Patents by Inventor Mei Zhang

Mei Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • One class of pyrazolone compounds and use thereof
    Patent number: 10196389
    Abstract: Provided are a class of pyrazolone compounds and a use thereof. In particular, a compound represented by formula I is provided, wherein the definition of each variable group is as described in the description. The compounds of formula (I) have a direct AMPK-activating activity and can significantly promote the phosphorylation of AMPK and ACC of L6 myocytes and HepG2 cells in a dose-dependent manner.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: February 5, 2019
    Assignee: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
    Inventors: Fajun Nan, Jia Li, Jingya Li, Mei Zhang, Dakai Chen, Lina Zhang, Runtao Zhang, Zhifu Xie
  • LIMITING A DRIVE SIGNAL
    Publication number: 20190033112
    Abstract: A method of limiting a drive signal is provided. The method includes providing a drive signal for a meter assembly, wherein the meter assembly has a resonance frequency. The method also includes interrupting the drive signal after a first drive time-period, wherein the first drive time-period is based on an expected time for the drive signal to reach the resonance frequency.
    Type: Application
    Filed: February 26, 2016
    Publication date: January 31, 2019
    Applicant: Micro Motion, Inc.
    Inventors: Fengchuan GAO, Kai Shen, Mei Zhang
  • BENZIMIDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS
    Publication number: 20190031618
    Abstract: The present invention is directed to benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions mediated by the CB-1 receptor, more particularly, use in the treatment of disorders and conditions responsive to inverse agonism of the CB-1 receptor. More particularly, the compounds of the present invention are useful in the treatment of metabolic disorders.
    Type: Application
    Filed: October 3, 2018
    Publication date: January 31, 2019
    Applicant: Janssen Pharmaceutica NV
    Inventors: Mark J. Macielag, Rui Zhang, Yue-Mei Zhang, Bin Zhu, Michael H. Parker, Donald W. Ludovici, Daniel J. Parks, Bart L. DeCorte, Michael N. Greco
  • Therapy-specific medical pump
    Patent number: 10188809
    Abstract: A medical pump provides programming to assist a patient in complying with treatment schedules involving varying dosages of medicament(s). The pump includes stored treatment schedules and protocols that describe control of flow control device(s) for delivering different medicines according to the protocols and which may provide reminders and instructions to the patient.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: January 29, 2019
    Assignee: Zyno Medical, LLC
    Inventors: Chaoyoung Lee, Mei Zhang
  • FABRICATION AND APPLICATION OF NANOFIBER RIBBONS AND SHEETS AND TWISTED AND NON-TWISTED NANOFIBER YARNS
    Publication number: 20190002283
    Abstract: A nanofiber forest on a substrate can be patterned to produce a patterned assembly of nanofibers that can be drawn to form nanofiber sheets, ribbons, or yarns.
    Type: Application
    Filed: January 9, 2018
    Publication date: January 3, 2019
    Applicant: Board of Regents, The University of Texas System
    Inventors: Mei Zhang, Shaoli Fang, Ray H. Baughman, Anvar A. Zakhidov, Kenneth Ross Atkinson, Ali E. Aliev, Sergey Li, Chris Williams
  • Drug Design Method, Obtained Drug and Application Thereof
    Publication number: 20190002516
    Abstract: Provided is a drug system design method, comprising selecting a target moiety specifically binding to a target of interest, and connecting the target moiety to a biologically active moiety and/or connecting the target moiety to a biologically inert moiety. Also provided are a test kit, a drug kit or a pharmaceutical composition including a biologically inert drug comprising the target moiety and the biologically inert moiety and a biologically active drug comprising the target moiety and the biologically active moiety, wherein the biological inert drug and the biologically active drug target a same target. Also provided is a method for using the drugs or the pharmaceutical composition to treat diseases such as those related to ED-B.
    Type: Application
    Filed: December 21, 2016
    Publication date: January 3, 2019
    Inventors: Mei Zhang, Junqiu Ji, Meihua Gao, Jun Chen
  • Camera module with integrated chip-on-board image sensing chip
    Patent number: 10171715
    Abstract: A camera module includes a circuit board, a camera device and an image processing chip. An image sensation chip of the camera device is directly integrated with the circuit board by means of chip-on-board (COB) manufacturing process to minify the total volume of the camera module, whereby the camera module can be disposed in a narrow space.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: January 1, 2019
    Assignee: ASIA VITAL COMPONENTS CO., LTD.
