Patents by Inventor Masahiro Ishizuka
Masahiro Ishizuka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8563605Abstract: The present invention is intended to provide an agent for treating male infertility which is highly effective to male infertility, and having few side effects. To achieve the object, an agent for treating male infertility comprising ?-amino levulinic acid shown by general formula (1), its derivative or salt thereof: R2R1NCH2COCH2CH2COR3??(1) [wherein R1 and R2 independently represent a hydrogen atom, alkyl group, acyl group, alkoxycarbonyl group, aryl group, or aralkyl group; R3 represents a hydroxy group, alkoxy group, acyloxy group, alkoxycarbonyloxy group, aryloxy group, aralkyloxy group or amino group] can be used.Type: GrantFiled: May 13, 2009Date of Patent: October 22, 2013Assignee: SBI Pharmaceuticals Co., Ltd.Inventors: Setsuko Miyanari, Masumi Takahashi, Masahiro Ishizuka, Tohru Tanaka
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Patent number: 8523391Abstract: A flat light source apparatus has a light source board which comprises unit boards, each unit board having a printed circuit board and a light source formed on the printed circuit board, wherein the unit boards are arranged adjacent to each other at least in one direction, and any pair of the unit boards adjacent to each other is integrated by a connecting portion provided therebetween. The apparatus also has a main wire which extends along a plane of the light source board, wherein the main wire extends between adjacent unit boards via the connecting portion such that all of the unit boards are electrically connected to each other by the main wire. The apparatus further has a branch wire for supplying electric power to the light source, the branch wire being provided in each unit board and branching from the main wire in each unit board.Type: GrantFiled: February 3, 2006Date of Patent: September 3, 2013Assignee: NEC CorporationInventors: Masahiro Ishizuka, Katsuyuki Okimura, Yoshinori Ueji, Ryuichiro Morinaka, Naoki Tatsumi, Tomoyuki Fukuda
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Patent number: 8471061Abstract: A 5-aminolevulinic acid salt which is useful in fields of microorganisms, fermentation, animals, medicaments, plants and the like; a process for producing the same; a medical composition comprising the same; and a plant activator composition comprising the same.Type: GrantFiled: March 13, 2012Date of Patent: June 25, 2013Assignee: Cosmo Oil Co., Ltd.Inventors: Naohisa Tachiya, Seiji Nishikawa, Mai Higo, Tohru Tanaka, Masahiro Ishizuka, Hideki Okada
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Publication number: 20130011337Abstract: To provide a therapeutic agent and a diagnostic agent for mitochondrial dysfunction brain diseases including cerebral infarction as a representative. A therapeutic agent for a mitochondrial dysfunction brain disease, which comprises (A) ?-aminolevulinic acid represented by the formula (1), a derivative thereof, or a salt thereof and (B) an iron compound in combination. R2R1NCH2COCH2CH2COR3 ??(1) wherein R1 and R2 each independently represents a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group, or an aralkyl group; and R3 represents a hydroxy group, an alkoxy group, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group, or an amino group.Type: ApplicationFiled: September 13, 2012Publication date: January 10, 2013Applicant: SBI PHARMACEUTICALS CO., LTD.Inventors: Toshihiko KUROIWA, Yoshinaga KAJIMOTO, Takahiro MASUBUCHI, Masahiro ISHIZUKA, Tohru TANAKA
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Patent number: 8309493Abstract: To provide a polyphenol-content-increasing agent which increases the content of polyphenol in a plant. A polyphenol-content-increasing agent for plant, containing, as an active ingredient, a 5-aminolevulinic acid or a derivative thereof represented by the following formula (1): (Chem 1) R2R1NCH2COCH2CH2COR3??(1) wherein R1 and R2 each independently represents a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group, or an aralkyl group; R3 represents a hydroxyl group, an alkoxy group which may have a substituent, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group, or an amino group, or a salt thereof.Type: GrantFiled: July 18, 2007Date of Patent: November 13, 2012Assignee: Cosmo Oil Co., Ltd.Inventors: Masao Kondo, Naomi Aiba, Setsuko Miyanari, Masahiro Ishizuka, Tohru Tanaka
