Patents by Inventor Mei Zhang

Mei Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11780900
    Abstract: The present invention comprises conjugates comprising a glucagon-like peptide 1 (GLP-1) fusion peptide coupled to a cyclic PYY peptide. The invention also relates to pharmaceutical compositions and methods for use thereof. The novel conjugates are useful for preventing, treating or ameliorating diseases and disorders disclosed herein.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: October 10, 2023
    Assignee: Janssen Sciences Ireland Unlimited Company
    Inventors: Yue-Mei Zhang, Raul Camacho, Martin A. Case, Ellen Chi, Suzanne Edavettal, Wilson Edwards, Lisa Norquay, Mark J. Wall, Rui Zhang, Songmao Zheng
  • Publication number: 20230315710
    Abstract: A computer-implemented method includes: collecting, by a computing device, database activities and database structure information of a database; identifying, by the computing device, related columns in the database; determining, by the computing device, one or more data types for column transference of the identified related columns; generating, by the computing device, a super union column based on the column transference and the identified related columns; and updating, by the computing device, the database with the super union column.
    Type: Application
    Filed: March 30, 2022
    Publication date: October 5, 2023
    Inventors: Sheng Yan SUN, Hong Mei ZHANG, Peng Hui JIANG, Meng WAN
  • Publication number: 20230315725
    Abstract: An embodiment includes generating a partition schema for a distributed database based on historical usage data indicative of usage of the distributed database, where the generating of the partition schema comprises determining a partition range of a partition of the partition schema. The embodiment also includes generating a node identifier for the partition using a hash function and a first weight value assigned to the partition. The embodiment also includes monitoring performance data indicative of a performance of the distributed database, the monitoring comprising detecting a failure of the performance to satisfy a performance threshold. The embodiment also includes initiating, responsive to detecting the failure, a redistribution procedure by changing the node identifier of the partition by replacing the first weight value with a second weight value.
    Type: Application
    Filed: March 31, 2022
    Publication date: October 5, 2023
    Applicant: International Business Machines Corporation
    Inventors: Hong Mei Zhang, Sheng Yan Sun, Meng Wan, Peng Hui Jiang
  • Patent number: 11775517
    Abstract: Query content-based data generation includes obtaining a query having an outer query and one or more subqueries, converting predicates of a subquery to be predicates of the outer query, and thereby obtain a transformed query, generate from the transformed query a query block having a list of predicate(s) selected from the transformed query, obtaining column information based on the list of predicate(s) and using the column information to select data for a dataset such that data records from the dataset are produced as results to executing the obtained query against the dataset.
    Type: Grant
    Filed: March 18, 2022
    Date of Patent: October 3, 2023
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Shuo Li, Xiaobo Wang, ShengYan Sun, Hong Mei Zhang
  • Publication number: 20230306012
    Abstract: Disclosed are techniques for relational database locks based on columns. Database transactions may be targeted to specific columns of one or more records, instead of the entire row for those records, using primary keys. Column locks on specific keys are stored separately than column locks on ranges of keys, which are both checked when requesting a new column lock for either a single key or a range of keys. When a threshold number of columns for a given record, or range of records/keys, have been locked, the column locks for that record, or range of records, can be combined into a single row level lock to reduce resource costs for maintaining multiple concurrent locks.
    Type: Application
    Filed: March 23, 2022
    Publication date: September 28, 2023
    Inventors: Shuo Li, Xiaobo Wang, Hong Mei Zhang, Sheng Yan Sun
  • Patent number: 11767354
    Abstract: The present invention comprises conjugates comprising a monoclonal antibody conjugated to a cyclic PYY peptide. The invention also relates to pharmaceutical compositions and methods for use thereof. The novel conjugates are useful for preventing, treating or ameliorating diseases and disorders disclosed herein.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: September 26, 2023
    Assignee: Janssen Pharmaceutica NV
    Inventors: Mark Macielag, Raymond J. Patch, Rui Zhang, Martin A. Case, Shamina M. Rangwala, James N. Leonard, Raul C. Camacho, Michael J. Hunter, Katharine E. D'Aquino, Wilson Edwards, Ronald V. Swanson, Wenying Jian, Yue-Mei Zhang, Mark J. Wall, Ellen Chi
  • Patent number: 11762578
    Abstract: A computer-implemented method that includes managing a buffer pool of pages into a ring sub-chain comprising pages linked in a ring, and a linear sub-chain comprising pages linked in a line from a header, and moving a page between the linear sub-chain and the ring sub-chain based on a moving schema evaluating a chain management characteristic.
