Patents by Inventor Meredith JONES
Meredith JONES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200222635Abstract: A sensor device removably attachable to a drug delivery device includes a sensing arrangement arranged within the sensor device and circuitry configured to process signals provided by the sensing arrangement. The sensing arrangement is configured such that, when the sensor device is attached to the drug delivery device, the sensing arrangement is operable to read encoded information present on a rotatable component internal to the drug delivery device and that is able to be sensed through a window or aperture of the drug delivery device, and is operable to sense through the window or aperture at least a part of a drive mechanism of the drug delivery device. The circuitry is configured to determine information relating to a set dose, and to determine information relating to whether the drug delivery device is in a dose setting mode or whether the device is in a dose delivery mode.Type: ApplicationFiled: March 19, 2020Publication date: July 16, 2020Inventors: Christian Rehbein, Samuel Steel, Anthony Paul Morris, Matthew Meredith Jones, Robert Veasey, Richard James Vincent Avery, William Marsh
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Patent number: 10688246Abstract: The present disclosure relates to an injection device for setting and dispensing of a dose of a medicament, the device including an elongated housing to accommodate a cartridge filled with the medicament and sealed with a piston, a piston rod extending along a first axis and being threadedly or slidingly engaged with the housing to apply a distally directed thrust to the piston of the cartridge, a drive member rotationally or threadedly engaged with the piston rod and having a wheel section or geared section, and a drive sleeve extending along a second axis at a radial distance from the first axis and having a geared section to mesh with the wheel section or geared section of the drive member, wherein a first radial distance between first and second axes at a distal end of the drive sleeve differs from a second radial distance between first and second axes at a proximal end of the drive sleeve.Type: GrantFiled: December 9, 2015Date of Patent: June 23, 2020Assignee: SanofiInventors: Anthony Paul Morris, Matthew Meredith Jones, Oliver Benjamin Brown
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Patent number: 10675418Abstract: A drug delivery device includes a piston rod which extends along a longitudinal axis of the drug delivery device, wherein the piston rod is adapted to apply an axial load in the distal direction to a cartridge bung in order to dispense a medicament contained in the cartridge. In order to improve the convenience of the injection process and to mitigate the risk of underdosing due to a blocked needle a cartridge bung load indicator is provided, located at the distal end of the piston rod and adapted to abut against the cartridge bung, wherein the cartridge bung load indicator comprises an indicator element that audibly, tangibly and/or visually indicates a load state of the piston rod to the user.Type: GrantFiled: July 7, 2016Date of Patent: June 9, 2020Assignee: SanofiInventors: Oliver Charles Gazeley, James Lewis Gareth, Daniel Thomas De Sausmarez Lintell, Matthew Meredith Jones, Robert Frederick Veasey, David Plumptre, Anthony Paul Morris
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Patent number: 10625022Abstract: A sensor device removably attachable to a drug delivery device includes a sensing arrangement arranged within the sensor device and circuitry configured to process signals provided by the sensing arrangement. The sensing arrangement is configured such that, when the sensor device is attached to the drug delivery device, the sensing arrangement is operable to read encoded information present on a rotatable component internal to the drug delivery device and that is able to be sensed through a window or aperture of the drug delivery device, and is operable to sense through the window or aperture at least a part of a drive mechanism of the drug delivery device. The circuitry is configured to determine information relating to a set dose, and to determine information relating to whether the drug delivery device is in a dose setting mode or whether the device is in a dose delivery mode.Type: GrantFiled: December 9, 2016Date of Patent: April 21, 2020Assignee: Sanofi-Aventis Deutschland GMBHInventors: Christian Rehbein, Samuel Steel, Anthony Paul Morris, Matthew Meredith Jones, Robert Veasey, Richard James Vincent Avery, William Marsh
