Patents by Inventor Man Cheng

Man Cheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210285701
    Abstract: Embodiments of this disclosure provide a refrigerant distributor and an evaporator including the refrigerant distributor. The refrigerant distributor (4) includes: a box body (42); a refrigerant inlet (41) arranged on an upper surface (421) of the box body (42); liquid exit openings (46) evenly arranged on a lower surface (422) of the box body (42); and end plates arranged at both ends of the box body (42) in a length direction and enclosing the box body (42) from the two ends; wherein, in a height direction from the lower surface (422) of the box body (42) to the upper surface (421) and within a predetermined height range starting from the lower surface (422), a width of the box body (42) increases gradually; and a pre-distributor (3) is arranged inside the box body (42). The embodiments are advantageous to even distribution of the refrigerant, thereby improving heat exchange effect of the evaporator.
    Type: Application
    Filed: May 28, 2021
    Publication date: September 16, 2021
    Inventors: Man CHENG, Feng XU, Jie ZHOU, Xin MA, Xiong LUO
  • Patent number: 11021735
    Abstract: Methods of detecting and amplifying short RNAs are provided.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: June 1, 2021
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Man Cheng, Xiao-Song Gong, Yan Wang, Adam M. McCoy
  • Patent number: 10961518
    Abstract: Mutant Type-A DNA polymerases having increased resistance to one or more polymerization activity inhibitors are provided.
    Type: Grant
    Filed: January 15, 2019
    Date of Patent: March 30, 2021
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Xiangdong Meng, Man Cheng
  • Patent number: 10938310
    Abstract: A DC-DC power converter has an auxiliary tank cascaded to share an efficiency tank's inductor, capacitor, and transformer. Switching transistors pump the auxiliary tank at startup to provide a boost current. The switching frequency is reduced in steps and the voltage gain and power of the converter sensed until the voltage gain matches a voltage gain calculated for the efficiency tank. Then tank switchover occurs and transistors to the efficiency tank are pumped with the last switching frequency used by the auxiliary tank, and the auxiliary tank is not pumped. Since the voltage gains before and after tank switchover are equal, no output voltage deviation or current spike occurs. A voltage sag or failure switches back to the auxiliary tank at a switching frequency determined by a dynamic contour line where the voltage gains of the two tanks are equal for the current power state.
    Type: Grant
    Filed: January 2, 2020
    Date of Patent: March 2, 2021
    Assignee: Hong Kong Applied Science and Technology Research Institute Company, Limited
    Inventors: Chi Man Cheng, Shek Mong Wong, Tak Lok Shum
  • Publication number: 20200385791
    Abstract: Provided are methods for detecting the presence of multiple barcoded solid supports in partitions, the method comprising providing a plurality of partitions wherein at least some partitions comprises multiple solid supports, where each solid support is linked to different solid support oligonucleotides, the solid support oligonucleotides comprising a barcode unique for the solid support; synthesizing a complementary sequence of the oligonucleotides to produce a double-stranded polynucleotide having barcodes from two of the solid support oligonucleotides; and sequencing one or both strands of the double-stranded polynucleotides, wherein sequences comprising two different barcodes indicates the presence of two solid supports in the same partition. Also provided are compositions and methods for producing the oligonucleotides.
    Type: Application
    Filed: June 8, 2020
    Publication date: December 10, 2020
    Inventors: Ronald LEBOFSKY, Zachary BURKETT, Man CHENG, Meiye WU, Pranav PATEL, Duc DO, Arkadiusz BIBILLO
  • Patent number: 10862988
    Abstract: Methods and systems for operating a sensor network are provided. In one example, a server may provide graphical data representing a hierarchical sensor network for displaying at a client device. The server may receive a selection to display sensor data from a first node of the nodes of the hierarchical sensor network and determine, based on the selection, a hierarchical sensor label associated with one or more first sensors of the hierarchical sensor network corresponding to the first node. The server may also receive a plurality of messages including sensor data generated by a plurality of sensors of the hierarchical sensor network from an in-bound real-time message processor, and identify a first set of messages based on the hierarchical sensor label. The server may extract the sensor data from the first set of messages and provide the sensor data for displaying at the client device.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: December 8, 2020
    Assignee: The Chinese University of Hong Kong
    Inventors: Waiman Cheung, Sung-Chi Chu, Chun Yip Leung, Kwong Man Cheng
  • Patent number: 10803130
    Abstract: Systems, methods, and non-transitory computer-readable media can determine a profile model for a page that is accessible through the social networking system, the profile model describing one or more modal characteristics of users of the social networking system that have fanned the page. A determination can be made that the page should be recommended to a first user of the social networking system based at least in part on the profile model. At least one page recommendation that references the page can be provided to the first user.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: October 13, 2020
    Assignee: Facebook, Inc.
