Abstract: A seal member is configured to seal a chamber of a drug delivery device which is suitable to contain a drug, wherein the seal member comprises a diaphragm.

Abstract: The invention refers to a finger guard for an injection device with a hollow injection needle arranged to be hidden inside a component with an orifice prior to use and to be advanced relative to the component through the orifice for inserting it into an injection site, the finger guard comprising a spring wire attached to the component and comprising an arcuate transversal section biased in a manner to flex inwards so as to essentially obstruct the orifice for finger access when released but staying enough off-centre to allow the needle to advance through the orifice without touching the spring wire.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is presented having an elongate case arranged to be held by a user, a tubular chassis telescoped in the case and biased against the case so as to protrude from the case. The injector also includes a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe. A trigger button is distally arranged in or on the case, wherein the trigger button is initially coupled to the case in a manner to protrude distally from the case and interlocked to the chassis in a manner preventing the trigger button from disengaging the case.

Abstract: The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, wherein the syringe is slidably arranged with respect to the housing, spring means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, operating the syringe to supply the dose of medicament, and retracting the syringe with the needle into the covered position after delivering the medicament, activating means. The spring means is a single drive spring arranged to be grounded at a distal end in the housing for advancing the needle and for injecting the dose of medicament via a plunger. The drive spring has its ground in the housing switched to its proximal end for retracting the syringe. An interlock sleeve is telescoped in the proximal end of the housing.

Abstract: The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site, wherein the syringe is slidably arranged with respect to the housing, spring means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, operating the syringe to supply the dose of medicament, and retracting the syringe with the needle into the covered position after delivering the medicament, activating means arranged to lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is presented having a tubular chassis telescopable in an elongate chassis, a carrier subassembly comprising a tubular carrier slidably arranged partially inside the chassis and inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier.

Abstract: An auto-injector for administering a dose of a liquid medicament is presented that has a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier adapted to contain a syringe with a hollow injection needle. The injector has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. There is also a trigger button arranged distally or laterally in or on the case, a control spring arranged around the carrier, and a needle extension control mechanism for coupling a proximal end of the control spring to either the carrier for advancing it for needle extension or to the chassis for needle retraction depending on the relative axial position of the carrier and the chassis.

Abstract: The invention refers to a shuttering mechanism (1) for controlling translation of a longitudinally moveable component (2) within a housing (4), the shuttering mechanism (1) comprising at least one fixed shutter (3) attached to or integrated with the housing (4) and at least one moving shutter arm (7) moveable between at least one locking position and at least one unlocking position, wherein at least one resilient arm (5) is associated with the longitudinally moveable component (2), the resilient arm (5) having a dog (6) resiliently biased towards the fixed shutter (3), wherein the moving shutter arm (7) is arranged alongside the fixed shutter (3), wherein at least one fixed protrusion (3.1 to 3.n) is arranged on the fixed shutter (3) at least one of them arranged for engaging the dog (6) so as to prevent translation of the longitudinally moveable component in a proximal direction (P), wherein at least one moving protrusion (7.1 to 7.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is presented having an elongate case, a carrier subassembly comprising a tubular carrier slidably arranged inside the case, where the carrier adapted to contain a syringe with a hollow injection needle. The injector also has, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for advancing the needle beyond a proximal end of the auto-injector, and a trigger button is used for releasing the control spring on actuation.

Abstract: The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site, wherein the syringe is slidably arranged with respect to the housing, spring means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, operating the syringe to supply the dose of medicament, and retracting the syringe with the needle into the covered position after delivering the medicament, activating means arranged to lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection.

Abstract: The invention relates to a detent mechanism for controlling translation between two components in a longitudinal direction (P, D), the detent mechanism comprising at least one clip on one of the components arranged to be in a ramped engagement with a recess in the other one of the components in an initial state in such a manner that translation between the components is constrained and that application of a translative force between the components in one longitudinal direction (P, D) with the clip engaged with the recess deflects the clip out of the recess when a predetermined value of the translative force, at least depending on the resilience of the clip, is overcome so as to allow translation between the components.

Abstract: According to the invention, a safety device for a pre-filled syringe comprises of a support body adapted to mount the pre-filled syringe, a first needle shield slidably arranged with respect to the support body and a second needle shield slidably arranged with respect to the support body and releasably retained in a retracted position (PR). A proximal movement of the first needle shield with respect to the support body releases the retention of the second needle shield in the retracted position (PR), so that the second needle shield is allowed to slide in the distal direction towards an advanced position (PA).

