Abstract: An automation device configured for an automation environment for automating an industrial process includes a housing and a printed circuit board that supports a microprocessor thermally connected with a heat sink that has a plurality of cooling fins each arranged parallel to the printed circuit board with a gap between each other such that, for a first installation position in which the lower side is aligned horizontally, a cooling medium flows from the lower side through the gaps, where the cooling fins have a first, second and third surfaces, and where the second surface is arranged between the first and third surfaces such inclined plane relative to the first and third surfaces is formed and such that, for a second installation position, in which the lower side is aligned vertically, the cooling medium flows over the inclined planes arranged one above the other.

Abstract: An automation device configured for use in an automation environment for automation of an industrial process includes an enclosure and a printed circuit board arranged parallel to first and second side parts at right angles to an upper or underside of the enclosure, wherein the printed circuit board carries a microprocessor in thermal connection with a heat sink that has cooling metal sheets, where the heat sink has a plurality of cooling metal sheets each arranged parallel to the printed circuit board with a clearance between them such that, for a first installation position in which the underside is aligned horizontally, a cooling medium flows from the underside through clearances, and where openings are each arranged in the cooling metal sheets such that, for a second installation position in which the underside is aligned vertically, the cooling medium flows through the openings arranged one above the other.

Abstract: Embodiments herein relate to optical chemical sensor systems that can be wearable and include microneedle arrays. In an embodiment, a chemical sensing device is included having a set of microneedles and a sensor element. The sensor element can include a first low-index gel layer, a second low-index gel layer, and a chromoionophore sensing film disposed between the first low-index gel layer and the second low-index gel layer. In an embodiment, a delay layer can be disposed between the sensor element and the set of microneedles. An optical emitter can be configured to emit light into the sensor element. An optical detector can be configured to receive light from the sensor element. Other embodiments are also included herein.

Abstract: Embodiments herein relate to optical chemical sensor systems that can be wearable and include microneedle arrays. In an embodiment, a chemical sensing device can be included having an optical transmission layer. The optical transmission layer can define a plurality of microneedles. The chemical sensing device can include a plurality of sensor elements and one or more optical emitters, wherein the one or more optical emitters can be configured to emit light into the plurality of sensor elements. The chemical sensing device can also include a plurality of optical detectors, wherein the plurality of optical detectors can be configured to receive light from the plurality of sensor elements. Other embodiments are also included herein.

Abstract: In an embodiment, a multifunctional material system is provided and can include a variable-permeability layer, a desiccant containing layer, and a vapor-permeable supporting layer. The variable-permeability layer can have a vapor permeability that increases with increasing relative humidity. The desiccant containing layer can be adjacent the variable-permeability layer. The vapor-permeable supporting layer can be positioned adjacent at least one of the variable-permeability layer and the desiccant containing layer. Water moves in a first direction from the variable-permeability layer to the desiccant layer when relative humidity is greater adjacent the variable-permeability layer than the desiccant layer. Water moves a second, opposing direction, from the desiccant containing layer to the variable-permeability layer when the relative humidity is greater adjacent the desiccant containing layer than the variable-permeability layer.

Abstract: A physical neural network system includes a physical and digital component. The digital component includes a computing system. The physical component and the digital component work in conjunction to execute a physics aware training process. The physics aware training process includes generating, by the digital component, an input data set for input to the physical component, applying, by the physical component, one or more transformations to the input data set to generate an output for a forward pass of the physics aware training process, comparing, by the digital component, the generated output to a canonical output to determine an error, generating, by the digital component, a loss gradient using a differentiable digital model for a backward pass of the physics aware training process, and updating, by the digital component, training parameters for subsequent input to the physical component based on the loss gradient.

Abstract: In an embodiment, a multifunctional material system is provided and can include a variable-permeability layer, a desiccant containing layer, and a vapor-permeable supporting layer. The variable-permeability layer can have a vapor permeability that increases with increasing relative humidity. The desiccant containing layer can be adjacent the variable-permeability layer. The vapor-permeable supporting layer can be positioned adjacent at least one of the variable-permeability layer and the desiccant containing layer. Water moves in a first direction from the variable-permeability layer to the desiccant layer when relative humidity is greater adjacent the variable-permeability layer than the desiccant layer. Water moves a second, opposing direction, from the desiccant containing layer to the variable-permeability layer when the relative humidity is greater adjacent the desiccant containing layer than the variable-permeability layer.

