Abstract: A distributed voice applications system includes a voice applications rendering agent and at least one voice applications agent that is configured to provide voice applications to an individual user. A management system may control and direct the voice applications rendering agent to create voice applications that are personalized for individual users based on user characteristics, information about the environment in which the voice applications will be performed, prior user interactions and other information. The voice applications agent and components of customized voice applications may be resident on a local user device which includes a voice browser and speech recognition capabilities. The local device, voice applications rendering agent and management system may be interconnected via a communications network.

Abstract: Provided herein are RET kinase inhibitors according to the formula: pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods for their use in the treatment of diseases that can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders. A, R1, n, X1, X2, X3, X4, and R2 have the meanings given in the specification.

Abstract: The present invention provides antibodies that specifically bind to CD123. The invention further relates to immunoconjugates (e.g., antibody-drug conjugates, or ADCs) comprising such antibodies, antibody encoding nucleic acids, and methods of obtaining such antibodies. The invention further relates to therapeutic methods for use of these antibodies and ADCs for the treatment of a condition associated with cells expressing CD123 (e.g., cancer or autoimmune disease).

Abstract: Machine learning version management method for a prediction service includes receiving a prediction request, determining application metadata for the request that defines routing logic and a machine learning framework version, determining model metadata for the request that defines at least one model and at least one model version, forwarding the prediction request to the at least one model with the at least one model version, and returning a prediction from the at least one model to a requestor.

Abstract: One embodiment provides an apparatus. The apparatus includes a lightweight cryptographic engine (LCE), the LCE is optimized and has an associated throughput greater than or equal to a target throughput.

Abstract: Stacked circuit board structures and methods of assembly are described. In an embodiment, a stacked circuit board structure includes first circuit board and a second circuit board including a plurality of pins mounted thereon, and the plurality of pins are secured in a plurality of receptacles that are coupled with the first circuit board to provide electrical connection between the first circuit board and the second circuit board.

Abstract: A method includes first determining among a plurality of cells a first set of cells that are anomalous, second determining among remaining cells a second set of cells that are anomalous, and identifying a resulting set of anomalous cells being a combination of the first set and the second set of anomalous cells. The first determining is based on input data of a plurality of first features of each cell among the plurality of cells, and a first machine learning operation. The second determining is based on the input data of the plurality of first features of each cell among the remaining cells, and a second machine learning operation different from the first machine learning operation.

Abstract: An integrated circuit includes an input pad and a Schmitt trigger coupled to the input pad. The Schmitt trigger includes a first inverter and a second inverter. The Schmitt trigger includes a pull-up transistor coupled to an input of the second inverter and configure to supply a high reference voltage to the input of the second inverter.

Abstract: The present invention relates to a process for valorization of low-cost alkane rich feedstock. More specifically, the present invention relates to the selective conversion of alkane rich kerosene to value-added products like mono/dicarboxylic acid, fatty acids and biosurfactants using mutant yeast strain and a heterogenous nano-catalyst. The present invention also provides a mutant yeast strain for selective conversion of alkane rich refinery stream from a substrate containing hydrocarbons. The mutant yeast strain of the present invention is able to consume the sulfur content in the feed and results in the desulfurization of the alkane rich feedstock.

Abstract: A method, computer system, and a computer program product for persona-based navigation is provided. The present invention may include creating a persona. The present invention may include developing a routing system. The present invention may include enabling a user with at least one route option based on the created persona. The present invention may include displaying a selected route.

Abstract: The present invention provides compositions comprising PAMAM dendrimers conjugated with one or more biologically active agents, and their use systemically to target activated microglia/macrophages in retina/choroid and generally, inflammatory and/or angiogenic diseases of the eye.

