Patents by Inventor Matthias Hoffmann

Matthias Hoffmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiazolyl-dihydro-indazole
    Publication number: 20060100254
    Abstract: The present invention encompasses compounds of the general formula (1) in which R1 to R3 are defined as in Claim 1, which are suitable for treating diseases which are characterized by excessive or anomalous cell proliferation, and their use for producing a pharmaceutical having the abovementioned properties.
    Type: Application
    Filed: October 5, 2005
    Publication date: May 11, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Bodo Betzemeier, Trixi Brandl, Steffen Breitfelder, Ralph Brueckner, Thomas Gerstberger, Michael Gmachl, Matthias Grauert, Frank Hilberg, Christoph Hoenke, Matthias Hoffmann, Maria Impagnatiello, Dirk Kessler, Christian Klein, Bernd Krist, Udo Maier, Darryl McConnell, Charlotte Reither, Stefan Scheuerer, Andreas Schoop, Norbert Schweifer, Oliver Simon, Martin Steegmaier, Steffen Steurer, Irene Waizenegger, Ulrike Weyer-Czernilofsky, Andreas Zoephel
  • Carbamic acid esters with anticholinergic activity
    Patent number: 7041674
    Abstract: A compound of formula 1 wherein X?, A, R1, R2, R3, and R4 may have the meanings given in the claims and in the specification, processes for preparing them, their use in pharmaceutical compositions, and methods of treating patients using them.
    Type: Grant
    Filed: November 20, 2003
    Date of Patent: May 9, 2006
    Assignee: Boehringer Ingelhiem Pharma GmbH & Co. KG
    Inventors: Steffen Breitfelder, Matthias Hoffmann, Matthias Grauert, Michael P. Pieper, Georg Speck
  • Drive unit
    Patent number: 7038338
    Abstract: A driving unit especially adapted to adjusting devices for motor vehicles having an electric motor, a gear box and an electronic control device. At least one element of the electric motor, for example, at the driving shaft, the magnetic short-circuit or the motor side crankcase casing, additionally provides a gear box mechanical feature and/or a mechanical member, for example, a gear box side crankcase casing, provides an electric motor or electronic control device feature.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: May 2, 2006
    Assignee: Brose Fahrzeugteile GmbH & Co. KG
    Inventors: Helmut Sesselmann, Matthias Hoffmann, Markus Schultz
  • Drive unit
    Publication number: 20060082232
    Abstract: A driving unit especially adapted to adjusting devices for motor vehicles having an electric motor, a gear box and an electronic control device. At least one element of the electric motor, for example, at the driving shaft, the magnetic short-circuit or the motor side crankcase casing, additionally provides a gear box mechanical feature and/or a mechanical member, for example, a gear box side crankcase casing, provides an electric motor or electronic control device feature.
    Type: Application
    Filed: November 30, 2005
    Publication date: April 20, 2006
    Inventors: Helmut Sesselmann, Matthias Hoffmann, Markus Schultz
  • New dihydropteridione derivatives, process for their manufacture and their use as medicament
    Publication number: 20060052383
    Abstract: Disclosed are new dihydropteridinones of general formula (I) whereby the groups L, R1, R2, R3, R4 and R5 have the meanings given in the claims and specification, the isomers thereof, processes for preparing these dihydropteridinones and their use as pharmaceutical compositions.
    Type: Application
    Filed: August 24, 2005
    Publication date: March 9, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Matthias Grauert, Matthias Hoffmann, Martin Steegmaier, Christian Eickmeier, Gisela Schnapp, Norbert Redemann, Flavio Solca, Jens Quant
  • New dihydropteridione derivatives, process for their manufacture and their use as medicament
    Publication number: 20060046989
    Abstract: Disclosed are new dihydropteridinones of the formula (I) wherein the groups L, R1, R2, R3, R4 and R5 have the meanings provided herein, the isomers thereof, processes for preparing these dihydropteridinones and their use as pharmaceutical compositions.
    Type: Application
    Filed: August 24, 2005
    Publication date: March 2, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Matthias Grauert, Matthias Hoffmann, Martin Steegmaier, Flavio Solca, Jens Juergen Quant
  • New dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
    Publication number: 20060046990
    Abstract: Disclosed are new dihydropteridinones of general formula (I) wherein the groups R1 to R5, Ra to Rc, W, Q1 and Q2 have the meanings given in the claims and specification, the isomers thereof and the use thereof for preparing a pharmaceutical composition for the treatment of diseases characterised by excessive or abnormal cell proliferation.
