Abstract: A model animal causing the white hair development as a non-human mammalian animal with a phenotype such that the color of the hair first growing after birth is black or almost black and the model animal then causes the spontaneous white hair development following aging, where (1) the activated RET gene is genetically inserted in a hetero form and (2) the endothelin receptor B (Ednrb) gene is deficient in a hetero form, or the Ednrb gene is deficient in the homo form or in a hetero form and the Ednrb gene is genetically inserted in the homo form or in a hetero form under the DbH promoter. In accordance with the invention, there is provided a model animal causing the white hair development, which is the most suitable for research works about the mechanism of the white hair development and research works about a pharmaceutical preparation or a treatment capable of preventing the white hair development.

Abstract: A compound represented by formula (I) (wherein ring A is a nitrogen-containing ring which may have a substituent(s), E is a binding bond or a spacer of which main chain has an atom number of 1-8, Q is a hydrogen atom, a hydrocarbon group which may have a substituent(s) or a cyclic group which may have a substituent(s).), a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof. Since the compounds of the present invention represented by formula (I), a salt thereof, an N-oxide thereof or a solvate thereof, or a prodrug thereof have the affinity to MBR, they are useful for the prevention and/or treatment for disease caused by stress.

Abstract: The present invention relates to the compounds of the formula (I) and salts thereof (all the symbols are the same meanings as described in the specification). The compounds of the formula (I) possess inhibitory activity of N-type calcium channel, so they are useful as drug for prevention and/or treatment of cerebral infarct, transient ischemic attack, encephalomyelopathy after cardiac operation, spinal angiopathy, hypertension with stress, neurosis, epilepsy, asthma and pollakiuria etc. or agent for the treatment of pain.

Abstract: An image forming apparatus comprising: a determining unit which determines a start time for forming an image on a recording medium; a judging unit having a first judging unit which judges whether to execute a quality improving process based on the start time; and a control unit which controls an execution of the quality improving process based on a judgment result of the first judging unit.

Abstract: The present application relates to an eyepiece for use with a viewing device. The eyepiece is configured to change the distance between a first edge of the eyepiece and a lens near a second edge of the eyepiece. The eyepiece includes a first element having a pin extending therefrom and a rotational axis having a first axial direction and a second axial direction. The eyepiece further includes a second element having a groove, the second element sharing the rotational axis and configured to rotate about the rotational axis relative to the first element. The groove comprises a first pin movement section and a second pin movement section. The groove further comprises a pin stopping section, the pin stopping section located between the first pin movement section and the second pin movement section. The pin stopping section is configured to prevent the second element from rotating relative to the first element.

Abstract: An object of the present invention is to provide a silver powder which is an unprecedentedly fine particulate silver powder and has a dispersibility more approximate to monodispersibility resulting less aggregation. To achieve the above object, a fine particulate silver powder having unprecedented powder properties in which: a. the average particle diameter DIA of the primary particles obtained by image analysis of a scanning electron micrograph is 0.6 ?m or less; b. the crystallite diameter is 10 nm or less; and c. the sintering starting temperature is 240° C.

Abstract: The present invention relates to the compound represented by formula (I): (wherein, all the symbols has the same meanings as that of the specification), a salt thereof, a solvate thereof or a prodrug thereof. Since the compound of the present invention has an anti stress action, it is useful for preventive and/or therapeutic agent for a disease caused by stress, especially a digestive system disease caused by stress and is superior to oral absorption.

Abstract: The present invention relates to the compound presented by formula (I) (wherein all symbols in formula (I) are the same mean as the description shown in the specification.), mitocondorial benzogeazepin receptor (MBR) antagonist comprising the compound, the preventive and/or treatment medicine against diseases caused by stress of which an active ingredient is the compound. Since the compound represented by formula (I) has MBR antagonistic activity, and controls the production of neurosteroid, it is useful as the preventive and/or treatment medicine against diseases caused by stress.

Abstract: A control lever may be prevented from moving from a particular shift position when a shift lever is moved from a particular shift position in an automated gear change mode selection area, and a coupled state with the shift lever has been released. In a shift lever device, when a shift lever moves from the D position that is in an automatic gear change area to a manual gear change area, coupled to this movement, a striker plate slides along a width direction from a released position to a constrained position. In doing so, a stopper member prevents movement along a shift direction of the striker plate that is in the constrained position, preventing movement along the shift direction of a support lever, which has been integrated to the striker plate moving in the shift direction, and the shift lever.

Abstract: An image forming apparatus includes: a connector unit to which an external memory device is connected; a detecting unit configured to detect whether the external memory device is connected to the connector unit or not and output a detection result indicating that the connector unit is in a connected state or an unconnected state; a printing unit configured to execute a printing according to data from the external memory device connected to the connector unit; and a suspending unit configured to suspend operation of the printing unit according to a predetermined timing in response to a change in the detection result from the connected state to the unconnected state.

