Patents by Inventor Mei Zhang

Mei Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10678779
    Abstract: Provided are a computer program product, system, and method for generating sub-indexes from an index to compress the index. An index has levels of nodes for a composite key comprised of component keys. Each node includes at least one composite key value comprised of component key values. A plurality of sub-indexes is generated including one sub-index for each component key of the composite key. Nodes are generated in each sub-index corresponding to nodes in the index. In each node of the nodes of the sub-index, a component key value is generated, for the component key for which the sub-index was generated, from at least one composite key value in the corresponding node of the index. The sub-indexes are used to search for a record matching a search composite key value in the database using component key values of the search composite key value.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: June 9, 2020
    Assignee: International Business Machines Corporation
    Inventors: Xiaobo Wang, Shuo Li, Hong Mei Zhang, Shu Hua Liu
  • Patent number: 10662170
    Abstract: Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR40 receptor. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R5, R6, W, and A are defined herein.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: May 26, 2020
    Assignee: Janssen Pharmaceutica NV
    Inventors: Hui Huang, Gee-Hong Kuo, Mark R. Player, Shyh-Ming Yang, Yue-Mei Zhang
  • Publication number: 20200156027
    Abstract: A low-cost drug compounding system that can practically fit inside of a fume hood or the like is provided. The system can use a single pump operable in forward and reverse directions (or multiple pumps) to compound complex mixtures particularly including those requiring the creation of solutions from dry or powdered ingredients. A wireless link allows operation of the system remotely. In one embodiment, the system uses a disposable mixing tube set that can be discarded after mixing while still attached to the base ingredient containers used for the compounding thereby minimize the chance of personnel exposure.
    Type: Application
    Filed: January 23, 2020
    Publication date: May 21, 2020
    Inventors: Chao Young Lee, Mei Zhang
  • Patent number: 10640544
    Abstract: The present invention comprises conjugates comprising a monoclonal antibody conjugated to a cyclic PYY peptide. The invention also relates to pharmaceutical compositions and methods for use thereof. The novel conjugates are useful for preventing, treating or ameliorating diseases and disorders disclosed herein.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: May 5, 2020
    Assignee: JANSSEN PHARMACEUTICA NV
    Inventors: Mark Macielag, Raymond J Patch, Rui Zhang, Martin A Case, Shamina M Rangwala, James N Leonard, Raul C Camacho, Michael J Hunter, Katharine E. D'Aquino, Wilson Edwards, Ronald V Swanson, Wenying Jian, Yue-Mei Zhang, Mark Wall, Ellen Chi
  • Patent number: 10638406
    Abstract: The present invention relates to methods and apparatuses for providing selective network access, wherein a cell type indication is provided based on at least one of a preamble and a header portion of a broadcast signal. At the receiving end, it is checked based on at least one of the preamble and the header portion, whether broadcast signals are received from different first and second cell types. The first cell type is selected for network access, if both broadcast signals from the first and second cell types are received with sufficient strength.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: April 28, 2020
    Assignee: HMD Global Oy
    Inventors: Hai Jiang, Jian Feng Kang, Xiaoyi Wang, Chao Wei, Yi Wu, Dong Mei Zhang
  • Patent number: 10636146
    Abstract: A medical image processing method of determining a fractional flow reserve through a stenosis of a coronary artery from medical image data is disclosed. The medical image data comprises a set of images of a coronary region of a patient. The coronary region includes the stenosis. The method comprises: reconstructing a three dimensional model of a coronary artery tree of the patient from the medical image data; determining stenosis dimensions from the three dimensional model of the coronary artery tree of the patient; simulating blood flow in the three dimensional model of the coronary artery tree of the patient to determine modeled flow rates; using an analytical model depending on the stenosis dimensions to predict a modeled pressure drop over the stenosis from the modeled flow rates; and determining the fractional flow reserve through the stenosis from the modeled pressure drop.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: April 28, 2020
    Assignee: Singapore Health Services Pte Ltd
    Inventors: Liang Zhong, Jun Mei Zhang, Ru San Tan
  • Patent number: 10611830
    Abstract: The present invention provides an antibody or antibody fragment for specifically recognizing and binding to an ED-B domain of fibronectin. The antibody or antibody fragment can be widely used for in vitro detection and in vivo location of the ED-B protein domain, as well as targeted therapy of tumors.
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: April 7, 2020
    Assignee: HEFEI LIFEON PHARMACEUTICAL CO. LTD.
