Abstract: Presented herein are techniques that use acoustic scene (environmental) analysis to determine the sound class of sound signals received at a hearing prosthesis and, accordingly, assess the estimated listening difficulty that the acoustic environment presents to a recipient of the hearing prosthesis. This difficulty of the recipient's listening situation can be used to adjust, adapt, or otherwise set the resolution of the electrical stimulation signals delivered to the recipient to evoke perception of the sound signals. In other words, the resolution of the electrical stimulation signals is dynamically adapted based on the present acoustic environment of the hearing prosthesis.

Abstract: The present disclosure relates to compositions and methods for treating autism spectrum disorder (ASD). Provided herein are pharmaceutical compositions and formulations comprising a preparation of uncultured fecal bacteria derived from a stool of a human donor and at least one, at least two, or all three of non-pathogenic microbial types selected from the group consisting of a bacterial isolate, a fungal isolate, and an archaeal isolate (e.g., a bacterial isolate comprising Lactobacillus reuteri), and methods of treating an ASD patient with the composition. Further provided are methods of manufacturing a pharmaceutical composition comprising L. reuteri.

Abstract: An apparatus includes a cannula with at least one wall portion having an electrically insulating material. The at least one wall portion at least partially bounds a region configured to contain a portion of a medical implant system configured to be implanted on or within a recipient. The cannula further includes at least one portion configured to provide at least one electrically conductive pathway through the at least one wall portion from within the cannula to a region outside the cannula.

Abstract: A configurable build volume system for a powder bed fusion manufacturing process includes a chamber wall defining a chamber, the chamber wall extending in the X-, Y-, and Z-axis directions, a plurality of build platforms enclosed within the chamber, a plurality of adjustment mechanisms coupled to the plurality of build platforms such that each build platform is coupled to a separate adjustment mechanism, a sensor mounted within the chamber and configured to capture data regarding a Z-axis position of each of the plurality of build platforms, and a controller in electronic communication with the plurality of adjustment mechanisms and the sensor. The controller receives the Z-axis position data and generates a plurality of control signals to adjust a Z-axis position of each of the plurality of build platforms and each of the plurality of build platforms is actively and independently controlled by the controller.

Abstract: Compounds, compositions and methods are provided for the inhibition of ENPP1. Aspects of the subject methods include contacting a sample with an ENPP1 inhibitor compound to inhibit the cGAMP hydrolysis activity of ENPP1. In some cases, the ENPP1 inhibitor compound is cell impermeable. ENPP1 inhibitor compounds can act extracellularly to block the degradation of cGAMP. Also provided are pharmaceutical compositions and methods for treating cancer. Aspects of the methods include administering to a subject a therapeutically effective amount of an ENPP1 inhibitor to treat the subject for cancer. In certain cases, the cancer is a solid tumor cancer. Also provided are methods of administering radiation therapy to a subject in conjunction with administering an ENPP1 inhibitor to the subject. The radiation therapy can be administered in the subject methods at a dosage and/or frequency effective to reduce radiation damage to the subject, but still instigate an immune response.

Abstract: A vehicle body for a multi-platform, reconfigurable electric truck includes a front trunk, an extendable bed and barn door tailgates, a sidewall table, and a side step and drawer. The front trunk includes a cover movable between a closed and open positions, and includes panels selectively movable between a retracted and extended positions to form a work surface. A bed extender slides between a retracted and extended positions. Barn door tailgates each move between closed, partially open, and fully open positions and include inner tailgates movable between stowed and deployed positions. The barn door tailgates and the inner tailgates enclose an extended region of a bed when the bed extender is extended position, the barn door tailgates are each partially open, and the inner tailgates are each deployed. The sidewall table folds down from a sidewall, and the drawer pulls out from a sidewall.

Abstract: An axle assembly having a drop gear set and a countershaft transmission. The drop gear set may operatively connect a rotor of an electric motor to a countershaft. The countershaft transmission may operatively connect the countershaft to a drive pinion. The electric motor and the countershaft transmission may be positioned on opposite sides of a differential assembly.

