Patents by Inventor Matthias Hoffmann

Matthias Hoffmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070270401
    Abstract: The present invention encompasses compounds of general formula (1) wherein R1 to R5 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.
    Type: Application
    Filed: April 5, 2007
    Publication date: November 22, 2007
    Inventors: Steffen STEURER, Bodo BETZEMEIER, Darryl MCCONNELL, Thomas GERSTBERGER, Matthias GRAUERT, Matthias HOFFMANN, Maria IMPAGNATIELLO, Lars van der VEEN, Ulrike WEYER-CZERNILOFSKY
  • Publication number: 20070259855
    Abstract: Disclosed are compounds of general formula (I), wherein the groups R1, R2, Ra and Rb have the meanings given in the claims and specification, the tautomers, racemates, enantiomers, diastereomers and the mixtures thereof, and optionally the pharmacologically acceptable acid addition salts, solvates and hydrates thereof, and processes for preparing these thiazolyl-dihydro-indazoles and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: March 23, 2007
    Publication date: November 8, 2007
    Inventors: Udo Maier, Matthias Grauert, Matthias Hoffmann, Christoph Hoenke, Anne Joergensen, Alexander Pautsch, Trixi Brandl, Steffen Breitfelder, Stefan Scheuerer, Klaus Erb, Michael Pieper, Ingo Pragst
  • Publication number: 20070244104
    Abstract: Disclosed are thiazolyl-dihydro-quinazolines of general formula (I) wherein the groups R1 to R4 have the meanings given in the claims and specification, the isomers thereof, and processes for preparing these compounds and their use as pharmaceutical compositions.
    Type: Application
    Filed: March 23, 2007
    Publication date: October 18, 2007
    Inventors: Trixi Brandl, Udo Maier, Matthias Hoffmann, Stefan Scheuerer, Anne Joergensen, Alexander Pautsch, Steffen Breitfelder, Matthias Grauert, Christoph Hoenke, Klaus Erb, Michael Pieper, Ingo Pragst
  • Publication number: 20070239371
    Abstract: A process for detecting the operating state of a pump of a pump system, involves the steps of: detecting at least one pressure nd/or flow profile P(t) in the pump system, computing of at least one characteristic value Kkal from the pressure and/or flow profile P(t), comparing the computed characteristic value Kkal with at least one defined characteristic value Kvor or with a range bordered by the characteristic value Kvor, the defined characteristic value Kvor or the characteristic value range corresponding to the operating state of the pump of interest, and outputting the operating state determined by the comparison. With the process, the operating states of pumps, pump systems and hydraulic systems is determined by the computed characteristic value Kkal characterizing the pulsation of the pressure and/or flow profile P(t) in a computation time interval ?tB, the pulsation quotient being computed as the computed characteristic value Kkal.
    Type: Application
    Filed: October 17, 2006
    Publication date: October 11, 2007
    Applicant: I F M ELECTRONIC GMBH
    Inventors: Lorenz HALBINGER, Matthias HOFFMANN, Joerg SCHUETZE, Daniel SPINNENHIRN, Alfred WAGNER
  • Publication number: 20070238746
    Abstract: Disclosed are compounds of general formula (I), wherein the groups A, R1, R2, Ra and Rb have the meanings given in the claims and specification, the tautomers, racemates, enantiomers, diastereomers and the mixtures thereof, and optionally the pharmacologically acceptable acid addition salts, solvates and hydrates thereof, and processes for preparing these thiazolyl-dihydro-quinazolines and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: March 23, 2007
    Publication date: October 11, 2007
    Inventors: Trixi Brandl, Udo Maier, Christoph Hoenke, Anne Joergensen, Alexander Pautsch, Steffen Breitfelder, Matthias Grauert, Matthias Hoffmann, Stefan Scheuerer, Klaus Erb, Michael Pieper, Ingo Pragst
  • Publication number: 20070238730
    Abstract: Disclosed are compounds of general formula (I), wherein the groups R1, R2, Ra and Rb have the meanings given in the claims and specification, the tautomers, racemates, enantiomers, diastereomers and the mixtures thereof, and optionally the pharmacologically acceptable acid addition salts, solvates and hydrates thereof, and processes for preparing these thiazolyl-dihydro-cyclopentapyrazoles and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: March 23, 2007
    Publication date: October 11, 2007
    Inventors: Steffen Breitfelder, Udo Maier, Christoph Hoenke, Anne Joergensen, Alexander Pautsch, Trixi Brandl, Matthias Grauert, Matthias Hoffmann, Stefan Scheuerer, Klaus Erb, Michael Pieper, Ingo Pragst
  • Publication number: 20070238718
    Abstract: The present invention relates to new thiazolyl-dihydro-indazoles of general formula (I) wherein the groups R1, R2 and R3 have the meanings given in the claims and specification, the tautomers, racemates, enantiomers, diastereomers and the mixtures thereof, and optionally the pharmacologically acceptable acid addition salts, solvates and hydrates thereof, and processes for preparing these thiazolyl-dihydro-indazoles and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: March 23, 2007
    Publication date: October 11, 2007
    Inventors: Matthias GRAUERT, Udo Maier, Matthias Hoffmann, Stefan Scheuerer, Anne Joergensen, Alexander Pautsch, Trixi Brandl, Christoph Hoenke, Steffen Breitfelder, Klaus Erb, Michael Pieper, Ingo Pragst
  • Patent number: 7279550
    Abstract: Presented are compounds represented by the following general formulas (I) and (II), for inhibiting cysteine protease legumain for modulating associated disease states in subjects
    Type: Grant
    Filed: July 23, 2002
    Date of Patent: October 9, 2007
    Assignee: Probiodrug AG
    Inventors: André Niestroj, Ulrich Heiser, Bernd Gerhartz, Matthias Hoffmann, Hans-Ulrich Demuth
  • Publication number: 20070207946
    Abstract: The present invention provides new uses of DPIV-inhibitors of the present invention, and their corresponding pharmaceutically acceptable acid addition salt forms, for lowering blood pressure levels.