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Patent number: 10603435Abstract: The disclosure is directed to a drive mechanism for use in a drug delivery device having a cartridge, the mechanism comprising a base element, a toothed piston rod movable from a first retracted position corresponding to a full cartridge to a second extended position corresponding to an empty cartridge, wherein the piston rod is guided within and movable relative to the base portion, and a drive gear having a pinion, which is rotatably held in the base element and in meshed engagement with the toothed piston rod, wherein the toothed piston rod comprises multiple rigid rod pieces which are connected by hinges, and a drive spring, which is fixed to the base element with one end and fixed to the drive gear with another end and which exerts a force or torque to the drive gear for rotating the drive gear relative to the base element, which rotation results in a movement of the toothed piston rod.Type: GrantFiled: December 8, 2015Date of Patent: March 31, 2020Assignee: SanofiInventors: William Geoffrey Arthur Marsh, Matthew Meredith Jones, Joseph Butler, Anthony Paul Morris
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Patent number: 10576212Abstract: The present disclosure is generally directed to a dose setting mechanism and a drug delivery device herewith, i.e. a handheld injection device for selecting and dispensing a number of user variable doses of a medicament. The dose setting mechanism comprises a dose setting member rotatable relative to a housing in a first direction for dose setting and in an opposite second direction for dose correcting, a cam ring and a coupling member coupled to a drive member. A ramped interface is provided between the dose setting member and the cam ring such that rotation of the dose setting member relative to the cam ring in the second direction causes axial displacement of the cam ring.Type: GrantFiled: February 8, 2015Date of Patent: March 3, 2020Assignee: SanofiInventors: William Geoffrey Arthur Marsh, Matthew Meredith Jones
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Patent number: 10576214Abstract: The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament and to a non-numerical display for such a device. The display comprises a housing with at least one window, a dosing element movable relative to the housing during dose setting and/or dose dispensing, and a movable indicator element visible through the at least one window The indicator element is coupled to the dosing element and/or to the housing such that it moves not proportional to the dosing element.Type: GrantFiled: November 24, 2015Date of Patent: March 3, 2020Assignee: SanofiInventors: Robert Frederick Veasey, Paul Griffin, William Geoffrey Arthur Marsh, Matthew Meredith Jones, Richard James Vincent Avery
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Patent number: 10471218Abstract: The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing (10), a dose selector (80) operable to set a dose by rotation relative to the housing (10), a number sleeve (60) arranged within the housing (10) such that at least a portion of the number sleeve (60) is visible through a first aperture (11b) in the housing (10), and a piston rod (30) coupled to the housing (10) and to a drive sleeve (40). Rotation of the drive sleeve (40) relative to the housing (10) causes the piston rod (30) to translate relative to the housing (10). The piston rod (30) is coupled to the housing (10) via a threaded interface (16, 31) with at least two different pitches.Type: GrantFiled: July 1, 2015Date of Patent: November 12, 2019Assignee: SanofiInventors: William Geoffrey Arthur Marsh, Anthony Paul Morris, Joseph Butler, Matthew Meredith Jones, Samuel Keir Steel, Richard James Vincent Avery
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Patent number: 10471219Abstract: The present disclosure relates to a drug delivery device, comprising a housing, a cartridge, the cartridge containing a drug in a quantity sufficient for a plurality of doses of the drug, a bung, the bung being movably retained within the cartridge to dispense a dose of the drug from the cartridge upon movement of the bung with respect to the cartridge, and a drive mechanism, the drive mechanism being operable to transfer a driving force to the bung to dispense the dose of the drug from the cartridge. The drug delivery device is configured such that the maximal driving force which is transferrable to the bung via the drive mechanism varies and is adjusted to the current position of the bung within the cartridge.Type: GrantFiled: November 24, 2015Date of Patent: November 12, 2019Assignee: SanofiInventors: Matthew Meredith Jones, William Geoffrey Arthur Marsh, Anthony Paul Morris, Samuel Keir Steel
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Patent number: 10441725Abstract: A dose setting mechanism for a drug delivery device includes a primary drug delivery assembly and a secondary drug delivery assembly. The dose setting mechanism includes a primary dose dial component for setting a dose in the primary drug delivery assembly and a secondary dose dial component for setting a dose in the secondary drug delivery assembly. The primary dose dial component and the secondary dose dial component are configured to rotate during dose setting. A gear mechanism is configured such that in a first phase of the dose setting, rotation of the primary dose dial component is transferred to the secondary dose dial component and such that in a second phase of the dose setting, the secondary dose dial component is decoupled from the primary dose dial component such that rotation of the primary dose dial component is prevented from being transferred to the secondary dose dial component.Type: GrantFiled: May 27, 2015Date of Patent: October 15, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventors: Matthew Meredith Jones, Samuel Keir Steel, Neal Alexander Blundred, Joseph Butler, Robert Frederick Veasey, David Plumptre
