Abstract: An auto-injector for administering a dose of a liquid medicament includes an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site. The syringe is slidably arranged with respect to the housing. A spring capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, operating the syringe to supply the dose of medicament, and retracting the syringe with the needle into the covered position. After delivering the medicament, an activator arranged to lock the spring in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring for injection.

Abstract: The invention refers to an auto-injector for administering a dose of a liquid medicament (M), the auto-injector having a distal end (P) and a proximal end (D) with an orifice intended to be applied against an injection site and comprising: an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament (M), wherein the syringe (3) is slidably arranged with respect to the housing, a drive means capable of, upon activation: pushing the needle from a retracted position into an advanced position through the orifice and past the proximal end (P), and operating the syringe to supply the dose of medicament (M), a plunger for transmitting power from the drive means to the syringe and/or stopper, activating means arranged to lock the drive means in a compressed state prior to manual operation and capable of, upon manual operation, releasing the drive means for injection, characterized in that translation of the needle and the syringe and/

Abstract: An Injection device for administering a dose of liquid medicament to patient comprises—a syringe containing the dose of medicament—a hollow injection needle adapted to penetrate skin of the patient, —a stopper translatably disposed within syringe, —a plunger connectable to stopper and translatable in at least a proximal direction to displace stopper in the proximal direction and—a releasable noise component capable of, upon release, generating an audible and/or tactile feedback. The proximal displacement of stopper causes the dose of the medicament to be expelled through the hollow injection needle. The noise component is released when the plunger reaches a position relative to the syringe in which stopper is located in proximity of a proximal end of the syringe. The released noise component impacts on at least one component of the injection device to generate the audible and/or tactile feedback indicating the end of the injection.

Abstract: According to the invention a safety device for a pre-filled syringe comprises a substantially cylindrical and hollow support body and a hollow needle shield slideably arranged relative to the support body. The support body comprises at least one resilient arm and the hollow needle shield or a needle shield assembly comprises at least one curved actuation ramp. The curved actuation ramp protrudes in a lateral direction (L) perpendicular to a central axis (A) of the safety device. The curved actuation ramp comprises a first lateral dimension (L1) at a proximal end of the needle shield and a second lateral dimension (L2) exceeding the first lateral dimension (L1) at a distal end of the needle shield. The resilient arm engages the curved actuation ramp when the needle shield is slid relative to the support body.

Abstract: The invention relates to a front end for an auto-injector, the front end comprising a syringe with an injection needle and a stopper, wherein the syringe is slidably arranged within a syringe retainer, wherein an outer sleeve for preventing access to the needle is removably arrangeable over the syringe retainer, wherein the syringe retainer comprises a screw thread for connecting it to a correspondent screw thread of a mounting of a re-usable auto-injector back end comprising a drive means for advancing the syringe and needle in a proximal direction for needle insertion and for advancing the stopper within the syringe for injection, wherein a resilient locking barb is arranged to rotationally lock the syringe retainer to the mounting in an unscrewing direction when the front end is screwed to the re-usable back end and when the outer sleeve is removed, wherein the outer sleeve is arranged to unlock the resilient locking barb when arranged over the syringe retainer.

Abstract: According to the invention, an adaptor means for use in combination with a pre-filled syringe and a safety device for the pre-filled syringe is adapted to affix the pre-filled syringe thereto, whereby the adaptor means engages a barrel of the pre-filled syringe. The adaptor means comprises at least one locking projection that is adapted to lock the adaptor means to the safety device.

Abstract: Described is a syringe carrier comprising a body adapted to receive a barrel of a syringe. The body includes an annular groove formed in a distal end and adapted to receive a circlip disposed in a circumferential gap between the barrel of the syringe and a needle shield covering a needle of the syringe.

Abstract: The invention refers to an auto-injector and to a method for operating it, the auto-injector comprising of a tubular chassis; a carrier subassembly comprising a tubular carrier slidably arranged in the chassis, the carrier containing a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe; a wrap-over trigger sleeve arranged over the distal end (D) of the auto-injector; the trigger sleeve extending at least almost over the whole length of the auto-injector; a control spring arranged around the carrier; first interlock means for coupling a proximal end of the control spring to either the carrier for advancing it for needle insertion or to the chassis for needle retraction; second interlock means arranged for releasing the drive spring for injection; third interlock means arranged for coupling the chassis to the carrier for joint axial translation relative to the trigger sleeve; and fourth interlock means arranged for coupling a

Abstract: According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe; a syringe retainer slidably arranged with respect to the housing that mounts a pre-filled syringe with an injection needle, a plunger and a stopper for sealing a syringe barrel of the pre-filled syringe; a coupling shroud slidably arranged within the housing and releasably coupled to the plunger; and a single drive means. Upon release, the single drive means is capable of driving the coupling shroud in the proximal direction (P).

Abstract: An auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe with an injection needle, a plunger and a stopper for sealing a syringe barrel and a drive means releasably coupled to the plunger for advancing the syringe in the proximal direction (P) for needle insertion into an injection site and for displacing the dose of medicament (M) into the injection site. The drive means is arranged to be decoupled from the plunger for advancing a needle shroud to a safe position (PS) to surround the injection needle after the injection. According to the invention, the drive means bears against a thrust collar arranged to be releasably coupled to the plunger through a ramped engagement of a first tongue and a first recess so as to rotate the thrust collar on translation in proximal direction (P).