    Type: Application
    Filed: May 3, 2007
    Publication date: September 6, 2007
    Inventors: Andrew Pospisilik, Hans Demuth, Konrad Glund, Matthias Hoffmann, Christopher McIntosh, Ray Pederson
  • Patent number: 7241769
    Abstract: The present invention comprises compounds of general formula (1) wherein A, X, Y, Z, Ra, Rb, Rc, R1, R2 and R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or anomalous cell proliferation, and the use thereof for preparing a pharmaceutical composition with the above-mentioned properties.
    Type: Grant
    Filed: May 18, 2005
    Date of Patent: July 10, 2007
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Heinz Stadtmueller, Harald Engelhardt, Ulrich Reiser, Stephan Karl Zahn, Rudolf Hauptmann, Martin Steegmaier, Ulrich Guertler, Matthias Hoffmann, Matthias Grauert
  • Patent number: 7241889
    Abstract: Disclosed are 6-formyl-tetrahydropteridines of the formula (I) wherein the groups R1 to R6 have the meanings given in the claims and specification, the isomers thereof, methods of preparing these 6-formyl-tetrahydropteridines and their use as medicaments.
    Type: Grant
    Filed: July 12, 2005
    Date of Patent: July 10, 2007
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Matthias Hoffmann, Matthias Grauert, Martin Steegmaier, Flavio Solca
  • Publication number: 20070102977
    Abstract: A motor vehicle seat back structure comprising a backrest support frame which consists of a surface turned towards the seat user's back, a lordosis support which is arranged on the front part of the backrest support frame for supporting the user's back and an adjusting device for vertically adjusting the lordosis support position with respect to the extension plane of said backrest support frame. The adjusting device comprises at least one adjusting element operably connected to the lordosis support and at least one sliding element which is displaceable with respect to said adjusting element and interacts therewith in such a way that when the sliding element moves, the adjusting element is displaced with a directional component perpendicularly to the displacement direction of the sliding element and performs an action on said lordosis support in the direction.
    Type: Application
    Filed: August 25, 2004
    Publication date: May 10, 2007
    Inventors: Markus Fischer, Matthias Hoffmann, Andrea Bauersachs, Michael Forkel, Jochen Hofmann, Alwin Macht, Georg Scheck
  • Publication number: 20070058669
    Abstract: An application unit and a modem unit for mobile communication are provided. The application unit comprises at least one application that exchanges data traffic with at least one protocol stack, wherein said at least one protocol stack transfers data between at least one of the applications and at least one physical interface. The modem unit comprises a broadcast facility for setting up a wireless connection, and at least one transmission protocol stack for transferring data traffic between the at least one physical interface and the broadcast facility. The modem unit collects flow control information about the status of the wireless connection. The flow control information are packed into an IP packet which is sent via the physical interface to the application unit. The application unit uses the received flow control information to optimize the quality of service.
    Type: Application
    Filed: July 30, 2004
    Publication date: March 15, 2007
    Applicant: FG Microtec GMBH
    Inventors: Matthias Hoffmann, Thomas Ketz, Vahid Mirbaha
  • Publication number: 20070043055
    Abstract: The present invention relates to the use of dihydropteridinones of formula 1 wherein the groups X, R1, R2, R3, R4, R5, R6 and R7 have the meanings given in the claims and specification, for the preparation of a medicament for the treatment of respiratory diseases.
