Patents by Inventor Mark Rogers

Mark Rogers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrazol derivatives
    Patent number: 9694012
    Abstract: The invention relates to a compound of formula (I) wherein A1 to A3 and R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: July 4, 2017
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Uwe Grether, Atsushi Kimbara, Matthias Nettekoven, Fabienne Ricklin, Stephan Roever, Mark Rogers-Evans, Tanja Schulz-Gasch
  • PERSISTENT AUTONOMOUS AGENTS
    Publication number: 20170182418
    Abstract: The systems and methods are directed towards object driven attributes for characters within a network-based game. More specifically, characters within a network-based game have various attributes that are influenced with the association and/or possession of objects provided by the user. These user-provided objects impact one or more attributes possessed by a character within the network-based game thereby influencing the character's actions, personality and motivations. In other embodiments, the characters within the network-based game communicate with players using a variety of methods such as social media, e-mail and text. The communications provide in-game updates for the player to view. The player can provide natural language commands or responses for the characters that may influence the character's actions within the game.
    Type: Application
    Filed: October 31, 2016
    Publication date: June 29, 2017
    Inventor: Mark Rogers
  • Ventilation harm index
    Patent number: 9687618
    Abstract: A method for generating a ventilation harm index. The method includes accessing data from a plurality of ventilators in operation, analyzing an aggregate of the data, and generating the ventilation harm index based on the analyzed aggregated data.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: June 27, 2017
    Assignee: CAREFUSION 207, INC.
    Inventors: Tom Steinhauer, Timothy Riddle, Thomas George, Mark Rogers, Glen Gee
  • RADIOLABELED CANNABINOID RECEPTOR 2 LIGAND
    Publication number: 20170166534
    Abstract: The present invention relates to a compound of formula (I) wherein R1 is defined as in the description and in the claims. The compound of formula (I) can be used as radiolabeled ligand.
    Type: Application
    Filed: February 27, 2017
    Publication date: June 15, 2017
    Applicants: Hoffmann-La Roche Inc., EIDGENÖSSISCHE TECHNISCHE HOCHSCHULE ZÜRICH, UNIVERSITÄT ZÜRICH
    Inventors: Simon M. Ametamey, Juergen Fingerle, Luca Gobbi, Uwe Grether, Ahmed Haider, Thomas Hartung, Linjing Mu, Leo Nicholls, Mark Rogers-Evans, Christoph Ullmer
  • 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS
    Publication number: 20170157137
    Abstract: The present invention relates to a compound of formula (I) or a stereoisomer, enantiomer, racemic, or tautomer thereof, Formula (I), wherein R1, R3, R4, L1, L2, L3, L4, and n, have the same meaning as that defined in the claims and the description. The present invention also relates to compositions, in particular pharmaceuticals, comprising such compounds, and to uses of such compounds and compositions for the prevention and/or treatment of metabolic disorders and/or neurodegenerative diseases, and/or protein misfolding disorders.
    Type: Application
    Filed: February 15, 2017
    Publication date: June 8, 2017
    Applicant: REMYND NV
    Inventors: Gerard Griffioen, Bart De Taeye, Katrien Princen, Koen De Witte, Emilie Blanche, Hasane Ratni, Mark Rogers-Evans
  • APPARATUSES AND METHODS FOR SECURING DEEP BRAIN STIMULATION LEADS
    Publication number: 20170157388
    Abstract: Various examples are provided for securing deep brain stimulation (DBS) leads. In one example, among others, a DBS cap for securing a DBS lead includes a base ring adapted to be mounted within a counterbore opening formed in the skull, a lead securing element that mounts to the base ring, and. a top cover that mounts to the base ring. In another example, a method for securing a DBS lead includes forming a counterbore opening in the skull, securing a DBS cap within the counterbore opening, passing a DBS lead through the DBS cap and the counterbore opening and positioning a tip of the lead in brain tissue, and securing the DBS lead to the DBS cap using an adhesive. The skull opening includes a lower bore, a concentric upper bore, and a step positioned at the interface of the upper and lower bores.