    Inventors: Junqiu Ji, Mei Zhang, Meihua Gao, Jun Chen
  • Publication number: 20200107109
    Abstract: Embodiments describe an acoustic shielding component including a stiffener formed of a rigid material providing structural integrity to the acoustic shielding component, a cosmetic mesh comprising a plurality of interlaced wires, and an acoustic mesh disposed between the stiffener and the cosmetic mesh. The stiffener includes first and second walls extending along a length of the stiffener and a plurality of ribs spaced apart from each other and extending between the first and second walls. The cosmetic mesh includes a mesh cover disposed over the stiffener and having an outer surface and an inner surface, and a mesh wall extending from an outer periphery of the inner surface of the mesh cover and defining a tab.
    Type: Application
    Filed: September 26, 2019
    Publication date: April 2, 2020
    Applicant: Apple Inc.
    Inventors: Benjamin A. Cousins, Esge Andersen, Mei Zhang, Brian R. Twehues, Ethan L. Huwe, Thanh P. Hua
  • Patent number: 10596532
    Abstract: A low-cost drug compounding system that can practically fit inside of a fume hood or the like is provided. The system can use a single pump operable in forward and reverse directions (or multiple pumps) to compound complex mixtures particularly including those requiring the creation of solutions from dry or powdered ingredients. A wireless link allows operation of the system remotely. In one embodiment, the system uses a disposable mixing tube set that can be discarded after mixing while still attached to the base ingredient containers used for the compounding thereby minimize the chance of personnel exposure.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: March 24, 2020
    Assignee: Zyno Medical, LLC
    Inventors: Chao Young Lee, Mei Zhang
  • Patent number: 10591334
    Abstract: A method of limiting a drive signal is provided. The method includes providing a drive signal for a meter assembly, wherein the meter assembly has a resonance frequency. The method also includes interrupting the drive signal after a first drive time-period, wherein the first drive time-period is based on an expected time for the drive signal to reach the resonance frequency.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: March 17, 2020
    Assignee: Micro Motion, Inc.
    Inventors: Fengchuan Gao, Kai Shen, Mei Zhang
  • Publication number: 20200045078
    Abstract: A method, an apparatus, a system, and a computer program product for handling security threats in a network data processing system. A computer system determines a connection type for a connection in response to detecting the connection between a target resource in the network data processing system and a requestor. The computer system redirects the connection to a virtual resource in place of the target resource when the connection type is a threat connection, wherein the requestor originating the connection to the target resource is unable to perceive a redirection of the connection to the virtual resource. The computer system records information in the connection redirected to the virtual resource to form recorded information. The computer system adjusts a security policy for handling connections in the network data processing system using the recorded information, wherein the security threats in the network data processing system are decreased using the security policy.
    Type: Application
    Filed: July 31, 2018
    Publication date: February 6, 2020
    Inventors: Sheng Yan Sun, Shuo Li, Xiaobo Wang, Hong Mei Zhang, Yu Wang
  • Patent number: 10555242
    Abstract: The present invention relates to methods and apparatuses for providing selective network access, wherein a cell type indication is provided based on at least one of a preamble and a header portion of a broadcast signal. At the receiving end, it is checked based on at least one of the preamble and the header portion, whether broadcast signals are received from different first and second cell types. The first cell type is selected for network access, if both broadcast signals from the first and second cell types are received with sufficient strength.
    Type: Grant
    Filed: June 6, 2008
    Date of Patent: February 4, 2020
    Assignee: HMD Global Oy
    Inventors: Hai Jiang, Jian Feng Kang, Xiao Yi Wang, Chao Wei, Yi Wu, Dong Mei Zhang
  • Publication number: 20200016331
    Abstract: A digital syringe is used with conventional polymer disposable syringe construction to be practical in the medical environment. Errors associated with the larger volumes of the syringes (which exacerbate minor errors in plunger position) and the flexibility and dimensional variations of the polymer plungers are accommodated by direct measurement of the syringe plunger position rather than indirect measurement of motor position and inference of syringe plunger position. This direct measurement eliminates mechanical tolerances (“stack up”) in the motor, gear train, and lead screw on plunger movement, an effect exacerbated by flexibility of the plunger and changes in syringe resistance and medicament viscosity, for example, with different medicaments or when the syringe is refrigerated. The digital syringe may be combined with the motor unit to provide additional versatility.
    Type: Application
    Filed: July 12, 2019
    Publication date: January 16, 2020
    Inventors: Chao Young Lee, Zhenhua Mao, Mei Zhang, Frederick Lee
  • Publication number: 20200004635
    Abstract: Systems, methods, and computer-readable media for fast convergence for virtual ethernet segments in EVPN and PBB-EVPN networks are disclosed. A first provider edge (PE) device can receive one or more advertising messages corresponding to one or more virtual ethernet segments, wherein each of the one or more advertising messages can include a port identifier. The first PE device maintains a table including the one or more virtual ethernet segments and the corresponding port identifier. The first PE device can receive a failure message from a second PE device that identifies a first port on the second PE device, and identifies, based on the table, at least one affected virtual ethernet segment that is associated with the first port. The first PE device can remove any routes that are associated with the at least one affected virtual ethernet segment and trigger mass designated-forwarding election for impacted virtual ethernet segments.
