Patents by Inventor Mario Rottlander

Mario Rottlander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing Grignard compounds
    Patent number: 6899830
    Abstract: The invention relates to a process for preparing Grignard compounds of the formula I. The invention additionally relates to compounds of the formula I and to polymer-bound compounds of the formula Ia. The invention further relates to the use of the process for preparing substance libraries and to the use of the compounds of the formulae I and Ia in chemical synthesis.
    Type: Grant
    Filed: April 1, 1999
    Date of Patent: May 31, 2005
    Assignee: BASF
    Inventors: Laure Boymond, Mario Rottländer, Gerard Cahiez, Paul Knochel
  • Novel heteroaryl derivatives, their preparation and use
    Publication number: 20040248883
    Abstract: A heteroaryl derivative having the formula (I). The compounds of the invention are considered useful for the treatment of affective disorders such as general anxiety disorder, panic disorder, obsessive compulsive disorder, depression, social phobia and eating disorders, and neurological disorders such as psychosis.
    Type: Application
    Filed: July 6, 2004
    Publication date: December 9, 2004
    Inventors: Mario Rottlander, Ejner K. Moltzen, Ivan Mikkelsen, Thomas Ruhland, Kim Andersen, Christian Krog-Jensen
  • Substituted phenyl-piperazine derivatives, their preparation and use
    Patent number: 6699864
    Abstract: The present invention provides compounds of the formula: wherein R1-R8, X, Y, Z, n and m are defined in the application. The compounds of the invention have affinity for the 5-HT1A receptor.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: March 2, 2004
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Christian Krog-Jensen, Mario Rottländer, Gitte Mikkelsen, Ejner Knud Moltzen, Kim Andersen
  • Substituted phenyl-piperazine derivatives, their preparation and use
    Publication number: 20030125320
    Abstract: The present invention provides compounds of the formula: 1
    Type: Application
    Filed: June 20, 2002
    Publication date: July 3, 2003
    Applicant: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Christian Krog-Jensen, Mario Rottlander, Gitte Mikkelsen, Ejner Knud Moltzen, Kim Andersen
  • Phenylpiperazinyl derivatives
    Publication number: 20030083336
    Abstract: The present invention relates to a novel class of substituted phenylpiperazinyl derivatives having the formula 1
    Type: Application
    Filed: June 25, 2002
    Publication date: May 1, 2003
    Applicant: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Jan Kehler, Kim Andersen, Benny Bang-Andersen, Mario Rottlander
  • Novel heteroaryl derivatives, their preparation and use
    Publication number: 20030050306
    Abstract: A heteroaryl derivative having the formula (I) 1
    Type: Application
    Filed: June 25, 2002
    Publication date: March 13, 2003
    Applicant: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Christian Krog-Jensen, Ivan Mikkelsen, Mario Rottlander, Gitte Mikkelsen, Ejner Knud Moltzen, Kim Andersen
  • Novel indole derivatives
    Publication number: 20030050307
    Abstract: The invention provide compounds of the formula 1
    Type: Application
    Filed: June 25, 2002
    Publication date: March 13, 2003
    Applicant: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Christian Krog-Jensen, Mario Rottlander, Gitte Mikkelsen, Kim Andersen, Ejner Knud Moltzen
  • Method for the preparation of substituted benzene derivatives
    Publication number: 20030040639
    Abstract: A method for the preparation of selectively substituted benzene derivatives by application of solid phase synthesis is disclosed. In particular, the invention provides a novel method for the preparation of substituted benzene derivatives containing two or three groups bound to the benzene ring via nitrogen-, oxygen-, sulphur-, selenium- or carbon-carbon bonds, by application of solid phase chemistry alone or in combination with post cleavage solution phase derivatisation.
    Type: Application
    Filed: June 26, 2002
    Publication date: February 27, 2003
    Applicant: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Mario Rottlander, Kim Andersen
  • Benzofuran derivatives, their preparation and use
    Patent number: 6492374
    Abstract: The present invention relates to benzofuran derivatives having general Formula (I) wherein A is selected from (1), (2), (3), (4) wherein Z is O or S; s is 0 or 1; q is 0 or 1; R4 is hydrogen, C1-6-alkyl, C2-6-alkenyl, C26-alkynyl, C1-6-alkyl-aryl, or C1-6-alkyl-O-aryl; D is a spacer group selected from branched or straight chain C1-6-alkylene, C2-6-alkenylene and C2-6-alkynylene; its enantiomers, and pharmaceutically acceptable acid addition salt thereof. The compounds are potently binding to the 5-HT1A receptor.
    Type: Grant
    Filed: June 4, 2001
    Date of Patent: December 10, 2002
    Assignee: H. Lundbeck A/S
    Inventors: Kim Andersen, Mario Rottländer, Klaus Peter Bøgesø, Henrik Pedersen, Thomas Ruhland, Robert Dancer
  • Method for the stereoselective production of grignard compounds and use thereof
    Patent number: 6432326
    Abstract: A process for the stereoselective preparation of Grignard compounds of the formula I and polymer-bonded compounds of the formula Ia is described. The process can be used for producing substance reference libraries and the compounds of the formulae I and Ia can be used in stereoselective chemical synthesis.
    Type: Grant
    Filed: January 2, 2001
    Date of Patent: August 13, 2002
    Assignee: BASF Aktiengesellschaft
    Inventors: Laure Boymond, Mario Rottländer, Gerard Cahiez, Paul Knochel
  • Benzofuran derivatives, their preparation and use
    Publication number: 20020032205
    Abstract: The present invention relates to benzofuran derivatives having general Formula (I) 1
    Type: Application
    Filed: June 4, 2001
    Publication date: March 14, 2002
    Applicant: H. Lundbeck A/S
    Inventors: Kim Andersen, Mario Rottlander, Klaus Peter Bogeso, Henrik Pedersen, Thomas Ruhland, Robert Dancer