Patents by Inventor Mark A. Wood

Mark A. Wood has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240066216
    Abstract: A fluid delivery device has a syringe barrel with reservoir chamber for fluid, a plunger that translates along a longitudinal axis to expel fluid, and a pusher dimensioned to translate within the barrel and coupled to a drive mechanism to controllably contact and move the plunger. The pusher contacts the plunger at its mechanical center to reduce tilt in the plunger. Contact faces of the pusher and plunger cooperate as a ball joint to minimize non-axial forces on the plunger face. The pusher can have a protrusion of various lengths extending toward and being at least partially received in a recess of various depths in the plunger. The pusher is rigidly connected to a drive mechanism for anti-rotation. The pusher can have scalloped edges for air venting, and apertures for cooperating with protrusions on the drive mechanism to prevent bottoming out the plunger when filling.
    Type: Application
    Filed: December 28, 2021
    Publication date: February 29, 2024
    Applicant: Becton, Dickinson and Company
    Inventors: Alessandro PIZZOCHERO, Mark WOOD, Nicholas ANDERSON
  • Patent number: 11896672
    Abstract: The invention provides conjugates that comprise a targeting moiety, a nucleic acid, and optional linking groups as well as synthetic intermediates and synthetic methods useful for preparing the conjugates. The conjugates are useful to target therapeutic nucleic acids to the liver and to treat liver diseases including hepatitis (e.g. hepatitis B and hepatitis D).
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: February 13, 2024
    Assignee: ARBUTUS BIOPHARMA CORPORATION
    Inventors: James Heyes, Richard J. Holland, Alan D. Martin, Mark Wood
  • Patent number: 11857020
    Abstract: A collapsible protective helmet (10) comprises an impact-resistant base body (11) intended to encircle the head of a wearer and an impact-resistant crown (12) coupled to the base body by coupling means to be movable between a protective position in which the crown is supported by the base body in an orientation in which the crown covers the top of the head of the wearer and a stored position inverted relative to the protective position in which the crown is supported by, but nested in, the base body. The helmet further comprises releasable locking means for locking the base body (11) and crown (12) together in each of the two positions of the crown.
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: January 2, 2024
    Inventors: Josh Sam Cohen, Nicolas Dominic Cotton, William Mark Wood
  • Publication number: 20230384063
    Abstract: A waterbody access barrier system has one or more floating barrier segments, and a first floating gate segment for blocking an opening in the barrier system. The first floating gate segment has a latching system to connect it to a capture gear, which is at a fixed barrier termination point or on a second floating gate segment. One or more thrusters are mounted on at least the first floating gate segment. The latching system, and the thrusters, are autonomously or semi-autonomously controlled by a control system, which receives positional signals, for example from a global positioning system (GPS) and/or a light detection and ranging system (LiDAR) operatively connected to the first floating gate segment, and moves the first floating gate segment accordingly.
    Type: Application
    Filed: October 18, 2021
    Publication date: November 30, 2023
    Inventors: Erick Knezek, Matthew Marcy, Mark Wood, David Delleart, William Newton Seelig, Christopher Pacheco
  • Publication number: 20230381407
    Abstract: A delivery device for delivering medicament, such as insulin, to a patient includes a housing and a base enclosing an inner cavity. Enclosed within the housing is a reservoir for containing a medicament, a delivery mechanism for delivering the medicament to the patient, and a pump in fluid communication with the reservoir and delivery mechanism. The base has an integrally formed fluid channel covered by a flexible membrane in fluid communication with the reservoir and the delivery mechanism. A peristaltic pump mechanism includes a cam assembly having a plurality of cams and cam follower assembly with a plurality of protrusions to sequentially engaging the flexible membrane to advance the fluid through fluid channel.
    Type: Application
    Filed: October 5, 2021
    Publication date: November 30, 2023
    Applicant: Becton, Dickinson and Company
    Inventors: Bo Yang YU, Alessandro PIZZOCHERO, J. Richard GYORY, Mark WOOD
  • Publication number: 20230366386
    Abstract: A rotary pump for a fluid metering system is provided. The rotary pump reciprocates, and is reversed by a signal from a limit switch that is deflected by an actuator arm on a rotating sleeve of the pump system. The sleeve receives a gasket that forms a seal between the sleeve and the housing, the gasket having an opening surrounding a side hole of the sleeve to permit fluid to pass through the side hole between a pump volume and an inlet port or outlet port of the housing.