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Publication number: 20120172227Abstract: A 5-aminolevulinic acid salt which is useful in fields of microorganisms, fermentation, animals, medicaments, plants and the like; a process for producing the same; a medical composition comprising the same; and a plant activator composition comprising the same.Type: ApplicationFiled: March 13, 2012Publication date: July 5, 2012Applicant: COSMO OIL CO., LTDInventors: Naohisa TACHIYA, Seiji NISHIKAWA, Mai HIGO, Tohru TANAKA, Masahiro ISHIZUKA, Hideki OKADA
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Patent number: 8173839Abstract: A 5-aminolevulinic acid salt which is useful in fields of microorganisms, fermentation, animals, medicaments, plants and the like; a process for producing the same; a medical composition comprising the same; and a plant activator composition comprising the same.Type: GrantFiled: March 28, 2005Date of Patent: May 8, 2012Assignee: Cosmo Oil Co., LtdInventors: Naohisa Tachiya, Seiji Nishikawa, Mai Higo, Tohru Tanaka, Masahiro Ishizuka, Hideki Okada
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Publication number: 20110065787Abstract: The present invention is intended to provide an agent for treating male infertility which is highly effective to male infertility, and having few side effects. To achieve the object, an agent for treating male infertility comprising ?-amino levulinic acid shown by general formula (1), its derivative or salt thereof: R2R1NCH2COCH2CH2COR3??(1) [wherein R1 and R2 independently represent a hydrogen atom, alkyl group, acyl group, alkoxycarbonyl group, aryl group, or aralkyl group; R3 represents a hydroxy group, alkoxy group, acyloxy group, alkoxycarbonyloxy group, aryloxy group, aralkyloxy group or amino group] can be used.Type: ApplicationFiled: May 13, 2009Publication date: March 17, 2011Inventors: Setsuko Miyanari, Masumi Takahashi, Masahiro Ishizuka, Tohru Tanaka
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Publication number: 20110033386Abstract: Provided is a sensitizing detection agent of an oral or intravenous administration type which enables the detection of bladder cancer with a higher sensitivity without causing pain to the patient. A sensitizing detection agent for bladder cancer comprising 5-aminolevulinic acid (ALA), a derivative thereof, or a salt of these is orally or intravenously administered, and a video camera system is inserted via the urethra and a blue light at 380-440 nm is irradiated to observe the red fluorescent part. Further, VLD-M1 is inserted and a blue light at 405 nm is irradiated to observe fluorescence intensity (relative intensity) of the red light part. For oral administration, 20 mg/kg (maximum of 1 g) of ALA is dissolved in 50 mL of a 5% glucose solution prior to the administration.Type: ApplicationFiled: April 21, 2009Publication date: February 10, 2011Inventors: Keiji Inoue, Masahiro Ishizuka
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Publication number: 20100203159Abstract: The invention provides a metal component absorption enhancer which enhances the absorption of at least one metal component selected from the elements belonging to the groups 2 to 12 in the third to fourth periods when a plant grows. An absorption enhancer of at least one metal component selected from the elements belonging to the groups 2 to 12 in the third to fourth periods in a plant, which comprises 5-aminolevulinic acid or a derivative thereof represented by the following general formula (1), or a salt thereof as an active ingredient: R2R1NCH2COCH2CH2COR3??(1) wherein R1 and R2 each independently represents a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group, or an aralkyl group; R3 represents a hydroxyl group, an alkoxy group, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group, or an amino group, and is used for performing a treatment with 0.Type: ApplicationFiled: September 5, 2007Publication date: August 12, 2010Applicant: COSMO OIL CO., LTD.Inventors: Naohisa Tachiya, Shigeyuki Funada, Masahiro Ishizuka
