Patents by Inventor Mark Edwards

Mark Edwards has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10975065
    Abstract: The present invention relates to N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamide compounds of Formulae (IA and 1B) or a pharmaceutically acceptable salt or hydrate thereof, that inhibit CC chemokine receptor 6 (CCR6), pharmaceutical compositions containing these compounds, and the use of these compounds for treating or preventing diseases, conditions, or disorders ameliorated by inhibition of CCR6.
    Type: Grant
    Filed: September 20, 2019
    Date of Patent: April 13, 2021
    Assignee: Pfizer Inc.
    Inventors: Brian Stephen Gerstenberger, Andrew Christopher Flick, Vincent Michael Lombardo, James John Mousseau, Philippe Marcel Nuhant, Ralph Pelton Robinson, Jr., Mark Edward Schnute, Daniel Wei-Shung Kung, Daniel Copley Schmitt, Atli Thorarensen, John Isidro Trujillo, Rayomand Jal Unwalla, Huixian Wu
  • Publication number: 20210099670
    Abstract: A system includes a downstream facing port (DFP) coupled to a video source, an upstream facing port (UFP) coupled to a video sink, and a cable. The cable includes a first end that is connected to the DFP and a second end that is connected to the UFP. The cable is configured to carry a differential auxiliary transmission signal and detect polarity in the differential auxiliary transmission signal.
    Type: Application
    Filed: December 10, 2020
    Publication date: April 1, 2021
    Inventors: Charles Michael CAMPBELL, Anwar SADAT, Mark Edward WENTROBLE
  • Publication number: 20210087357
    Abstract: An additive article stabilizing method includes prior to polymerization, adding a radiation-activated stabilizing composition to a liquid resin, forming the article from the liquid resin, layer by layer, using radiation such that the stabilizing composition does not stabilize the liquid resin but the formed article, and neutralizing free radicals generated during a degradation process initiated by exposure of the article to additional radiation post-cure.
    Type: Application
    Filed: January 15, 2018
    Publication date: March 25, 2021
    Inventors: Emily Ann RYAN, Mark Edward NICHOLS, Ellen Cheng-Chi LEE, Christopher Michael SEUBERT, Deborah Frances MIELEWSKI, Nicholas Ryan GUNTHER, Matthew Linden BEDELL
  • Patent number: 10953379
    Abstract: Methods and compositions are disclosed relating to the localization of nucleic acids to arrays such as silane-free arrays, and of sequencing the nucleic acids localized thereby.
    Type: Grant
    Filed: December 9, 2019
    Date of Patent: March 23, 2021
    Assignee: Illumina Cambridge Limited
    Inventors: Mark Edward Brennan Smith, Andrea Sabot, Isabelle Marie Julia Rasolonjatovo, Jean-Ernest Sohna Sohna, Adrian Martin Horgan, Harold Philip Swerdlow
  • Patent number: 10954863
    Abstract: A gas turbine engine includes a compressor, a turbine, and an engine shaft coupled to the compressor and the turbine; a gear assembly including a driveshaft and an accessory gearbox, the driveshaft rotatable by the engine shaft and the accessory gearbox rotatable by the driveshaft, the accessory gearbox including an AGB output, and the gear assembly defining a first overall gear ratio between the engine shaft and the AGB output; and a phasing gearbox coupled to the accessory gearbox and including a PGB output, and the phasing gearbox defining a second overall gear ratio between the AGB output of the accessory gearbox and the PGB output, wherein the second overall gear ratio is an inverse of the first overall gear ratio.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: March 23, 2021
    Assignee: GENERAL ELECTRIC COMPANY
    Inventor: Mark Edward Neubauer
  • Publication number: 20210081609
    Abstract: Techniques for reducing memory and processing resources used by a dialog system by sharing resources between pipelined processes of the dialog system. An integrated shared dictionary is constructed for concurrent use by automated speech recognition (ASR) and natural language understanding (NLU) subsystems of the dialog system. The integrated shared dictionary comprises multiple entries, with each entry comprising first information that is used by the ASR subsystem, second information used by the NLU subsystem, and information correlating the first information and the second information. The ASR subsystem uses the integrated shared dictionary to identify a dictionary entry containing a set of words corresponding to speech input. The dictionary entry information is communicated to the NLU subsystem, which uses the entry to generate a meaning representation for the speech input.
