Abstract: The present disclosure relates to antibodies and antibody conjugates, for instance antibody drug conjugates, with binding specificity for receptor tyrosine kinase orphan receptor 1 (ROR1) and its isoforms and homologs, and compositions comprising the antibodies or antibody conjugates, including pharmaceutical compositions. Also provided are methods of producing the antibodies and antibody conjugates and compositions thereof as well as methods of using the antibodies and antibody conjugates and compositions thereof, such as in therapeutic and diagnostic methods.

Abstract: The technology disclosed herein enables configuration and sharing of a coverage map which displays asset data. In various implementations, an asset owner provides access to select portions of asset data, such as vehicle performance data, to an end-user. The asset owner configures a coverage map to display the selected data according to the type of asset data to be displayed, the scope of the data to be displayed, and other map attributes. Once configured, a URL is generated which the fleet operator provides to the end-user.

Abstract: A flexible mechanism-based anti-backlash device for a planetary gear train, a gearbox, and a robot joint are provided. The anti-backlash device includes an integrated flexible planet carrier, an adjusting screw and a spring, the integrated flexible planet carrier is provided with a moving platform, the moving platform is provided with a spring hole, and the spring is sleeved outside the screw and is installed in the spring hole; when the threaded connection depth of the adjusting screw and the integrated flexible planet carrier reaches or exceeds a set depth, the adjusting screw can extrude the spring to make the moving platform generate elastic movement along a radial direction of the integrated flexible planet carrier, and the radial elastic movement is transformed into circumferential elastic rotation of a planet carrier bearing hole around the center of the planet carrier through an elastic connector.

Abstract: A rocker panel for use in a vehicle, the rocker panel includes an outboard plate, an inboard plate, and a reinforcement structure. The reinforcement structure is disposed between the inboard plate and the outboard plate. The reinforcement structure includes one or more discrete steel tubes extending longitudinally between the outboard plate and the inboard plate.

Abstract: A sole data collection device and a sole data collection method are disclosed. The sole data collection device includes an image capture module, a temperature detection module and a monofilament testing module. The sole data collection device is used for collecting the sole data of a user, and the sole data is transmitted to a cloud server. The sole data collection device and the sole data collection method are not only convenient for a user to collect sole data at home at any time, but also allow the user's caregiver and/or relevant medical care personnel to extract the sole data from the cloud server to screen the user's plantar condition, so as to solve the problem that it is time-consuming and costly to go to a medical institution for relevant examinations.

Abstract: The present disclosure relates to antibodies and antibody conjugates, for instance antibody drug conjugates, with binding specificity for receptor tyrosine kinase orphan receptor 1 (ROR1) and its isoforms and homologs, and compositions comprising the antibodies or antibody conjugates, including pharmaceutical compositions. Also provided are methods of producing the antibodies and antibody conjugates and compositions thereof as well as methods of using the antibodies and antibody conjugates and compositions thereof, such as in therapeutic and diagnostic methods.

Abstract: The present disclosure discloses a method, apparatus, device, and storage medium for training a model, relates to the technical fields of knowledge graph, natural language processing, and deep learning. The method may include: acquiring a first annotation data set, the first annotation data set including sample data and a annotation classification result corresponding to the sample data; training a preset initial classification model based on the first annotation data set to obtain an intermediate model; performing prediction on the sample data in the first annotation data set using the intermediate model to obtain a prediction classification result corresponding to the sample data; generating a second annotation data set based on the sample data, the corresponding annotation classification result, and the corresponding prediction classification result; and training the intermediate model based on the second annotation data set to obtain a classification model.

Abstract: A protein inhibitor or degrading agent, a pharmaceutical composition comprising same and a pharmaceutical use. Provided are a compound represented by general formula (I), and a pharmaceutical composition containing same. Also disclosed are an application of the compound of the general formula as a protein inhibitor and/or a protein degrading agent and a pharmaceutical use.

Abstract: An apparatus for containing a portion of a vehicle battery assembly incudes a tray. The tray is configured to receive the portion of the vehicle battery assembly. The tray defines a floor, a front wall, a rear wall, and a pair of sidewalls extending from the front wall to the rear wall. The tray includes a first steel material and a second steel material. The first steel material is joined with the second steel material to form a single contiguous part. The first steel material defines a substantial majority of the floor. The second steel material is disposed at two or more corners of the tray.

