Abstract: A control unit for use in a laser system for working a workpiece by a laser beam is configured to capture, based on at least one translation axis position, a translational position of a working head which can be changed by a movement unit, capture, based on at least one rotation axis position, a rotational orientation of the working head which can be changed by the movement unit, and issue or revoke a laser beam release for an application of the laser beam to the workpiece. The laser beam release depends on a serial test of the translational position and the rotational orientation of the working head.

Abstract: Methods, devices, and systems for managing programmable photonic waveguides are provided. In one aspect, a method includes: varying respective localized electric fields across a plurality of regions of a waveguide core of a waveguide structure of a programmable photonic waveguide to cause corresponding local variations in at least one of a refractive index or a nonlinear susceptibility of the waveguide core, and programming an optical signal by coupling the optical signal through the waveguide core with the corresponding local variations in the at least one of the refractive index or the nonlinear susceptibility of the waveguide core.

Abstract: A physical neural network system includes a physical and digital component. The digital component includes a computing system. The physical component and the digital component work in conjunction to execute a physics aware training process. The physics aware training process includes generating, by the digital component, an input data set for input to the physical component, applying, by the physical component, one or more transformations to the input data set to generate an output for a forward pass of the physics aware training process, comparing, by the digital component, the generated output to a canonical output to determine an error, generating, by the digital component, a loss gradient using a differentiable digital model for a backward pass of the physics aware training process, and updating, by the digital component, training parameters for subsequent input to the physical component based on the loss gradient.

Abstract: The present invention relates to a method for genomic and/or genetic analysis of a human nucleic acid sample, the method comprising the steps of providing a group of human reference genomes; testing of the human nucleic acid sample for sex and/or ancestry; selecting one or more population-specific human reference genomes, PHREGs, from the group of human reference genomes on the basis on the results of the sex and/or ancestry test; and aligning the human nucleic acid sample to the selected PHREGs; and variant calling against the selected PHREGs. The present invention also provides respective computer systems and computer programs.

Abstract: A light module for a motor vehicle headlight for emitting light to form a light pattern in an area in front of the light module, the light module including two or more primary light sources (PLQ1, PLQ2) that produce light to form a main light pattern (HLV), and at least one secondary light source (SLQ1) that produces light to form an additional light pattern (ZLV), which overlaps the main light pattern to form an entire light pattern. The primary light sources are associated with at least one primary reflector (PR1, PR2) and are configured to bundle the light emitted the from the primary light sources and to direct it in the form of the main light pattern into an area in front of the light module.

Abstract: The present disclosure relates to systems and methods for bioinformatics and data processing. In particular, in a first aspect, the present disclosure relates to methods and systems for generating a personalized treatment guideline for a patient and for selecting a treatment for a patient. In another aspect, the present disclosure relates to methods and systems for selecting patients for a clinical trial of a treatment. The invention resolves cases in which patients have more than one “actionable” aberration by combining the patient-specific molecular information and the treatment-specific molecular information further with a clinico-molecular disease model, specifically a scoring of genes and/or proteins that represents several aspects of their involvement into the disease. In this way, treatments and patients can be prioritized that are most likely to impact or impacted by the disease mechanism, respectively.

Abstract: A light module for a motor vehicle headlight for emitting light to form a light pattern in an area in front of the light module, the light module including two or more primary light sources (PLQ1, PLQ2) that produce light to form a main light pattern (HLV), and at least one secondary light source (SLQ1) that produces light to form an additional light pattern (ZLV), which overlaps the main light pattern to form an entire light pattern. The primary light sources are associated with at least one primary reflector (PR1, PR2) and are configured to bundle the light emitted the from the primary light sources and to direct it in the form of the main light pattern into an area in front of the light module.

Abstract: A motor vehicle includes a vehicle body, a drive motor, and a water tank delimited by walls. At least one airbag module includes a gas generator and an airbag configured to deploy in the area of an exterior of the motor vehicle for the protection of pedestrians or the like. The airbag module is fastened above the wall of the water tank. A device for lifting a front hood from a closed initial position into an accident position, which is partially open in the area of the front windscreen.

