Patents by Inventor Masakuni Okuhara

Masakuni Okuhara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for immunosuppression
    Patent number: 4929611
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Grant
    Filed: May 30, 1986
    Date of Patent: May 29, 1990
    Assignee: Fujisawa Pharmaceutical Company, Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • New compounds WF 2015 A and B
    Patent number: 4910017
    Abstract: This invention relates to new compounds WF 2015 A and B which have immunosuppressing activity and antitumor activity, to a process for producing WF 2015 A and B by culturing a WF 2015 A and/or B-producing strain belonging to the genus Scolecobasidium in a nutrient medium, and to a pharmaceutical composition comprising the same.
    Type: Grant
    Filed: October 25, 1988
    Date of Patent: March 20, 1990
    Assignee: Fujisawa Pharmaceutical Company, Ltd.
    Inventors: Takanao Otsuka, Toshihiro Shibata, Hiroshi Terano, Yasuhisa Tsurumi, Masakuni Okuhara
  • Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
    Patent number: 4894366
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Grant
    Filed: November 20, 1985
    Date of Patent: January 16, 1990
    Assignee: Fujisawa Pharmaceutical Company, Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Antitumor agent comprising FR-900216
    Patent number: 4680178
    Abstract: The invention relates to a pharmaceutical composition for treating lymphocytic leukemia, melanoma or mammary carcinoma comprising an effective amount of FR-900216.
    Type: Grant
    Filed: July 16, 1984
    Date of Patent: July 14, 1987
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Sumio Kiyoto, Masakuni Okuhara, Eiko Kino, Hirokazu Tanaka, Hatsuo Aoki, Masanobu Kohsaka, Hiroshi Imanaka
  • Antibiotic phosphonic acid derivatives and production and use thereof
    Patent number: 4143135
    Abstract: An antibiotic FR-900098 which has been assigned the chemical structure ##STR1## and another antibiotic FR-33289 which has been assigned the chemical structure ##STR2## have been isolated from cultured broths.
    Type: Grant
    Filed: July 27, 1977
    Date of Patent: March 6, 1979
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Yoshio Kuroda, Masakuni Okuhara, Eiko Iguchi, Hatsuo Aoki, Hiroshi Imanaka