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Patent number: 10426890Abstract: The invention is directed to drug delivery device comprising a primary drug delivery assembly (3) with a primary dose dial sleeve (17) and a secondary drug delivery assembly (4) with a secondary drive sleeve (24). For user selection, a selection switch (48) is movable between a first, a second and a third position and a clutch (49) is connected to the selection switch (48) such that movement of the selection switch (48) causes rotation of the clutch (49). A secondary drive sleeve (24) is configured to rotate and to engage the clutch (49), wherein the clutch (49) is configured to transfer rotation to the secondary drive sleeve (24) when the selection switch (48) is moved from the first position into the second position and to disengage from the secondary drive sleeve (24) when the selection switch (48) is moved from the first into the third position.Type: GrantFiled: May 27, 2015Date of Patent: October 1, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventors: Anthony Paul Morris, Joseph Butler, David Plumptre, Matthew Meredith Jones, Robert Frederick Veasey, Neal Alexander Blundred, Samuel Keir Steel
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Publication number: 20190231979Abstract: A drug delivery device comprising a housing body; a piston rod configured to rotate in a first direction during dose dispensing under a driving force; and a threaded insert, wherein the piston rod is in threaded engagement with the threaded insert such that during dose dispensing, the piston rod displaces axially in a distal direction relative to the threaded insert for displacement of a cartridge bung. The threaded insert is movable relative to a stop provided in the housing body and a resilient means is provided to bias the threaded insert against the stop so that rotation of the piston rod causes the threaded insert to move away from the stop in response to reaction forces acting on the piston rod (in a proximal direction when the reaction forces exceed the biasing force of the resilient means.Type: ApplicationFiled: June 30, 2017Publication date: August 1, 2019Inventors: Markus Ploch, Aled Meredydd James, Anthony Paul Morris, Matthew Meredith Jones, Oliver Charles Gazeley, Robert Frederick Veasey, David Aubrey Plumptre
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Patent number: 10307544Abstract: The disclosure is directed to a differential gear mechanism for a drug delivery device with a primary drug delivery assembly and a secondary drug delivery assembly, wherein the primary drug delivery assembly comprises a primary dose dial sleeve and wherein the secondary drug delivery assembly comprises a secondary drive sleeve. The disclosure is also directed to a respective drug delivery device.Type: GrantFiled: May 27, 2015Date of Patent: June 4, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventors: Matthew Meredith Jones, Samuel Keir Steel, Neal Alexander Blundred, Joseph Butler, Robert Frederick Veasey, David Plumptre, Anthony Paul Morris
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Publication number: 20190116409Abstract: An audio device securing apparatus includes a button-pin stay including a pin coupled thereto. The pin projects outwards away from the button-pin stay. The pin includes a pointed end facing away from the button-pin stay. The pointed end of the pin is configured to pierce a shirt collar, tie or jacket. A magnet faces away from the button-pin stay. The magnet is dimensioned and positioned to hold an ear bud including a metal component under the shirt collar. A pin stop is coupled to the magnet. The pin stop is dimensioned and positioned to house the pointed end of the pin.Type: ApplicationFiled: October 17, 2018Publication date: April 18, 2019Inventor: Giles Meredith Jones
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Publication number: 20190077841Abstract: High-yield mammalian transient expression systems can include a cell culture media (particularly serum free, non-animal derived, and/or chemically defined media) for introducing macromolecules and compounds (e.g., nucleic acid molecules) into cells (e.g., eukaryotic cells). Cells containing such introduced materials can then be cultured in the cell culture media. In particular, the invention allows introduction of nucleic acid molecules (e.g., vectors) into cells (particularly mammalian cells) and expression of proteins encoded by the nucleic acid molecules in the cells. The invention obviates the need to change the cell culture medium each time a different procedure is performed with the cells (e.g., culturing cells vs. transfecting cells). The invention also relates to compositions and kits useful for culturing and transforming/transfecting cells.Type: ApplicationFiled: July 26, 2018Publication date: March 14, 2019Inventors: Sanjay VASU, Chao Yan LIU, Jeffrey ROGERS, Maria CISNEROS, Jingqiu LI, Henry CHIOU, Meredith JONES