Abstract: A stress-based comprehensive method and system for evaluating state of health of a power battery, medium and device, the method including: acquiring the stress and capacity of a battery charging and discharging cycle; correlating between acquired stress and capacity, calculating the battery charge and health states based on stress; evaluating the battery charge state by correlating the stress and battery charge state; acquiring a current battery capacity and internal resistance and predicting remaining useful battery life to calculate current capacity-based and internal resistance-based states of battery health respectively; and calculating a weighted sum of the battery state of health based on stress, the capacity-based and the internal resistance-based states of battery health, and obtaining a comprehensively evaluated state of battery health by combining the weighted sum and evaluated state of battery charge.

Abstract: A rocker panel for use in a vehicle, the rocker panel includes an outboard plate, an inboard plate, and a reinforcement structure. The reinforcement structure is disposed between the inboard plate and the outboard plate. The reinforcement structure includes one or more discrete steel tubes extending longitudinally between the outboard plate and the inboard plate.

Abstract: A network system dynamically determines a route, including start and end points, for vehicles in a transportation network. The transportation network receives a service request from a user of the transportation network including an origin location for the trip and a destination location for the trip. The transportation network then generates a waypoint plan for one or more vehicles, which includes the requested origin and destination in addition to any previously requested origins and destinations included in the vehicles current route. The network system then determines a directionality for each of the waypoints in the waypoint plan and retrieves candidate start and end points that have an associated directionality within a threshold angle of the directionality of each waypoint and are proximate to the waypoint. The network system evaluates each combination of retrieved candidate points to select a route for the vehicle.

Abstract: The invention generally relates to improved processes for the preparation of intermediates of a cyclic dinucleotide which is useful as a STING agonist.

Abstract: A network system dynamically determines a route, including start and end points, for vehicles in a transportation network. The transportation network receives a service request from a user of the transportation network including an origin location for the trip and a destination location for the trip. The transportation network then generates a waypoint plan for one or more vehicles, which includes the requested origin and destination in addition to any previously requested origins and destinations included in the vehicles current route. The network system then determines a directionality for each of the waypoints in the waypoint plan and retrieves candidate start and end points that have an associated directionality within a threshold angle of the directionality of each waypoint and are proximate to the waypoint. The network system evaluates each combination of retrieved candidate points to select a route for the vehicle.

Abstract: Provided is a method for analyzing the stability of a PMSG-WT connected to a weak power grid considering the influence of power control. New energy power generation mostly uses a perturbation and observation (P&O) method for maximum power point tracking, and nonlinear discontinuous links therein make stability analysis difficult. The present application analyzes the stability of the PMSG-WT connected to the weak grid system based on a describing function method, and fully considers the nonlinear discontinuous links in the power loop, thus making the analysis result more accurate. At the same time, the describing function method is a method that can quantitatively calculate the frequency and amplitude of oscillation. The analysis method of the present application can provide a powerful and good reference for oscillation suppression and controller design.

Abstract: The present invention provides a high-efficient magnesium ion removal system for salt lake brine based on in situ alkali production using bipolar membrane electrochemical process, it is constructed with cathode, cathode cell, anode, anode cell, and anion exchange membranes, bipolar membranes, acid cells, alkali cells, mesh materials for precipitate aggregation, acid-washing cells.

Abstract: Methods and kits for genome-wide identification of chromatin interactions in a cell are provided.

Abstract: Provided are a method, a device and electronic equipment for detecting a stability of a generator set in a power system. The method includes following steps: determining a target matrix by using Liapunov's direct method based on a state space matrix corresponding to power management unit (PMU) data; obtaining a state deviation corresponding to the PMU data and an oscillation curve corresponding to the state deviation in a case of determining the power system being in a stable state according to the target matrix; determining extreme point values corresponding to the oscillation curve at each oscillation; and evaluating a working state of the generator set in the power system according to the extreme point values.

Abstract: The present disclosure provides a method, a terminal, and a storage medium for displaying application interfaces. The method includes displaying the application interfaces of a first group of split-screen applications among m split-screen applications in a split-screen manner in a display screen; wherein each group of split-screen applications includes n adjacent split-screen applications among the m split-screen applications, m being an integer greater than or equal to n, and n being an integer greater than or equal to 2; receiving an application switching operation; and displaying the application interfaces of a second group of split-screen applications among the m split-screen applications in the split-screen manner in the display screen based on the application switching operation; wherein the second group of split-screen applications is partially or fully different from the first group of split-screen applications.

Abstract: A method for extracting a kansei adjective of a product based on principal component analysis and explanation (PCA-E) includes constructing a product kansei evaluation vector matrix through original kansei adjectives; performing dimensionality reduction through PCA; and determining, based on principal component load factors, kansei adjectives representing principal components. In this way, the kansei adjectives extracted are explanatory to help users understand the selected kansei adjectives and make accurate evaluation.