    Type: Application
    Filed: July 13, 2020
    Publication date: March 18, 2021
    Applicant: Oracle International Corporation
    Inventor: Mark Edward Johnson
  • Publication number: 20210082424
    Abstract: The present disclosure relates generally to determining intent based upon speech input using a dialog system. More particularly, techniques are described using matching-based machine learning techniques to identify an intent corresponding to speech input in a dialog system. These procedures do not require training when intents are added or removed from the set of possible intents.
    Type: Application
    Filed: July 29, 2020
    Publication date: March 18, 2021
    Applicant: Oracle International Corporation
    Inventor: Mark Edward Johnson
  • Publication number: 20210084477
    Abstract: A system for providing help includes a digital assistant and a network for connecting the digital assistants to a server. A plurality of agent computers is connected to the server. The digital assistant is preprogrammed and centrally managed with at least one skill for recognizing a preprogrammed specific utterance followed by a request for help. After the preprogrammed specific utterance and request for help is detected by the digital assistant, the digital assistant initiates a request for help to the server and upon receiving the request for the help, the server assigns one of the agent computers and presents medical information regarding the user at the agent computer for better determining the type of help needed.
    Type: Application
    Filed: November 16, 2020
    Publication date: March 18, 2021
    Applicant: Ways Investments, LLC
    Inventor: Mark Edward Gray
  • Publication number: 20210082414
    Abstract: Techniques are described for using data stored for a user in association with context levels to improve the efficiency and accuracy of dialog processing tasks. A dialog system stores historical dialog data in association with a plurality of configured context levels. The dialog system receives an utterance and identifies a term for disambiguation from the utterance. Based on a determined context level, the dialog system identifies relevant historical data stored to a database. The historical data may be used to perform tasks such as resolving an ambiguity based on user preferences, disambiguating named entities based on a prior dialog, and identifying previously generated answers to queries. Based on the context level, the dialog system can efficiently identify the relevant information and use the identified information to provide a response.
    Type: Application
    Filed: August 26, 2020
    Publication date: March 18, 2021
    Applicant: Oracle International Corporation
    Inventor: Mark Edward Johnson
  • Publication number: 20210081799
    Abstract: A model for a natural language understanding task is generated based on labeled data generated by a labeling model. The model for the natural language understanding task is smaller than the labeling model (i.e., with lower computational and memory requirements than the combined model), but with substantially the same performance as the labeling model. In some cases, the labeling model may be generated based on a large pre-trained model.
    Type: Application
    Filed: July 24, 2020
    Publication date: March 18, 2021
    Applicant: Oracle International Corporation
    Inventor: Mark Edward Johnson
  • Publication number: 20210082425
    Abstract: Techniques are described for training and executing a machine learning model using data derived from a database. A dialog system uses data from the database to generate related training data for natural language understanding applications. The generated training data is then used to train a machine learning model. This enables the dialog system to leverage a large amount of available data to speed up the training process as compared to conventional labeling techniques. The dialog system uses the trained machine learning model to identify a named entity from a received spoken utterance and generate and output a speech response based upon the identified named entity.
    Type: Application
    Filed: August 3, 2020
    Publication date: March 18, 2021
    Applicant: Oracle International Corporation
    Inventors: Mark Edward Johnson, Michael Rye Kennewick
  • Publication number: 20210082400
    Abstract: Techniques for stop word data augmentation for training chatbot systems in natural language processing. In one particular aspect, a computer-implemented method includes receiving a training set of utterances for training an intent classifier to identify one or more intents for one or more utterances; augmenting the training set of utterances with stop words to generate an augmented training set of out-of-domain utterances for an unresolved intent category corresponding to an unresolved intent; and training the intent classifier using the training set of utterances and the augmented training set of out-of-domain utterances. The augmenting includes: selecting one or more utterances from the training set of utterances, and for each selected utterance, preserving existing stop words within the utterance and replacing at least one non-stop word within the utterance with a stop word or stop word phrase selected from a list of stop words to generate an out-of-domain utterance.
