Patents by Inventor Mario Rottlander

Mario Rottlander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted morpholine and thiomorpholine derivatives
    Publication number: 20100063036
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: November 3, 2009
    Publication date: March 11, 2010
    Applicant: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Nikolay Khanzhin, Andreas Ritzén, William Patrick Watson
  • Substituted morpholine and thiomorpholine derivatives
    Patent number: 7632835
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives or the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Grant
    Filed: January 28, 2009
    Date of Patent: December 15, 2009
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornoe, Mario Rottlander, Nikolay Khanzhin, Andreas Ritzen, William Patrick Watson
  • Substituted aniline derivatives
    Patent number: 7601870
    Abstract: The present invention relates to aniline derivatives of the general formula I or salts thereof, described therein, and their use.
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: October 13, 2009
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Daniel Rodriguez Greve, Nikolay Khanzhin, Andreas Ritzén, William Patrick Watson
  • METHODS OF USING SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES
    Publication number: 20090143369
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: January 28, 2009
    Publication date: June 4, 2009
    Applicant: H. LUNDBECK A/S
    Inventors: Christian Wenzel Tornoe, Mario Rottlander, Nikolay Khanzhin, Andreas Ritzen, William Patrick Watson
  • SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES
    Publication number: 20090137571
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives or the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: January 28, 2009
    Publication date: May 28, 2009
    Applicant: H. LUNDBECK A/S
    Inventors: Christian Wenzel Tornoe, Mario Rottlander, Nikolay Khanzhin, Andreas Ritzen, William Patrick Watson
  • USE OF KCNQ-OPENERS FOR TREATING OR REDUCING THE SYMPTOMS OF SCHIZOPHRENIA
    Publication number: 20090118285
    Abstract: The invention relates to a novel method for treating or reducing the symptoms of schizophrenia, said method comprising administering to a host in need thereof an effective amount of a compound able to selectively increase the ion flow through KCNQ potassium channels. Furthermore the invention relates to the use of selective KCNQ potassium channel openers for the preparation of a pharmaceutical composition for treating or reducing the symptoms of schizophrenia and related symptoms, disorders and diseases. Furthermore the invention relates to a method of screening for a compound, which is a selective KCNQ potassium channel opener and which is capable of having an anti-psychotic potential.
    Type: Application
    Filed: February 2, 2007
    Publication date: May 7, 2009
    Applicant: H. Lundbeck A/S
    Inventors: Henriette Husum Bak-Jensen, Christian Wenzel Tornoe, Mario Rottlander, Daniel Rodriguez Greve, Nikolay Khanzhin, Andreas Ritzen, William Patrick Watson
  • Substituted morpholine and thiomorpholine derivatives
    Patent number: 7501414
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: March 10, 2009
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Nikolay Khanzhin, Andreas Ritzèn, William Patrick Watson
  • Substituted Pyridine Derivatives
    Publication number: 20080318953
    Abstract: The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders.
    Type: Application
    Filed: March 2, 2006
    Publication date: December 25, 2008
    Applicant: H. LUNDBECK A/S
    Inventors: Christian Wenzel Tornoe, Nikolay Khanzhin, Mario Rottlander, William Patrick Watson, Daniel Rodriguez Greve
  • Heteroaryl derivates, their preparation and use
    Patent number: 7393845
    Abstract: A heteroaryl derivative having the formula (I).
    Type: Grant
    Filed: June 5, 2007
    Date of Patent: July 1, 2008
    Assignee: H. Lundbeck A/S
    Inventors: Mario Rottländer, Ejner Knud Moltzen, Ivan Mikkelsen, Thomas Ruhland, Kim Andersen, Christian Krog-Jensen
  • 1,2,4-Triaminobenzene derivatives useful for treating disorders of the central nervous system
    Patent number: 7368472
    Abstract: The present invention concerns 1,2,4-triaminobenzene derivatives of the general formula I or pharmaceutically acceptable salts thereof and the use thereof.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: May 6, 2008
    Assignee: H. Lundbeck A/S
    Inventors: Mario Rottlander, Andreas Ritzen, Morten Bang Norgaard, Nikolay Khanzhin, Christian Wenzel Tornoe
  • Indole derivatives
    Patent number: 7342015
    Abstract: A heteroaryl derivative having the formula (I).
