Abstract: The present invention relates to a recombinant microorganism comprising one or more nucleotide sequence(s) encoding: a polypeptide having ent-copalyl pyrophosphate synthase activity; a polypeptide having ent-Kaurene synthase activity; a polypeptide having ent-Kaurene oxidase activity; and a polypeptide having kaurenoic acid 13-hydroxylase activity, whereby expression of the nucleotide sequence(s) confer(s) on the microorganism the ability to produce at least steviol. The recombinant microorganism may also be capable of expressing one or more UDP-glucosyltransferases such that the microorganism is capable of producing one or more steviol glycosides.

Abstract: The present invention provides a process and System for Separation of biomass components into individual components such as cellulose, hemicellulose and lignin. The present invention provides a process for separating lignin in its native form. The cellulose obtained by the process of the present invention is highly reactive for saccharification.

Abstract: Data storage operations, including content-indexing, containerized deduplication, and policy-driven storage, are performed within a cloud environment. The systems support a variety of clients and cloud storage sites that may connect to the system in a cloud environment that requires data transfer over wide area networks, such as the Internet, which may have appreciable latency and/or packet loss, using various network protocols, including HTTP and FTP. Methods are disclosed for content indexing data stored within a cloud environment to facilitate later searching, including collaborative searching. Methods are also disclosed for performing containerized deduplication to reduce the strain on a system namespace, effectuate cost savings, etc. Methods are disclosed for identifying suitable storage locations, including suitable cloud storage sites, for data files subject to a storage policy.

Abstract: The present invention provides means for the production of desired end-products of in vitro and/or in vivo bioconversion of biomass-based feed stock substrates, including but not limited to such materials as starch and cellulose. In particularly preferred embodiments, the methods of the present invention do not require gelatinization and/or liquefaction of the substrate.

Abstract: The invention relates to a biocompatible, non-biodegradable, and non-toxic polymer of formula (I), comprising of three monomeric units, selected from 1-Vinylpyrrolidne (VP), N-Isopropylactylamide (NIPAM), and ester of Maleic anhydride and Polyethylene glycol (MPEG), cross-linked with a bi-functional vinyl derivative, of high purity and substantially free of respective toxic monomeric contaminants, and a process for preparation thereof. The invention further relates to nanoparticulate pharmaceutical compositions of poorly water-soluble drugs or compounds comprising the polymer of the invention, which are safe, less-toxic and convenient for bedside administration to patients in need thereof. Furthermore, the invention relates to a highly selective method for preparation of nanoparticulate pharmaceutical compositions of poorly water-soluble drugs or compounds.

Abstract: The present invention relates to a method and corresponding system for modeling a musculo-skeletal system. An embodiment of the method of the invention begins by scaling and positioning a musculo-skeletal model to correspond with motion capture data of a subject. Next, kinematically consistent motion data is generated from the motion capture data and then an inverse dynamic analysis of the musculo-skeletal model is performed using the generated kinematically consistent motion data, such that at least one analysis result is generated. The musculo-skeletal model is then updated to correspond with the at least one analysis result of the inverse dynamic analysis. Finally, the muscle activation of the updated musculo-skeletal model is optimized by determining at least one muscle force using the updated musculo-skeletal model, and by further updating the updated musculo-skeletal model to correspond with the determined at least one muscle force.

Abstract: A ventilation system for a machine including an engine, an engine compartment having an interior, a secondary compartment having an interior, and a sensor. The ventilation system has a ventilation fan having a fan outlet, and a duct configured to direct air from the fan outlet to at least two of the interior of the engine compartment, the interior of the secondary compartment, and the sensor.

Abstract: An external fixation system and method for realigning, compressing or distracting broken bones has a planar ring element with an adjustable device having a body releasably mounted on the ring element. The adjustable device includes a first member for movement in a direction generally perpendicular to the ring element. A second member is mounted on the first member for movement in a direction parallel to the first member and with respect to a circumference of the planar ring element. The method includes inserting a k-wire through a first piece of bone and affixing the k-wire to the ring element. Then inserting a second k-wire through a second piece of bone and affixing the k-wire to the adjustable device second member. The pieces of bone are realigned, compressed or distracted by adjusting at least one of a first and second adjustable members forming the device.

Abstract: A method, system, computer program product, and computer program storage device for transforming a high-level policy associated with a high layer to a low-level policy associated with a low layer. Mapping between high-level objects in a high layer and low-level objects in a low layer is derived by an automated discovery tool. The high-level policy is mapped to the low-level policy according to the mapping (e.g., by substituting the high-level objects with the low-level objects and by performing a syntax transformation). In one embodiment, a low-level policy is transformed to a high-level policy according to the mapping. As exemplary embodiments, policy transformations in traffic shaping and data retention are disclosed.

Abstract: An input/output circuit layout has a first section in which first transistors having a thicker gate oxide are located and a second section in which second transistors having a thinner gate oxide are located. Due to process technology constraints, the gates of all of the second transistors are oriented in a single common direction. The second section has a perimeter having a square shape including a first edge and a second edge adjacent to the first edge. First connection pins coupled to the second transistors are provided with an orientation that extends inwardly from and perpendicular to the first edge. Second connection pins coupled to the second transistors are provided with an orientation that extends inwardly from and perpendicular to said second edge. The square shape and presence of pins on adjacent first and second edges permits rotation of the second section to fit within different orientations of the layout.

