Abstract: Provided herein is 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile, or an enantiomer, a mixture of enantiomers, a tautomer, or a pharmaceutically acceptable salt thereof, and methods for treating, preventing or managing multiple myeloma using such compounds. Also provided are pharmaceutical compositions comprising the compounds, and methods of use of the compositions.

Abstract: System and methods for dynamic replenishment in a facility are disclosed. A mobile inventory processing device reads a machine readable tag affixed to a perishable item and transmits an indication of the perishable item to a stock inventory processing device. The stock inventory processing device retrieves a stock inventory value corresponding to the perishable item and a historic daily sales value for the perishable item from a database. The stock inventory processing device determines a restocking value based on whether the historic daily sales value exceeds the stock inventory value. The stock inventory processing device transmits a second indication to the mobile inventory processing device, The second indication correspond to insufficient shelf stock of the perishable item. The mobile inventory processing device receives the second indication and outputs an auditory alert in response to the second indication.

Abstract: Provided herein is 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile, or an enantiomer, a mixture of enantiomers, a tautomer, or a pharmaceutically acceptable salt thereof, and methods for treating, preventing or managing multiple myeloma using such compounds. Also provided are pharmaceutical compositions comprising the compounds, and methods of use of the compositions.

Abstract: In some embodiments, systems, apparatuses and methods are described herein useful to indicate the number of products on a merchandising unit. Counting devices as described herein maintain an accurate count of the number of products on a given merchandising unit and provides a display of the count.

Abstract: Compounds of formula A-I and B-I, compositions comprising the compounds, methods of making the compounds and methods of their uses are disclosed.

Abstract: Compounds of formula A-I and B-I, compositions comprising the compounds, methods of making the compounds and methods of their uses are disclosed.

Abstract: Provided herein is 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile, or an enantiomer, a mixture of enantiomers, a tautomer, or a pharmaceutically acceptable salt thereof, and methods for treating, preventing or managing multiple myeloma using such compounds. Also provided are pharmaceutical compositions comprising the compounds, and methods of use of the compositions.

Abstract: Systems and methods described herein relate to scheduling and coordination of particular tasks based upon dynamically updated product inventory data. These systems and methods increase the efficiency of stocking and fulfillment as well as inventory auditing of the inventory.

Abstract: Compounds of formula A-I and B-I, compositions comprising the compounds, methods of making the compounds and methods of their uses are disclosed.

Abstract: A shelving system is provided, which includes a plurality of supports, each support of the plurality of supports having a longitudinal opening defining a channel extending from a first end to a second end of the support, the plurality of supports having at least one opening positioned on a surface of the plurality of supports, at least one shelf, the at least one shelf including an extension, the extension being positioned within the channel of each of the plurality of supports to allow a vertical movement of the at least one shelf with respect to the plurality of supports; and an actuator operably coupled to the at least one shelf, wherein actuation of the actuator permits the vertical movement of the at least one shelf within the channel. Furthermore, an associated method is also provided.

Abstract: Compounds of formula A-I and B-I, compositions comprising the compounds, methods of making the compounds and methods of their uses are disclosed.

Abstract: In some embodiments, apparatuses and methods are provided herein useful to the sortation of products using a conveyor assembly.

Abstract: In some embodiments, apparatuses, systems, and methods are provided herein for front-facing merchandise in a shopping facility. A system for front-facing products includes a product display surface having a customer-facing portion, wherein a plurality of products are positioned on the product display surface, a control unit, and a product movement unit coupled to and under control of the control unit, wherein the product movement unit is configured to provide a force sufficient to induce movement of at least one product relative to the product display surface, the product display surface being substantially stationary during the movement, wherein the movement is in a direction toward the customer-facing position, and wherein the control unit is configured to receive a signal instructing activation of the product movement unit and output an activation signal to the product movement unit.

Abstract: Compounds of formula A-I and B-I, compositions comprising the compounds, methods of making the compounds and methods of their uses are disclosed.

Abstract: The present invention describes compounds, processes for their preparation, pharmaceutical compositions containing them, and their use in therapy.

Abstract: The present invention describes compounds of the formula pharmaceutically acceptable salts thereof, processes for their preparation, pharmaceutical compositions containing them, and their use in therapy.

Abstract: The present invention describes compounds, processes for their preparation, pharmaceutical compositions containing them, and their use in therapy.

Abstract: The present invention describes compounds, processes for their preparation, pharmaceutical compositions containing them, and their use in therapy.

Abstract: The present invention describes compounds, processes for their preparation, pharmaceutical compositions containing them, and their use in therapy.