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Publication number: 20180369490Abstract: A sensor device removably attachable to a drug delivery device includes a sensing arrangement arranged within the sensor device and circuitry configured to process signals provided by the sensing arrangement. The sensing arrangement is configured such that, when the sensor device is attached to the drug delivery device, the sensing arrangement is operable to read encoded information present on a rotatable component internal to the drug delivery device and that is able to be sensed through a window or aperture of the drug delivery device, and is operable to sense through the window or aperture at least a part of a drive mechanism of the drug delivery device. The circuitry is configured to determine information relating to a set dose, and to determine information relating to whether the drug delivery device is in a dose setting mode or whether the device is in a dose delivery mode.Type: ApplicationFiled: December 9, 2016Publication date: December 27, 2018Inventors: Christian Rehbein, Samuel Steel, Anthony Paul Morris, Matthew Meredith Jones, Robert Veasey, Richard James Vincent Avery, William Marsh
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Publication number: 20180304026Abstract: The disclosure relates to a drug delivery device for mechanically dispensing a dose of a medicament. The drug delivery device includes a ratchet mechanism adapted to emit an audible and/or tactile feedback during dispensing the dose of medicament. The ratchet mechanism includes a flexible arm and a toothed profile. A free end of the flexible arm is configured to engage with the toothed profile and to perform a relative rotational movement thereto during dispensing the dose of medicament, thereby generating the audible and/or tactile feedback, and the flexible arm extends in a plane parallel to a rotational axis of the flexible arm.Type: ApplicationFiled: August 8, 2016Publication date: October 25, 2018Inventors: Anthony Paul MORRIS, William MARSH, Matthew Meredith JONES
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Publication number: 20180250475Abstract: The disclosure provides a piston rod configured to engage a housing of a drug delivery device, wherein the piston rod comprises an outer thread that corresponds with an inner thread of the housing, characterized by a support element (that is configured as a supplement thread section of the outer thread, wherein the support element comprises a lead-in for assembly of the drug delivery device and wherein the lead-in is distally spaced from another lead-in arranged on the distal outer thread end. The disclosure further provides a drug delivery device comprising such a piston rod and a method for assembling such a drug delivery device.Type: ApplicationFiled: August 8, 2016Publication date: September 6, 2018Inventors: Anthony Paul MORRIS, William MARSH, Matthew Meredith JONES
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Patent number: 10066000Abstract: High-Yield mammalian transient expression systems can include a cell culture media (particularly serum free, non animal derived, and/or chemically defined media) for introducing macromolecules and compounds (e.g., nucleic acid molecules) into cells (e.g., eukaryotic cells). Cells containing such introduced materials can then be cultured in the cell culture media. In particular, the invention allows introduction of nucleic acid molecules (e.g., vectors) into cells (particularly mammalian cells) and expression of proteins encoded by the nucleic acid molecules in the cells. The invention obviates the need to change the cell culture medium each time a different procedure is performed with the cells (e.g., culturing cells vs. transfecting cells). The invention also relates to compositions and kits useful for culturing and transforming/transfecting cells.Type: GrantFiled: May 2, 2013Date of Patent: September 4, 2018Assignee: Life Technologies CorporationInventors: Sanjay Vasu, Henry Chiou, Jeffrey Rogers, Maria Isabel Cisneros, Jingqiu Li, Chao Yan Liu, Meredith Jones
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Publication number: 20180200457Abstract: A drug delivery device includes a piston rod which extends along a longitudinal axis of the drug delivery device, wherein the piston rod is adapted to apply an axial load in the distal direction to a cartridge bung in order to dispense a medicament contained in the cartridge. In order to improve the convenience of the injection process and to mitigate the risk of underdosing due to a blocked needle a cartridge bung load indicator is provided, located at the distal end of the piston rod and adapted to abut against the cartridge bung, wherein the cartridge bung load indicator comprises an indicator element that audibly, tangibly and/or visually indicates a load state of the piston rod to the user.Type: ApplicationFiled: July 7, 2016Publication date: July 19, 2018Inventors: Oliver Charles Azeley, James Lewis Gareth, Daniel Thomas De Sausmarez Lintell, Matthew Meredith Jones, Robert Frederick Veasey, David Plumptre, Anthony Paul Morris