Abstract: A method of processing audio data for replay on a mobile device with a first speaker and a second speaker, wherein the audio data comprises a respective audio signal for each of the first and second speakers, includes: determining a device orientation of the mobile device; if the determined device orientation is vertical orientation, applying a first processing mode to the audio signals for the first and second speakers; and if the determined device orientation is horizontal orientation, applying a second processing mode to the audio signals for the first and second speakers.

Abstract: A key integrates with a biometric input device. According to an aspect of the present disclosure, a fingerprint scanner may be integral with a spacebar.

Abstract: The specification relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof, where Q, R, R1 and R2 have any of the meanings defined herein. The specification also relates to the use of such compounds and salts thereof to treat or prevent GLS1 mediated disease, including cancer. The specification further relates to crystalline forms of compounds of Formula (I) and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds and salts; kits comprising such compounds and salts; methods of manufacture of such compounds and salts; intermediates useful in the manufacture of such compounds and salts; and to methods of treating GLS1 kinase mediated disease, including cancer, using such compounds and salts.

Abstract: An organomodified silicone material is shown and described herein. The organomodified silicone provides a material that can be used as an additive in a fuel oil, e.g., diesel fuel. The organomodified silicone acts as both a defoamer and a dehazer in a fuel oil.

Abstract: An assembly includes a first vane pack, a second vane pack, and a liner lock segment. The first vane pack has a plurality of vanes each vane with an airfoil, a platform, and forward and aft mounting hooks. The second vane pack has a plurality of vanes each vane with an airfoil, a platform, and forward and aft mounting hooks. The second vane pack is disposed to abut the first vane pack. The liner lock segment is disposed between the first vane pack and the second vane pack.

Abstract: Systems and methods provide customizable insurance according to consumer preferences and attributes. An enhanced attributes analysis server may analyze the attributes of a consumer and match these attributes with attributes of current customers of an entity managing the server. The insurance products/plans preferred by the matched customers may then be used to present insurance options to the consumer. In addition, the server may further customize insurance options based on answers to questions that relate to the consumer's specific situation. Further still, the consumer's social network may be used to understand insurance products/plans that may be preferred by the consumer.

Abstract: A system comprises a number of master devices and an interconnect for managing coherency between the master devices. In response to a read-with-overridable-invalidate transaction received by the interconnect from a requesting master device requesting that target data associated with a target address is provided to the requesting master device, when target data associated with the target address is stored by a cache, the interconnect issues a snoop request to said cache triggering invalidation of the target data from the cache except when the interconnect or cache determines to override the invalidation and retain the target data in the cache. This enables greater efficiency in cache usage since data which the requesting master considers is unlikely to be needed again can be invalidated from caches located outside the master device itself.

Abstract: The invention relates to an actuatable compact vehicle step with first and second step portions that bifurcate from a single axis when moving from nested to extended positions to provide two or more tiered steps, the second step in a position substantially below the first step when deployed. In various embodiments, step portions travel on curved tracks from the nested position to allow them to be both well-concealed when nested and optimally extended when deployed.

Abstract: The present invention relates to compounds, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, for example as inhibitors of the activity of RIP2 kinase, including degrading RIP2 kinase, the treatment of diseases and conditions mediated by the RIP2 kinase, in particular for the treatment of inflammatory diseases or conditions.

Abstract: A resource management and task allocation controller for installation in a multicore processor having a plurality of interconnected processor elements providing resources for processing executable transactions, at least one of said elements being a master processing unit, the controller being adapted to communicate, when installed, with each of the processor elements including the master processing unit, and comprising control logic for allocating executable transactions within the multicore processor to particular processor elements in accordance with pre-defined allocation parameters.

Abstract: This invention relates to compounds that are agonists of the muscarinic M1 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds include those according to formula 1, or a salt thereof wherein Q, R1, R2, R3 and R4 are as defined herein.