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: March 11, 2008
    Assignee: H. Lundbeck A/S
    Inventors: Mario Rottländer, Ejner Knud Moltzen, Ivan Mikkelsen, Thomas Ruhland, Kim Andersen, Christian Krog-Jensen
  • Novel heteroaryl derivatives, their preparation and use
    Publication number: 20080027071
    Abstract: A heteroaryl derivative having the formula (I). The compounds of the invention are considered useful for the treatment of affective disorders such as general anxiety disorder, panic disorder, obsessive compulsive disorder, depression, social phobia and eating disorders, and neurological disorders such as psychosis.
    Type: Application
    Filed: June 5, 2007
    Publication date: January 31, 2008
    Applicant: H. Lundbeck A/S
    Inventors: Mario Rottlander, Ejner Moltzen, Ivan Mikkelsen, Thomas Ruhland, Kim Andersen, Christian Krog-Jensen
  • Substituted pyrimidine derivatives
    Publication number: 20070066612
    Abstract: The present invention relates to pyrimidine derivatives of the general formula I or salts thereof and their use.
    Type: Application
    Filed: September 6, 2006
    Publication date: March 22, 2007
    Inventors: Nikolay Khanzhin, Daniel Greve, Mario Rottlander
  • Substituted indoline and indole derivatives
    Publication number: 20060264496
    Abstract: The present invention relates to aniline derivatives of the general formula I or pharmaceutically acceptable salts thereof, [Formula (I)], and their use.
    Type: Application
    Filed: April 23, 2004
    Publication date: November 23, 2006
    Applicant: H. Lundbeck A/S
    Inventors: Nikolay Khanzhin, Mario Rottlander, William Watson
  • Novel indole derivatives
    Publication number: 20060258678
    Abstract: A heteroaryl derivative having the formula (I). The compounds of the invention are considered useful for the treatment of affective disorders such as general anxiety disorder, panic disorder, obsessive compulsive disorder, depression, social phobia and eating disorders, and neurological disorders such as psychosis.
    Type: Application
    Filed: June 27, 2002
    Publication date: November 16, 2006
    Inventors: Mario Rottländer, Ejner Moltzen, Ivan Mikkelsen, Thomas Tuhland, Kim Andersen, Christian Krog-Jensen
  • Substituted p-diaminobenzene derivatives
    Publication number: 20060183791
    Abstract: The present invention relates to aniline derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: March 18, 2004
    Publication date: August 17, 2006
    Applicant: H. LUNDBECK A/S
    Inventors: Nikolay Khanzhin, Mario Rottlander, Andreas Ritzen, William Watson
  • Substituted aniline derivatives
    Publication number: 20060167087
    Abstract: The present invention relates to aniline derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: March 12, 2004
    Publication date: July 27, 2006
    Applicant: H. Lundbeck A/S
    Inventors: Daniel Greve, Mario Rottlander, William Watson
  • Substituted morpholine and thiomorpholine derivatives
    Publication number: 20060167248
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: December 21, 2005
    Publication date: July 27, 2006
    Inventors: Christian Tornoe, Mario Rottlander, Nikolay Khanzhin, Andreas Ritzen, William Watson
  • Substituted aniline derivatives
    Publication number: 20060155121
    Abstract: The present invention relates to aniline derivatives of the general formula I or salts thereof and their use.
    Type: Application
    Filed: December 20, 2005
    Publication date: July 13, 2006
    Inventors: Christian Tornoe, Mario Rottlander, Daniel Greve, Nikolay Khanzhin, Andreas Ritzen, William Watson
  • 1,2,4-Triaminobenzene derivatives useful for treating disorders of the central nervous system
    Publication number: 20060014822
    Abstract: The present invention concerns 1,2,4-triaminobenzene derivatives of the general formula I or pharmaceutically acceptable salts thereof and the use thereof.
    Type: Application
    Filed: December 18, 2003
    Publication date: January 19, 2006
    Inventors: Mario Rottlander, Andreas Ritzen, Morten Norgaard, Nikolay Khanzhin, Christian Tornoe