Abstract: The invention refers to an auto-injector for administering a dose of a liquid medicament, comprising: an outer casing, a syringe with a hollow needle and a stopper a torsion spring and a gear arrangement for inserting the needle, delivering the medicament, and retracting the syringe after injection. At least one skin contact trigger element is arranged at a proximal end of the outer case, the skin contact trigger element translatable in longitudinal direction between a proximal position and a distal position and biased in proximal direction in a manner to protrude from the outer casing in the proximal position, wherein in its proximal position the skin contact trigger element is arranged to prevent the spring means from being released and wherein the skin contact trigger element in its distal position is arranged to allow release of the spring means.

Abstract: According to the invention, a safety device for a pre-filled syringe comprises of a needle shield adapted to cover an injection needle of the pre-filled syringe before and after an injection, a support body with at least one pivoting arm adapted to engage a barrel collar of the pre-filled syringe and an outer body with a first inner sleeve comprising a bevelled section. The needle shield, the support body and the outer body are telescopically arranged. The needle shield, the support body and the outer body may telescope with respect to each other to cover and to expose the injection needle of the pre-filled syringe. The bevelled section is arranged to abut against the pivoting arm connected to the support body by a living hinge to deflect the pivoting arm radially inwards, so that the pivoting arm may engage the barrel collar after a dose of a medicament contained in the pre-filled syringe has been disposed beneath the skin of a patient receiving the injection.

Abstract: An auto-injector for administering a dose of a liquid medicament comprising an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site. The syringe is slidably arranged with respect to the housing. A spring capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P), operating the syringe to supply the dose of medicament (M), and retracing the syringe with the needle into the covered position. After delivering the medicament, an activator arranged to lock the spring in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring for injection.

Abstract: An auto-injector with an interlock mechanism for defining an operation sequence of the auto-injector in a manner to allow a lateral trigger button to be operated only when a proximal end of the auto-injector is pressed against an injection site.

Abstract: The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising a housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site, wherein the syringe is slidably arranged with respect to the housing, drive means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, and operating the syringe to supply the dose of medicament, and activating means arranged to lock the drive means in a loaded state prior to manual operation and capable of, upon manual operation, releasing the drive means for injection, characterized in that the drive means is at least one spring essentially transversally arranged with respect to a longitudinal axis of the syringe at least when in the loaded state.

Abstract: The invention relates to a detent mechanism for controlling translation between two components in a longitudinal direction, the detent mechanism comprising a resilient beam on one of the components and a rhomboid ramp member on the other component, the resilient beam being essentially straight when relaxed and having a first beam head and arranged to interact in a ramped engagement with respectively one of two ramps, each ramp on one longitudinal side of the rhomboid ramp member in such a manner that application of a translative force between the components in one longitudinal direction with the first beam head engaged to one of the ramps in a first state deflects the resilient beam in one transversal direction when a predetermined value of the translative force, at least depending on the resilience of the resilient beam, is overcome so as to allow the first beam head to travel along one transversal side of the rhomboid ramp member on continued relative translation of the components, wherein the resilient bea

Abstract: An auto-injector comprising an elongate housing arranged to contain a syringe and displacing medicament, wherein the syringe is slidably arranged with respect to the housing, spring capable of: pushing a needle from a covered position inside the housing into an advanced position, operating the syringe to supply a dose of medicament, and retracting the syringe with the needle into the covered position. Activating means is arranged to lock the spring in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring for injection. The spring is a single drive spring arranged for advancing the needle and for injecting the dose of medicament via a plunger. A damper is arranged with the plunger by a spline so as to cause rotation of either the plunger or the damper at least during part of a translation of the plunger in proximal direction.

Abstract: An injection device includes a syringe with a hollow needle and a stopper for sealing the syringe and displacing a medicament stored in the syringe. An arrangement for transferring a translation of a drive means to a plunger for pushing against the stopper includes a release latch pivoted at one end and connected to either the drive means or the plunger. The other end of the release latch engages the other one of the drive means or the plunger. The non-pivoted end of the release latch disengages by rotation upon contact between a ramp and another component when the stopper has displaced most of a predefined medicament dose. The release latch is long enough to provide a clearance between the plunger and the drive means when engaged to allow the plunger, stopper and needle to be retracted inside the syringe or a housing after disengaging the release latch.

Abstract: The invention relates to an auto-injector for administering a dose of a liquid medicament (M), comprising of an elongate housing arranged to contain a syringe with a hollow needle and a bung for sealing the syringe and displacing the medicament (M), the elongate housing having a distal end (D) and a proximal end (P) with an orifice intended to be applied against an injection site, wherein the syringe is slidably arranged with respect to the housing; spring means capable of, upon activation, pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P) as well as operating the syringe to supply the dose of medicament (M); and activating means arranged to lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection.

Abstract: A needle assembly (2) for a drug delivery device (1) comprises a needle seal (3), a needle retainer (4) and a needle (5). The needle retainer (4) secures the needle (5) against displacement with respect to said needle retainer (4) when a dose of drug is being delivered. The needle seal (3) is configured to push onto the needle retainer (4) after delivering the dose of the drug, thereby unlocking the needle (5) from the needle retainer (4).