    Inventors: Wei-Chuan Wang, Xin-Lian Cheng, Ting-Yu Lin, Chun-Mei Zhang, Chin-Lian Yeh
  • Electronic device for checking fastening state of screws
    Patent number: 10166661
    Abstract: An electronic device for checking a fastening state of screws includes a receiving member, a cover, an electric screwdriver, a processor, and a warning unit. The receiving member receives a mountable device. The cover includes a number of screw guiding members, the screw guiding members guides the screws into screw holes on the mountable device. The electric screwdriver fastens the screws into the screw holes on the mountable device. The processor predefines an order of the electric screwdriver fastening the screws in response to operations of an operator; in a process of the electric screwdriver fastening the screws into the screw holes on the mountable device received in the receiving member, checks whether the fastening order is the same as the predefined order; and when the fastening order is not the same as the predefined order, controls the warning unit to output a warning message.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: January 1, 2019
    Assignees: HONGFUJIN PRECISION ELECTRONICS (ZHENGZHOU) CO., LTD., HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Guo-Liang Huang, Rong-Yun Sun, Bao-Rui Han, Yan-Mei Zhang, Xiao-Kui Xu
  • PBB-EVPN customer MAC synchronization among all-active multi-homing PEs
    Patent number: 10158567
    Abstract: A method for assisting media access control (MAC) address learning is disclosed. The method includes receiving, at a first provider edge (PE) device, a data packet from a core network, the data packet identifying an Ethernet Segment (ES) from which the data packet originated and identifying a first MAC address as the destination MAC address; determining, at the first PE device, whether the first PE device has an Ethernet connection in the ES identified by the data packet and whether the first PE device has learned the first MAC address; and, upon positive determination, sending an announcement message to the core network, the announcement message identifying the first MAC address.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: December 18, 2018
    Assignee: Cisco Technology, Inc.
    Inventors: Mei Zhang, Yushun Zhang, Ali Sajassi, Thomas Eric Ryle, Richard Thomas Wood, Nathan Allen Mitchell
  • Novel Double-liner Electric Cooker
    Publication number: 20180352992
    Abstract: Disclosed is a double-liner electric cooker, comprising a cooker body, liners and cooker covers, wherein two liners and two cooker covers are provided, the cooker body is provided with a first inner cavity, two first inner cavities are mutually separated via a thermal insulation plate, and the two first inner cavities are both provided with cavity openings for the liners to be placed therein; the rear ends of the two cooker covers are respectively hinged to the edges of the cavity openings via hinge shafts, and the axial directions of the two hinge shafts intersect. The electric cooker is convenient to open, and on the basis that the sealing members are convenient to assemble and disassemble, the cooker cover can still maintain good sealing effects.
    Type: Application
    Filed: April 30, 2015
    Publication date: December 13, 2018
    Applicant: Stent (Guangzhou) Industrial Co. Ltd.
    Inventor: Mei Zhang
  • USE OF ED-B PROTEIN IN DIAGNOSIS OF TISSUE HYPERPLASIA
    Publication number: 20180340936
    Abstract: Disclosed are a use of an ED-B protein as a tissue hyperplasia (such as tumor) marker, a method for detecting the ED-B protein, and a diagnostic kit comprising the ED-B protein. The kit of the present invention comprises a genetically-engineered antibody against the tumor marker ED-B.
    Type: Application
    Filed: November 16, 2015
    Publication date: November 29, 2018
    Applicant: HEFEI LIFEON PHARMACEUTICAL CO. LTD.
    Inventors: Junqiu Ji, Mei Zhang, Meihua Gao, Jun Chen
  • Modular medical pump system
    Patent number: 10130754
    Abstract: A modular medical pump system provides separate pump units that may be pre-associated with flexible tubes. Multiple pump units may be installed in a controller that coordinates operation of the pump units for delivery of multiple medicaments to a patient. The pump units may carry drug information and the controller may hold patient information allowing drug delivery and interaction to be assessed by the controller.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: November 20, 2018
    Assignee: Zyno Medical, LLC
    Inventors: Chao Young Lee, Mei Zhang
  • Substituted benzothiophenyl derivatives as GPR40 agonists for the treatment of type II diabetes
    Patent number: 10131648
    Abstract: Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR40 receptor. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R5, R6, W, and A are defined herein.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: November 20, 2018
    Assignee: Janssen Pharmaceutica NV
    Inventors: Hui Huang, Gee-Hong Kuo, Mark R. Player, Shyh-Ming Yang, Yue-Mei Zhang
  • Capacitive touch sensor
    Patent number: 10128840
    Abstract: A capacitive touch sensor (100) is provided. The capacitive touch sensor (100) includes an electrode (110) disposed between a plate (120) and a spring (130) wherein the spring (130) presses the electrode (110) towards the plate (120) in a direction that is substantially parallel to a longitudinal length (L) of the spring (130) and the electrode (110) has a flat sensing surface (112) parallel with the plate (120).