Abstract: The present invention relates to the compounds of the formula (I) and salts thereof (all the symbols are the same meanings as described in the specification). The compounds of the formula (I) possess inhibitory activity of N-type calcium channel, so they are useful as drug for prevention and/or treatment of cerebral infarct, transient ischemic attack, encephalomyelopathy after cardiac operation, spinal angiopathy, hypertension with stress, neurosis, epilepsy, asthma and pollakiuria etc. or agent for the treatment of pain.

Abstract: An image forming apparatus includes: a memory connecting portion, to which an external memory is detachably connected; a detecting portion that detects a connection state of the external memory; a printing portion that prints an image based on an image file to be printed which is stored in the external memory; and a controller that performs an automatic printing processing in which the controller controls the printing portion to automatically start printing the image in response to a detection by the detecting portion of connection of the external memory to the memory connecting portion.

Abstract: An image forming apparatus includes: a first designation portion which designates a directory from plural directories stored in a storage medium; a first printing portion which index prints images on a first print medium based on files stored in the directory designated by the first designation portion, the files including at least one of an image data file and a sub-directory; a display portion; a first display control portion which controls the display portion to display information for designating the files after the images are index-printed by the first printing portion; a second designation portion which designates one of the files based on the information displayed on the display portion; and a second printing portion which prints an image on a second print medium based on the designated one of the files.

Abstract: An image forming apparatus that can read data from a storage medium having hierarchically structured directories including a first directory and a second directory which is stored in the first directory. The apparatus includes: a display portion that displays designation information of the first directory; a designation portion that designates the second directory based on the first directory designation information displayed on the display portion; a display control portion that controls the display portion to display designation information of the second directory when the second directory is designated by the designation portion; and a printing portion that index-prints images on a print medium based on files stored in one of the first and second directories, the designation information of which is currently displayed on the display portion.

Abstract: There is provided an image processing device, which comprises an interface into which a removal storage medium can be connected; at least one device having one of an image reading function and an image output function; a preparation control unit configured to execute a preparation process so that the at least one device moves from a first state corresponding to a non-ready state and a second state corresponding to a ready state; and an image process unit having at least one of a function of storing image data and a function of reading image data; a detection unit configured to detect whether the removal storage medium is connected to the interface; and a controller configured to move the at least one device to the second state in response to detection of insertion of the removal medium into the interface by the detection unit.

Abstract: A printing apparatus to make a number of copy of a printed material on which an image is formed according to print data stored in a removable memory medium is provided. The printing apparatus includes an interface to which the removable memory medium is connected so that the print data stored in the removable memory medium is inputted to the printing apparatus, a printable number detecting system, which is configured to detect a number of copy of the printed material to be made being stored in the removable memory medium, a printing system, which is configured to make the printed material, and a controlling system, which is configured to control a total of the number of copy of the printed material to be made by the printing system.

Abstract: The compound represented by formula (I) (wherein D and G are cyclic group which may have a substituent(s) or alkyl which may have a substituent(s), W and Y are a bond or a spacer of which main chain has an atom number of 1-4, ringA and ringB are heterocyclic ring which may have a substituent(s), containing at least one carbon atom and one nitrogen atom and the ringA and ringB share one spiro carbon atom), a salt thereof, an N-oxide thereof or a solvate thereof, or a prodrug thereof. Since the compounds represented by formula (I), a salt thereof, an N-oxide thereof or a solvate thereof, or a prodrug thereof have the affinity to MBR, they are useful for the prevention and/or treatment for disease caused by stress.

Abstract: An image forming device includes a display, a reading unit, a display controlling unit, and an operating unit. The reading unit reads at least one file stored in a removable memory. The display controlling unit displays on the display a first selection item together with at least one second selection item. The first selection item is used for performing index printing for the at least one file. The at least one second selection item is used for printing each of the at least one file. Each of the at least one second selection item corresponds to one of the at least one file. The operating unit is capable of selecting one of the first selection item and the at least one second selection item.

Abstract: A peripheral device has a mounting portion and a storage unit. The mounting portion is configured to mount a removable storage. The storage unit is configured to store data. The reading out unit reads out specific information from the removable storage medium when the removable storage medium is mounted to the mounting portion. The deletion unit deletes at least part of the data in the storage unit based on the specific information read out by the reading out unit.

Abstract: A duplicate setting prevention system for an image processing apparatus includes a setting file, a set of history information, a determination unit, a setting unit, a prohibiting unit, and a history information recording unit. The setting file is stored in a removable memory removably mounted on an image processing apparatus and is for setting the image processing apparatus. The set of history information is stored in the removable memory and indicates that the image processing apparatus has been set based on the setting file. When the removable memory is mounted on the image processing apparatus, the determination unit reads out the history information set and determines that a setting has been performed to the image processing apparatus based on the setting file. The setting unit performs the setting to the image processing apparatus based on the setting file.