Abstract: The invention refers to a shuttering mechanism for controlling translation of a longitudinally moveable component within an elongate housing, the shuttering mechanism comprising at least one set of castellations on the housing and at least one resilient arm associated with the longitudinally moveable component, the resilient arm having a dog resiliently biased towards the castellations so as to engage between or behind the castellations and block the translation, wherein a respective shutter arm is arranged alongside the set of castellations, the shutter arm having a number of consecutive ramped protrusions spaced from each other, wherein the castellations and the ramped protrusions have the same pitch, wherein a profiled surface is formed by the castellations and the ramped protrusions, wherein the shutter arm is moveable in longitudinal direction with respect to the set of castellations, wherein the shutter arm has at least one locking position with its ramped protrusions essentially in phase with the caste

Abstract: The invention refers to an auto-injector for delivering a liquid medicament, comprising: an elongate housing arranged to contain a syringe with a hollow injection needle and a stopper, wherein the syringe is slidably arranged with respect to the housing, spring means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position for insertion into the injection site, operating the syringe to inject the dose of medicament, and advancing a needle shroud over the needle for providing needle safety, activating means arranged to lock and release the spring means, wherein the spring means is a single drive spring in the shape of a compression spring grounded distally in the housing and proximally bearing against a thrust collar arranged to transmit load from the spring means via a plunger to the syringe and/or the stopper for needle insertion and injection, wherein the plunger is engageable to the thrust collar for joint axial translation, wherein the plunge

Abstract: The invention refers to a needle safety arrangement for protecting a hollow injection needle of a syringe after an injection, the needle safety arrangement comprising: a needle sheath having essentially the shape of a hollow cylinder arranged to surround the needle, the needle sheath slidable in longitudinal direction with respect to the syringe and biased in proximal direction (P), a sheath linkage, slidable in longitudinal direction, a syringe carrier for holding the syringe, the syringe and syringe carrier arranged for joint axial translation and rotation relative to the needle sheath, wherein the sheath linkage comprises means for restricting translation in proximal direction (P) with respect to the syringe by abutting against the syringe carrier, wherein in an initial state the sheath linkage is abutted against the syringe carrier and latched to the needle sheath for joint axial translation, wherein the syringe carrier exhibits at least one cam on its circumference, wherein the cam is arranged to de-l

Abstract: According to the invention, a safety device for a pre-filled syringe comprises a hollow support body for retaining the pre-filled syringe, a hollow needle shield that is movable relative to the support body from a first position to a second position, releasable mounting means to mount the pre-filled syringe within the support body and a spring means arranged within the support body in a non-energized or only slightly energized state. The movement of the needle shield from the first position to the second position fully energizes the spring means.

Abstract: The invention refers to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the elongate housing having a distal end and a proximal end with an orifice intended to be applied against an injection site, wherein the syringe is slidably arranged with respect to the housing, spring means capable of, upon activation, pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, operating the syringe to supply the dose of medicament, and covering the needle on removal of the auto-injector from the injection site, activating means arranged to lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection, characterized in that the spring means is a torsion spring, wherein a first gear arrangemen

Abstract: The invention refers to an auto-injector comprising an elongate housing, a syringe with a hollow injection needle and a stopper, wherein the syringe is arranged in a syringe carrier slidably with respect to the housing, a single compression spring capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end for insertion into an injection site, operating the syringe to inject the dose of medicament, and retracting the syringe with the needle into the covered position after at least partially delivering the medicament, activating means arranged to lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the compression spring for injection.

Abstract: The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate housing, a syringe with a hollow needle and a bung for displacing the medicament, wherein the syringe is slidably arranged with respect to the housing, spring means for pushing the needle from a covered position inside the housing into an advanced position past the proximal end and for supplying the dose of medicament, activating means for locking and releasing the spring means. The spring means is a torsion spring grounded at one end in the housing and at the other end in a lead nut rotatable about a longitudinal axis but axially constrainable. The lead nut is arranged for translatively moving a piston rod by means of a lead screw thread. The piston rod is prevented from rotating relative to the housing and arranged to be coupled to the bung in order to push it forwards.