Abstract: A system passively cools, regulates humidity and/or rectifies diffusive transport of water vapor in an interior area within a structure. The system includes a membrane assembly covering a portion of the structure, wherein the membrane has an interior side facing the interior area and an exterior side. The membrane assembly defines a plurality of pores. When cooling, a supply of fluid is provided to the membrane assembly so that capillary action of the pores redistributes the fluid to create evaporation and, in turn, the desired heat flow. The membrane assembly can include an architectural membrane coated with a porous matrix coating to form the pores. A pump can provide the fluid to the interior side of the membrane assembly. Preferably, the architectural membrane is woven PTFE-coated fiberglass and the porous matrix coating is titanium dioxide, zeolites and/or silica gel.

Abstract: In an embodiment, a multifunctional material system is provided and can include a variable-permeability layer, a desiccant containing layer, and a vapor-permeable supporting layer. The variable-permeability layer can have a vapor permeability that increases with increasing relative humidity. The desiccant containing layer can be adjacent the variable-permeability layer. The vapor-permeable supporting layer can be positioned adjacent at least one of the variable-permeability layer and the desiccant containing layer. Water moves in a first direction from the variable-permeability layer to the desiccant layer when relative humidity is greater adjacent the variable-permeability layer than the desiccant layer. Water moves a second, opposing direction, from the desiccant containing layer to the variable-permeability layer when the relative humidity is greater adjacent the desiccant containing layer than the variable-permeability layer.

Abstract: In an embodiment, a multifunctional material system is provided and can include a variable-permeability layer, a desiccant containing layer, and a vapor-permeable supporting layer. The variable-permeability layer can have a vapor permeability that increases with increasing relative humidity. The desiccant containing layer can be adjacent the variable-permeability layer. The vapor-permeable supporting layer can be positioned adjacent at least one of the variable-permeability layer and the desiccant containing layer. Water moves in a first direction from the variable-permeability layer to the desiccant layer when relative humidity is greater adjacent the variable-permeability layer than the desiccant layer. Water moves a second, opposing direction, from the desiccant containing layer to the variable-permeability layer when the relative humidity is greater adjacent the desiccant containing layer than the variable-permeability layer.

Abstract: A system passively cools, regulates humidity and/or rectifies diffusive transport of water vapor in an interior area within a structure. The system includes a membrane assembly covering a portion of the structure, wherein the membrane has an interior side facing the interior area and an exterior side. The membrane assembly defines a plurality of pores. When cooling, a supply of fluid is provided to the membrane assembly so that capillary action of the pores redistributes the fluid to create evaporation and, in turn, the desired heat flow. The membrane assembly can include an architectural membrane coated with a porous matrix coating to form the pores. A pump can provide the fluid to the interior side of the membrane assembly. Preferably, the architectural membrane is woven PTFE-coated fiberglass and the porous matrix coating is titanium dioxide, zeolites and/or silica gel.

Abstract: A system passively cools, regulates humidity and/or rectifies diffusive transport of water vapor in an interior area within a structure. The system includes a membrane assembly covering a portion of the structure, wherein the membrane has an interior side facing the interior area and an exterior side. The membrane assembly defines a plurality of pores. When cooling, a supply of fluid is provided to the membrane assembly so that capillary action of the pores redistributes the fluid to create evaporation and, in turn, the desired heat flow. The membrane assembly can include an architectural membrane coated with a porous matrix coating to form the pores. A pump can provide the fluid to the interior side of the membrane assembly. Preferably, the architectural membrane is woven PTFE-coated fiberglass and the porous matrix coating is titanium dioxide, zeolites and/or silica gel.

Abstract: The present invention relates to a method for genomic and/or genetic analysis of a human nucleic acid sample, the method comprising the steps of providing a group of human reference genomes; testing of the human nucleic acid sample for sex and/or ancestry; selecting one or more population-specific human reference genomes, PHREGs, from the group of human reference genomes on the basis on the results of the sex and/or ancestry test; and aligning the human nucleic acid sample to the selected PHREGs; and variant calling against the selected PHREGs. The present invention also provides respective computer systems and computer programs.