Abstract: According to various embodiments, a method for providing task related information to a user may be provided. The method may include: determining location information based on a spatial model; determining task information based on a task model; determining sensor information; determining output information based on the location information, task information and sensor information; and providing the output information to the user. In a specific embodiment, the output information may comprise an orientation cue, an error indication or a contextual cue to assist the user in performing the task associated with the location detected by a vision recognition method, and the output information can be provided to the user as augmented reality in a wearable device.

Abstract: This invention relates to oral veterinary compositions for combating ectoparasites and endoparasites in animals, comprising at least one systemically-acting active agent in combination with a pharmaceutically acceptable carrier. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.

Abstract: Devices and methods are provided for injection of a therapeutic agent into an area beneath eye tissue, such as a sub-retinal area or a suprachoroidal area. Example devices comprise an injector housing, a tubular element (needle or microcatheter), a first area within the injector housing configured to be selectively in fluid communication with the tubular element for delivery of a bleb-formation fluid, and a second area within the injector housing configured to be selectively in fluid communication with the tubular element for delivery of a therapeutic agent into the area beneath eye tissue. In some embodiments, the first area is a chamber within the injector housing, and the second area is an internal area of a tube within the chamber. The devices and methods allow, with a single needle (or microcatheter) insertion, high pressure bleb formation and low pressure delivery of fragile therapeutic agent compositions.

Abstract: Methods and apparatus that mix a plurality of individual capture reagents for the diagnostic assays are described herein. In an embodiment, a system for optically analyzing a patient sample includes an automated immunochemistry analyzer storing a plurality of capture reagents and a plurality of paramagnetic particles, a user interface configured to allow a selection of a combination of two or more of the capture reagents, and a logic implementer configured to cause the automated immunochemistry analyzer to (i) mix together each capture reagent of the combination of two or more of the capture reagents; (ii) bind the mixture of the combination of two or more of the capture reagents to the paramagnetic particles; (iii) bind the patient sample to the bound mixture of the combination of two or more of the capture reagents; and (iv) optically analyze the patient sample.

Abstract: A method for creating a welded joint between ends of two steel rails, wherein the two steel rails have a substantially pearlitic microstructure. The method includes a first heating step, an upsetting step, a first cooling step, and a second heating step and provides a means to influence a microstructure and hardness of an austenitic region of a heat affected zone (HAZ) and/or an extent of softening in a softened region of a HAZ.

Abstract: Sharing a bundle. A method includes identifying a bundle defined by a first user. The bundle includes a number of portions. One or more portions are configured to provide data from a data source. The method further includes identifying within the bundle one or more portions of the bundle that can be changed when the bundle is consumed by other users. The method further includes modifying the identified portions before the bundle is consumed by other users.

Abstract: A cooling system for cooling air in a rack mounted equipment such as computer systems. The cooling system includes a split and staggered cooling system where the cooling is carried out by two different parallel coolers. One of the coolers is pressed against the walls of the cooling duct, but allows some amount of the air to pass around the cooler. The output of that first cooler is also constricted to a similar amount as the air output that passes around the first cooler. The second cooler is downstream of the first cooler, and receives all the air that passes around the first cooler and provides cooling to that air. In this way, two different split coolers can be used to cool the air stream.

Abstract: A utility meter includes a meter housing in which are supported at least one current coil, a temperature sensor, and a processing circuit. The current coil can be coupled to receive heat energy from within or on the meter socket. The temperature sensor generates a sensor signal based on a temperature within the meter housing. The processing circuit is operably coupled to the temperature sensor and the at least one current coil. The processing circuit obtains the sensor signal and generates temperature information therefrom, and also generates measurements of current through the current coil. The processing circuit generates an adjustment based at least on the square of the measured current, and determines whether an abnormal condition exists based on the temperature information, the adjustment, and a threshold. The processing circuit can generate an output signal to a display or communication circuit responsive to determining that the abnormal condition exists.