    Inventors: Bradley Ray Green, Betty Yee Man Cheng, Jinyi Yao
  • Patent number: 10787694
    Abstract: The present invention provides methods and compositions for improving the efficiency of nucleic acid amplification reactions. The invention encompasses hybrid polymerases that show increased processivity over wild type polymerases as well as decreased exonucleases activity. The invention also encompasses methods, compositions and kits for conducting nucleic acid synthesis and amplification reactions in which non-specific amplification of primers is reduced.
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: September 29, 2020
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Xiao-Song Gong, John Sullivan, Rongdian Fu, Yan Wang, Evan H. Bursey, Man Cheng
  • Patent number: 10772141
    Abstract: Methods and systems for peer-to-peer communication are provided. In one example, a first device may receive, from a server, a pairing code and a first handshake code. The first device may transmit at least a first portion of the pairing code in a first broadcast message and receive, from the second device, a second broadcast message. The first device may authenticate the second device based on at least a second portion of the pairing code in the second broadcast message. The first device may establish a wireless peer-to-peer communication channel with the second device, and receive, from the second device, a second handshake code via the wireless peer-to-peer communication channel. The first device may authorize the second party to engage in an offline interaction with the first party based on the first handshake code and the second handshake code.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: September 8, 2020
    Assignee: The Chinese University of Hong Kong
    Inventors: Waiman Cheung, Sung-Chi Chu, Chun Yip Leung, Kwong Man Cheng, Pan Kwok
  • Publication number: 20200056231
    Abstract: Comparison of common sequencing reads from sequencing based on partition-based barcoding can be used to improve sequencing results. Increased loading of barcodes per partition can also improve sequencing results.
    Type: Application
    Filed: August 20, 2019
    Publication date: February 20, 2020
    Inventors: Ronald LEBOFSKY, Andrew KOHLWAY, Jennifer CHEW, Zachary BURKETT, Man CHENG
  • Publication number: 20200008251
    Abstract: Methods and systems for peer-to-peer communication are provided. In one example, a first device may receive, from a server, a pairing code and a first handshake code. The first device may transmit at least a first portion of the pairing code in a first broadcast message and receive, from the second device, a second broadcast message. The first device may authenticate the second device based on at least a second portion of the pairing code in the second broadcast message. The first device may establish a wireless peer-to-peer communication channel with the second device, and receive, from the second device, a second handshake code via the wireless peer-to-peer communication channel. The first device may authorize the second party to engage in an offline interaction with the first party based on the first handshake code and the second handshake code.
    Type: Application
    Filed: June 28, 2018
    Publication date: January 2, 2020
    Inventors: Waiman Cheung, Sung-Chi Chu, Chun Yip Leung, Kwong Man Cheng, Pan Kwok
  • Publication number: 20190387866
    Abstract: This invention provides a backpack, comprising a backpack body and straps mounted on a back part of the backpack body, a main pocket-mouth and a zipper for opening and closing the main pocket-mouth are arranged between a front part and the back part of the backpack body; a first handle and a second handle are arranged on the front part and the back part of the backpack body respectively, the first handle and the second handle are connected to each other through a VELCRO hook-and-loop fastener or a belt buckle; the plurality of straps comprise a first strap that faces away from shoulders of a human body and a second strap that adjusts the overall length of the straps. The backpack of the present application has the advantages of light weight, neat appearance, good appearance, and anti-theft function, which keep the backpack's functionality and fashion in the best balance.
    Type: Application
    Filed: June 22, 2018
    Publication date: December 26, 2019
    Inventor: Kwun Man Cheng
  • Publication number: 20190225951
    Abstract: Mutant Type-A DNA polymerases having increased resistance to one or more polymerization activity inhibitors are provided.
