Abstract: A method of mass spectrometry is disclosed comprising passing ions through an ion mobility spectrometer and acquiring first ion mobility drift time data. A calibration function is applied to the first ion mobility drift time data to determine a physico-chemical property (e.g. CCS) of the ions. Second ion mobility drift time data is then acquired and the calibration function is applied to the second ion mobility drift time data to determine the physico-chemical property of one or more known or reference ions. The calibration function is then adjusted.

Abstract: A mass spectrometer is disclosed comprising a glow discharge device within the initial vacuum chamber of the mass spectrometer. The glow discharge device may comprise a tubular electrode (14) located within an isolation valve (15) which is provided in the vacuum chamber. Reagent vapor may be provided through the tubular electrode (14) which is then subsequently ionized by the glow discharge. The resulting reagent ions may be used for Electron Transfer Dissociation of analyte ions generated by an atmospheric pressure ion source. Other embodiments are contemplated wherein the ions generated by the glow discharge device may be used to reduce the charge state of analyte ions by Proton Transfer Reaction or may act as lock mass or reference ions.

Abstract: An ion-ion reaction cell is provided comprising a plurality of electrodes forming an ion guide. A transient DC voltage wave is applied to the electrodes in order to load reagent anions into the ion guide. Analyte cations are then subsequently transmitted through the ion-ion reaction cell by a subsequent transient DC voltage wave. Ion are arranged to undergo ion-ion reactions within the reaction cell and the resulting fragment ions which are formed within the reaction cell are then subsequently translated out of the reaction cell by means of a transient DC voltage wave.

Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.

Abstract: A mass spectrometer is disclosed comprising a RF confinement device, a beam expander and a Time of Flight mass analyzer. The beam expander is arranged to expand an ion beam emerging from the RF confinement device so that the ion beam is expanded to a diameter of at least 3 mm in the orthogonal acceleration extraction region of the Time of Flight mass analyzer.

Abstract: A mass spectrometer is disclosed comprising a cooling cell 4 for cooling ions so as to reduce their kinetic energy. The cooling cell 4 comprises: a chamber for receiving the ions or for generating the ions therein, wherein said chamber is formed from walls defining a substantially enclosed region; and a cooling jacket 16 surrounding said chamber, wherein said cooling jacket 16 is arranged and configured to contain a cooling fluid and so as to remove heat from one or more walls of the chamber. The mass spectrometer further comprises a mass analyser 6 for receiving ions from the cooling cell 4 after they have been cooled. The present invention reduced the kinetic energy of the ions prior to mass analysis and hence improves the resolution of the mass analyser 6. The mass analyser is preferably a time of flight mass analyser.

Abstract: Electronic devices may be provided with compasses for detecting the Earth's magnetic field. Electronic devices may be provided with electronic components that generate interfering magnetic fields for the compass. Electronic components may be coupled between a power supply line and a power return line on a printed circuit. The power return line may be configured to generate a compensating magnetic field to counteract the interfering magnetic fields. The power return line may be formed parallel to the power supply line. The power supply line may have multiple branches equidistant from the compass. The power return line may have a portion closer to the compass than the power supply line and the electronic component. The power return line may have multiple branches, may be provided with resistors on each branch and may include a portion of a circular loop the runs around the compass on the printed circuit board.

Abstract: A method of mass spectrometry is disclosed comprising alternating between a first mode in which parent ions are mass analysed and a second mode in which the parent ions are subjected to Electron Capture Dissociation (“ECD”) at atmospheric pressure so as to produce fragment ions which are then mass analysed. The parent ions are associated with their fragment ions based on the times at which they were detected. This method enables parent ions to be associated with their fragment ions, even when the ECD fragmentation is performed at atmospheric pressure.

Abstract: We disclose a monovinylarene-conjugated diene block copolymer containing a plurality of monovinylarene-conjugated diene mixed blocks, wherein each mixed block contains conjugated diene units and monovinylarene units in a weight ratio of about 0.05 to about 0.33. We also disclose a composition containing (a) from about 50 parts by weight to about 95 parts by weight of the monovinylarene-conjugated diene block copolymer and (b) from about 5 parts by weight to about 50 parts by weight of polystyrene; wherein the monovinylarene-conjugated diene block copolymer and the polystyrene total 100 parts by weight.