    Type: Application
    Filed: August 25, 2005
    Publication date: March 2, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Heinz Stadtmueller, Harald Engelhardt, Andreas Schoop, Martin Steegmaier, Matthias Hoffmann, Matthias Grauert
  • Hydrates and polymorphs of 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
    Publication number: 20060035902
    Abstract: Disclosed are hydrates and polymorphs of 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, processes for preparing them and their use as pharmaceutical compositions.
    Type: Application
    Filed: August 4, 2005
    Publication date: February 16, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Guenter Linz, Peter Sieger, Gerd Kraemer, Rolf Herter, Matthias Hoffmann, Werner Rall, Rolf Schmid
  • Methods for treating diseases or conditions using dihydropteridinone compounds
    Publication number: 20060025411
    Abstract: Disclosed are new dihydropteridinones of general formula (I) wherein the groups L and R1-R5 have the meanings given in the claims and specification, the isomers thereof, intermediates and processes for preparing these dihydropteridinones and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: September 6, 2005
    Publication date: February 2, 2006
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Matthias Hoffmann, Matthias Grauert, Martin Steegmaier, Anke Baum, Jens Quant, Flavio Solca, Florian Colbatzky
  • New 6-formyl-tetrahydropteridines, process for their manufacture and use thereof as medicaments
    Publication number: 20060014751
    Abstract: Disclosed are 6-formyl-tetrahydropteridines of the formula (I) wherein the groups R1 to R6 have the meanings given in the claims and specification, the isomers thereof, methods of preparing these 6-formyl-tetrahydropteridines and their use as medicaments.
    Type: Application
    Filed: July 12, 2005
    Publication date: January 19, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Matthias Hoffmann, Matthias Grauert, Martin Steegmaier, Flavio Solca
  • New pyridodihydropyrazinones, process for their manufacture and use thereof as medicaments
    Publication number: 20060009457
    Abstract: Disclosed are pyridodihydropyrazinone compounds, processes for preparing them and their use as pharmaceutical compositions. The compounds according to the invention correspond to general formula (I), while the groups L, R1, R2, R3, R4 and R5 may have the meanings given in the claims and specification.
    Type: Application
    Filed: July 7, 2005
    Publication date: January 12, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Matthias Hoffmann, Matthias Grauert, Trixi Brandl, Martin Steegmaier, Rudolf Hauptmann
  • 2-Benzylaminodihydropteridinones, process for their manufacture and use thereof as medicaments
    Publication number: 20060004014
    Abstract: The present invention relates to new 2-benzylaminodihydropteridinones of general formula (I) wherein the groups R1 to R7, R10 and R11 have the meanings given in the claims and specification, the isomers thereof, methods of preparing these dihydropteridinones and their use as medicaments.
    Type: Application
    Filed: June 21, 2005
    Publication date: January 5, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Matthias Hoffmann, Matthias Grauert, Thorsten Lehmann-Lintz, Martin Steegmaier, Flavio Solca, Norbert Redemann
  • Pyrimidine as PLK inhibitors
    Publication number: 20050261295
    Abstract: The present invention comprises compounds of general formula (1) wherein A, X, Y, Z, Ra, Rb, Rc, R1, R2 and R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or anomalous cell proliferation, and the use thereof for preparing a pharmaceutical composition with the above-mentioned properties.
    Type: Application
    Filed: May 18, 2005
    Publication date: November 24, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Heinz Stadtmueller, Harald Engelhardt, Ulrich Reiser, Stephan Zahn, Rudolf Hauptmann, Martin Steegmaier, Ulrich Guertler, Matthias Hoffmann, Matthias Grauert
  • Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels
    Publication number: 20050107308
    Abstract: The present invention provides new uses of DPIV-inhibitors of the present invention, and their corresponding pharmaceutically acceptable acid addition salt forms, for lowering blood pressure levels.
