Abstract: Methods for selecting a filter for a filtration process are described. Input data is received, and based on the input data, one or more filter characteristics for each of a plurality of filter candidates for a filtration process are identified. Process parameters of the filtration process are identified. A computer-implemented simulation process of the filtration process for each of the plurality of filter candidates is performed, based on the identified process parameters and identified filter characteristics. One or more output characteristics of the filtration process are determined based on the simulation. A filter candidate of the plurality of filter candidates is selected based on the one or more output characteristics.

Abstract: A method includes first determining among a plurality of cells a first set of cells that are anomalous, second determining among remaining cells a second set of cells that are anomalous, and identifying a resulting set of anomalous cells being a combination of the first set and the second set of anomalous cells. The first determining is based on input data of a plurality of first features of each cell among the plurality of cells, and a first machine learning operation. The second determining is based on the input data of the plurality of first features of each cell among the remaining cells, and a second machine learning operation different from the first machine learning operation.

Abstract: An information management system implements a method for determining whether to initiate a failover of a storage manager in the system. Nodes in the system may be assigned as monitoring nodes configured to communicate with a storage manager. Furthermore, each monitoring node may be configured to transmit a status inquiry message to each other monitoring node, and each monitoring node may receive a status inquiry message from each other monitoring node. Each monitoring node may also generate a session message comprising status information, and a plurality of failover nodes may receive the generated session messages. A failover node may then determine whether a failover condition has occurred by applying a plurality of failover rules to the status information of the transmitted session message. Where the failover node determines that a failover condition has occurred, the failover node may activate another storage manager to take place of the presently assigned storage manager.

Abstract: Systems and methods are provided for medical image classification of images from varying sources. A set of microscopic medical images are acquired, and a first neural network module configured to reduce each of the set of microscopic medical images to a feature representation is generated. The first neural network module, a second neural network module, and a third neural network module are trained on at least a subset of the set of microscopic medical images. The second neural network module is trained to receive feature representation associated with an image of the microscopic images and classify the image into one of a first plurality of output classes. The third neural network module is trained to receive the feature representation, classify the image into one of a second plurality of output classes based on the feature representation, and provide feedback to the first neural network module.

Abstract: A cartridge assembly for a surgical stapling device includes a staple cartridge that includes a staple array that has a configuration to minimize blood leakage through a staple line formed by the staple cartridge.

Abstract: Described in detail herein are systems and methods for single instancing blocks of data in a data storage system. For example, the data storage system may include multiple computing devices (e.g., client computing devices) that store primary data. The data storage system may also include a secondary storage computing device, a single instance database, and one or more storage devices that store copies of the primary data (e.g., secondary copies, tertiary copies, etc.). The secondary storage computing device receives blocks of data from the computing devices and accesses the single instance database to determine whether the blocks of data are unique (meaning that no instances of the blocks of data are stored on the storage devices). If a block of data is unique, the single instance database stores it on a storage device. If not, the secondary storage computing device can avoid storing the block of data on the storage devices.

Abstract: The invention provides compounds having STimulator of INterferon Genes (STING) agonistic bioactivity that can be used in the treatment of tumors in patients afflicted therewith. The compounds are of formula (I): as defined herein. Compounds for practice of a method of the invention can be delivered via oral delivery for systemic exposure, as well as delivered intratumorally. Antitumor therapy using a compound of formula (I) can further comprise administration of an effective dose of an immune-checkpoint targeting drug.

Abstract: A method in which an enterprise switches its devices to various federated network slices across operators based on cost, time, quality, and/or availability parameters defined in flexible rules managed by the enterprise. The method includes obtaining, by a controller of an enterprise, one or more parameters of a device served by a network slice of a core network. The method further includes, based on the one or more parameters of the device and one or more rules, determining, by the controller, whether a triggering event associated with a slice reselection occurred and based on the triggering event and the one or more rules, selecting, by the controller, a federated network slice from among a plurality of network slices provided by a plurality of core networks. The method further includes the controller causing the device to switch from the network slice to the federated network slice.

Abstract: Systems and methods of providing usage-based maintenance services for a plurality of vehicles arranged in a fleet includes receiving usage data. A usage parameter distribution is generated, and a fleet usage model is generated according to the distribution. The fleet usage model expresses a score as a function of the usage parameter. Also, a score distribution is generated, and a reward model is generated according to the score distribution. The reward model expresses a maintenance reward as a function of the score. Additionally, the score for one of the vehicles is determined using the fleet usage model, and the maintenance reward is determined for the vehicle using the reward model.

Abstract: Disclosed herein are compounds of formula I: or a pharmaceutically acceptable salt thereof, where the variables are as defined herein. These compounds are useful in treating RET associated cancers. Formulations containing the compounds of formula I and methods of making the compounds of formula I are also disclosed.

Abstract: Generating a composite screenshot including contextually relevant screenshots and displayed information. The composite screenshot includes one or more screenshots captured from a display screen of a requesting user. Contextual relevance is determined according to collected user communications data such as IoT interactions, social media posts, and chat session transcripts.