    Type: Application
    Filed: January 15, 2019
    Publication date: July 25, 2019
    Inventors: Xiangdong MENG, Man CHENG
  • Patent number: 10351831
    Abstract: Fusion polypeptides having a heterologous 5?-3? exonuclease domain linked to a polymerase that does not naturally have 5?-3? exonuclease activity, as well as methods of their use are provided. Other aspects are also disclosed.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: July 16, 2019
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Yan Wang, Man Cheng
  • Publication number: 20190190999
    Abstract: Methods and systems for operating a sensor network are provided. In one example, a server may provide graphical data representing a hierarchical sensor network for displaying at a client device. The server may receive a selection to display sensor data from a first node of the nodes of the hierarchical sensor network and determine, based on the selection, a hierarchical sensor label associated with one or more first sensors of the hierarchical sensor network corresponding to the first node. The server may also receive a plurality of messages including sensor data generated by a plurality of sensors of the hierarchical sensor network from an in-bound real-time message processor, and identify a first set of messages based on the hierarchical sensor label. The server may extract the sensor data from the first set of messages and provide the sensor data for displaying at the client device.
    Type: Application
    Filed: December 18, 2017
    Publication date: June 20, 2019
    Inventors: Waiman Cheung, Sung-Chi Chu, Chun Yip Leung, Kwong Man Cheng
  • Patent number: 10287620
    Abstract: Methods of determining polymerase fidelity are provided. In one embodiment, the method comprises filling a gapped plasmid with a polymerase to form a gap-filled plasmid, wherein the gap-filled plasmid comprises a gene encoding an protein that is functional or non-functional depending on the polymerase fidelity; forming a plurality of partitions from a solution comprising the gap-filled plasmid and a label for detecting the presence of the plasmid; detecting the presence of the gap-filled plasmid in one or more of the partitions; and determining the fidelity of the polymerase by determining a ratio of partitions containing the gene encoding a functional protein to partitions containing a gene encoding a non-functional protein.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: May 14, 2019
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Man Cheng, Xiangdong Meng, Jan Zur Megede
  • Publication number: 20180349796
    Abstract: The present disclosure relates to techniques for data classification. The techniques for data classification may include a machine learning (ML)-based classifier for classification of potentially objectionable content and differentiating responses based on a confidence score and classification category outputted by the ML-based classifier.
    Type: Application
    Filed: June 2, 2017
    Publication date: December 6, 2018
    Inventors: Tanton Holt Gibbs, Li-yen Chen, Robert Charles Boyle, Betty Yee Man Cheng
  • Publication number: 20180305739
    Abstract: Methods of detecting and amplifying short RNAs are provided.
    Type: Application
    Filed: June 15, 2018
    Publication date: October 25, 2018
    Inventors: Man Cheng, Xiao-Song Gong, Yan Wang, Adam M. McCoy
  • Publication number: 20180271960
    Abstract: One example embodiment is a method of treating lung carcinoma in a subject in need thereof. The method includes administering to the subject a therapeutically effective amount of an arginine reducing compound and a therapeutically effective amount of an ornithine decarboxylase (ODC) inhibitor to provide a combination therapy that has a synergistic therapeutic effect compared to an effect of the arginine reducing compound and an effect of the ODC inhibitor, in which each of the arginine reducing compound and the ODC inhibitor is administered alone.
    Type: Application
    Filed: September 21, 2016
    Publication date: September 27, 2018
    Inventors: Ning Man CHENG, Kin Pong U, Sze Kwan LAM, Chung Man HO
  • Publication number: 20180258455
    Abstract: The present invention provides methods and compositions for improving the efficiency of nucleic acid amplification reactions. The invention encompasses hybrid polymerases that show increased processivity over wild type polymerases as well as decreased exonucleases activity. The invention also encompasses methods, compositions and kits for conducting nucleic acid synthesis and amplification reactions in which non-specific amplification of primers is reduced.
    Type: Application
    Filed: May 11, 2018
    Publication date: September 13, 2018
    Inventors: Xiao-Song GONG, John SULLIVAN, Rongdian FU, Yan WANG, Evan H. BURSEY, Man CHENG