Abstract: A system passively cools, regulates humidity and/or rectifies diffusive transport of water vapor in an interior area within a structure. The system includes a membrane assembly covering a portion of the structure, wherein the membrane has an interior side facing the interior area and an exterior side. The membrane assembly defines a plurality of pores. When cooling, a supply of fluid is provided to the membrane assembly so that capillary action of the pores redistributes the fluid to create evaporation and, in turn, the desired heat flow. The membrane assembly can include an architectural membrane coated with a porous matrix coating to form the pores. A pump can provide the fluid to the interior side of the membrane assembly. Preferably, the architectural membrane is woven PTFE-coated fiberglass and the porous matrix coating is titanium dioxide, zeolites and/or silica gel.

Abstract: A light module for a motor vehicle headlight for emitting light to form a light pattern in an area in front of the light module, the light module including two or more primary light sources (PLQ1, PLQ2) that produce light to form a main light pattern (HLV), and at least one secondary light source (SLQ1) that produces light to form an additional light pattern (ZLV), which overlaps the main light pattern to form an entire light pattern. The primary light sources are associated with at least one primary reflector (PR1, PR2) and are configured to bundle the light emitted the from the primary light sources and to direct it in the form of the main light pattern into an area in front of the light module.

Abstract: A system passively cools, regulates humidity and/or rectifies diffusive transport of water vapor in an interior area within a structure. The system includes a membrane assembly covering a portion of the structure, wherein the membrane has an interior side facing the interior area and an exterior side. The membrane assembly defines a plurality of pores. When cooling, a supply of fluid is provided to the membrane assembly so that capillary action of the pores redistributes the fluid to create evaporation and, in turn, the desired heat flow. The membrane assembly can include an architectural membrane coated with a porous matrix coating to form the pores. A pump can provide the fluid to the interior side of the membrane assembly. Preferably, the architectural membrane is woven PTFE-coated fiberglass and the porous matrix coating is titanium dioxide, zeolites and/or silica gel.

Abstract: Implantable medical device systems and methods of use including an implantable first medical device having a lead with a transducer thereon and an implantable second medical device having a receiver for receiving energy emitted by the transducer. The lead may be placed in an internal thoracic vein, and other locations may be used as well. The implantable second medical device may be placed in or on the heart or an associated blood vessel.

Abstract: The present disclosure relates to systems and methods for bioinformatics and data processing. In particular, in a first aspect, the present disclosure relates to methods and systems for generating a personalized treatment guideline for a patient and for selecting a treatment for a patient. In another aspect, the present disclosure relates to methods and systems for selecting patients for a clinical trial of a treatment. The invention resolves cases in which patients have more than one “actionable” aberration by combining the patient-specific molecular information and the treatment-specific molecular information further with a clinico-molecular disease model, specifically a scoring of genes and/or proteins that represents several aspects of their involvement into the disease. In this way, treatments and patients can be prioritized that are most likely to impact or impacted by the disease mechanism, respectively.

Abstract: In an embodiment, a multifunctional material system is provided and can include a variable-permeability layer, a desiccant containing layer, and a vapor-permeable supporting layer. The variable-permeability layer can have a vapor permeability that increases with increasing relative humidity. The desiccant containing layer can be adjacent the variable-permeability layer. The vapor-permeable supporting layer can be positioned adjacent at least one of the variable-permeability layer and the desiccant containing layer. Water moves in a first direction from the variable-permeability layer to the desiccant layer when relative humidity is greater adjacent the variable-permeability layer than the desiccant layer. Water moves a second, opposing direction, from the desiccant containing layer to the variable-permeability layer when the relative humidity is greater adjacent the desiccant containing layer than the variable-permeability layer.

Abstract: A light module for a motor vehicle headlight for emitting light to form a light pattern in an area in front of the light module, the light module including two or more primary light sources (PLQ1, PLQ2) that produce light to form a main light pattern (HLV), and at least one secondary light source (SLQ1) that produces light to form an additional light pattern (ZLV), which overlaps the main light pattern to form an entire light pattern. The primary light sources are associated with at least one primary reflector (PR1, PR2) and are configured to bundle the light emitted the from the primary light sources and to direct it in the form of the main light pattern into an area in front of the light module.