    Type: Application
    Filed: September 29, 2021
    Publication date: November 16, 2023
    Applicant: Becton, Dickinson and Company
    Inventors: Russell COLE, Dan NOLAN, Mark WOOD
  • Patent number: 11787124
    Abstract: An apparatus and related methods for constructing articles with cured pressure-sensitive adhesives comprising (i) a coater that applies a curable adhesive to a membrane; (ii) a cross-linking apparatus adapted to receive said membrane with said curable adhesive, said cross-linking apparatus comprising a light source positioned a first predetermined height above an aperture plate having an aperture therethrough, wherein said aperture plate is positioned a second predetermined height, said first predetermined height and said second predetermined height selected to define an exposure area of light emitted from said light source on to said curable adhesive to form a composite product; and (iii) a roll adapted to receive said composite product, said roll adapted to control a speed at which said membrane with said curable adhesive is exposed to light from said light source.
    Type: Grant
    Filed: June 21, 2022
    Date of Patent: October 17, 2023
    Assignee: Holcim Technology Ltd
    Inventors: Jiansheng Tang, Carl E. Watkins, Jr., Charles Harville, Mark Wood, Joseph Carr
  • Patent number: 11759610
    Abstract: Aspects of articulating devices and methods are disclosed. An exemplary articulating device may comprise an interior core with a reinforcing extending along a central axis, an exterior layer bonded to the interior core by an interface, and a lumen extending through the exterior layer, exterior of the reinforcing element, and parallel to the central axis. A steering wire may be moveable in the lumen to articulate a distal end of the device relative to the central axis in response to a force applied to the steering wire. Related methods of manufacturing an articulating device are also described.
    Type: Grant
    Filed: July 9, 2020
    Date of Patent: September 19, 2023
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Andrew Calabrese, Brian Gaffney, Gene Storbeck, Mark Wood
  • Publication number: 20230285663
    Abstract: Medication delivery system including a container, reservoir, or chamber for medium or fluid, and a mechanism or driving components configurable outside of medium or fluid chamber for advancing a plunger to dispense medium or fluid. The system can include syringe-style drug container, reservoir, or chamber, containing medium or fluid dispensable by advancing plunger disposed inside the container, where the container includes a sliceable portion and where a cutter or slicer is configurable on plunger holder or pusher behind plunger such that cutter cuts through sliceable portion of container as plunger is advanced dispensing medium out of container. The present disclosure is further directed to a patch pump comprising the system as described above. The present disclosure is further directed to a medicament delivery device comprising the system as described above.
    Type: Application
    Filed: August 5, 2021
    Publication date: September 14, 2023
    Applicant: Becton, Dickinson and Company
    Inventors: Nitish Kumar Varma Kunaparaju, Mark Wood, Dan Yasevac, Khodabakhsh Saeedi
  • Publication number: 20230165973
    Abstract: The present invention provides compositions comprising mRNA molecules encapsulated within lipid particles. The lipid particles comprise a cationic lipid, a non-cationic lipid, and an mRNA molecule that is encapsulated within the lipid particle. The compositions are useful, for example, to introduce the mRNA molecules into a human subject where they are translated to produce a polypeptide that functions to ameliorate one or more symptoms of a disease. The invention also provides cationic lipids that are useful for preparing the compositions of the invention.
    Type: Application
    Filed: August 31, 2022
    Publication date: June 1, 2023
    Applicant: ARBUTUS BIOPHARMA CORPORATION
    Inventors: James HEYES, Lorne R. PALMER, Stephen P. REID, Edward D. YAWORSKI, Ian MACLACHLAN, Mark WOOD, Alan D. MARTIN
  • Publication number: 20230110295
    Abstract: The invention provides certain nucleic acids (e.g., double stranded siRNA molecules), as well as conjugates that comprise a targeting moiety, a double stranded siRNA, and optional linking groups. Certain embodiments also provide synthetic methods useful for preparing the conjugates. The conjugates are useful to target therapeutic double stranded siRNA to the liver and to treat liver diseases including hepatitis (e.g. hepatitis B and hepatitis D).
