Abstract: A hydrocarbon isomerization system for an iC4 feed stream that provides for removal of C3s from an isomerization reactor feed stream by the addition of a depropanizer column to remove C3s from the reactor effluent stream after it has passed through a stabilizer column. This configuration prevents a buildup of C3s in the system and provides significant savings by reducing the size of the chloride treaters that are used to remove chlorides from off gas, increasing chlorides recovered to the hydrocarbon feed stream for use in combination with the isomerization catalyst. Significant utility savings are provided as well as a reduction in the amount of perchloroethane (PERC) and adsorbent that are required.

Abstract: A learning-based model is trained using a plurality of attributes of media. Depth estimation is performed using the learning-based model. The depth estimation supports performing a computer vision task on the media. Attributes used in the depth estimation include scene understanding, depth correctness, and processing of sharp edges and gaps. The media may be processed to perform media restoration or the media quality enhancement. A computer vision task may include semantic segmentation.

Abstract: An interferometer system including: an optical system arranged to split a radiation beam from a laser source into a first beam along a first optical path and a second beam along a second optical path, and recombine the first beam and the second beam to a recombined beam, a detector to receive the recombined beam and to provide a detector signal based on the received recombined beam, and a processing unit, wherein a first optical path length of the first optical path and a second optical path length of the second optical path have an optical path length difference, and wherein the processing unit is arranged to determine a mode hop of the laser source on the basis of a phase shift in the detector signal.

Abstract: Systems and methods are provided for fully automated screening for aneuploidy in a human embryo. An image of the embryo is obtained at an associated imager and provided to a neural network to generate a first clinical parameter. A set of at least one parameter representing one of biometric parameters of one of a patient receiving the embryo, an egg utilized to produce the human embryo, a sperm used to create the embryo, a sperm donor who provided sperm used to create the embryo, and an egg donor who provided the egg is retrieved, and a second clinical parameter is generated from the set of at least one parameter at a predictive model. A composite parameter, representing a likelihood of aneuploidy in the embryo, is generated from the first clinical parameter and the second clinical parameter.

Abstract: Systems and methods are provided for determining a clinical parameter representing the location of interest within a reproductive cellular structure. An image of the reproductive cellular structure is obtained and provided to a neural network to generate the clinical parameter. The clinical parameter is stored on a non-transitory computer readable medium.

Abstract: An improved information management system that implements a staging area or cache to temporarily store primary data in a native format before the primary data is converted into secondary copies in a secondary format is described herein. For example, the improved information management system can include various media agents that each include one or more high speed drives. When a client computing device provides primary data for conversion into secondary copies, the primary data can initially be stored in the native format in the high speed drive(s). If the client computing device then submits a request for the primary data, the media agent can simply retrieve the primary data from the high speed drive(s) and transmit the primary data to the client computing device. Because the primary data is already in the native format, no conversion operations are performed by the media agent, thereby reducing the restore delay.

Abstract: The primary object of the present invention is to provide a polymer synthase gene which is derived from mangrove soil metagenome, and the method for producing the useful copolymer by using this polymer synthase. Another object of the present invention is to provide an enoyl-CoA hydratase gene which is derived from Streptomyces sp. CFMR 7, and the method for producing the useful copolymer, P(3HB-co-3HHx) with increasing the composition of 3HHx by the expression of this enoyl-CoA hydratase. In order to achieve these objects, an isolated polynucleotide encoding for a polypeptide with polymer synthase activity comprising an amino acid sequence set forth in SEQ ID NO: 1 or 3, or an amino acid sequence set forth in SEQ ID NO: 1 or 3 wherein one or more amino acids is replaced, deleted or added are provided.

Abstract: Provided herein are RET kinase inhibitors according to the formula: pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods for their use in the treatment of diseases that can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders. A, R1, n, X1, X2, X3, X4, and R2 have the meanings given in the specification.

Abstract: Techniques disclosed herein are well suited to restoring deduplicated backup data from cloud-based storage and from multi-node replicated files systems, and they also improve performance in more traditional data storage technologies. Pre-restore steps include analysis of deduplication indexes to identify data segments that are stored consecutively on storage media. Reading data in aggregate runs of consecutively stored data segments reduces interactions with storage media that hosts the deduplicated data and speeds up retrieval. Parallel reads from multiple storage devices in multi-node replicated file systems also speed up retrieval. An illustrative enhanced media agent pre-fetches data (stored in deduplicated form) in anticipation of read requests that are expected in the restore operation.

Abstract: A method includes, for each feature, performing an anomaly detection process. The anomaly detection process includes selecting, from a plurality of historical data points of the feature, a set of historical data points. Using a machine learning module, a set of scores, each corresponding to one historical data point, is selected. An anomaly threshold is determined based on the set of scores, and compared with a score corresponding to a current data point of the feature to determine whether the current data point is anomalous or not. When the current data point is anomalous, the anomaly detection process includes identifying the feature as an anomalous feature, and including the anomalous feature and the current data point in an anomaly detection report.

