Abstract: The present invention relates generally to olefin metathesis. In some embodiments, the present invention provides methods for Z-selective ring-closing metathesis.

Abstract: The present invention relates to methods and compositions for detecting, evaluating, and/or mapping 5-methyl-modified and/or 5-hydroxylmethyl-modified cytosine bases within a nucleic acid molecule.

Abstract: Methods are provided for preparing TiO2 nanofiltration membranes for water purification are provided. The method can include supplying a titanium precursor gas into a reaction chamber, where the titanium precursor gas reacts with a base support of an anodic aluminum oxide, and the base support of an anodic aluminum oxide has a surface defining a plurality of pores therein. The reaction chamber can then be evacuated to remove any unreacted titanium precursor gas, and an alkoxide precursor gas can be supplied into a reaction chamber such that the alkoxide precursor gas reacts to with the titanium on the base support to form a hybrid titanium alkoxide. Thereafter, the base support cab be heated to remove the organic component to leave titanium oxide on the surface of the base support.

Abstract: A method for separating the components of a mixture containing methyl methacrylate, water, and methanol in which the mixture is dehydrated in a first stage membrane unit, producing a dehydrated mixture. Methanol in the dehydrated mixture is removed in a second stage membrane unit, producing a retentate stream containing methyl methacrylate and substantially no said methanol.

Abstract: Methods are generally provided for forming a membrane. In one embodiment, the method includes: dispersing GO nanoparticles in a solvent; depositing the GO nanoparticles on a support to form a GO membrane; and reducing the GO membrane to form a rGO membrane. Also provided is the rGO membrane formed from such methods, along with a plurality of stacked rGO layers. Methods are also provided for separating water from a water/oil emulsion by, for example, passing water through the rGO membrane.

Abstract: The present invention relates generally to olefin metathesis. In some embodiments, the present invention provides methods for Z-selective ring-closing metathesis.

Abstract: A highly cost-efficient method and process for producing oxygen from a gaseous mixture such as air results in substantial energy savings compared to conventional methods. The gaseous mixture is fed to a membrane absorber in which oxygen from the gas is absorbed, through a first membrane by an oxygen-absorbing liquid that possesses suitable absorption and desorption properties. The resulting oxygen-rich carrier liquid is fed to a membrane desorber in which oxygen from the liquid is desorbed through a second membrane, suitably with the aid of a vacuum. The oxygen product suitably has greater than 95% purity, or greater than 99% purity.

Abstract: A graphene-based membrane, along with its methods of formation and use, is provided. The graphene membrane includes at least two graphene-oxide layers. Each graphene-oxide layer has a plurality of graphene-oxide flakes, with each graphene-oxide flake having a planar graphene structure with oxygen moieties extending therefrom. The graphene-based membrane can have a thickness of about 2 nm to about 20 nm. Such a graphene-based membrane can be utilized to remove ions from water.

Abstract: This application describes compounds and methods that can inhibit Scavenger receptor class B, type I (SR-BI) activity, which compounds and methods can used, for example, to mediate high-density lipoprotein (HDL) lipid uptake and treat hepatitis C viral infections.

Abstract: Adsorbent pellets coated with an outer nano-porous layer can be loaded with gas at loading pressures of 250 bar or greater, enabling a much higher loading than can be achieved at low pressures. The nano-porous layer provides nano-valves which can be sealed with an adsorbate such as ethanol or a hydrocarbon to close the nano-valves. The closed nano-valves maintain the high loading pressure inside the adsorbent pellets, and thus maintain the gas loading, during storage of the loaded nano-valved adsorbent pellets at much lower pressure. To release the gas, the nano-porous layer can be heated to a temperature sufficient to vaporize the adsorbate and open the nano-valves.

Abstract: Adsorbent pellets coated with an outer nano-porous layer can be loaded with gas at loading pressures of 250 bar or greater, enabling a much higher loading than can be achieved at low pressures. The nano-porous layer provides nano-valves which can be sealed with an adsorbate such as ethanol or a hydrocarbon to close the nano-valves. The closed nano-valves maintain the high loading pressure inside the adsorbent pellets, and thus maintain the gas loading, during storage of the loaded nano-valved adsorbent pellets at much lower pressure. To release the gas, the nano-porous layer can be heated to a temperature sufficient to vaporize the adsorbate and open the nano-valves.