    Type: Application
    Filed: October 21, 2004
    Publication date: May 19, 2005
    Inventors: Andrew Pospisilik, Hans-Ulrich Demuth, Kourad Glund, Matthias Hoffmann, Christopher McIntosh, Ray Pederson
  • Alkylphenyliminoimidazolidine derivatives for treating urinary incontinence
    Publication number: 20050085522
    Abstract: A compound of formula I or of tautomeric formula II wherein: R1 and R5 are each independently H, F, Cl, Br, CH2F, CHF2, CF3, Me, or OMe; R2 and R4 are each independently H, a branched C3-6-alkyl, F, Cl, Br, CH2F, CHF2, CF3 or Me, wherein at least one of the groups R2 or R4 is a branched C3-6-alkyl; and R3 is H, F, Cl, Br, CH2F, CHF2, CF3 or Me, or a pharmacologically acceptable salt thereof, pharmaceutical compositions containing these compounds, and their use in treating urinary incontinence or a bladder disease.
    Type: Application
    Filed: December 7, 2004
    Publication date: April 21, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Pascale Pouzet, Franz Esser, Matthias Hoffmann, Hisato Kitagawa, Kenji Sakai, Ikunobu Muramatsu
  • Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
    Patent number: 6861422
    Abstract: The present invention relates to new dihydropteridinones of general formula (I): wherein the groups L and R1-R5 have the meanings given in the claims and specification, the isomers thereof, processes for preparing these dihydropteridinones and the use thereof as pharmaceutical compositions.
    Type: Grant
    Filed: February 26, 2003
    Date of Patent: March 1, 2005
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Matthias Hoffmann, Matthias Grauert, Trixi Brandl, Steffen Breitfelder, Christian Eickmeier, Martin Steegmaier, Gisela Schnapp, Anke Baum, Jens Juergen Quant, Flavio Solca, Florian Colbatzky
  • Intermediate compounds for making dihydropteridinones useful as pharmaceutical compositions
    Publication number: 20050014761
    Abstract: Disclosed are new dihydropteridinones of general formula (I) wherein the groups L and R1-R5 have the meanings given in the claims and specification, the isomers thereof, intermediates and processes for preparing these dihydropteridinones and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: July 30, 2004
    Publication date: January 20, 2005
    Inventors: Matthias Hoffmann, Matthias Grauert, Trixi Brandl, Steffen Breitfelder, Christian Eickmeier, Martin Steegmaier, Gisela Schnapp, Anke Baum, Jens Quant, Flavio Solca, Florian Colbatzky
  • Methods of treating diseases or conditions using dihydropteridinone compounds
    Publication number: 20050014760
    Abstract: Disclosed are new dihydropteridinones of general formula (I) wherein the groups L and R1-R5 have the meanings given in the claims and specification, the isomers thereof, intermediates and processes for preparing these dihydropteridinones and the use thereof as pharmaceutical compositions.
    Type: Application
    Filed: July 30, 2004
    Publication date: January 20, 2005
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Matthias Hoffmann, Matthias Grauert, Trixi Brandl, Steffen Breitfelder, Christian Eickmeier, Martin Steegmaier, Gisela Schnapp, Anke Baum, Jens Quant, Flavio Solca, Florian Colbatzky
  • Glutaminyl based DP IV-inhibitors
    Publication number: 20040229848
    Abstract: The present invention relates dipeptidyl peptidase IV inhibition and, more particularly, relates to glutaminyl derivatives, wherein the glutamin residue is bound in a peptide manner to a moiety which imitates the amino acid residue prolin, especially to a nitrogen containing moiety, pharmaceutical compositions containing said compounds, and the use of said compounds in inhibiting dipeptidyl peptidase IV and dipeptidyl peptidase IV-like enzyme activity.
    Type: Application
    Filed: May 5, 2004
    Publication date: November 18, 2004
    Inventors: Hans-Ulrich Demuth, Matthias Hoffmann, Torsten Hoffmann, Andre J. Niestroj, Stephan Schilling, Ulrich Heiser
  • Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
    Patent number: 6806272
    Abstract: The present invention relates to new dihydropteridinones of the formula (I) wherein the groups X, R1, R2, R3, R4, R5 and R7 have the meanings given in the claims and the specification, the isomers thereof, processes and intermediates for preparing these dihydropteridinones as well as the use thereof as pharmaceutical compositions.
    Type: Grant
    Filed: August 23, 2002
    Date of Patent: October 19, 2004
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Eckhart Bauer, Steffen Breitfelder, Christian Eickmeier, Matthias Grauert, Matthias Hoffmann, Thorsten Lehmann-Lintz, Gerald Pohl, Jens Quant, Norbert Redemann, Gisela Schnapp, Martin Steegmaier