Abstract: A method of distributing throughput intelligently amongst a plurality of applications residing at a User Equipment (UE) is provided. The method includes receiving, at the UE, recommended bit rate (RBR) information from a network node, the RBR information indicating a throughput value allocated to the UE, allocating a codec rate from the allocated throughput value to at least one voice over internet protocol (VoIP) application from the plurality of applications, and allocating, from remaining throughput value of the allocated throughput value, a bit rate to each of a plurality of non-VoIP applications from the plurality of applications, based on corresponding throughput requirement associated with the plurality of non-VoIP applications.

Abstract: Hybrid particles having improved electrical conductivity and thermal and chemical stabilities are disclosed. The hybrid particles are for use in conductive pastes. The hybrid particles include a nanoparticle selected from a graphene-containing material, a dichalcogenide material, a conducting polymer, or a combination thereof encapsulated in a conducting metal. The hybrid particles include a nanoparticle selected from a graphene-containing material, a dichalcogenide material, or a combination thereof encapsulated in a conducting polymer, and optionally further in a conducting metal. Suitable conducting metals include nickel or silver. Suitable conducting polymers include polyaniline, polypyrrole, or polythiophene. Suitable dichalcogenide materials include MoS2 or MoSe2. The hybrid particles can further include a conducting polymer layer on an outer surface of the conducting metal. Methods of making the hybrid particles are also disclosed.

Abstract: The present invention relates to a booster composition for enhancing the biogas yield and stabilizing the operation of a biomethanation plant, a method for the preparation of said booster composition and a method for enhancing the biogas yield and stabilizing the operation of a biomethanation plant using said composition by ameliorating the effect of shock conditions like pH and temperature. The booster composition comprises of specifically defined constituents selected from controlled release agents, redox potential balancers, direct interspecies electron transfer (DIET) improvers, micronutrient balancers, and Co-factors.

Abstract: One or more techniques and/or computing devices are provided for resilient replication of storage operations. For example, a first storage controller may host first storage having a replication relationship with second storage hosted by a second storage controller. To improve resiliency against transient network issues of a network between the storage controllers, the first storage controller may implement a queue and retry mechanism to retry replication operations not acknowledge back by the second storage controller within a threshold time. The second storage controller may maintain a cumulative sequence number of a latest replication operation performed in order, an operation response map of replication operations performed out of order, and an operation finder map identifying currently implemented replication operations, which may be used to process incoming replication operations. Single write semantics, write order consistency, and reduction of write amplification may be provided.

Abstract: A method, apparatus, and system for network monitoring are provided. The method retrieves and processes performance data files from each technology type in the network. These performance data files are then loaded into a time series database. At least one key performance indicator is derived from the data. The performance data is organized by region and pool level and then displayed by region and pool level. The method provides configurable thresholds for key performance indicators and alerts users to those thresholds. The apparatus provides a display allowing both monitoring and test functions to be selected. The display is automatically updated based on a predetermined, selectable time interval.

Abstract: Disclosed are techniques for dynamically creating policy-based intermediate certificates to sign device certificates of devices deployed in an enterprise network using ZTD. In one aspect, a method includes receiving network policy information to be used for creating policy-based intermediate certificates, each one of the policy-based intermediate certificates being used by a network controller for signing devices certificates of a different cluster of connected IoT devices; receiving, from an IoT device, a request for registration with the network controller; based on identifying information of the IoT device included in the request, determining one of the policy-based intermediate certificates to sign a device certificate of the loT device; and transmitting, to the IoT device, the device certificate signed using the one of the policy-based intermediate certificates.

Abstract: A receiver circuit may include a first stage and a second stage. The first stage may include a first inverter circuit to generate a first signal based on an input signal and a second inverter circuit to generate a second signal based on the input signal. The second stage may determine a logic state of the input signal by combining the first signal generated by the first inverter circuit and the second signal generated by the second inverter circuit.

Abstract: In an approach for improving the virtual meeting user experience, a processor detects a user disengaging from a virtual meeting having at least two participants for a pre-set period of time or for a pre-set percentage of a total allotted time of a pre-scheduled virtual meeting. A processor retrieves data from a database. A processor prepares a summary that is tailored to a profile of the user and that covers a portion of the virtual meeting during which the user was disengaged. A processor detects the user reconnecting to the virtual meeting. A processor determines whether the user will review the summary before rejoining the virtual meeting. Responsive to determining the user will review the summary before rejoining the virtual meeting, a processor prompts the user with a set of default user preferences to review the summary. A processor outputs the summary to the user.

Abstract: The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I): or a prodrug, solvate, enantiomer, stereoisomer, tautomer, or pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, W, X, Y, s, and Ring A are as described herein.

Abstract: Presented herein are systems and methods for backing up and restoring related backup data stored in different cloud storage tiers in a cloud storage environment. Backup data generated during a backup job is stored to different cloud storage tiers based on the type of data and a storage policy comprising designations of a first cloud storage tier and a second cloud storage tier. Backup metadata and index data is stored in the designated first cloud storage tier and backup payload data is stored in the designated second cloud storage tier. Designations of the storage tiers are based on the attributes associated with each tier of cloud storage. During restore, the backup payload data is recalled from the second storage tier into the first storage tier where it is used to restore to the destination client or customer.