Abstract: In one embodiment, a system includes first host machines implementing a public-cloud computing environment, wherein at least one of the first host machines includes a resource manager that provides a public-cloud resource interface through which one or more public-cloud clients interact with one or more virtual machines, and second host machines implementing a private-cloud computing environment, wherein at least one of the second host machines includes one or more private-cloud virtual machines, wherein at least one of the first host machines further includes a private-cloud VM resource provider through which the resource manager interacts with the private-cloud virtual machines, wherein the VM resource provider translates requests to perform virtual machine operations from a public-cloud-resource interface to a private-cloud virtual machine interface, and the private-cloud virtual machines perform the requested virtual machine operations in response to receiving the translated requests from the VM resource

Abstract: Polynomial multiplication for side-channel protection in cryptography is described. An example of a apparatus includes one or more processors to process data; a memory to store data; and polynomial multiplier circuitry to multiply a first polynomial by a second polynomial, the first polynomial and the second polynomial each including a plurality of coefficients, the polynomial multiplier circuitry including a set of multiplier circuitry, wherein the polynomial multiplier circuitry is to select a first coefficient of the first polynomial for processing, and multiply the first coefficient of the first polynomial by all of the plurality of coefficients of the second polynomial in parallel using the set of multiplier circuits.

Abstract: A process for selective capture of CO2 from gaseous mixture comprising of: (a) spraying a bio-amine cluster; (b) capturing CO2 through bio-amine cluster; and (c) desorption of CO2 through solar assisted electro de-amination, wherein the bio-amine cluster is comprises of: an amine cluster comprising of a quaternary Isobutylamine (IB) with amine terminated Poly(L-lactide) as the chelating agent; a cluster stabilizing agent; a cluster micelle stabilizing agent; and a carbonic anhydrase (CA) functionalized matrix in 0.05-0.2 wt % of total wt % of bio-amine cluster and wherein the CA is obtained from a source selected from the group consisting of Bacillus thermoleovorans, Pseudomonas fragi, Bacillus stearothermophilus and Arthrobacter sp. and a process for production of bio-amine cluster.

Abstract: An improved content indexing system is disclosed herein that content indexing system combines the functionality of the backup metadata database and the content index database into a single backup and content index database to avoid the need to perform synchronization operations. By using a single backup and content index database, the content indexing system also reduces the computing performance costs that would be associated with the synchronization operations as the amount of indexed content increases, thereby solving scalability issues.

Abstract: Approaches, techniques, and mechanisms are disclosed for generating, enhancing, applying and updating knowledge neurons for providing decision making information to a wide variety of client applications. Domain keywords for knowledge domains are generated from domain data of selected domain data sources, along with keyword values for the domain keywords, and are used to generate knowledge artifacts for inclusion in knowledge neurons. These knowledge neurons may be enhanced by domain knowledge data sets found in various data sources and used to generate neural responses to neural queries received from the client applications. Neural feedbacks may be used to update and/or generate knowledge neurons.

Abstract: The technology disclosed relates to runtime execution of configuration files on reconfigurable processors with varying configuration granularity. In particular, the technology disclosed relates to a runtime logic that is configured to receive a set of configuration files for an application, and load and execute a first subset of configuration files in the set of configuration files and associated application data on a first reconfigurable processor. The first reconfigurable processor has a first level of configurable granularity. The runtime logic is further configured to load and execute a second subset of configuration files in the set of configuration files and associated application data on a second reconfigurable processor. The second reconfigurable processor has a second level of configurable granularity that is different from the first level of configurable granularity.

Abstract: A method and system of a re-assembly middleware in FPGA for processing TCP segments into application layer messages is disclosed. In recent years, the communication speed in digital systems has increased drastically and thus has brought in a growing need to ensure a good/high performance from the FPGA services. The disclosure proposes a re-assembly middleware in the FPGA for processing TCP segments into application layer messages at a pre-defined frequency for a good/high performance. The pre-defined frequency is a high frequency performance feature of the re-assembly middleware, wherein the FPGA's implementation frequency is at atleast 300 MHz based on a memory optimization technique. The memory optimization technique includes several strategies such registering an output and slicing memories.

Abstract: Methods and systems for rendering lists of instructions and performing actions associated with those lists are described herein. In some embodiments, an individual may request that a voice activated electronic device associated with their user account assist in performing a task using a list of instructions. The list of instructions may include metadata that indicates actions capable of being performed by additional Internet of Things (“IoT”) devices. When the instructions are rendered, an instructions speechlet may recognize the metadata and may cause one or more of the IoT devices to perform a particular action. Furthermore, the metadata may also correspond to content capable of being rendered by the voice activated electronic device to assist the individual in performing a particular step of the instructions.

Abstract: This invention relates to syndet-based compositions having pH of 4.5 to 5.5 wherein use of caprylic acid has been unexpectedly found to enhance bacterial kill.