    Type: Application
    Filed: July 18, 2006
    Publication date: February 22, 2007
    Inventors: Udo Maier, Frank Kalkbrenner, Frank Buettner, Steffen Breitfelder, Matthias Grauert, Matthias Hoffmann
  • Publication number: 20060287251
    Abstract: The present invention relates to method of treatment, in particular to a method for the treatment of diabetes mellitus, especially non-insulin dependent diabetes mellitus (NIDDM) or Type 2 diabetes and conditions associated with diabetes mellitus the predi,betic state and/or obesity and to compositions for use in s ch method.
    Type: Application
    Filed: September 2, 2004
    Publication date: December 21, 2006
    Inventors: Hans-Ulrich Demuth, Konrad Glund, Matthias Hoffmann
  • Publication number: 20060252701
    Abstract: The present invention discloses a method for therapeutically treating an animal, including a human, for psychosomatic, depressive and neuropsychiatric diseases, such as anxiety, depression, insomnia, schizophrenia, epilepsy, spasm and chronic pain. Administration of a suitable DP IV inhibitor causes the reduction of activity in the enzyme dipeptidyl peptidase (DP IV or CD 26) or of DP IV—like enzyme activity in the brain of mammals and leads as a causal consequence to a reduced degradation of the neuropeptide Y (NPY) and similar substrates by DP IV and DP IV-like enzymes. Such treatment will result in a reduction or delay in the decrease of the concentration of functionally active neuronal NPY (1-36).
    Type: Application
    Filed: April 4, 2006
    Publication date: November 9, 2006
    Inventors: Stephan von Hoersten, Ants Kask, Hans-Ulrich Demuth, Huu Nguyen, Susanne Kruber, Matthias Hoffmann
  • Patent number: 7132104
    Abstract: The present invention discloses a method for therapeutically treating an animal, including a human, for psychosomatic, depressive and neuropsychiatric diseases, such as anxiety, depression, insomnia, schizophrenia, epilepsy, spasm and chronic pain. Administration of a suitable DP IV inhibitor causes the reduction of activity in the enzyme dipeptidyl peptidase (DP IV or CD 26) or of DP IV-like enzyme activity in the brain of mammals and leads as a causal consequence to a reduced degradation of the neuropeptide Y (NPY) and similar substrates by DP IV and DP IV-like enzymes. Such treatment will result in a reduction or delay in the decrease of the concentration of functionally active neuronal NPY (1–36).
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: November 7, 2006
    Assignee: Probiodrug AG
    Inventors: Stephan von Horsten, Ants Kask, Hans-Ulrich Demuth, Huu Phuc Nguyen, Susanne Kruber, Matthias Hoffmann
  • Publication number: 20060213302
    Abstract: An adjustable mechanism for a motor vehicle is used to adjust an adjustable element in a motor vehicle, especially a seating part. Said mechanism comprises a spindle nut comprising an axis, said spindle nut co-operating with a thread spindle and comprising external toothing on the external surface thereof which is in contact with an additional drive element. The external toothing of the spindle nut is formed by recesses in the external surface of the spindle nut which are inwardly turned in a radial manner, the teeth depths thereof diminishing in the direction of at least one axial end of the spindle nut.
    Type: Application
    Filed: July 16, 2004
    Publication date: September 28, 2006
    Inventors: Matthias Hoffmann, Andrea Bauersachs, Andreas Prause
  • Publication number: 20060178315
    Abstract: Presented are compounds represented by the following general formulas (I) and (II), for inhibiting cysteine protease legumain for modulating associated disease states in subjects.
    Type: Application
    Filed: July 23, 2002
    Publication date: August 10, 2006
    Inventors: Andre Niestroj, Ulrich Heiser, Bernd Gerhartz, Matthias Hoffmann, Hans-Ulrich Demuth
  • Publication number: 20060106013
    Abstract: New compounds of formula 1 are provided which by virtue of their pharmaceutical activity as PI3-kinase modulators may be used in the therapeutic field for the treatment of inflammatory or allergic diseases. Examples of these include inflammatory and allergic respiratory complaints, inflammatory diseases of the gastrointestinal tract and motor apparatus, inflammatory and allergic skin diseases, inflammatory eye diseases, diseases of the nasal mucosa, inflammatory or allergic conditions involving autoimmune reactions or inflammations of the kidney.
    Type: Application
    Filed: October 5, 2005
    Publication date: May 18, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Steffen Breitfelder, Udo Maier, Trixi Brandl, Christoph Hoenke, Matthias Grauert, Alexander Pautsch, Matthias Hoffmann, Frank Kalkbrenner, Anne Joergensen, Gerhard Schaenzle, Stefan Peters, Frank Buettner, Eckhart Bauer