    Type: Application
    Filed: September 9, 2020
    Publication date: March 18, 2021
    Applicant: Oracle International Corporation
    Inventors: Vishal Vishnoi, Mark Edward Johnson, Elias Luqman Jalaluddin, Balakota Srinivas Vinnakota, Thanh Long Duong, Gautam Singaraju
  • Publication number: 20210077991
    Abstract: A probe assembly for aspirating and delivering liquids includes a liquid line having a liquid line end and a pipette configured to be in fluid communication with the liquid line, the pipette configured to aspirate and dispense liquids when the probe assembly is devoid of connections to external liquid sources other than liquids being aspirated or dispensed, the liquid line end having a first portion of a dynamic coupler configured to be dynamically coupled to a second portion of a dynamic coupler, and the second portion of the dynamic coupler configured to be in fluid communication with a liquid source external to the probe assembly. Other probe assemblies, testing apparatus, and methods are disclosed.
    Type: Application
    Filed: December 5, 2018
    Publication date: March 18, 2021
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventor: Mark Edwards
  • Patent number: 10946086
    Abstract: The invention relates to immunogenic polysaccharide-protein conjugates comprising a capsular polysaccharide (CP) from Streptococcus agalactiae, commonly referred to as group B streptococcus (GBS), and a carrier protein, wherein the CP is selected from the group consisting of serotypes Ia, Ib, II, III, IV, V, VI, VII, VIII, and IX, and wherein the CP has a sialic acid level of greater than about 60%. The invention also relates to methods of making the conjugates and immunogenic compositions comprising the conjugates. The invention also relates to immunogenic compositions comprising polysaccharide-protein conjugates, wherein the conjugates comprise a CP from GBS serotype IV and at least one additional serotype. The invention further relates to methods for inducing an immune response in subjects against GBS and/or for reducing or preventing invasive GBS disease in subjects using the compositions disclosed herein. The resulting antibodies can be used to treat or prevent GBS infection via passive immunotherapy.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: March 16, 2021
    Assignee: Pfizer Inc.
    Inventors: Annaliesa Sybil Anderson, Amardeep Singh Bhupender Bhalla, Robert G. K. Donald, Jianxin Gu, Kathrin Ute Jansen, Rajesh Kumar Kainthan, Lakshmi Khandke, Jin-Hwan Kim, Paul Liberator, Avvari Krishna Prasad, Mark Edward Ruppen, Ingrid Lea Scully, Suddham Singh, Cindy Xudong Yang
  • Patent number: 10952052
    Abstract: A method for updating communication parameters on a mobile device, the method including sending a communication from the mobile device to a server, the communication including a location of the mobile device; receiving at the mobile device, responsive to the communication, a new communication parameter; reconfiguring the mobile device with the new communication parameter; and sending a second communication from the mobile device to the server, the second communication using the new communication parameter.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: March 16, 2021
    Assignee: BlackBerry Limited
    Inventors: Jason Wayne Jantzi, Scott Leonard Dill, Jesse William Bennett, Mark Edward Reaume, Mahendra Fuleshwar Prasad, Alexander Karl Levato, Yu Gao
  • Patent number: 10947512
    Abstract: Embodiments disclosed herein provide compositions, methods, and uses for respiratory syncytial viruses (RSV) and immunogenic compositions thereof. Certain embodiments provide RSV having a mutated NS1 protein, where the mutation causes the uncoupling of the NS1 protein's replication and type I interferon (IFN) antagonist functions. In some embodiments, this uncoupling can produce virions capable of inducing a strong, long-lasting innate immune response while maintaining its ability to replicate in vitro. Also provided are methods for amplifying RSV in host cells, wherein amplified RSV has mutated NS1 protein in which the protein's replication and IFN antagonistic functions are uncoupled. In certain embodiments, the amplified RSV having mutated NS1 protein is formulated into immunogenic compositions, including vaccines. Other embodiments provide methods for inducing an effective immune response against RSV infection in a subject.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: March 16, 2021
