Abstract: A laser device is disclosed that provides at least an ultraviolet laser beam and preferably both an ultraviolet laser beam and a visible laser beam. The laser device includes a semiconductor laser device (e.g. a laser diode) to generate visible laser light which is coupled into a frequency doubling crystal taking the form of a single crystal thin film frequency-doubling waveguide structure. The single crystal thin film frequency-doubling waveguide converts a portion of the visible light emitted by the laser diode into ultraviolet light. Both visible and ultraviolet laser light is emitted from the waveguide. As an example, the single crystal thin film frequency-doubling frequency doubling waveguide includes a frequency doubling crystal region composed of ?-BaB2O4 (?-BBO), a cladding region composed of materials that are transparent or nearly transparent at the wavelength of the ultraviolet laser light beam and a supporting substrate composed of any material.

Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.

Abstract: A system and method for processing a plurality of data storage and retrieval management or manifest files in a virtual data storage system. A plurality of individual management/manifest files, which are each used to track data management information stored on a data storage device, are merged into a single management or manifest file that can then be used to subsequently manage the input or import of data such as logical volumes from one or more physical media. This single management/manifest file could be used, for example, in a media import operation for importing a media cartridge or device into a media library such as a data storage library.

Abstract: Apparatus, systems, and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The system may include one or more markers implantable within or around the target tissue region, and a probe for transmitting and receiving electromagnetic signals to detect the one or more markers. During use, the marker(s) are into a target tissue region, and the probe is placed against the patient's skin to detect and localize the marker(s). A tissue specimen, including the lesion and the marker(s), is then removed from the target tissue region based at least in part on the localization information from the probe.

Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.

Abstract: A method of assessing the viability of a cell comprises incubating the cell in a culture medium. The culture medium includes a plurality of amino acids and the change in concentration in the medium of at least one amino acid is determined.

Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.

Abstract: An air particle sample cassette enables concurrent or sequential collection of air particle samples. The dual air particle sample cassette has top and bottom covers that fit together to provide an airtight seal between them. The airtight seal may be provided by adhesive or otherwise. However, a close fit between the two also aids in obtaining an airtight seal. The top cover has tapering inlets circumscribed by channels. The inlets taper to create increased air speed at the exit slit of the inlets. The inlets have rounded tops for greater collection of air and the circumscribing channels provide means by which plastic caps or otherwise may be used to protect the inlets from collecting air until desired. The sample plate or collecting slide is fitted to the bottom of the top cover and obstructs the direct flow of air to the exit port. The collecting slide is protected from contact with other cassette elements by spacers or sidewalls which generally leave the corners of the bottom cover open.

Abstract: A system for easily transferring an intraocular lens (IOL) from a lens case to an inserter, and then into a patient's eye. The lens case has a transfer mechanism therein which retains the IOL until engagement with the inserter. The transfer mechanism may include jaws having a closed configuration for retaining the IOL and an open configuration for releasing the IOL. Engagement of the inserter with the lens case automatically opens the jaws and transfers the IOL to the inserter. The IOL is transferred into a load chamber of a nosepiece rotatably coupled to a handpiece. After transfer of the IOL, the nosepiece is rotated from a load position to a delivery position. The IOL may have an optic and a haptic coupled to the optic, and the lens case may be capable of configuring the haptic as desired to facilitate its transfer into an inserter and/or into the eye. For instance, the lens case may fold one or both of the haptics over the optic.

Abstract: A lens case for storing an intraocular lens contains a housing for storing an intraocular lens and a support member configured to support the intraocular lens. The support member includes a plurality of jaws, the jaws having a closed configuration for holding the intraocular lens and an open configuration for releasing the intraocular lens. The lens case further comprises a passage formed when the jaws are in the open configuration, the passage including an opening in the lens case for transfer of the intraocular lens into an intraocular lens inserter. The lens case may further comprise an intraocular lens that is disposed between the jaws, the intraocular lens comprising an optic and a haptic coupled to the optic. The lens case may be configured to maintain the haptic in either a first position in which a distal portion of the haptic is disposed farther from the optic or a second position in which the distal portion of the haptic is disposed closer to optic.

Abstract: The present invention describes a means for fixing skin care ingredients on the surface of non-woven webs and cellulosic mats. The active ingredients can be released (deposited) onto the skin by normal triggering mechanisms, which include the action of water or urine or by friction or rubbing. The fixative systems described herein provide the ability to control high load levels while not interfering with the wettabliity of the fabric or paper. Additionally, incompatible/reactive ingredients can be treated onto the same web and are kept as separate particles fixed to the surface until released.

