Abstract: Methods of detecting and amplifying short RNAs are provided.

Abstract: Systems, methods, and computer-readable storage media are provided for permitting users to search the content of a plurality of apps from a single search query input location. A user inputs a search query and a plurality of apps and/or the content thereof is searched to determine relevancy to the input query. If an app having relevant app content is identified, it may be determined if the app is associated with the querying user. If it is determined that the app is associated with the querying user, the information determined relevant to the input query may be presented to the user. If, it is determined that the app is not associated with the user, the user may be presented with the identity of the app and/or be directed to a location (e.g., an app store) where the user can become associated with the identified app and obtain the desired information.

Abstract: Liquid storage solutions comprising polymerases are provided.

Abstract: The present invention provides methods and compositions for improving the efficiency of nucleic acid amplification reactions. The invention encompasses hybrid polymerases that show increased processivity over wild type polymerases as well as decreased exonucleases activity. The invention also encompasses methods, compositions and kits for conducting nucleic acid synthesis and amplification reactions in which non-specific amplification of primers is reduced.

Abstract: Fusion polypeptides having a heterologous 5?-3? exonuclease domain linked to a polymerase that does not naturally have 5?-3? exonuclease activity, as well as methods of their use are provided. Other aspects are also disclosed.

Abstract: Methods and compositions for in situ detection of circular RNA in a tissue sample are provided.

Abstract: Fusion polypeptides having a heterologous 5?-3? exonuclease domain linked to a polymerase that does not naturally have 5?-3? exonuclease activity, as well as methods of their use are provided. Other aspects are also disclosed.

Abstract: Methods of determining polymerase fidelity are provided. In one embodiment, the method comprises filling a gapped plasmid with a polymerase to form a gap-filled plasmid, wherein the gap-filled plasmid comprises a gene encoding an protein that is functional or non-functional depending on the polymerase fidelity; forming a plurality of partitions from a solution comprising the gap-filled plasmid and a label for detecting the presence of the plasmid; detecting the presence of the gap-filled plasmid in one or more of the partitions; and determining the fidelity of the polymerase by determining a ratio of partitions containing the gene encoding a functional protein to partitions containing a gene encoding a non-functional protein.

Abstract: Systems, methods, and non-transitory computer-readable media can determine a profile model for a page that is accessible through the social networking system, the profile model describing one or more modal characteristics of users of the social networking system that have fanned the page. A determination can be made that the page should be recommended to a first user of the social networking system based at least in part on the profile model. At least one page recommendation that references the page can be provided to the first user.

Abstract: The present invention provides methods for improving the specificity of nucleic acid amplification comprising incubating a nucleic acid molecule with a polymerase-Sso7 DNA binding domain conjugate and arginine, spermidine, or spermine. The present invention also provides reaction mixtures and kits for improving the specificity of nucleic acid amplification.

Abstract: The present invention provides methods for determining whether two or more nucleic acid molecules or two or more regions of a nucleic acid molecule in a sample are in close proximity to each other due to direct or indirect physical interactions.

Abstract: Liquid storage solutions comprising polymerases are provided.

Abstract: Improved Sso7-polymerase conjugate proteins are provided.

Abstract: Methods of detecting and amplifying short RNAs are provided.

Abstract: The present invention provides a site-directed mutated arginase and the preparation method thereof, and the use of said site-directed mutated arginase in preparing a medicament for treating an arginase-related disease. The present invention also provides a pegylated arginase and the preparation method thereof, and the use of said pegylated arginase in preparing a medicament for treating an arginase-related disease.

Abstract: Fusion polypeptides having a heterologous 5?-3? exonuclease domain linked to a polymerase that does not naturally have 5?-3? exonuclease activity, as well as methods of their use are provided. Other aspects are also disclosed.

Abstract: A carbonated beverage container includes a bottle having a flexible sidewall of generally circular cross section, a cap for closing a top opening of the bottle, pairs of coupling elements provided on diametrically opposite portions of the sidewall respectively and configured to be pushed towards each other and couple together, thereby partially collapsing the bottle and expelling a predetermined amount of air therefrom. A method of preserving the taste of carbonated beverage in a container is also disclosed.

Abstract: The present invention provides methods for improving the specificity of nucleic acid amplification comprising incubating a nucleic acid molecule with a polymerase-Sso7 DNA binding domain conjugate and arginine, spermidine, or spermine. The present invention also provides reaction mixtures and kits for improving the specificity of nucleic acid amplification.

Abstract: The present invention provides a site-directed mutated arginase and the preparation method thereof, and the use of said site-directed mutated arginase in preparing a medicament for treating an arginase-related disease. The present invention also provides a site-directed pegylated arginase and the preparation method thereof, and the use of said pegylated arginase in preparing a medicament for treating an arginase-related disease.

Abstract: The present invention provides methods and compositions for improving the efficiency of nucleic acid amplification reactions. The invention encompasses hybrid polymerases that show increased processivity over wild type polymerases as well as decreased exonucleases activity. The invention also encompasses methods, compositions and kits for conducting nucleic acid synthesis and amplification reactions in which non-specific amplification of primers is reduced.