Abstract: The present invention relates to humanized antibodies or target-binding fragments or derivatives thereof retaining target binding capacities, which bind to human iRhom2 (FIG. 1).

Abstract: A system and method include reception of first code associated with an on-premise runtime environment and a first programming language, identification of tokens associated with the first programming language in the first code, removal of state dependencies from the first code based on the identified tokens and on transformation data mapping one or more of the identified tokens to a respective code transformation, to generate second code, execution of performance transformations on the second code to generate third code, execution of functional tests on the third code, in response to a determination that the functional tests were passed, separation of the third code into functional units to generate fourth code, application of a security function to one or more of the functional units to generate fifth code, and deployment of the fifth code to a cloud-based runtime environment.

Abstract: A method for carrying out an automatic inspection of a vehicle during a charging process at a charging station is disclosed, wherein a charging process of at least one battery of the vehicle is initiated and measurement data from surfaces of the at least one vehicle is determined by at least one sensor of the charging station, the determined measurement data being evaluated by a local and/or external controller with regard to damage and/or safety deficiencies, and an inspection report being provided in an automated manner during or after a completed charging process of the battery. Furthermore, a vehicle arrangement is disclosed.

Abstract: A machine tool device in one embodiment is configured to provide open-loop and/or closed-loop control of at least one machine tool function of a portable machine tool. The machine tool device includes at least one detection unit configured to detect at least one characteristic variable of the machine tool and/or of a processing tool arranged on the machine tool. The machine tool device further includes at least one brake unit, wherein at least one brake function of the brake unit is adapted at least partially automatically, and in particular dynamically, depending on the at least one detected characteristic variable.

Abstract: One embodiment relates to a multi-code system. The system includes a first subsystem and (at least) a second subsystem, each including an event bus terminal and a processor core. The system further includes an event bus comprising an event bus controller and a plurality of bus lines for connecting the first subsystem and the second subsystem with the event bus controller. The event bus controller includes an arbiter configured to arbitrate data transmission across the bus lines. The event bus terminal of each subsystem includes a first queue for outgoing data provided by the respective processor core and a frame encoder that is configured to read the outgoing data from the first queue and transmit it to the event bus controller.

Abstract: Disclosed is a method for initiating a charging process of an electrically drivable vehicle by an automated charging system, wherein the vehicle is parked on a charging space. The method includes determining a charging intention in an automated manner based on performing behavioral pattern recognition, authenticating the charging process and, after the authenticating, initiating the charging process by the automated charging system. Furthermore, a vehicle arrangement is disclosed.

Abstract: The present invention relates to a protein binder which, when bound to human iRhom2, binds at least within a region of Loop 1 thereof.

Abstract: A charging system for an electric vehicle is disclosed and may include a charging unit configured to electrically charge a traction battery of the electric vehicle and a cleaning system configured to clean an external surface of the electric vehicle. The cleaning system may comprise a cleaning unit, an arm coupled to the cleaning unit and movable relative to the cleaning unit, and a cleaning nozzle coupled to a free end of the arm. A method for operating a charging system for an electric vehicle is also disclosed.

Abstract: An H-bridge circuit for energizing an inductor. The H-bridge circuit has four switches. A freewheeling diode is connected in parallel with each switch.

Abstract: A charging system for charging of electrically powered vehicles is provided, which may comprise at least one charging unit, at least one solar module, and at least one wind generator, the wind generator configured to transform wind flow energy into electric energy and is directly or indirectly connected to the charging unit. The solar module may be situated above the wind generator in the vertical direction and the solar module and the wind generator may be arranged in or on a lifting unit, which may be movable with respect to a receiving unit in at least the vertical direction. A lift mechanism may be include, configured to move the lifting unit relative to the receiving unit. The disclosure furthermore relates to a charging station having a charging system.

Abstract: The present disclosure relates to a method for inhibiting or reducing TACE/ADAM17 activity in a human or animal subject. The method comprises administering to the human or animal subject an effective amount for reducing or inhibiting TACE/ADAM 17 activity of a protein binder which, when bound to human iRhom2, binds at least within a region of Loop 1 thereof, or of a nucleic acid that encodes for at least one chain of a protein binder which, when bound to human iRhom2, binds at least within a region of Loop 1 thereof.

