Abstract: In this application is described a novel, multiparameter analysis of TCR-coupled signaling and function in resting and activated naive and memory CD4 T cells, revealing a biochemical basis for immunological recall. Results reveal a novel biochemical signature imparted to memory CD4 T cells enabling efficacious responses through increased ZAP-70 expression and reduced accumulation of downstream signaling events.

Abstract: A method controls a functional element of an ear-level device of a type including a functional element, a memory, a microphone and a speaker, each coupled to a processor. Communication between the ear-level device and a companion device, such as a mobile phone, is established. A functional element for control is selected through the user interface of the companion device. A control instruction for controlling the selected functional element is chosen using the user interface and is transmitted from the companion device to the ear-level device to provide instruction to the ear-level device to control the selected functional element in the chosen way.

Abstract: A system, method and apparatus for policy-driven load balancing of MMEs and MME pools by migrating eNodeBs service responsibilities among MMEs and/or MME processing components or modules.

Abstract: A method for physical separation and purification of bioactive phenolics from fruits, berries and vegetables by subjecting a fruit, berry or vegetable extract solution having a Brix of from about 1 to about 4 to ultrafiltration using an about 2,000-6,000 Dalton cutoff ultrafiltration membrane under a pressure of about 30-120 psi, and a temperature of about 80-110° F. This is followed by subjecting the resulting retentate to diafiltration-ultrafiltration with the addition of water, using an about 2,000-6,000 Dalton cutoff ultrafiltration membrane under a pressure of about 30-120 psi, and a temperature of about 80-110° F., and recovering the diafiltered retentate or the bioactive phenolic containing solids thereof.

Abstract: This invention provides a method for contactless fingerprint detection and verification comprising illuminating a fingerprint and directing a reflected light through an imaging system using liquid crystal panels and birefringent elements to polarize the light. A plurality of polarized images are captured and used to calculate the depth of structural features on the fingertip. A means to generate a two-dimensional rolled equivalent image of the fingerprint is also provided which may then be used for verification and authentication. The invention also provides an imaging system for carrying out the method.

Abstract: A personalized hearing profile is generated for an ear-level device comprising a memory, microphone, speaker and processor. Communication is established between the ear-level device and a companion device, having a user interface. A frame of reference in the user interface is provided, where positions in the frame of reference are associated with sound profile data. A position on the frame of reference is determined in response to user interaction with the user interface, and certain sound profile data associated with the position. Certain data is transmitted to the ear level device. Sound can be generated through the speaker based upon the audio stream data to provide real-time feedback to the user. The determining and transmitting steps are repeated until detection of an end event.

Abstract: The disclosure relates to methods and reagents for analyzing samples for the presence of JC virus antibodies. Disclosed is a method that includes obtaining a biological sample from a subject (e.g., plasma, serum, blood, urine, or cerebrospinal fluid), contacting the sample with highly purified viral-like particles (HPVLPs) under conditions suitable for binding of a JCV antibody in the sample to an HPVLP, and detecting the level of JCV antibody binding in the sample to HPVLP. In one embodiment, determining the level of anti-JCV antibodies in the subject sample provides a method of identifying PML risk in a subject.

Abstract: Disclosed herein is a class of gas carburettor (9) for low calorific value gas for A/F ratio control to be used engines operating on producer gas with a load following capabilities. The gas carburettor has A/F ratio from 1.2:1 for producer gas to about 5:1 for biogas. The gas carburettor of the present invention has right A/F control at varying load conditions due to its optimized dimensions at the throat (7) and area ration control flapper (6) along with the zero pressure regulators. Additionally, using a by-pass facility starting the engine is established. By the use of a zero pressure regulator on the gas line, the gas pressure in the air and gas lines are maintained nearly the same downstream of the carburettor which helps in managing the appropriate air-to-fuel ratio based on the gas and air passage areas.

Abstract: In one embodiment, a system for designing and managing one or more social media campaigns is described. The system comprises at least one client capable of providing a user, access to a plurality of social media channels, a server communicatively coupled to the at least one client through a network, the server configured to extract user information from the at least one client, a demand side configured to be accessed by a marketer, a supply side configured to be accessed by the plurality of social media channels and a social media exchange platform configured to enable exchange of data between the demand side and the supply side. Method for designing and managing the social media campaigns is also disclosed.

Abstract: A fault monitoring system for an electrical substation includes one or more arrays of acoustic sensors placed around a substation boundary and configured to measure acoustic pressure waves. A processing circuitry in the fault monitoring system localizes and identifies faults in the substation and includes a sound source localization module to identify an area of a sound source based on the acoustic pressure waves. A beamforming module of processing circuitry provides enhanced acoustic pressure waves by eliminating background noise and interfering noise from the acoustic pressure waves and a component signature classification module in the processing circuitry compares enhanced acoustic pressure waves with component signatures to classify the acoustic pressure waves into various events to detect faults in the electrical substation.