Abstract: A mass spectrometer is disclosed comprising an RF ion guide or ion trap and a device arranged and adapted to supply a reagent gas within the RF ion guide or ion trap. The mass spectrometer further comprises a photo-ionisation device and a control system arranged and adapted: (i) to cause first ions to fragment or dissociate within the RF ion guide or ion trap to form second ions and neutral molecules; and (ii) to cause the photo-ionisation device to photo-ionise and/or photo-excite the reagent gas to form reagent ions, excited species or radical species. The reagent ions, excited species or radical species interact with at least some of the neutral molecules located within the RF ion guide or ion trap to form analyte ions.

Abstract: A method of mass spectrometry is disclosed comprising alternating between a first mode in which parent ions are analysed and a second mode in which parent ions are fragmented and their fragment ions are mass analysed. In the first mode the parent ions are charge reduced before being analysed, so as to simplify the parent ion spectral data obtained. In the second mode, the parent ions are not charge reduced prior to fragmentation, so that it remains relatively easy to induce the parent ions to fragment. The parent ions are then associated with their fragment ions using the mass spectral data obtained.

Abstract: A method of mass spectrometry is disclosed comprising passing ions through an ion mobility spectrometer and acquiring first ion mobility drift time data. A calibration function is applied to the first ion mobility drift time data to determine a physico-chemical property (e.g. CCS) of the ions. Second ion mobility drift time data is then acquired and the calibration function is applied to the second ion mobility drift time data to determine the physico-chemical property of one or more known or reference ions.

Abstract: A wheel spindle drive element for a wheel disconnect system. The wheel spindle assembling onto an outer diameter of a spindle, displacing material to form a joint with high torque transmission characteristics.

Abstract: A wheel spindle drive element for a wheel disconnect system. The wheel spindle assembling onto an outer diameter of a spindle, displacing material to form a joint with high torque transmission characteristics.

Abstract: A mass spectrometer is disclosed comprising a hydrogen-deuterium exchange cell. Isomeric ions having different conformations but substantially similar ion mobilities can be differentiated by subjecting the ions to hydrogen-deuterium exchange. Two ions having similar ion mobilities can be differentiated more effectively if they have different surface conformations by determining the relative degree of hydrogen-deuterium exchange.

Abstract: A method of mass spectrometry is disclosed comprising providing a mixture of different analyte ions and supplying electrons or reagent ions to said mixture so as to transfer charge to the analyte ions. The transfer of charge causes at least some of the analyte ions to dissociate and others of the analyte ions not to dissociate, but to form intermediate ions of altered charge state. These intermediate ions are then isolated from other ions and excited so as to dissociate into daughter ions. The intermediate ions and their daughter ions are analysed and associated with each other so that the intermediate can be identified from their daughter ions. The analyte ions can then be identified from the intermediate ions, since they differ only in charge state. The disclosed method enables analyte ions to be associated with their fragment ions, and therefore identified, without having to isolate individual analyte ions prior to their interactions with the electrons or reagent ions.

Abstract: An order picker has a body section with a pair of ground engaging wheels and a first lift mechanism pivotally mounted to one end of the body section about a vertical pivot and one or more ground engaging wheels is/are provided on the first lift mechanism. A mechanism is provided for pivoting the first lift mechanism relative to the body section whereby the order picker may be steered. An open cab is provided on the body section whereby an operative may have access to stacks on either side of the order picker. The cab is mounted to the body section on a second lift mechanism by which the cab may be raised and lowered with respect to the body section independently of the first lift mechanism. A receptacle onto or into which picked items may be placed, the receptacle is mounted on the cab on the end thereof remote from the end of the body section to which the first lift mechanism is mounted.

Abstract: A rolling element guide for a bearing assembly formed with cantilevered arms, the arms flexibly adjusting to contact with a guide surface of an inner or outer ring of a bearing. Lubrication channels in a surface of the cage are also disclosed.

Abstract: The invention relates to an aluminum alloy lithographic sheet product having an enhanced electrolytic graining response in which Zn between 0.5 and 2.5 wt % is added to an aluminum base alloy, in particular an alloy of the 1XXX, 3XXX or 5XXX series alloys. The invention also relates to a method of producing a lithographic sheet product.

Abstract: An ion source for a mass spectrometer is disclosed comprising a lens and mirror arrangement which focuses a laser beam onto the upper surface of a target substrate. The lens has an effective focal length ?300 mm. The laser beam is directed onto the target substrate at an angle ? with respect to the perpendicular to the target substrate, wherein ??3°. One or more ion guides receive ions released from the target substrate and onwardly transmit the ions along an ion path which substantially bypasses the lens and mirror.