Abstract: A composite scaffold having a highly porous interior with increased surface area and void volume is surrounded by a flexible support structure that substantially maintains its three-dimensional shape under tension and provides mechanical reinforcement during repair or reconstruction of soft tissue while simultaneously facilitating regeneration of functional tissue.

Abstract: Methods and systems for using machine learning models to organize and select modular components for user interface templates. For example, the methods and systems may use machine learning and/or artificial intelligence to generate user interfaces with a preferred number of user input fields and/or pages, in which the preferred number both satisfies any requirements for the user interface (e.g., information, categories of information, etc.), and ensures that all privacy concerns are met.

Abstract: The present invention comprises conjugates comprising a glucagon-like peptide 1 (GLP-1) fusion peptide coupled to a cyclic PYY peptide. The invention also relates to pharmaceutical compositions and methods for use thereof. The novel conjugates are useful for preventing, treating or ameliorating diseases and disorders disclosed herein.

Abstract: A diagnostic circuit includes an input port configured to receive an input current and a first superconducting quantum interference device (SQUID) inductively coupled to the input port. The first SQUID is configured to generate a first output in the form of: a first voltage in response to the input current being less than a first threshold current and a second voltage in response to the input current being greater than the first threshold current. The diagnostic circuit also includes a second SQUID inductively coupled to the input port. The second SQUID is configured to generate a second output in the form of: a third voltage in response to the input current being less than a second threshold current and a fourth voltage in response to the input current being greater than the second threshold current.

Abstract: Systems, method and computer readable medium are provided for automated storage and retrieval. User authentication information is received via a user interface for a dynamic storage and retrieval device. The user identity is verified based upon the authentication information and previously stored authentication data. Order information is retrieved for an order associated with the user following the verifying of user identity, the order information indicating one or more locations for items associated with the order. Instructions are transmitted to initiate a physical opening of at least one of the dynamic storage and retrieval device and at least one static storage location to enable the user to retrieve at least one item of the order, the static storage location including a controller controlling a locking mechanism and communicatively coupled to the dynamic storage and retrieval device.

Abstract: A computer-implemented method of fraud protection is described. A server may receive one or more keywords and a likelihood of fraud from an external source. The server may receive an image of a document from a user device, wherein the document comprises at least one of a written communication or a printed communication. The server may extract text from the image of the document, compare the extracted text to the one or more stored keywords, and calculate a confidence level of fraud. The server may send an indication of the confidence level of fraud to the user device.

Abstract: An accessory for use with a portable container includes a jacket configured to extend around at least a portion of the sidewall of the container, the jacket including a plurality of modular sections formed separately and connected together around the at least a portion of the sidewall of the container. The modular sections include a first modular section having extending around a first portion of the sidewall of the container, a second modular section connected to the first modular section and extending around a second portion of the sidewall of the container, and at least one additional modular section extending around a third portion of the sidewall of the container. The first and second modular sections have different structural configurations. The accessory also includes a first connection member connected to the jacket and configured to support the jacket in connection with the container.

Abstract: In one aspect, the invention relates to an immunogenic composition that includes a mutant Clostridium difficile toxin A and/or a mutant Clostridium difficile toxin B. The mutant toxin may include a glucosyltransferase domain having at least one mutation and a cysteine protease domain having at least one mutation, relative to the corresponding wild-type C. difficile toxin. The mutant toxins may include at least one amino acid that is chemically crosslinked. In another aspect, the invention relates to methods and compositions for use in culturing Clostridium difficile and in producing C. difficile toxins.

Abstract: Paper towel rolls that exhibit novel combinations of physical properties, such as Basis Weight, Roll Density, and Roll Diameter, such that the paper towel rolls meet consumers' needs, and method for making such novel paper towel rolls and marketing such novel paper towel rolls are provided.

Abstract: An exposed secondary showerhead system configured to be supported by a conventional shower enclosure. The illustrative showerhead system includes an overhead conduit fluidly coupled to a conventional shower inlet pipe and to at least one showerhead.

Abstract: There is provided a fan assembly comprising a motor-driven impeller arranged to generate an airflow, an air outlet arranged to emit the airflow, a plurality of sensors arranged to measure a value for each of a plurality of air quality characteristics, a display and a processor. The processor is configured to receive measured values for each of the plurality of air quality characteristics, identify one of a corresponding set of intervals within which the measured value falls and select an air quality index value associated with the identified interval. The processor is then configured to identify the highest of the selected air quality index values as a current overall air quality index value and to cause the display to display a time series plot of the current air quality index value and a number of preceding air quality index values.

Abstract: An aqueous colored pigment-based ink that is capable of fluorescence, has a pigment colorant in an amount of 1-7 weight %; a non-polymeric fluorophore that when excited by fluorescence-exciting radiation having a peak of at least 200 nm and up to and including 400 nm, exhibits an emission peak of at least 400 nm and up to and including 750 nm, and which non-polymeric fluorophore is present in an amount of 0.1-2 weight %; and an aqueous medium comprising water. This aqueous colored pigment-based ink can be included in an ink set that also includes one or more aqueous colored pigment-based inks that are non-fluorescent. All of these inks can be applied using continuous inkjet (CIJ) printing, onto non-UV fluorescent substrates to provide images that can be detected when excited as noted above, which images can be provided on articles such as security documents, currency, and lottery tickets.