    Type: Grant
    Filed: September 29, 2020
    Date of Patent: September 19, 2023
    Assignee: International Business Machines Corporation
    Inventors: Shuo Li, Xiaobo Wang, Sheng Yan Sun, Hong Mei Zhang
  • Publication number: 20230289342
    Abstract: In a computer-implemented method for improving performance of a database, a processor receives batch jobs for a relational database. The batch jobs may include a first member with a first buffer pool, and a second member with a second buffer pool. The processor may also identify a first actual object and an isolation level for the batch jobs, generate related queries based on the first actual object and the isolation level, calculate a cost for the first member and the second member to run the batch jobs based on the related queries, and assign the batch jobs to the first member based on a lower calculated cost.
    Type: Application
    Filed: March 9, 2022
    Publication date: September 14, 2023
    Inventors: Sheng Yan Sun, Hong Mei Zhang, Meng Wan, Peng Hui Jiang
  • Publication number: 20230274810
    Abstract: Systems and methods are disclosed for a numeric waiting bin for prescription fulfillment. A computing system may be used to receive bin configuration values corresponding to a plurality of physical bins for prescription storage. The bin configuration values may be used to assign serial identifiers to the plurality of bins. Prescriptions may be selectively assigned a bin serial identifier using a plurality of rules and the bin serial number may be used to locate the prescription when the prescription is requested, such as during pickup.
    Type: Application
    Filed: May 4, 2023
    Publication date: August 31, 2023
    Inventors: Nathaniel D. Gilman, Christopher J. Goody, Kyle J. McGrath, Jeffrey Swindling, Jared P. Tancrelle, Li Mei Zhang
  • Publication number: 20230271917
    Abstract: In some embodiments, the present disclosure provides amino acid compounds that are useful for producing products such as peptides. In some embodiments, the present disclosure provides peptides comprising residues of provided amino acids.
    Type: Application
    Filed: July 22, 2021
    Publication date: August 31, 2023
    Inventors: Ivan Tucker Jewett, Lorenzo Josue Alfaro-Lopez, Yue-Mei Zhang, Brian Halbert White
  • Publication number: 20230273907
    Abstract: A method of managing time series data workload requests includes receiving a workload job request from a user in a multi-tenant network, the request specifying a plurality of workloads, each workload including time series data configured to be stored in a time series database (TSDB), inputting workload information to a workload model that is specific to the user, and classifying each workload according to the workload model, the workload model configured to classify each workload based on a plurality of parameters, the plurality of parameters including at least a workload type and an amount of storage associated with each workload. The method also includes assigning each workload of the plurality of workloads into one or more workload groups based on the classifying, and executing each workload according to the workload type and the storage size.
    Type: Application
    Filed: January 28, 2022
    Publication date: August 31, 2023
    Inventors: Peng Hui Jiang, Sheng Yan Sun, Meng Wan, Hong Mei Zhang
  • Publication number: 20230269514
    Abstract: An earphone comprising: a device housing that defines an interior cavity within the device housing; an acoustic port formed through a wall of the device housing; an audio driver disposed within the device housing and aligned to emit sound through the acoustic port; a user input region disposed along an exterior surface of the device housing; a flex circuit disposed within the interior cavity, the flex circuit including a first portion bonded at a first location to an inner surface of the device housing directly beneath the user-input region, a second portion bonded at a second location to an inner surface of the device housing spaced apart from the first location, and a third portion extending between the first and second portions; a force pixel disposed within the interior cavity and mounted to the first portion of the flex circuit below the user input region; a plurality of touch pixels disposed within the interior cavity between the force pixel and the user input region; sensor control circuitry disposed w
    Type: Application
    Filed: August 24, 2022
    Publication date: August 24, 2023
    Applicant: APPLE INC.
