Patents by Inventor Markus Gerhard

Markus Gerhard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the manufacture of thrombin inhibitors
    Patent number: 5728549
    Abstract: The invention relates to DNA sequences that code for the amino acid sequence of the thrombin inhibitor hirudin, hybrid vectors containing such DNA sequences, host cells transformed with such hybrid vectors, novel polypeptides with thrombin-inhibiting activity produced from such transformed host cells, processes for the manufacture of these DNA sequences, hybrid vectors and transformed host cells, and processes for the manufacture of these thrombin-inhibitors using the transformed host cells. The hirudin compounds that can be produced according to the invention have valuable pharmacological properties.
    Type: Grant
    Filed: March 3, 1995
    Date of Patent: March 17, 1998
    Assignee: Novartis Corporation
    Inventors: Manfred Liersch, Hans Rink, Walter Marki, Markus Gerhard Grutter, Bernd Meyhack