condition of the tire can be seen more intuitively, without too much information interfering with the judgment.

Abstract: A manufacturing method of a large-outer-diameter quartz crucible for a Czochralski (CZ) single crystal is provided. The manufacturing method is a vacuum arc method, and specifically includes: releasing a high-temperature arc with an electrode bundle composed of 2N+1 electrodes to fuse a crucible blank, and performing rapid cooling to form an initial quartz crucible product, where N is an integer greater than or equal to 2; the 2N+1 electrodes include one central main electrode and 2N auxiliary electrodes; the 2N auxiliary electrodes are equidistantly distributed on a circumference with the central main electrode as a center; the central main electrode is aligned at an axis of the crucible mold; the 2N auxiliary electrodes are connected to two phases of an industrial three-phase power, and the two phases are alternately arranged on the auxiliary electrodes; the central main electrode is connected to a remaining phase of the industrial three-phase power.

Abstract: A manufacturing method of a large-outer-diameter quartz crucible for a Czochralski (CZ) single crystal is provided. The manufacturing method is a vacuum arc method, and specifically includes: releasing a high-temperature arc with an electrode bundle composed of 2N+1 electrodes to fuse a crucible blank, and performing rapid cooling to form an initial quartz crucible product, where N is an integer greater than or equal to 2; the 2N+1 electrodes include one central main electrode and 2N auxiliary electrodes; the 2N auxiliary electrodes are equidistantly distributed on a circumference with the central main electrode as a center; the central main electrode is aligned at an axis of the crucible mold; the 2N auxiliary electrodes are connected to two phases of an industrial three-phase power, and the two phases are alternately arranged on the auxiliary electrodes; the central main electrode is connected to a remaining phase of the industrial three-phase power.

Abstract: A manufacturing method for high-quality quartz crucible uses a vacuum arc method to melt, the positioning of the graphite electrode and dwell time at each position meet following requirements in which: taking a position of an upper end surface of a mold opening as a zero point, an end of the graphite electrode is marked as + when above the zero point, marked as ? when below the zero point; a starting position of the graphite electrode is +0.10˜0.30 times an outer diameter of the crucible, dwell time ?2 minutes, then the position is descended sequentially in accordance with a stepwise positioning method, staying for a period of time every time descending to a position, the graphite electrode continuously releases a high-temperature arc to melt crucible blank during a corresponding period of time at a corresponding position, and reaches a bottom polishing position after moving at least 3 times.

Abstract: A tire and a tire wear indicating structure thereof are disclosed. The tire wear indicating structure includes an indicator, at least three inclined portions of different heights, and at least two indicating grooves. The indicator has an indicator depth. The inclined portions are adjacently arranged to each other and located in the indicator. The heights of the inclined portions decrease progressively. The indicating grooves are disposed between the adjacent inclined portions. The indicating grooves each have an indicating groove depth that is the main groove depth minus 1.8 to 2.2 mm and is greater than the indicator depth. The current wear condition of the tire can be seen more intuitively, without too much information interfering with the judgment.

Abstract: Embodiments of a recombinant Respiratory Syncytial Virus (RSV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the RSV F ectodomain trimer and methods of producing the RSV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the recombinant RSV F ectodomain trimer to the subject.

Abstract: An optical detection device includes a detection workspace, a first image acquisition device, a second image acquisition device, a detection light source, and a conveyor. The detection workspace is configured to hold a target workpiece under detection. The first image acquisition device is configured to acquire an image of the target workpiece along a first direction. The second image acquisition device is configured to acquire an image of the target workpiece along a second direction different from the first direction. The detection light source is configured to provide detection light for the first image acquisition device and the second image acquisition device. The conveyor is configured to convey the target workpiece into or out of the detection workspace. An optical axis of at least a part of the detection light provided by the detection light source is coaxial with an optical axis of the first image acquisition device.

Abstract: The present application discloses an appearance inspection device and an apparatus for manufacturing a battery cell. The appearance inspection device for inspecting a battery cell comprises: a first camera assembly comprising a first camera and a first light source, the first light source being configured to provide illumination to the first camera, and the first camera being configured to acquire images of a first surface of the battery cell when the first surface is covered by an insulating layer; and a second camera assembly comprising a second camera and a second light source, the second light source being configured to provide illumination to the second camera, and the second camera being configured to acquire images of the first surface when at least a partial region of the first surface is not covered by the insulating layer.

Abstract: Disclosed are Respiratory Syncytial Virus (RSV) antigens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the antigens and methods of producing the antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject.

Abstract: Provided are a vibration object monitoring method and apparatus, a computer device, and a storage medium. The method includes: in response to detecting that a vibration object exists in a monitoring video picture for a target monitoring region, a vibration object region in the monitoring video picture is determined, where the vibration object region is a region where the vibration object is located in the monitoring video picture; displacement information of a key point of the vibration object in the vibration object region is recorded; vibration information of the vibration object in the monitoring video picture is determined based on the displacement information; and a vibration object monitoring result for the target monitoring region is generated according to the vibration information. The abnormal vibration monitoring can be performed on the vibration object in the target monitoring region in time according to this method.

Abstract: The present invention provides a detection reagent and therapeutic target for B cell tumor after targeted therapy and related applications. The reagent composition comprises 3 groups of antibodies, with the first group of antibodies including an anti-CD38 antibody, an anti-CD10 antibody, an anti-CD34 antibody, an anti-CD19 antibody, an anti-CD24 an antibody, an anti-CD20 antibody, an anti-CD81 antibody, an anti-CD45 antibody; the second group of antibodies including an anti-CD38 antibody, an anti-CD10 antibody, an anti-CD34 antibody, an anti-CD19 antibody, an anti-CD20 antibody, an anti-CD72 antibody, an anti-CD45 antibody; and the third group of antibodies including an anti-cytoplasmic CD79a antibody. The reagent composition of the present invention can be applied for the detection of B-lymphocyte tumors after targeted therapy by flow cytometry.

Abstract: Disclosed are antigen binding polypeptides and antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural and/or functional features. Also disclosed are polynucleotides and vectors encoding such polypeptides and polypeptide complexes; host cells, pharmaceutical compositions and kits containing such polypeptides and polypeptide complexes; and methods of using such polypeptides and polypeptide complexes.

Abstract: Provided are a vibration object monitoring method and apparatus, a computer device, and a storage medium. The method includes: in response to detecting that a vibration object exists in a monitoring video picture for a target monitoring region, a vibration object region in the monitoring video picture is determined, where the vibration object region is a region where the vibration object is located in the monitoring video picture; displacement information of a key point of the vibration object in the vibration object region is recorded; vibration information of the vibration object in the monitoring video picture is determined based on the displacement information; and a vibration object monitoring result for the target monitoring region is generated according to the vibration information. The abnormal vibration monitoring can be performed on the vibration object in the target monitoring region in time according to this method.

Abstract: Embodiments of a recombinant Respiratory Syncytial Virus (RSV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the RSV F ectodomain trimer and methods of producing the RSV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the recombinant RSV F ectodomain trimer to the subject.

Abstract: Disclosed are Respiratory Syncytial Virus (RSV) antigens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the antigens and methods of producing the antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject.