Abstract: The instant invention provides compounds of formula I which are JAK3 inhibitors. Specifically, the compounds of formula I are pyrrolo[2,3-d]pyrimidine derivative compounds. The instant invention also provides methods of treating JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer, by administering the pyrrolo[2,3-d]pyrimidine-derivative compounds of formula I.

Abstract: The instant invention provides compounds of formula I which are Jak inhibitors, and as such are useful for the treatment of Jak-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

Abstract: The instant invention provides compounds of formula I which are JAK3 inhibitors. Specifically, the compounds of formula I are pyrrolo[2,3-d]pyrimidine derivative compounds. The instant invention also provides methods of treating JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer, by administering the pyrrolo[2,3-d]pyrimidine-derivative compounds of formula I.

Abstract: Embodiments of techniques and systems associated with roots-of-trust (RTMs) for measurement of virtual machines (VMs) are disclosed. In some embodiments, a computing platform may provide a virtual machine RTM (vRTM) in a first secure enclave of the computing platform. The computing platform may be configured to perform an integrity measurement of the first secure enclave. The computing platform may provide a virtual machine trusted platform module (vTPM), for a guest VM, outside the first secure enclave of the computing platform. The computing platform may initiate a chain of integrity measurements between the vRTM and a resource of the guest VM. Other embodiments may be described and/or claimed.

Abstract: An anti-malware approach uses a storage drive with the capability to lock selected memory areas. Platform assets such as OS objects are stored in the locked areas and thus, unauthorized changes to them may not be made by an anti-malware entity.

Abstract: The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of ?3-adrenoceptor.

Abstract: The instant invention provides compounds of formula I which are Jak inhibitors, and as such are useful for the treatment of Jak-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

Abstract: The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of ?3-adrenoceptor.

Abstract: An anti-malware approach uses a storage drive with the capability to lock selected memory areas. Platform assets such as OS objects are stored in the locked areas and thus, unauthorized changes to them may not be made by an anti-malware entity.

Abstract: A method and system to allow encryption/decryption to be performed substantially in parallel using one or more media associated keys. The system has an input buffer to store a plurality of media data from a plurality of media channels. A plurality of cryptographic engines is coupled with the input buffer to obtain a plurality of cipher keys and each cipher key is associated with one or more of a plurality of media channels The system encrypts or decrypts, substantially in parallel, each of the plurality of media data with a cryptographic algorithm using one or more of the obtained cipher keys.

Abstract: A method and related system to determine nasal resistance to airflow. Some of the exemplary embodiments may be a method comprising measuring an attribute of airflow through a first naris of a patient without blocking a second naris of the patient, measuring an attribute of airflow through the second naris of the patient without blocking the first naris, and determining a value indicative of nasal resistance to airflow based on the attributes measured.

Abstract: An apparatus for reinflating an object such as a punctured automobile tire. The apparatus including a valve assembly having a housing with two inputs which are connected to an outlet through passageways within the housing. A valve is provided such that the input passageway which receives the output from a compressed air source is connected, in its normal position, to the outlet of the housing for connection to an automobile tire or inflatable object. The second input to the valve assembly is opened by placing the valve in the second position. The second position of the valve closes the first input from the compressor to the outlet and seals the first input from the second input. The second input includes a threaded fitting on an aerosol type can which seals the input to the housing as well as it seals with respect to the can to which it is attached.

Abstract: A tubular nozzle housing having one end secured to a pressurized container supports a reciprocable actuator for selectively actuating a discharge valve on the container when the opposite end of the nozzle housing is threaded to means for receiving the pressured contents of said container.