    Type: Application
    Filed: February 21, 2017
    Publication date: June 8, 2017
    Inventors: Michael Scott Okun, Kelly D. Foote, Mark Roger Davidson
  • VENTILATION MANAGEMENT SYSTEM
    Publication number: 20170109491
    Abstract: Ventilator management systems are provided. In one aspect, a ventilator management system includes a memory that includes an initial configuration profile configured to designate operating parameters for a ventilation device, and a processor. The processor is configured to receive ventilator data from the ventilation device, the ventilator data includes at least one of operating parameters of the ventilation device or physiological statistics of a patient associated with the ventilation device, and determine, based on the ventilator data, a modification to the initial configuration profile for the ventilation device. The processor is also configured to generate a modified configuration profile for the ventilation device based on the determined modification. Methods and machine-readable media are also provided.
    Type: Application
    Filed: December 29, 2016
    Publication date: April 20, 2017
    Inventors: Tom STEINHAUER, Willis LAM, Mark ROGERS, Terry BLANSFIELD, Stephen J. BIRCH
  • 2,7-diazaspiro[3.5]nonane compounds
    Patent number: 9617264
    Abstract: The present invention relates to a compound of formula (I) or a stereoisomer, enantiomer, racemic, or tautomer thereof, Formula (I), wherein R1, R3, R4, L1, L2, L3, L4, and n, have the same meaning as that defined in the claims and the description. The present invention also relates to compositions, in particular pharmaceuticals, comprising such compounds, and to uses of such compounds and compositions for the prevention and/or treatment of metabolic disorders and/or neurodegenerative diseases, and/or protein misfolding disorders.
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: April 11, 2017
    Assignee: REMYND NV
    Inventors: Gerard Griffioen, Bart De Taeye, Katrien Princen, Koen De Witte, Emilie Blanche, Hasane Ratni, Mark Rogers-Evans
  • Layered audio reconstruction system
    Patent number: 9613660
    Abstract: A computing device may receive or otherwise access a base audio layer and one or more enhancement audio layers. The computing device can reconstruct the retrieved base layer and/or enhancement layers into a single data stream or audio file. The local computing device may process audio frames in a highest enhancement layer retrieved in which the data can be validated (or a lower layer if the data in audio frames in the enhancement layer(s) cannot be validated) and build a stream or audio file based on the audio frames in that layer.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: April 4, 2017
    Assignee: DTS, Inc.
    Inventors: Mark Rogers Johnson, Phillip L. Maness
  • Apparatuses and methods for securing deep brain stimulation leads
    Patent number: 9610437
    Abstract: Various examples are provided for securing deep brain stimulation (DBS) leads. In one example, among others, a DBS cap for securing a DBS lead includes a base ring adapted to be mounted within a counterbore opening formed in the skull, a lead securing element that mounts to the base ring, and, a top cover that mounts to the base ring. In another example, a method for securing a DBS lead includes forming a counterbore opening in the skull, securing a DBS cap within the counterbore opening, passing a DBS lead through the DBS cap and the counterbore opening and positioning a tip of the lead in brain tissue, and securing the DBS lead to the DBS cap using an adhesive. The skull opening includes a lower bore, a concentric upper bore, and a step positioned at the interface of the upper and lower bores.
    Type: Grant
    Filed: July 31, 2014
    Date of Patent: April 4, 2017
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Michael Scott Okun, Kelly D. Foote, Mark Roger Davidson
  • OXADIAZOLE COMPOUNDS
    Publication number: 20170073319
    Abstract: The present invention relates to a compound of formula (I) or (II) or a stereoisomer, enantiomer, racemic, or tautomer thereof, (I) (II) wherein R1, R2, R3, L1, L2, L3, L4, L5 and n, have the same meaning as that defined in the claims and the description. The present invention also relates to compositions, in particular pharmaceuticals, comprising such compounds, and to uses of such compounds and compositions for the prevention and/or treatment of metabolic disorders and/or neurodegenerative diseases, and/or protein misfolding disorders.