Abstract: An exhaust device (108) for a vehicle is provided. The exhaust device (108) includes an outer shell (202), an inlet (206) to receive exhaust gases, an outlet (208), an inner shell (204) received within the outer shell (202), a pair of partition walls (216) and a Helmholtz neck (220). The inner shell (204) defines an inner volume (210). A plurality of first circumferential openings (212) extending through the inner shell (204) fluidly communicates the inlet (206) with the inner volume (210). A plurality of second circumferential openings (214) extending through the inner shell (204) fluidly communicates the outlet (208) with the inner volume (210). The pair of partition walls (216) is disposed between the inner shell (204) and the outer shell (202). The pair of partition walls (216), the inner shell (204) and the outer shell (202) define a Helmholtz chamber (218) therebetween. The partition walls (216) seal the Helmholtz chamber (218) from the inlet (206) and the outlet (208).

Abstract: The present disclosure is directed to techniques for streamlining the process of configuring IoT devices during their onboarding to a network by eliminating the need for pre-provisioning IoT devices with zero-touch deployment (ZTD) specific configurations during manufacturing. In one aspect, a method includes receiving, from an IoT device connected to a ZTD service, a message for establishing a connection to the ZTD service; provisioning, at the zero-touch deployment service, the IoT device with ZTD specific configurations; and completing, at the zero-touch deployment service, initial bootstrapping of the IoT device to establish the connection to the ZTD service using the ZTD specific configurations.

Abstract: Techniques that provide link auto-negotiation between a radio equipment controller (REC) and a radio equipment (RE) are described herein. In one embodiment, a method includes performing, by a proxy master, a Common Public Radio Interface (CPRI) Layer 1 (L1) link auto-negotiation with a RE to achieve a L1 synchronization between the proxy master and the RE at a link bit rate; communicating the link bit rate from the proxy master to a proxy slave; performing, by the proxy slave, a CPRI L1 link auto-negotiation with a REC to determine whether a L1 synchronization between the proxy slave and the REC is achieved, wherein if the L1 synchronization is achieved, the link bit rate is a common matching link bit rate achieved; and upon the common matching link bit rate being achieved, establishing a CPRI link between the REC and the RE using the common matching link bit rate.

Abstract: The present disclosure provides system and method for object detection in a discontinuous space. The system receives at least one captured image from one or more computing devices associated with one or more users. The at least one captured image comprises one or more objects in the discontinuous space, and the one or more objects are associated with at least one attribute. The system computes a score corresponding to each of at least one attribute of the one or more objects. The system detects the one or more objects in the discontinuous space based on the computed score. Further, the system determines a similarity grade for the one or more detected objects, where the similarity grade corresponds to an accuracy of inference for the one or more detected objects. Finally, the system updates a database based on the accuracy of inference to facilitate object detection in the discontinuous space.

Abstract: The present invention provides a robust and effective solution to an entity or an organization by enabling the entity to implement a system for that links together a wide variety of media processing systems to complete complex workflows. The system can be configured to read files in one format, process the files, and export the files in another. The system can be a cross-platform and can be easily ported to various operating systems and can be used to integrate privacy preserving components into the system.

Abstract: Robotic system and methods for robotic arthroplasty are provided. The robotic system includes a machining system and a guidance system. The guidance station tracks movement of one or more of various objects in the operating room, such as a surgical tool, a tibia of a patient, a talus of the patient, or a component of an implant. The guidance system tracks these objects for purposes of displaying their relative positions and orientations to the surgeon and, in some cases, for purposes of controlling movement of the surgical tool of the machining system relative to virtual cutting boundaries or other virtual objects associated with the tibia and talus to facilitate preparation of bone to receive an ankle implant system.

Abstract: An improved content indexing (CI) system is disclosed herein. For example, the improved CI system may include a distributed architecture of client computing devices, media agents, a single backup and CI database, and a pool of servers. After a file backup occurs, the backup and CI database may include file metadata indices and other information associated with backed up files. Servers in the pool of servers may, in parallel, query the backup and CI database for a list of files assigned to the respective server that have not been content indexed. The servers may then request a media agent to restore the assigned files from secondary storage and provide the restored files to the servers. The servers may then content index the received restored files. Once the content indexing is complete, the servers can send the content index information to the backup and CI database for storage.

Abstract: An integral geogrid includes a plurality of interconnected, oriented strands having an array of openings therein that is produced from a coextruded multilayer polymer sheet starting material. By virtue of the construction, the coextruded multilayer sheet components provide a crystalline synergistic effect during extrusion and orientation of the integral geogrid, resulting in enhanced material properties that provide performance benefits to use of the integral geogrid in soil geosyuthetic reinforcement.

Abstract: The present disclosure is directed to techniques for bootstrapping and certificate management of Internet of Things (IoT) devices using a zero-touch deployment (ZTD) service. In one aspect, a method of managing Internet of Thing (IoT) devices includes receiving, at an IoT management component, a bootstrapping request from an IoT device, the request including location information of the IoT device; receiving, from a controller, credential information for the IoT device; generating a policy for bootstrapping the IoT device based at least on the location information and the credential information; and sending the policy to the IoT device for the IoT device to complete the bootstrapping.