Abstract: Combating mycoses in humans and other animals with hydroxyalkyl-azolyl derivatives of the formula ##STR1## in which R stands for hydrogen, alkyl or acyl,R.sup.1 stands for halogen, optionally substituted phenyl or the --Z--R.sup.3 grouping,R.sup.2 stands for optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted naphthyl, for the radical of the formula ##STR2## or for the radical of the formula ##STR3## X stands for nitrogen or a CH group and Y stands for the --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH--, --C.tbd.C--, ##STR4## groupings, whereinR.sup.5, R.sup.6, R.sup.7 and R.sup.8 independently of one another stand for hydrogen or alkyl having 1 to 4 carbon atoms,and their acid addition salts.

Abstract: Nikkomycin derivatives have been found to be orally or parenterally effective as anti-fungals in animals. They may be used alone or, preferably, in combination with azole antimycotics for a synergistic anti-fungal effect.

Abstract: A method of combating mycoses which comprises administering to a patient in need thereof an antimycotic effective amount of an azolylcyclopropyl-azolylmethyl-carbinol derivative of the formula ##STR1## in which Ar is optionally substituted aryl or optionally substituted heteroaryl,R is hydrogen, alkyl, alkenyl, alkinyl, trialkylsilyl, optionally substituted phenylalkyl or the acyl radical,X is a nitrogen atom or the CH group, andY is a nitrogen atom or the CH group,or an acid addition salt thereof.

Abstract: A method of combating mycoses in a patient in need thereof which comprises administering to such patient an antimycotically effective amount of a triazolylalkanol of the formula ##STR1## in which Ar stands for optionally substituted aryl andX stands for one of the groups --CH.sub.2 --; --O--CH.sub.2 --; --S--CH.sub.2 --; --CH.sub.2 --CH.sub.2 --; --CH.dbd.CH-- or --C.tbd.C--,or a physiologically tolerable acid addition salt thereof.

Abstract: The invention provides substituted 1,3-diazolyl-2-propanols defined herein generically by formula (I), useful as antimycotic agents. Also included in the invention are methods for the procurement of said substituted 1,3-diazolyl-2-propanols, compositions containing said antimycotic compounds and methods for the use of said compounds and compositions for treatment of mycoses.

Abstract: The invention relates to substituted hydroxyalkylazoles defined herein by formula (I), which compounds are useful as antimycotic agents. Also included in the invention are compositions containing said compounds and methods for the use of said compounds and compositions. In addition, the invention includes methods for the manufacture of the compounds of formula (I).

Abstract: The invention relates to 1-hydroxylethyl-azole derivatives of formula (I) in composition form and includes the use of such compositions as antimicrobial agents.

Abstract: A method of combating mycoses which comprises administering to a patient an antimycotically effective amount of a hydroxyethyl-azole of the formula ##STR1## in which R.sup.1 represents alkyl or the grouping Ar--Y--,Ar represents optionally substituted aryl,Y represents a direct bond or the groupings --CH.sub.2 --, --CH.sub.2 --CH.sub.2 --, --OCH.sub.2 --, --SCH.sub.2 --, --CH.dbd.CH-- or --C.dbd.C--,X represents a nitrogen atom or the CH group,Z represents oxygen or the NOR.sup.2 group andR.sup.2 represents hydrogen, alkyl, alkenyl, alkinyl, optionally substituted aralkyl or optionally substituted cycloalkylalkyl, or an acid addition salt thereof.

Abstract: An antimycotic agent, comprising a compound of the formula ##STR1## in which R.sup.1 is hydrogen, alkyl, optionally substituted phenyl or optionally substituted benzyl,R.sup.2 is hydrogen, alkyl, alkenyl, alkynyl, optionally substituted phenyl or optionally substituted benzyl,R.sup.3 and Y each independently is halogen, alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenoxyalkyl,R.sup.4 and R.sup.5 each independently is alkyl,X is a nitrogen atom or the CH group,m is 0, 1, 2 or 3,n is 1 or 2, andp is 0, 1 or 2,or an acid addition salt thereof.

Abstract: A process for the preparation of optically active azolylcarbinol derivatives having antimycotic fungicidal and plant growth regulating properties from racemic mixtures thereof. The (-)-enantiomer of 2-(4-chloro-phenoxymethyl)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)-2-butanol of the formula ##STR1## is prepared.

Abstract: Fibers and filaments of synthetic polymers containing from 0.1 to 5%, by weight, based on polymer, of an azole compound corresponding to the following general formula: ##STR1## and from 0.1 to 5%, by weight, based on polymer, of a dihydroxydiphenylmethane derivative corresponding to the following general formula: ##STR2## wherein n represents 0 or 1;m represents 0, 1 or 2;R.sub.1 represents halogen, halophenyl or phenyl;R.sub.2 represents --CO--C(CH.sub.3).sub.3 or --CHOH--C(CH.sub.3).sub.3 ; andR.sub.3 and R.sub.4 represent halogen,show laundry-stable, antimicrobial activity.

Abstract: The invention relates to hydroxyethylazolyl derivatives, defined herein by formula (I) and particularly to the use of said derivatives for the treatment of viral infections.

Abstract: The invention relates to 1-hydroxylethyl-azole derivatives of formula (I) in composition form and includes the use of such compositions as antimicrobial agents.

Abstract: The invention concerns the provision of compound of Formula I as defined herein as well as compositions containing compound of Formula I. Said compounds and compositions are used as antimycotic agents and the invention includes such use.

Abstract: The invention relates to bis-azolyl-substituted t-butanol derivatives defined herein under formula (I) and their use as antimycotic agents. Included in the invention are compositions containing said t-butanol derivatives and methods for using said derivatives and compositions containing them for their antimycotic activity.

Abstract: The invention relates to antimycotic compositions comprising (1) an antimycotic effective amount of an azole derivative having antimycotic activity, said azole derivative being in the form of particles less than 4.mu. in size, (2) an acid and/or a buffer system consisting of an organic acid and a salt thereof to provide a pH of 3 to 4 or less in aqueous solution and (3) an inert pharmaceutical carrier. Also included in the invention are methods for the short term treatment of vaginal infections utilizing the compositions of the invention.

Abstract: The invention relates to a process for production of tampons containing novel formulations of antimycotic azole derivatives which provide a higher release of active compounds and make short-term therapy possible. The tampon formulations of the invention contain active antimycotic azole derivatives in impregnated form, only melting at body temperature, or dissolved form, such as, for example, in suppository bases or their combinations with emulsifiers and/or spreading agents and/or solubilisers.

Abstract: The invention relates to 2-(4-chlorophenoxymethyl)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)-2-butanol and its use for treating herpes viral infections.

Abstract: The invention relates to the provision of antibacterial compositions and medicaments (as well as methods for their use as antibacterials) containing as an active compound an imidazolylenol ether of Formula (I) as defined hereinbelow.

Abstract: The invention relates to azolyl-phenoxy-tetrahydrofuran-2-ylidene-methanes defined herein under formula (I). Also included in the invention are compositions containing said compounds of formula (I) and methods for the use of such compounds and compositions as antimycotic agents. The invention further includes methods for the manufacture of the compounds of formula (I).