Abstract: Methods and systems for a storage environment are provided. One method includes splitting storage of a plurality of zoned solid-state drives (ZNS SSDs) into a plurality of physical zones (PZones) across a plurality of independent media units of each ZNS SSD, the PZones visible to a first tier RAID (redundant array of independent disks) layer; generating a plurality of RAID zones (RZones), each RZone having a plurality of PZones; presenting one or more RZones to a second tier RAID layer by the first tier RAID layer for processing read and write requests using the plurality of ZNS SSDs; and utilizing, by the first tier RAID layer, a parity PZone at each ZNS SSD for storing parity information corresponding to data written in one or more PZone corresponding to a RZone presented to the second tier RAID layer and storing the parity information in a single parity ZNS SSD.

Abstract: A system for automated horseshoeing. The system is a three cell concept generally including a tool change area, a gluing area and a modification area. The system generally include a platform for a horse to stand thereon wherein all working components are contained below. The system is configured so that a horse can stand on said platform and the working components move from hoof to hoof thereby allowing the horse to remain in a neutral standing position during the entire shoeing process without having to bend it's ankle. The automated horseshoeing process of the present specification is entirely monitored by a farrier.

Abstract: The various embodiments described herein relate to systems, methods, and devices associated with distributed ledger systems (e.g., distributed ledger technology implemented on a decentralized network) that can be used to handle and manage the distribution and access of data in a manner that preserves the benefits of distributed ledger technology while enabling the private sharing of data. More specifically, the distributed ledger systems contemplated herein involve distributed ledger technology (DLT)-based data management platforms that can be implemented on nodes of a data management network.

Abstract: Extended-release microsphere formulations comprising lurasidone are provided. In one aspect, the microsphere formulations are characterized in that the lurasidone is released in vivo in humans over a period of about 30 days. Methods for making and using the formulations are also provided.

Abstract: Described herein are compositions and methods for the delivery of microbial therapeutics useful for the treatment of disorders related to intestinal dysbiosis.

Abstract: Described herein are compositions and methods for the delivery of microbial therapeutics useful for the treatment of disorders related to intestinal dysbiosis.

Abstract: An axle assembly having an electric motor module and a terminal box that may facilitate mounting of at least one phase cable. The phase cable may be secured to a terminal box cover with a terminal box clamp. The phase cable may extend through a phase block that may be mounted to the terminal box.

Abstract: Described are a method, system, and computer program product for deduplicating a storage object. A hash of a window of data of a storage object is determined and a determination is made as to whether the window of data of the storage object corresponds to a chunk boundary. A determination is made as to whether the hash of the object matches one pseudo fingerprints in a list of at least one pseudo fingerprint. A storage object chunk boundary based on the window of data is stored in response to the window of data corresponding to the chunk boundary or in response to determining that the hash of the object matches one of the pseudo fingerprints. A determination is made of a new window of data in the storage object following the window of data when the window of data is not an end of data of the storage object.

Abstract: A method for communicating information related to a diagnostic analyzer includes receiving user identification information from a portable computer. A user associated with the user identification information operates the diagnostic analyzer. First diagnostic analyzer information is retrieved from at least one database that relates analyzer information to the user of the diagnostic analyzer. The first diagnostic analyzer information is related to the diagnostic analyzer. The first diagnostic analyzer information is communicated to the portable computer. Second diagnostic analyzer information from the diagnostic analyzer is retrieved. The second diagnostic analyzer information is generated by the diagnostic analyzer. The first and the second diagnostic analyzer information is communicated to the portable computer. The portable computer is configured to display the first and the second diagnostic analyzer related information.

Abstract: A new garden type Chrysanthemum plant named ‘CIFZ0091’ particularly distinguished by its medium size plant with mound plant habit, small to medium sized decorative flowers with yellow flower color, and a natural season response early to mid-October.

Abstract: A new garden type Chrysanthemum plant named ‘CIFZ0092’ particularly distinguished by its medium size plant with mound plant habit, medium to large size daisy flowers, bicolor flower pattern with dark pink petal tips and cream yellow petal base and a natural season response early to mid-September.

Abstract: A new garden type Chrysanthemum plant named ‘CIFZ0094’ particularly distinguished by its medium size plant with mound plant habit, medium to small sized decorative flowers with white flower color, and a natural season response early to mid-October.

Abstract: A new garden type Chrysanthemum plant named ‘CIFZ0093’ particularly distinguished by its medium to large sized plant with round plant habit, medium to large sized daisy flowers with dark pink flower color, and a natural season response early to mid-September.