    Type: Application
    Filed: June 30, 2022
    Publication date: April 13, 2023
    Applicant: ARBUTUS BIOPHARMA CORPORATION
    Inventors: James HEYES, Richard J. HOLLAND, Adam JUDGE, Amy C. H. LEE, Alan D. MARTIN, Nicholas Michael SNEAD, Emily P. THI, Mark WOOD, Xin YE
  • Publication number: 20230109183
    Abstract: The present invention provides compositions and methods for the delivery of therapeutic agents to cells. In particular, these include novel, trialkyl, cationic lipids and nucleic acid-lipid particles that provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid to cells in vivo. The compositions of the present invention are highly potent, thereby allowing effective knock-down of a specific target protein at relatively low doses.
    Type: Application
    Filed: June 17, 2022
    Publication date: April 6, 2023
    Applicant: ARBUTUS BIOPHARMA CORPORATION
    Inventors: James Heyes, Mark Wood, Alan Martin
  • Publication number: 20230067085
    Abstract: A pump subsystem for fluid delivery (e.g., in a wearable patch pump) is provided wherein pumping action is generated by linear piston movement that pulls a plug, which is interconnected to the piston between two mechanical extremes or end stops in a telescopic or variable volume fluid chamber. Such interconnection enables piston and plug to move a certain distance with respect to each other that corresponds to a predefined swept volume of the pump subsystem. Telescoping-like effect of relative piston and plug movement provides for intake and discharge of fluid with respect to the fluid chamber. Movement of plug within piston can be enabled by the friction of seals placed on the plug, which serve to provide resistance to piston motion and therefore force translation motion of the plug to lag relative to the piston translation motion during portions of the pump cycle.
    Type: Application
    Filed: January 20, 2021
    Publication date: March 2, 2023
    Applicant: Becton, Dickinson and Company
    Inventors: Alessandro PIZZOCHERO, Mark WOOD, Russell COLE
  • Publication number: 20230064224
    Abstract: Pump subsystem for fluid delivery (e.g., in a wearable patch pump) comprises a fluid chamber with pumping motion and a valve shaft assembly with valving motion, both being driven by the same drive mechanism. Fluid chamber has variable volume chamber provided by a piston driven by the drive mechanism and translated relative to a plug in the pump housing. Piston extends the fluid chamber during an intake stroke and retracts the fluid chamber during a discharge stroke. Valve assembly has at least one valve shaft controllably translated by the drive mechanism to selectively align a first throughway with an opening in the pump chamber and a fluid intake port for an intake stroke to draw fluid into the fluid chamber, and align a second throughway with the opening in the pump hamber and a fluid discharge port for an discharge stroke to discharge fluid from the fluid chamber.
    Type: Application
    Filed: January 20, 2021
    Publication date: March 2, 2023
    Applicant: Becton, Dickinson and Company
    Inventors: Alessandro PIZZOCHERO, Mark WOOD, Shehryar SIDDIQUI, Elizabeth GURIN, Keith KNAPP
  • Publication number: 20230058016
    Abstract: The present disclosure relates to systems and methods for providing cybersecurity functionality to computer implemented inventions such as Internet of Thing (IoT) systems and object devices, and more specifically, to an improved cybersecurity system, method and capabilities for the protecting IoT and similar devices through non-discriminatory vendor/supplier independent distribution of secure predetermined IoT syndication data to unidentified and non-registered IoT devices, through the use of a passive data distribution technology and out-of-band, system-to-device distribution channel and no peer-to-peer stateless relationship with the receiving device and using Quality of Service (QoS) and enabling the determination as to whether there is any suspicious activity occurring and prohibiting the IoT device from taking any customer-defined action without have a separately provided authentication.