Abstract: The present invention relates to humanized antibodies or target-binding fragments or derivatives thereof retaining target binding capacities, which bind to human iRhom2.

Abstract: A method for operating a charging station designed and provided for charging a traction battery of a motor vehicle with electric energy, wherein the charging station comprises a display device for displaying information and an operating device for receiving a manual input of a user. The display device and the operating device are relocated at least temporarily in relation to a housing of the charging station. A charging station for charging a traction battery of a motor vehicle with electric energy is also provided.

Abstract: A method for operating a charging station is provided and configured to charge a traction battery of a motor vehicle with electric energy, wherein the charging station may include a charging cable held by a charging arm of the charging station. Movement of the charging cable and/or a position of a user of the charging station making use of the charging cable may be detected by at least one sensor and the charging arm may be moved in a motorized manner in the direction of the movement of the charging cable and/or in the direction of the position of the user. The disclosure furthermore relates to a charging station for charging a traction battery of a motor vehicle with electric energy as well as a building arrangement having a charging station.

Abstract: A method for producing separated strip-like laminate components including an electronic component embedded between two laminate layers of a tape-like material. Individual components are placed at defined intervals by a placement device onto a tape-like, lower first laminate layer moved in a conveying direction by a transport device, after which a tape-like, upper second laminate layer moved in the conveying direction is applied to the first laminate layer with embedding of the components to form a laminate tape. The individual strip-like laminate components are cut from the laminate tape by a cutting device having a movable cutting blade, which laminate components are picked up by a gripper device and transported away. The front end of the laminate tape is gripped by the gripper device in the region of a component and moved synchronously with the clocked movement of the transport device by a predetermined distance through the cutting device and positioned relative to the cutting blade.

Abstract: The present invention is directed to methods of identifying and treating a human subject harboring a tumor or other disease comprising assessing HRG gene expression at a protein level in the human subject and administering a treatment comprising an anti-HER3 antibody to the human subject whose HRG gene expression at a protein level is assessed as high. The present invention is also directed to methods of identifying a human subject harboring a tumor or other disease comprising assessing HRG gene expression at a protein level in the human subject and withholding a treatment comprising an anti-HER3 antibody to the human subject whose HRG gene expression at a protein level is assessed as low.

Abstract: The present invention is directed to methods of identifying and treating a human subject harboring a tumor or other disease comprising assessing HRG gene expression at an mRNA level in the human subject and administering a treatment comprising an anti-HER3 antibody to the human subject whose HRG gene expression at an mRNA level is assessed as high. The present invention is also directed to methods of identifying a human subject harboring a tumor or other disease comprising assessing HRG gene expression at an mRNA level in the human subject and withholding a treatment comprising an anti-HER3 antibody to the human subject whose HRG gene expression at an mRNA level is assessed as low.

Abstract: The present invention is directed to methods of identifying and treating a human subject harboring a tumor or other disease comprising assessing HRG gene expression at a protein level in the human subject and administering a treatment comprising an anti-HER3 antibody to the human subject whose HRG gene expression at a protein level is assessed as high. The present invention is also directed to methods of identifying a human subject harboring a tumor or other disease comprising assessing HRG gene expression at a protein level in the human subject and withholding a treatment comprising an anti-HER3 antibody to the human subject whose HRG gene expression at a protein level is assessed as low.

Abstract: The present invention is directed to methods of identifying and treating a human subject harboring a tumor or other disease comprising assessing HRG gene expression at an mRNA level in the human subject and administering a treatment comprising an anti-HER3 antibody to the human subject whose HRG gene expression at an mRNA level is assessed as high. The present invention is also directed to methods of identifying a human subject harboring a tumor or other disease comprising assessing HRG gene expression at an mRNA level in the human subject and withholding a treatment comprising an anti-HER3 antibody to the human subject whose HRG gene expression at an mRNA level is assessed as low.