Abstract: This application describes compounds and methods that can inhibit Scavenger receptor class B, type I (SR-BI) activity, which compounds and methods can be used, for example, to mediate high-density lipoprotein (HDL) lipid uptake and treat hepatitis C viral infections. The compounds have the formula: wherein R1 and R2 are independently H, halogen, cyano, haloalkyl, haloalkyloxy or OMe; or R1 and R2 together are —O—CH2— or -0- CF2—O—; R3 is H, halogen, cyano, haloalkyl or haloalkyloxy; R4 is C1-6alkyl, C3-6cycloalkyl, C3-6cycloalkylmethyl or C3-6cycloheteroalkyl, wherein the heteroatom is N or 0; R5 is H or CH3; R6 is C1-6alkyl or C3-6cycloalkyl; and A, B, D and E are each, independently, CH, N, 0 or S, wherein at least one of A, B, D and E is N, and another of A, B, D and E is N, 0 or S.

Abstract: Methods for forming an ultrathin GO membrane are provided. The method can include: dispersing a single-layered graphene oxide powder in deionized water to form a single-layered graphene oxide dispersion; centrifuging the graphene oxide dispersion to remove aggregated graphene oxide material from the single-layered graphene oxide dispersion; thereafter, diluting the single-layered graphene oxide dispersion by about ten times or more through addition of deionized water to the graphene oxide dispersion; and thereafter, passing the single-layered graphene oxide dispersion through a substrate such that a graphene oxide membrane is formed on the substrate. Filtration membranes are also provided and can include: a graphene oxide membrane having a thickness of about 1.8 nm to about 180 nm, with the graphene oxide membrane comprises about 3 to about 30 layers of graphene oxide flakes.

Abstract: The present invention relates generally to olefin metathesis. In some embodiments, the present invention provides methods for Z-selective ring-closing metathesis.

Abstract: Methods for forming an ultrathin GO membrane are provided. The method can include: dispersing a single-layered graphene oxide powder in deionized water to form a single-layered graphene oxide dispersion; centrifuging the graphene oxide dispersion to remove aggregated graphene oxide material from the single-layered graphene oxide dispersion; thereafter, diluting the single-layered graphene oxide dispersion by about ten times or more through addition of deionized water to the graphene oxide dispersion; and thereafter, passing the single-layered graphene oxide dispersion through a substrate such that a graphene oxide membrane is formed on the substrate. Filtration membranes are also provided and can include: a graphene oxide membrane having a thickness of about 1.8 nm to about 180 nm, with the graphene oxide membrane comprises about 3 to about 30 layers of graphene oxide flakes.

Abstract: Ultra-thin porous films are deposited on a substrate in a process that includes laying down an organic polymer, inorganic material or inorganic-organic material via an atomic layer deposition or molecular layer deposition technique, and then treating the resulting film to introduce pores. The films are characterized in having extremely small thicknesses of pores that are typically well less than 50 nm in size.

Abstract: The present invention relates generally to olefin metathesis. In some embodiments, the present invention provides methods for Z-selective ring-closing metathesis.

Abstract: An apparatus for gas separation a composite gas separation membrane having a gas separation layer disposed on a surface of a porous support. The gas separation layer has a plurality of gas permeable inorganic nano-particles embedded in a dense polymer forming substantially only discrete gas transport channels through the dense polymer layer, wherein direct fluid communication is provided from a feed side of the composite gas separator membrane to the porous support. Preferably, the inorganic nano-particles are porous molecular sieve particles, such as SAPO-34, ALPO-18, and Zeolite Y nano-particles.

Abstract: Ultra-miniature surface-mountable optical pressure sensor is constructed on an optical fiber. The sensor design utilizes an angled fiber tip which steers the optical axis of the optic fiber by 90°. The optical cavity is formed on the sidewall of the optic fiber. The optical cavity may be covered with a polymer-metal composite diaphragm to operate as a pressure transducer, Alternatively, a polymer-filled cavity may be constructed which does not need a reflective diaphragm. The sensor exhibits a sufficient linearity over the broad pressure range with a high sensitivity. The sensitivity of the sensor may he tuned by controlling the thickness of the diaphragm. Methods of batch production of uniform device-to-device optical pressure sensors of co-axial and cross-axial configurations are presented.

Abstract: A method for separating the components of a mixture containing methyl methacrylate, water, and methanol in which the mixture is dehydrated in a first stage membrane unit, producing a dehydrated mixture. Methanol in the dehydrated mixture is removed in a second stage membrane unit, producing a retentate stream containing methyl methacrylate and substantially no said methanol.