    Type: Application
    Filed: October 20, 2022
    Publication date: February 23, 2023
    Inventors: Mark Wood, Claudia Bitner, Art Deacon, Elysa Jones, Matt Walton
  • Publication number: 20220387600
    Abstract: Provided herein are certain nucleic acids (e.g., double stranded siRNA molecules), as well as conjugates that comprise a targeting moiety, a double stranded siRNA, and optional linking groups. Certain embodiments also provide synthetic methods useful for preparing the conjugates. The conjugates are useful to treat certain diseases, such as liver fibrosis, e.g., in the setting of NASH or ASH.
    Type: Application
    Filed: December 7, 2020
    Publication date: December 8, 2022
    Applicant: GENEVANT SCIENCES GMBH
    Inventors: James HEYES, Richard J. HOLLAND, Mark WOOD, Alan D. MARTIN, Christine ESAU, Margrit SCHWARZ, Xin YE, Alice Hoy Lam LI, Christopher Justin PASETKA, David CROWE, Steven TYLER
  • Patent number: 11504102
    Abstract: This invention is directed to a medical device having an elongate shaft having a distal end and a controller coupled to the shaft. A control member can extend through at least part of the elongate shaft and at least part of the controller, wherein the control member in a tensioned configuration can be moveable by the controller to control the distal end of the shaft and the control member can be slack in an untensioned configuration. A tensioning mechanism can be configured to move relative to at least one of the elongate shaft and the controller to tension the control member and automatically lock the control member in the tensioned configuration.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: November 22, 2022
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Larry Stanton, John Golden, Gary Kappel, Mark Wood, Bernadette Durr, Brandon Zalewski, Ken Keene, Barry Weitzner, Paul Smith, Naroun Suon
  • Publication number: 20220314555
    Abstract: An apparatus and related methods for constructing articles with cured pressure-sensitive adhesives comprising (i) a coater that applies a curable adhesive to a membrane; (ii) a cross-linking apparatus adapted to receive said membrane with said curable adhesive, said cross-linking apparatus comprising a light source positioned a first predetermined height above an aperture plate having an aperture therethrough, wherein said aperture plate is positioned a second predetermined height, said first predetermined height and said second predetermined height selected to define an exposure area of light emitted from said light source on to said curable adhesive to form a composite product; and (iii) a roll adapted to receive said composite product, said roll adapted to control a speed at which said membrane with said curable adhesive is exposed to light from said light source.
    Type: Application
    Filed: June 21, 2022
    Publication date: October 6, 2022
    Inventors: Jiansheng TANG, Carl E. WATKINS, JR., Charles HARVILLE, Mark WOOD, Joseph CARR
  • Publication number: 20220288214
    Abstract: Provided herein are certain nucleic acids (e.g., double stranded siRNA molecules), as well as conjugates that comprise a targeting moiety, a double stranded siRNA, and optional linking groups. Certain embodiments also provide synthetic methods useful for preparing the conjugates. He conjugates are useful to treat certain diseases, such as acromegaly.
    Type: Application
    Filed: October 23, 2020
    Publication date: September 15, 2022
    Applicant: GENEVANT SCIENCES GMBH
    Inventors: Drew KONDRATOWICZ, James HEYES, Richard J. HOLLAND, Christine ESAU, Kevin MCCLINTOCK, Christopher Justin PASETKA, Mark WOOD, Alan D. MARTIN, Margrit SCHWARZ, David CROWE, Steven TYLER
  • Patent number: 11427823
    Abstract: The invention provides certain nucleic acids (e.g., double stranded siRNA molecules), as well as conjugates that comprise a targeting moiety, a double stranded siRNA, and optional linking groups. Certain embodiments also provide synthetic methods useful for preparing the conjugates. The conjugates are useful to target therapeutic double stranded siRNA to the liver and to treat liver diseases including hepatitis (e.g. hepatitis B and hepatitis D).
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: August 30, 2022
    Assignee: ARBUTUS BIOPHARMA CORPORATION
    Inventors: James Heyes, Richard J. Holland, Adam Judge, Amy C. H. Lee, Alan D. Martin, Nicholas Michael Snead, Emily P. Thi, Mark Wood, Xin Ye