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: November 13, 2018
    Assignee: Micro Motion, Inc.
    Inventors: Mei Zhang, Heng Zhao, Yingxue Xu, Kai Shen, Chengjun Liu, Meng Ge
  • Benzimidazole derivatives useful as CB-1 inverse agonists
    Patent number: 10118900
    Abstract: The present invention is directed to benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions mediated by the CB-1 receptor; more particularly, use in the treatment of disorders and conditions responsive to inverse agonism of the CB-1 receptor. More particularly, the compounds of the present invention are useful in the treatment of metabolic disorders.
    Type: Grant
    Filed: August 23, 2016
    Date of Patent: November 6, 2018
    Assignee: Janssen Pharmaceutica NV
    Inventors: Mark J. Macielag, Rui Zhang, Yue-Mei Zhang, Bin Zhu, Michael H. Parker, Donald W. Ludovici, Daniel J. Parks, Bart L. DeCorte, Michael N. Greco
  • Medical pump with operator-authorization awareness
    Patent number: 10074446
    Abstract: A medical pump for delivering medicament through an IV line to a patient may provide for awareness of the operator and operator authority limiting access by any individual to particular tasks of procedure review, pump programming, pump loading, patient set up, pump operation, and the like associated with the treatment provided by the medical pump. Identifying the operator allows the assignment of particular authority levels to the operators to ensure proper operation of the medical pump, and/or proper operators have made the necessary review to perform the necessary set up of the medical pump facilitating collaborative healthcare delivery. A record of operator intervention and authority levels may be logged to permit an automatic checklist process by the medical pump. Authentication process and pump operation parameters can be communicated through Near Field Communication (NFC).
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: September 11, 2018
    Assignee: Zyno Medical, LLC
    Inventors: Chaoyoung Lee, Todd Sjolander, Mei Zhang
  • Spare component ownership planning system and method
    Patent number: 10062053
    Abstract: A system and method according to which a recommended quantity of spare engine components is generated. In several exemplary embodiments, the components support aircraft maintenance and flight operations and are designed to be repaired periodically. In an exemplary embodiment, the recommended quantity is a number of available spare engine components that supports the aircraft maintenance operations but avoids excess spare engine components in inventory.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: August 28, 2018
    Assignee: AMERICAN AIRLINES, INC.
    Inventors: Steven James Oakley, Jose Antonio Ramirez-Hernandez, Mei Zhang, Alejandro Edgardo Scalise, Louis Matthew Pfeifer
  • METHOD OF GENERATING TUMOR-SPECIFIC T CELLS
    Publication number: 20180228844
    Abstract: A method of treating cancer in a subject includes contacting an enriched population of T-cells obtained from cancer or tumor draining lymph nodes ex-vivo with: an anti-CD3 antibody, an anti-CD28 antibody, and/or functional fragments thereof, and optionally a VEGF inhibitor and/or an IL-2 receptor agonist, at amounts effective to activate and expand the T-cells and administering the activated and expanded T-cells to the subject.
    Type: Application
    Filed: April 16, 2018
    Publication date: August 16, 2018
    Inventors: Julian Kim, Kevin Choong, Hallie Graor, Mei Zhang, John Ammori, Anthony Visioni
  • CAMERA MODULE
    Publication number: 20180213129
    Abstract: A camera module includes a circuit board, a camera device and an image processing chip. An image sensation chip of the camera device is directly integrated with the circuit board by means of chip-on-board (COB) manufacturing process to minify the total volume of the camera module, whereby the camera module can be disposed in a narrow space.
    Type: Application
    Filed: January 26, 2017
    Publication date: July 26, 2018
    Inventors: Wei-Chuan Wang, Xin-Lian Cheng, Ting-Yu Lin, Chun-Mei Zhang, Chin-Lian Yeh
  • Ethernet segment aware MAC address learning
    Patent number: 10033636
    Abstract: A computer-implemented method for assisting Ethernet Segment (ES)-aware media access control (MAC) address learning is disclosed. The method includes receiving, at a provider edge (PE) device, a data packet from a core network, the data packet identifying an ES from which the data packet originated and identifying a MAC address as a source MAC address; determining whether the PE device has an Ethernet connection in the ES identified by the data packet; and, upon positive determination, associating the MAC address identified as the source MAC address of the data packet to a bridge port, at the PE device, of the Ethernet connection in the ES identified by the data packet.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: July 24, 2018
    Assignee: Cisco Technology, Inc.
    Inventors: Mei Zhang, Yushun Zhang, Ali Sajassi, Thomas Eric Ryle, Richard Thomas Wood, Nathan Allen Mitchell