Abstract: The invention relates to a light module for a motor vehicle headlight for emitting light to form a light pattern in an area in front of the light module, the light module comprising two or more primary light sources (PLQ1, PLQ2) that produce light to form a main light pattern (HLV), and at least one secondary light source (SLQ1) that produces light to form an additional light pattern (ZLV), the additional light pattern overlapping the main light pattern to form an entire light pattern, the primary light sources (PLQ1, PLQ2) being associated with at least one primary reflector (PR1, PR2) and being set up to bundle the light emitted the from the primary light sources (PLQ1, PLQ2) and to direct it in the form of the main light pattern (HLV) into an area in front of the light module, the at least one secondary light source (SLQ1) being associated with an optical imaging system (AS) and being set up to project the light emitted from the at least one secondary light source (SLQ1) in the form of the additional light

Abstract: A lighting module (1) for a vehicle headlamp (2), wherein the lighting module (1) comprises at least one lighting element (3), which is excitable to emit visible light when illuminated by laser light, and at least one light-transmissive carrier element (4), wherein the carrier element (4) has at least one light-entry face (4a) and at least one light-exit face (4b) lying opposite the light-entry face (4a), wherein the at least one lighting element (3) is arranged at the at least one light-entry face (4a) of the carrier element (4) in order to radiate light into the light-entry face (4a), wherein a) the at least one light-exit face (4b) of the carrier element (4) is delimited by a light-opaque mask (5) surrounding the light-exit face (4b) or b) the at least one light-exit face (4b) reaches up to the side faces (6a to 6d) of the carrier element (4), wherein at least one side face (6b) has two side portions (6b?, 6b?) adjoining one another, said side portions being inclined relative to one another for forming a l

Abstract: A device for mounting a headrest in a seat structure of a vehicle seat, in particular a vehicle seat of an automobile. The device includes a connecting part formed from a plate and a tubular receiving element for a retaining rod of a headrest. The receiving element is connected to a bearing section of the connecting part. The connecting part includes a supporting section configured at an angle to the bearing section. The supporting section contacts a seat structure of a vehicle seat in the vehicle height direction.

Abstract: The invention relates to a light module for a motor vehicle headlight for emitting light to form a light pattern in an area in front of the light module, the light module comprising two or more primary light sources (PLQ1, PLQ2) that produce light to form a main light pattern (HLV), and at least one secondary light source (SLQ1) that produces light to form an additional light pattern (ZLV), the additional light pattern overlapping the main light pattern to form an entire light pattern, the primary light sources (PLQ1, PLQ2) being associated with at least one primary reflector (PR1, PR2) and being set up to bundle the light emitted the from the primary light sources (PLQ1, PLQ2) and to direct it in the form of the main light pattern (HLV) into an area in front of the light module, the at least one secondary light source (SLQ1) being associated with an optical imaging system (AS) and being set up to project the light emitted from the at least one secondary light source (SLQ1) in the form of the additional light

Abstract: A lighting module (1) for a vehicle headlamp (2), wherein the lighting module (1) comprises at least one lighting element (3), which is excitable to emit visible light when illuminated by laser light, and at least one light-transmissive carrier element (4), wherein the carrier element (4) has at least one light-entry face (4a) and at least one light-exit face (4b) lying opposite the light-entry face (4a), wherein the at least one lighting element (3) is arranged at the at least one light-entry face (4a) of the carrier element (4) in order to radiate light into the light-entry face (4a), wherein a) the at least one light-exit face (4b) of the carrier element (4) is delimited by a light-opaque mask (5) surrounding the light-exit face (4b) or b) the at least one light-exit face (4b) reaches up to the side faces (6a to 6d) of the carrier element (4), wherein at least one side face (6b) has two side portions (6b?, 6b?) adjoining one another, said side portions being inclined relative to one another for forming a l

Abstract: A vibration module for integration into a vehicle seat includes a plurality of vibration elements, a first flat covering layer and a second flat covering layer. The vibration elements are arranged between the first covering layer and the second covering layer. The positions of the vibration elements are fixed relative to the first covering layer and/or second covering layer.