    Type: Application
    Filed: September 11, 2019
    Publication date: January 2, 2020
    Inventors: Ali Sajassi, Jose A. Liste, Patrice Brissette, Mei Zhang, Vi Vu
  • Patent number: 10507283
    Abstract: A pump system for pain management may receive input related to a patient's real-time pain to provide automatic adjustments of pain medication bolus delivery based on deduced patient pain. The pump may also collect pain management information during the delivery of pain medication to provide data for improved pain management protocols.
    Type: Grant
    Filed: May 26, 2015
    Date of Patent: December 17, 2019
    Assignee: Zyno Medical, LLC
    Inventors: Chaoyoung Lee, Mei Zhang
  • Publication number: 20190367577
    Abstract: The present invention relates to a monoclonal antibody platform designed to be coupled to therapeutic peptides to increase the half-life of the therapeutic peptide in a subject. The invention also relates to pharmaceutical compositions and methods for use thereof.
    Type: Application
    Filed: August 16, 2019
    Publication date: December 5, 2019
    Inventors: Mark MACIELAG, Raymond J. PATCH, Rui ZHANG, Martin A. CASE, Shamina M. RANGWALA, James N. LEONARD, Raul C. CAMACHO, Michael J. HUNTER, Katharine E. D'AQUINO, Wilson EDWARDS, Ronald V. SWANSON, Wenying JIAN, Yue-Mei ZHANG, Mark J. WALL, Ellen CHI
  • Publication number: 20190356599
    Abstract: In one embodiment, a method according to the present disclosure includes receiving a topology change message at a core edge node and performing a network address information removal operation. The core edge node participates in network communications with one or more access network nodes of an access network using an access network protocol. The topology change message indicates that a topology change has occurred in the access network, and the topology change message conforms to the access network protocol. The network address information removal operation removes network address information stored by the core edge node, and the network address information is used by the core edge node in participating in the network communications.
    Type: Application
    Filed: May 15, 2018
    Publication date: November 21, 2019
    Inventors: Patrice Brissette, Ali Sajassi, Mei Zhang, Luc Andre Burdet
  • Publication number: 20190345214
    Abstract: The present invention comprises compounds of Formula I. wherein: Z4, Z7, Z9, Z11, Z22, Z23, Z26, Z30, Z34, Z35, p, m, n, q, and BRIDGE are defined in the specification. The invention also relates to pharmaceutical compositions and methods for use thereof. The novel compounds are useful for preventing, treating or ameliorating diseases and disorders, such as obesity, type 2 diabetes, the metabolic syndrome, insulin resistance, and dyslipidemia, among others.
    Type: Application
    Filed: October 26, 2017
    Publication date: November 14, 2019
    Inventors: Mark MACIELAG, Raymond J. PATCH, Rui ZHANG, Martin A. CASE, Mark J. WALL, Yue-Mei ZHANG
  • Publication number: 20190330296
    Abstract: The present invention comprises conjugates comprising a glucagon-like peptide 1 (GLP-1) fusion peptide coupled to a cyclic PYY peptide. The invention also relates to pharmaceutical compositions and methods for use thereof. The novel conjugates are useful for preventing, treating or ameliorating diseases and disorders disclosed herein.
    Type: Application
    Filed: April 24, 2019
    Publication date: October 31, 2019
    Inventors: Yue-Mei ZHANG, Raul C. CAMACHO, Martin A. CASE, Ellen CHI, Suzanne EDAVETTAL, Wilson EDWARDS, Lisa NORQUAY, Mark J. WALL, Rui ZHANG, Songmao ZHENG
  • Publication number: 20190318496
    Abstract: According to one or more embodiments, a method, a computer program product, and a computer system for preventing intrusion during video recording or streaming are provided. According to the method, at first, a camera of a device may capture a scene into a video, then the device may store frame-series images of the video into a cache. The device may then detect whether there is at least one intruder in the scene, and then in response to the at least one intruder being detected in the scene, the device may eliminate the at least one intruder from the cached frame-series images.
    Type: Application
    Filed: April 11, 2018
    Publication date: October 17, 2019
    Inventors: Fang Lu, Dan Zhang, Jing Ran Yang, Ye Xu, Ke Huan Yin, Tai Mei Zhang