    Inventors: Benjamin A. Cousins, Travis Owens, Karan Jain, Lee M. Panecki, Mei Zhang, Julia Canning
  • Patent number: 11734277
    Abstract: An approach is provided for optimizing a database buffer pool. Based on statistics about read and write operations in a range of pages, the range of pages is determined to be a candidate for a hot read range for which locks and latches are avoided in processing operations in the hot read range. Using an on-time trigger or pre-trigger process, the hot read range is created from the range of pages by marking start and end points in the range of pages. Write operation(s) are determined to be included in the hot read range by marking an object control block. The write operation(s) are added to a write pending list. The read operations in the hot read range are performed without a latch or lock. The write operation(s) are merged from the write pending list to the range of pages and the write operation(s) are performed.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: August 22, 2023
    Assignee: International Business Machines Corporation
    Inventors: Shuo Li, Xiaobo Wang, Hong Mei Zhang, Sheng Yan Sun
  • Patent number: 11732019
    Abstract: The present invention comprises compounds of Formula I. wherein: Z4, Z7, Z9, Z11, Z22, Z23, Z26, Z30, Z34, Z35, p, m, n, q, and BRIDGE are defined in the specification. The invention also relates to pharmaceutical compositions and methods for use thereof. The novel compounds are useful for preventing, treating or ameliorating diseases and disorders, such as obesity, type 2 diabetes, the metabolic syndrome, insulin resistance, and dyslipidemia, among others.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: August 22, 2023
    Assignee: Janssen Pharmaceutica NV
    Inventors: Mark Macielag, Raymond J. Patch, Rui Zhang, Martin A. Case, Mark J. Wall, Yue-Mei Zhang
  • Patent number: 11712512
    Abstract: A low-cost medical pump for ambulatory use provides an improved IV line cartridge attachment allowing for single handed, low force release while preventing inadvertent IV line cartridge release. A rotatable side lever minimizes the force required to move the locking elements against a spring biased force urging the locking elements to a locking position.
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: August 1, 2023
    Assignee: Zyno Medical, LLC
    Inventors: Chaoyoung Lee, Zhenhua Mao, Frederick Lee, Mei Zhang
  • Patent number: 11704314
    Abstract: Embodiments of the present invention relate to a method, system, and computer program product for multiplexing data operation. In some embodiments, a method is disclosed. A query for at least one table comprising a plurality of data records is received. The query indicating a plurality of data operations to be performed on the plurality of data records. The plurality of data operations are combined into a target data operation. An intermediate result of the query is generated by performing the target data operation on the plurality of data records. A final result of the query is determined based on the intermediate result. In other embodiments, a system and a computer program product are disclosed.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: July 18, 2023
    Assignee: International Business Machines Corporation
    Inventors: Shuo Li, Xiaobo Wang, Sheng Yan Sun, Hong Mei Zhang
  • Patent number: 11704151
    Abstract: A method, system, and computer program product to plan and schedule executions of various utility tasks of a utility command during a maintain window, the method including receiving a utility command. The method may also include identifying possible utility tasks used to execute the utility command. The method may also include determining preferred utility tasks. The method may also include calculating a degree of parallelism for the preferred utility tasks. The method may also include generating a utility execution plan for the utility command. The method may also include analyzing the utility execution plan against resource constraints of a time window and sub time windows of the time window. The method may also include generating a time window execution plan for each sub time window of the sub time windows. The method may also include updating the utility execution plan with the time window execution plans.
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: July 18, 2023
    Assignee: International Business Machines Corporation
    Inventors: Hong Mei Zhang, Xiaobo Wang, Sheng Yan Sun, Shuo Li
  • Publication number: 20230222150
    Abstract: An embodiment includes executing a querying process that returns database documents containing text associated with a database environment. The embodiment tokenizes the database documents into a series of n-gram tokens and groups the tokens into topic classes using natural language processing (NLP). The embodiment also generates a feature map by applying a convolution layer to an image that depicts a database structure graph of the database environment. The embodiment detects an architectural element in the image by applying a region proposal network (RPN) to the feature map and classifies the architectural element into one of the plurality of topic classes using a trained neural network. The embodiment renders, responsive to a user selection of the architectural element, an overlay depicting information about the architectural element using text and other architectural elements that are in a same topic class as the user-selected architectural element.
    Type: Application
    Filed: January 10, 2022
    Publication date: July 13, 2023
    Applicant: International Business Machines Corporation
    Inventors: Sheng Yan Sun, Shuo Li, Xiaobo Wang, Hong Mei Zhang
  • Patent number: D995868
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: August 15, 2023
    Assignee: JIAXING SUPER LIGHTING ELECTRIC APPLIANCE CO., LTD
    Inventors: Tao Jiang, Ming-Bin Wang, Chen-Kun Chen, Dong-Mei Zhang
  • Fan
    Patent number: D998133
    Type: Grant
    Filed: May 31, 2021
    Date of Patent: September 5, 2023
    Inventor: Mei Zhang