Abstract: A lens and cartridge packaging system and method of use which simplify the removal and transfer of an IOL to an IOL insertion device is disclosed. The packaging system enables a user to easily load an IOL into a cartridge without the use of forceps. In addition, the packaging system also allows a user to fold and insert the IOL into a cartridge without damaging the IOL and/or compromising IOL sterility. In addition, the related methods of use minimize and/or eliminate damage to the IOL during unpackaging, folding, transfer and loading procedures.

Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.

Abstract: A lens and cartridge packaging system and method of use which simplify the removal and transfer of an IOL to an IOL insertion device is disclosed. The packaging system enables a user to easily load an IOL into a cartridge without the use of forceps. In addition, the packaging system also allows a user to fold and insert the IOL into a cartridge without damaging the IOL and/or compromising IOL sterility. In addition, the related methods of use minimize and/or eliminate damage to the IOL during unpackaging, folding, transfer and loading procedures.

Abstract: An air particle sample cassette enables concurrent or sequential collection of air particle samples. The dual air particle sample cassette has top and bottom covers that fit together to provide an airtight seal between them. The airtight seal may be provided by adhesive or otherwise. However, a close fit between the two also aids in obtaining an airtight seal. The top cover has tapering inlets circumscribed by channels. The inlets taper to create increased air speed at the exit slit of the inlets. The inlets have rounded tops for greater collection of air and the circumscribing channels provide means by which plastic caps or otherwise may be used to protect the inlets from collecting air until desired. The sample plate or collecting slide is fitted to the bottom of the top cover and obstructs the direct flow of air to the exit port. The collecting slide is protected from contact with other cassette elements by spacers or sidewalls which generally leave the corners of the bottom cover open.

Abstract: The present invention describes a means for fixing skin care ingredients on the surface of non-woven webs and cellulosic mats. The active ingredients can be released (deposited) onto the skin by normal triggering mechanisms, which include the action of water or urine or by friction or rubbing. The fixative systems described herein provide the ability to control high load levels while not interfering with the wettabliity of the fabric or paper. Additionally, incompatible/reactive ingredients can be treated onto the same web and are kept as separate particles fixed to the surface until released.

Abstract: A cartridge for delivering an intraocular lens into the eye of a subject that comprises a body disposed along a longitudinal axis having a distal end and a proximal end, and a tapered lumen disposed along the longitudinal axis having an aperture at the distal end of the body. The aperture and at least a portion of the tapered lumen each consist of an upper portion and a lower portion. The upper portions of the aperture and lumen each have a first width and a cross-section that is generally arcuate. The lower portions of the aperture and lumen each have a cross-section that is generally horizontally disposed and have a second width that is greater than the first width of the aperture and lumen. The cartridge may be loaded with an intraocular lens using a packaging system. The intraocular lens may be placed into the eye of a subject using a corresponding inserter having a pushrod with a saddle disposed at the tip thereof. The intraocular lens is preferably draped over the saddle during insertion.

Abstract: An insertion system is provided for delivering an intraocular lens into the eye of a subject. The insertion system comprises an inserter for delivering the intraocular lens and a lens case for holding the intraocular lens prior to delivery. The inserter comprises handpiece having a longitudinal axis, a proximal end, and a distal end. The inserter further comprises a nosepiece disposed at the distal end of the inserter, the nosepiece having a rotational axis that is substantially perpendicular to the longitudinal axis and a load chamber with a transfer interface for receiving the intraocular lens. The lens case has a transfer port for transferring the intraocular lens from the lens case into the load chamber. Once the intraocular lens is transferred into the load chamber, the nosepiece is adapted to rotate approximately 180 degrees about the rotational axis between a first position for loading the intraocular lens and a second position for delivering the intraocular lens into the eye.

Abstract: An electrical connector termination assembly includes a dielectric pin holder. A plurality of elongated terminal pins extend through the pin holder in a pattern of at least two rows of pins with the pins in the respective rows being aligned transversely of the rows. Each of at least some of the terminal pins defining a longitudinal axis and including an arm at a termination end of the pin offset from the longitudinal axis. The arm is bent to define a termination pad extending transversely of the longitudinal axis.