Abstract: A method and system for streaming media to a client from a media server is described. In some examples, the system utilizes a virtualization layer to generate a virtual computing environment, or virtual machine, at a UPnP server, which is configured to receive requests for media, identify locations for the media within the secondary storage devices, access the media, and present the media to a client computing device associated with the media requests.

Abstract: An external fixation system has a planar ring with an adjustable device having a body releasably mounted on the ring. The adjustable device includes a first member for movement in a direction generally perpendicular to the ring. A second member is mounted on the first member for movement in a direction parallel to a side wall of the planar ring. A method for treating a broken bone includes providing an external fixation system and inserting a first k-wire or half pin through a first piece of the bone and affixing the first k-wire or half pin to the ring, then inserting a second k-wire or half pin through a second piece of bone and affixing the second k-wire or half pin to the adjustable device. The pieces of bone are realigned, compressed, or distracted by adjusting at least one of the first and second adjustable members.

Abstract: An action framework system provides context-based actions in association with a source application. The source application detects selection of a content element presented by the source application. The content element is associated with an application identifier identifying a target application and an action identifier identifying an operation to be executed by the target application on the content element. The target application identified by the application identifier is executed to perform the operation identified by the action identifier on the content element, responsive to detection of the selection of the content element. In one implementation, the source application is a search feature providing different contexts of search results (e.g., from a local file system search, a local application content search, a Web search, a remote application content search).

Abstract: A surgical fastener applying apparatus (10) including a cartridge supporting section (200), an anvil supporting section (100) having a longitudinal axis and including a distal anvil portion (104) and a proximal handle portion (102), including a first longitudinally extending slot (109) extending therealong. A clamping lever (300) having a proximal portion and a distal portion is movable from an undamped position to a clamped position to releasably secure the anvil supporting section in close approximation with the cartridge supporting section. A firing assembly (500) includes a firing knob (552), the firing knob movable within the longitudinally extending slot from a first proximal position to a second distal position to fire fasteners (402) supported in the cartridge supporting section.

Abstract: The present invention provides a cost effective biotechnological process for production of bio-fuels from isolated and characterized microalgae. The algal strains used in the present invention having higher biomass, higher lipid productivity, higher pH and temperature tolerance are selected from the group consisting of Chlorella vulgaris iOC-1, Chlorella vulgaris iOC-2, Chlorella kessleri, Botrococcus bruni, Dunaliella salina and Nannochloris oculat or a combination thereof having 95-100% similarity with 18s ribosomal nucleic acids nucleotide sequences (rDNA) given for Seq. ID I, Seq. ID 2, Seq. ID 3, Seq. ID 4, Seq. ID 5 and Seq. ID 6. The present process of bio-fuel production comprises the steps of producing lipid from green algae in bioreactors by various novel steps and extracting oil from dried algal cells and ultimately producing biodiesel by transesterification of the said extracted oil.

Abstract: An external fixator system comprising at least two fixation plates which are arranged at a distance to each another, at least one adjustable length strut having a first end region and a second end region which are in connection with the fixation plates and at least one actuation unit to adjust the length of the strut in order to adjust the distance and/or orientation between the fixation plates. The actuation unit is in a fixed connection with at least one of the fixation plates as well as with at least one of the end regions of the respective strut in order to connect the strut with the fixation plate. The actuation unit comprises a feedback unit which provides the user with a feedback concerning the degree of the actuation.

Abstract: One or more techniques and/or systems are provided for dynamically maintaining user centric data. For example, a data provider app may have knowledge about user centric data associated with a user (e.g., a social network app may have contact information for a social network friend of the user). A user centric profile may be defined for the user centric data based upon information provided by the data provider app (e.g., a contact card may be generated for the social network friend). Responsive to receiving a request for the user centric profile from a requestor app (e.g., an event planning app), the user centric profile may be exposed to the user but not to the requestor app for security and/or privacy purposes. For example, an operating system may present at least some of the user centric profile within an operating system user interface.

Abstract: The present invention relates to a simple and convenient process for preparing solid lipid sustained release nanoparticles for delivery of drugs/vitamins, preferably fat soluble vitamins and more specifically Vitamin D3 and retinoic acid (RA). The process involves microemulsion technique. The nanoparticles of Vitamin D3 and RA obtained by the process of the present invention have utility in treatment of diseases like tuberculosis. Use may be extended to other diseases like AMD, diabetic retinopathy, cancers, hyperpigmentation, acne, and osteoporosis.

Abstract: Controlled release oral dosage formulations containing calcium channel blocker and processes for preparation thereof, are provided for once a day treatment. The active agent is preferably a dihydropyridine calcium channel blocker, such as nisoldipine. In one embodiment, the formulation provides controlled release of micronized nisoldipine with one or more pH independent release controlling polymers. The controlled release matrix formulation is advantageous and can be prepared by a simple, economically viable process as compared to complex core-coat prior-art versions.

Abstract: A system and method for soft-field reconstruction are provided. One method includes obtaining applied input and measured output information for an excited object using a plurality of transducers and forming an admittance matrix based on the applied input and measured output information. The method also includes determining a plurality of moments using the admittance matrix and calculating a property distribution of the excited object using the plurality of moments.