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Publication number: 20100173780Abstract: To provide a polyphenol-content-increasing agent which increases the content of polyphenol in a plant. A polyphenol-content-increasing agent for plant, containing, as an active ingredient, a 5-aminolevulinic acid or a derivative thereof represented by the following formula (1): (Chem 1) R2R1NCH2COCH2CH2COR3 ??(1) wherein R1 and R2 each independently represents a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group, or an aralkyl group; R3 represents a hydroxyl group, an alkoxy group which may have a substituent, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group, or an amino group, or a salt thereof.Type: ApplicationFiled: July 18, 2007Publication date: July 8, 2010Applicant: COSMO OIL CO., LTD.Inventors: Masao Kondo, Naomi Aiba, Setsuko Miyanari, Masahiro Ishizuka, Tohru Tanaka
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Publication number: 20100120916Abstract: To provide a therapeutic agent and a diagnostic agent for mitochondrial dysfunction brain diseases including cerebral infarction as a representative. A therapeutic agent for a mitochondrial dysfunction brain disease, which comprises (A) ?-aminolevulinic acid represented by the formula (1), a derivative thereof, or a salt thereof and (B) an iron compound in combination. R2R1NCH2COCH2CH2COR3 ??(1) wherein R1 and R2 each independently represents a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group, or an aralkyl group; and R3 represents a hydroxy group, an alkoxy group, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group, or an amino group.Type: ApplicationFiled: March 27, 2008Publication date: May 13, 2010Applicant: SBI ALAPROMO CO., LTD.Inventors: Toshihiko Kuroiwa, Yoshinaga Kajimoto, Takahiro Masubuchi, Masahiro Ishizuka, Tohru Tanaka
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Publication number: 20080108701Abstract: According to the present invention, a tumor diagnostic agent which carries out early stage detection, monitoring of therapeutic effect and prognostic diagnosis of all tumors The tumor diagnostic agent of the present invention is a tumor diagnostic agent comprising ?-aminolevulinic acid represented by formula (I), a derivative thereof and a salt thereof: R2R1NCH2COCH2CH2COR3 ??(I) wherein R1 and R2 each independently represents hydrogen, alkyl, acyl, alkoxycarbonyl, aryl or aralkyl; and R3 represents hydroxy, alkoxy, acyloxy, alkoxycarbonyloxy, aryloxy, aralkyloxy or amino, which is used for diagnoses by measuring porphyrins in a sample collected from the inside or outside of the body after its administration.Type: ApplicationFiled: September 22, 2005Publication date: May 8, 2008Applicant: Cosmo Oil Co., LtdInventors: Ichiro Okura, Toshiaki Kamachi, Shunichiro Ogura, Masahiro Ishizuka, Tohru Tanaka
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Publication number: 20080026075Abstract: Health function-improving agents, such as an immunological function-improving agent, an antioxidation function-improving agent, a exercise function-improving agent and a liver function-improving agent, comprising, as an effective ingredient, a ?-amino acid, a derivative thereof or a salt thereofType: ApplicationFiled: August 26, 2005Publication date: January 31, 2008Applicant: Cosmo Oil Co., Ltd.Inventors: Masao Kondo, Naomi Aiba, Setsuko Miyanari, Tohru Tanaka, Takaya Suzuki, Masahiro Ishizuka
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Publication number: 20070203027Abstract: A 5-aminolevulinic acid salt which is useful in fields of microorganisms, fermentation, animals, medicaments, plants and the like; a process for producing the same; a medical composition comprising the same; and a plant activator composition comprising the same.Type: ApplicationFiled: March 28, 2005Publication date: August 30, 2007Inventors: Naohisa Tachiya, Seiji Nishikawa, Mai Higo, Tohru Tanaka, Masahiro Ishizuka, Hideki Okada