    Type: Application
    Filed: March 17, 2015
    Publication date: March 16, 2017
    Applicant: REMYND NV
    Inventors: Gerard GRIFFIOEN, Bart DE TAEYE, Katrien PRINCEN, Koen DE WITTE, Emilie BLANCHE, Hasane RATNI, Matthias NETTEKOVEN, Mark ROGERS-EVANS
  • Triazolo[4,5-D]pyrimidine derivatives
    Patent number: 9593123
    Abstract: The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: February 23, 2016
    Date of Patent: March 14, 2017
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Uwe Grether, Matthias Nettekoven, Mark Rogers-Evans, Stephan Roever, Sebastien Schmitt, Atsushi Kimbara
  • Pyrrolo[2,3-D]pyrimidine derivatives as CB2 receptor agonists
    Patent number: 9580435
    Abstract: The invention relates to a compound of formula (I) wherein A and R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: October 26, 2015
    Date of Patent: February 28, 2017
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Uwe Grether, Atsushi Kimbara, Matthias Nettekoven, Stephan Roever, Mark Rogers-Evans, Tanja Schulz-Gasch
  • NOVEL PYRAZOL DERIVATIVES
    Publication number: 20170035769
    Abstract: The invention relates to a compound of formula (I) wherein A1 to A3 and R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: October 24, 2016
    Publication date: February 9, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: UWE GRETHER, ATSUSHI KIMBARA, MATTHIAS NETTEKOVEN, FABIENNE RICKLIN, STEPHAN ROEVER, MARK ROGERS-EVANS, TANJA SCHULZ-GASCH
  • Layered audio coding and transmission
    Patent number: 9558785
    Abstract: Embodiments of systems and methods are described for generating layered audio such that computing devices can request a variable amount of data based on criteria such as their available bandwidth, device capability, or user selection. A base layer and one or more enhancement layers that incrementally enhance the previous layers may be generated. A computing device may retrieve the base layer and/or one or more enhancement layers, adjusting, in real-time or near real-time, which layers are retrieved based on fluctuations in the available bandwidth among other possible criteria.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: January 31, 2017
    Assignee: DTS, Inc.
    Inventors: Mark Rogers Johnson, Phillip L. Maness
  • 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS
    Publication number: 20170015665
    Abstract: The present invention relates to a compound of formula (I) or a stereoisomer, enantiomer, racemic, or tautomer thereof, Formula (I), wherein R1, R3, R4, L1, L2, L3, L4, and n, have the same meaning as that defined in the claims and the description. The present invention also relates to compositions, in particular pharmaceuticals, comprising such compounds, and to uses of such compounds and compositions for the prevention and/or treatment of metabolic disorders and/or neurodegenerative diseases, and/or protein misfolding disorders.
    Type: Application
    Filed: March 17, 2015
    Publication date: January 19, 2017
    Applicant: REMYND NV
    Inventors: Gerard Griffioen, Bart De Taeye, Katrien Princen, Koen De Witte, Emilie Blanche, Hasane Ratni, Mark Rogers-Evans
  • BACE1 inhibitors
    Patent number: 9540397
    Abstract: The present invention provides a compound of formula I, having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
    Type: Grant
    Filed: October 7, 2015
    Date of Patent: January 10, 2017
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Bjoern Bartels, Philipp Cueni, Cosimo Dolente, Wolfgang Guba, Wolfgang Haap, Andreas Kuglstatter, Ulrike Obst Sander, Jens-Uwe Peters, Mark Rogers-Evans, Walter Vifian, Thomas Woltering
  • NOVEL PYRIDINE DERIVATIVES
    Publication number: 20160376262
    Abstract: The invention relates to a compound of formula (I) wherein A and R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: September 9, 2016
    Publication date: December 29, 2016
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Luca Gobbi, Uwe Grether, Matthias Nettekoven, Stephan Roever, Mark Rogers-Evans
  • NOVEL PYRIDINE DERIVATIVES
    Publication number: 20160376237
    Abstract: The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: September 9, 2016
    Publication date: December 29, 2016
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Luca Gobbi, Uwe Grether, Matthias Nettekoven, Stephan Roever, Mark Rogers-Evans, Roger Slavik
  • Pyridine derivatives
    Patent number: 9522886
    Abstract: The invention relates to a compound of formula (I) wherein R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: December 2, 2013
    Date of Patent: December 20, 2016
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Beat Frei, Luca Gobbi, Uwe Grether, Atsushi Kimbara, Matthias Nettekoven, Stephan Roever, Mark Rogers-Evans, Tanja Schulz-Gasch