    Assignees: Research Institute at Nationwide Children's Hospital, The University of South Florida
    Inventors: Mark Edward Peeples, Michael Nan-hao Teng, Octavio Ramilo, Maria Asuncion Mejias, Emilio Flano
  • Publication number: 20210076206
    Abstract: A system and method for providing anonymous communications from a user to a called party includes obtaining a dedicated phone number and creating a user account for the user and assigning the dedicated phone number to the user account. A provider account is created for a digital assistant using the dedicated phone number and the digital assistant is preprogrammed with the user account. The digital assistant is also preprogrammed with a skill for recognizing a specific utterance (e.g. “Call”). Connectivity is provided between the digital assistant and the Internet, for example, using a wireless access point. The digital assistant listens for the specific utterance and, upon recognizing the specific utterance followed by an identification of the called party, the digital assistant initiates a voice call through the Internet to the called party.
    Type: Application
    Filed: November 6, 2020
    Publication date: March 11, 2021
    Applicant: Ways Investments, LLC
    Inventor: Mark Edward Gray
  • Publication number: 20210074274
    Abstract: Disclosed herein are techniques for using a generative adversarial network (GAN) to train a semantic parser of a dialog system. A method described herein involves accessing seed data that includes seed tuples. Each seed tuple includes a respective seed utterance and a respective seed logical form corresponding to the respective seed utterance. The method further includes training a semantic parser and a discriminator in a GAN. The semantic parser learns to map utterances to logical forms based on output from the discriminator, and the discriminator learns to recognize authentic logical forms based on output from the semantic parser. The semantic parser may then be integrated into a dialog system.
    Type: Application
    Filed: August 13, 2020
    Publication date: March 11, 2021
    Applicant: Oracle International Corporation
    Inventors: Thanh Long Duong, Mark Edward Johnson
  • Publication number: 20210073465
    Abstract: Techniques for improving a semantic parser of a dialog system, by breaking the semantic parser into a coarse semantic parser and a fine semantic parser, are described. A method described herein includes accessing an utterance received in a dialog system. The utterance is a text-based natural language expression. The method further includes applying a coarse semantic parser to the utterance to determine an intermediate logical form for the utterance. The intermediate logical form indicates one or more intents in the utterance. The method further includes applying a fine semantic parser to the intermediate logical form to determine a logical form for the utterance. The logical form is a syntactic expression of the utterance according to an established grammar, and the logical form includes one or more parameters of the one or more intents. The logical form can be used to conduct a dialog with a user of the dialog system.
    Type: Application
    Filed: August 13, 2020
    Publication date: March 11, 2021
    Applicant: Oracle International Corporation
    Inventors: Thanh Long Duong, Mark Edward Johnson
  • Publication number: 20210074262
    Abstract: Some techniques described herein determine a correction model for a dialog system, such that the correction model corrects output from an automatic speech recognition (ASR) subsystem in the dialog system. A method described herein includes accessing training data. A first tuple of the training data includes an utterance, where the utterance is a textual representation of speech. The method further includes using an ASR subsystem of a dialog system to convert the utterance to an output utterance. The method further includes storing the output utterance in corrective training data that is based on the training data. The method further includes training a correction model based on the corrective training data, such that the correction model is configured to correct output from the ASR subsystem during operation of the dialog system.
    Type: Application
    Filed: August 13, 2020
    Publication date: March 11, 2021
    Applicant: Oracle International Corporation
    Inventors: Thanh Long Duong, Mark Edward Johnson