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Publication number: 20060221608Abstract: A flat light source apparatus has a light source board which comprises unit boards, each unit board having a printed circuit board and a light source formed on the printed circuit board, wherein the unit boards are arranged adjacent to each other at least in one direction, and any pair of the unit boards adjacent to each other is integrated by a connecting portion provided therebetween. The apparatus also has a main wire which extends along a plane of the light source board, wherein the main wire extends between adjacent unit boards via the connecting portion such that all of the unit boards are electrically connected to each other by the main wire. The apparatus further has a branch wire for supplying electric power to the light source, the branch wire being provided in each unit board and branching from the main wire in each unit board.Type: ApplicationFiled: February 3, 2006Publication date: October 5, 2006Inventors: Masahiro Ishizuka, Katsuyuki Okimura, Yoshinori Ueji, Ryuichiro Morinaka, Naoki Tatsumi, Tomoyuki Fukuda
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Patent number: 7084885Abstract: An example image display apparatus includes processing circuitry such as a communication processor and a game processor. The processing circuitry continuously processes a communication-related function and selectively processes a game-related function. When the game function is in an off-state, binary image data and color image data for the communication-related function are written to a first memory and to a second memory, respectively. When the game function is set to an on-state, color image data for the game-related function is written to the second frame memory instead of the color image data for the communication-related function. A display includes a composite image based on the binary image data stored in the first memory and the color image data stored in the second memory.Type: GrantFiled: November 28, 2001Date of Patent: August 1, 2006Assignee: Nintendo Co., Ltd.Inventors: Satoru Okada, Masahiro Ishizuka, Takuma Matsunada, Tsuyoshi Kiyuna
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Patent number: 7069044Abstract: An electronic apparatus includes a phone CPU and a game CPU. When a * key is operated during execution of a game, the phone CPU sets a specified bit of a game key register to “1”. The phone CPU is set “1” into the specified bit when there is an incoming call of a phone during the execution of the game. The game CPU pauses the game being in execution when the specified bit is renewed to “1” and restores the specified bit from “1” to “0”. When the * key is operated in a state the game is interrupted, the phone CPU sets “1” into the specified bit. The game CPU restarts the game by canceling the pause.Type: GrantFiled: November 27, 2001Date of Patent: June 27, 2006Assignee: Nintendo Co., Ltd.Inventors: Satoru Okada, Masahiro Ishizuka, Takuma Matsunada, Tsuyoshi Kiyuna
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Publication number: 20030098821Abstract: An image display apparatus includes a phone CPU and a game CPU. The phone CPU processes a phone function being continuously set into an on state, and the game CPU processes a game function being set into an on state in case of necessity. When the game function is in an off state, binary image data and color image data relating to the phone function are written to a first frame memory and a second frame memory, respectively. When the game function is set into an on state, the color image data relating to the game function is written to the second frame memory in place of the color image data relating to the phone function. A composite image based on the binary image data stored in the first frame memory and the color image data stored in the second frame memory is displayed on an LCD.Type: ApplicationFiled: November 28, 2001Publication date: May 29, 2003Inventors: Satoru Okada, Masahiro Ishizuka, Takuma Matsunada, Tsuyoshi Kiyuna
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Publication number: 20030100347Abstract: An electronic apparatus includes a phone CPU and a game CPU. When a *key is operated during execution of a game, the phone CPU sets a specified bit of a game key register to “1”. The phone CPU is set “1” into the specified bit when there is an incoming call of a phone during the execution of the game. The game CPU pauses the game being in execution when the specified bit is renewed to “1” and restores the specified bit from “1” to “0”. When the *key is operated in a state the game is interrupted, the phone CPU sets “1” into the specified bit. The game CPU restarts the game by canceling the pause.Type: ApplicationFiled: November 27, 2001Publication date: May 29, 2003Inventors: Satoru Okada, Masahiro Ishizuka, Takuma Matsunada, Tsuyoshi Kiyuna