Abstract: Disclosed herein are compounds of formula (I) wherein R1, R2, R3, R25a, R26a, X, and n are as defined in the specification. Pharmaceutical compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and pharmaceutical compositions are also described.

Abstract: Described herein are nucleic acid prodrugs and nucleic acid prodrugs comprising chiral phosphorous moieties. Also described herein are methods of making and using nucleic acid prodrugs and nucleic acid prodrugs comprising chiral phosphorous moieties.

Abstract: A device and method for detecting and locating defects in a cable are provided. The device and method may include using sensor feedback to determine that an insulation defect exists and to calculate the location of the insulation defect in a cable. The method may include performing principle component analysis to determine whether an insulation defect occurs and using extracted data to determine the location of the insulation defect.

Abstract: A system and device for detecting insulation defects in a cable are provided. The system and device include using signals received from sensors to detect a partial discharge caused by insulation defects in a cable. The system is passive, without signals being injected into system cables, and may use one or more sensors, data acquisition systems, gateway devices, and monitoring stations and is based on detecting partial discharge from insulation defects and reporting the detection when it occurs.

Abstract: A process for the selective recovery of Mo, V, Ni, Co and Al from spent hydroprocessing catalysts includes the steps of treating the spent catalysts to recovery metals, support as well as chemicals. The process steps include deoiling, decoking, washing, dissolving, complexing agent treatment, acid treatment and solvent extraction. This process uses limited steps than conventional processes by the use of ultrasonic agitation for metal extraction and the presence of a chelating agent particularly Ethylene Diamine Tetra-Acetic Acid (EDTA). The process also discloses the compete recovery of the extracting agent EDTA with high purity for reuse.

Abstract: A process for the recovery of high purity boehmite with controlled pore size from spent hydroprocessing catalyst includes the step of treating the spent hydroprocessing catalyst composition in order to get recovery of the aluminas after extracting the valuable metals. The process permits easy and resourceful recovery of high quality boehmite from waste catalyst, which can be further used as hydroprocessing catalyst carrier having a pore structure almost identical or better than that used in heavy oil hydroprocessing catalysts. Such catalyst carrier is required to have high pore volume, macro-porosity, high strength and optimum surface area for active metal dispersion. The treating steps include process steps such as decoking, roasting, leaching, dissolving, digestion, precipitation, washing, stripping, and the like. The recovery steps include digestion, hydrothermal treatment, flocculation or precipitation, filtration, drying, calcination and the like.

Abstract: A method of inducing mineralization in a bone cell is described. The method comprises contacting a bone cell with a composition comprising nanoparticles. The nanoparticles can be single-walled carbon nanotubes, hydroxyapatite nanoparticles, TiO2 nanoparticles or silver nanoparticles. The bone cell can be an osteoblast cell. A method for increasing bone mass, bone healing or bone formation is also described which comprises administering to a subject in need thereof an effective amount of a composition comprising nanoparticles. The subject can suffer from a bone disease such as osteoporosis. The subject can suffer from a bone fracture and the method can comprise contacting bone cells near the bone fracture site with the composition. The composition can further comprise a pharmaceutically acceptable carrier.

Abstract: A system for monitoring physiology, having: a RADAR transmitter and a RADAR receiver; a state estimation module configured to process a returned RADAR signal to detect a presence of motion and set a motion state upon said presence of motion, said state estimation module configured to detect a presence of one or more physiological parameters including heartbeat and respiration, and said state estimation module configured to assign a still state or a concern state based on said presence of physiological parameters; a rate estimation module configured to estimate one or more estimated physiological rates including an estimated respiration rate and an estimated heart rate; and an alerting module configured to provide an alert if an alert value exceeds an alert value threshold, wherein the alert value is derived from at least one of the motion state, concern state, still state and the estimated physiological rates.

Abstract: A method and apparatus for securing sensitive data from misappropriation by malicious software is provided. In one embodiment, the method for securing sensitive data from misappropriation by malicious software includes examining a history to identify potentially compromised sensitive data upon an occurrence of the malicious software and notifying a user regarding the potentially compromised sensitive data.

Abstract: The present invention relates to novel use of the extracts of Cassia tora plant species. The present invention particularly relates to novel use of the extracts of Cassia tora leaves, which show antianxiety activity. The present invention also relates to a process for the preparation of novel herbal extract of Cassia tora species with antianxiety activity and also to the use thereof for the treatment of anxiety.