Abstract: System and devices for live captioning events is disclosed. The system may receive event calendar data and a first plurality of caption files and preselect a first caption file based on the event calendar data. The system may then access an audiovisual recorder of a user device, and receive a first feedback from the recorder. The system may then determine whether the first caption file matches the first feedback. When there is a match, the system may determine a first synchronization between the caption file and the feedback. When there is no match, the system may determine if there is a match with a second caption file of the first plurality of caption files and determine a second synchronization. When the second caption file does not match, the system may receive at least a third caption file over a mobile network and determine a third synchronization for display.

Abstract: In some illustrative examples, a bridge suitable for treating a tissue site may include a bridge sealing member and one or more bridge wicking layers. The bridge sealing member may extend along a length of the bridge, and may define an internal passageway in fluid communication between a receiving end of the bridge and a transmitting end of the bridge. The one or more bridge wicking layers may be disposed within the internal passageway of the bridge sealing member. Other apparatus, systems, and methods are disclosed.

Abstract: An aqueous colored pigment-based ink that is capable of fluorescence, has a pigment colorant in an amount of 1-7 weight %; a non-polymeric fluorophore that when excited by fluorescence-exciting radiation having a peak of at least 200 nm and up to and including 400 nm, exhibits an emission peak of at least 400 nm and up to and including 750 nm, and which non-polymeric fluorophore is present in an amount of 0.1-2 weight %; and an aqueous medium comprising water. This aqueous colored pigment-based ink can be included in an ink set that also includes one or more aqueous colored pigment-based inks that are non-fluorescent. All of these inks can be inkjet printed on non-UV fluorescent substrates to provide images that can be detected when excited as noted above, which images can be provided on documents, lottery tickets, and other security papers.

Abstract: An aqueous colored pigment-based ink that is capable of fluorescence, has a pigment colorant in an amount of 1-7 weight %; a non-polymeric fluorophore that when excited by fluorescence-exciting radiation having a peak of at least 200 nm and up to and including 400 nm, exhibits an emission peak of at least 400 nm and up to and including 750 nm, and which non-polymeric fluorophore is present in an amount of 0.1-2 weight %; and an aqueous medium comprising water. This aqueous colored pigment-based ink can be included in an ink set that also includes one or more aqueous colored pigment-based inks that are non-fluorescent. All of these inks can be applied for example using inkjet printing, onto non-UV fluorescent substrates to provide images that can be detected when excited as noted above, which images can be provided on articles such as security documents, currency, and lottery tickets.

Abstract: A fluorescent colored image can be detected in an image on an article. This fluorescent colored image is obtained from applying an aqueous colored pigment-based ink that is capable of fluorescence, onto a suitable non-UV fluorescent substrate. This aqueous colored pigment-based ink has 1-7 weight % of a pigment colorant; and 0.1-2 weight % of a non-polymeric fluorophore that when excited by fluorescence-exciting radiation having a peak of at least 200 nm and up to and including 400 nm, exhibits an emission peak of at least 400 nm and up to and including 750 nm. This aqueous colored pigment-based ink that is capable of fluorescence can be applied using inkjet printing, onto non-UV fluorescent substrates to provide images that can be detected when excited as noted above, which images can be provided on articles such as security documents, currency, and lottery tickets.

Abstract: According to an aspect, an inflatable penile prosthesis includes a fluid reservoir configured to hold fluid, an inflatable member, and a pump assembly configured to transfer the fluid between the fluid reservoir and the inflatable member. The pump assembly includes a pump bulb, a valve body, a valve disposed within the valve body, a first fluid port configured to be fluidly coupled to the fluid reservoir, and a second fluid port configured to be fluidly coupled to the inflatable member. The valve is configured to move between an inflation position and a deflation position. The valve includes a first member and second member, the first member being configured to move with respect to the second member.

Abstract: Techniques are disclosed herein for objective function optimization in target based hyperparameter tuning. In one aspect, a computer-implemented method is provided that includes initializing a machine learning algorithm with a set of hyperparameter values and obtaining a hyperparameter objective function that comprises a domain score for each domain that is calculated based on a number of instances within an evaluation dataset that are correctly or incorrectly predicted by the machine learning algorithm during a given trial. For each trial of a hyperparameter tuning process: training the machine learning algorithm to generate a machine learning model, running the machine learning model in different domains using the set of hyperparameter values, evaluating the machine learning model for each domain, and once the machine learning model has reached convergence, outputting at least one machine learning model.

Abstract: Techniques are provided for using context tags in named-entity recognition (NER) models. In one particular aspect, a method is provided that includes receiving an utterance, generating embeddings for words of the utterance, generating a regular expression and gazetteer feature vector for the utterance, generating a context tag distribution feature vector for the utterance, concatenating or interpolating the embeddings with the regular expression and gazetteer feature vector and the context tag distribution feature vector to generate a set of feature vectors, generating an encoded form of the utterance based on the set of feature vectors, generating log-probabilities based on the encoded form of the utterance, and identifying one or more constraints for the utterance.