Abstract: There is disclosed a molecular composition(s) of a novel tissue protective erythropoietin (EPO) binding receptor protein complex, termed NEPOR. Presence of NEPOR components on a tumour allows EPO to impinge on the survival of associated cells thereby enhancing tumour progression and negatively effecting patient survival. Presence of NEPOR represents a prognostic biomarker for poorer patient outcome. Thus, methods are provided for stratifying patients having a tumour as suitable (i.e. NEPOR not present) or non-suitable (i.e., NEPOR present) for EPO treatment, comprising: (a) isolating a tissue sample from an individual who is receiving or is a candidate for receiving erythropoietin, (b) determining the level of expression of the NEPOR gene(s) (mRNA) and/or the presence of the NEPOR gene product (protein) from the isolated tissue, and (c) correlating the presence of an NEPOR gene expression product or the presence of NEPOR protein to a physiological response to the treatment with erythropoietin.

Abstract: A motor vehicle includes a vehicle body, a drive motor, and a water tank delimited by walls. At least one airbag module includes a gas generator and an airbag configured to deploy in the area of an exterior of the motor vehicle for the protection of pedestrians or the like. The airbag module is fastened above the wall of the water tank. A device for lifting a front hood from a closed initial position into an accident position, which is partially open in the area of the front windscreen.

Abstract: A device for mounting a headrest in a seat structure of a vehicle seat, in particular a vehicle seat of an automobile. The device includes a connecting part formed from a plate and a tubular receiving element for a retaining rod of a headrest. The receiving element is connected to a bearing section of the connecting part. The connecting part includes a supporting section configured at an angle to the bearing section. The supporting section contacts a seat structure of a vehicle seat in the vehicle height direction.

Abstract: A backrest for a back seat of a motor vehicle is pivotable between a usage and folded position. A lateral part is arranged next to the backrest in usage position and forms a gap therebetween. A safety belt adjacent to the gap rests on a contact surface of the lateral part. A guide element is arranged in the gap and mounted in the lateral part for moving from an operative position partially projecting out of the gap and too a non-operative position completely retracted in the gap and vice versa. The guide element projects over the contact surface in the operative position. The guide element is moved from the operative position into the non-operative position against a spring force when the backrest pivots into the usage position.

Abstract: The invention relates to a vehicle headlamp (1) for producing a main light distribution and an auxiliary light distribution, wherein the vehicle headlamp (1) comprises two or more LED light modules (10), wherein each of the LED light modules (10) comprises one or more primary LED light sources (11), wherein a primary LED light source (11?) comprises at least one light-emitting diode, comprises two or more secondary LED light sources (12, 12a), wherein a secondary LED light source (12, 12a) comprises at least one light-emitting diode (12?), and comprises a lens (13), wherein the light emitted by the at least one primary LED light source (11) is radiated directly onto the lens (13) and projected by the lens into the exterior space, wherein the light emitted by the primary LED light sources (11) of a all LED modules (10) forms the main light distribution, and wherein the light emitted by the secondary LED light sources (12, 12a) of an LED modules (10) is radiated onto the lens (13) of the LED module (10) by mean

Abstract: The present disclosure relates to systems and methods for bioinformatics and data processing. In particular, in a first aspect, the present disclosure relates to methods and systems for generating a personalized treatment guideline for a patient and for selecting a treatment for a patient. In another aspect, the present disclosure relates to methods and systems for selecting patients for a clinical trial of a treatment. The invention resolves cases in which patients have more than one “actionable” aberration by combining the patient-specific molecular information and the treatment-specific molecular information further with a clinico-molecular disease model, specifically a scoring of genes and/or proteins that represents several aspects of their involvement into the disease. In this way, treatments and patients can be prioritized that are most likely to impact or impacted by the disease mechanism, respectively.