Abstract: An atomizing nozzle structured particularly for nasal therapy. Preferred embodiments include a 2-piece atomizing nozzle structured to couple with luer-locking structure carried by a syringe. Such an atomizing nozzle includes a nasal stopper and a stem. A preferred nasal stopper includes a distal tip sized for insertion into a nostril of a human child, with a proximal shield portion being structured to resist over-insertion of a discharge orifice into the nostril. A nasal stopper desirably provides a centering function to urge the discharge orifice away from a nasal wall. One operable stem is structured to couple with the stopper and desirably carries unitary thread structure at a proximal end. A second operable stem is structured as a unitary part of the nasal stopper and also desirably carries unitary thread structure at a proximal end. Certain embodiments may also include spacer structure configured to reduce a dead volume inside the atomizing nozzle.

Abstract: Integrated core-shell investment casting molds include a filament structure corresponding to a cooling hole pattern in the surface of the turbine blade, stator vane, or shroud.

Abstract: Integrated core-shell investment casting molds include a filament structure corresponding to a cooling hole pattern in the surface of the turbine blade, stator vane, or shroud.

Abstract: The disclosure relates to compounds of Formula I, or pharmaceutically acceptable salts thereof, Formula (I) as defined herein. Compounds according to Formula I are pharmacologically effective as lysyl oxidase (LOX) inhibitors and are believed to be useful in the treatment of, for instance, cancer.

Abstract: A method of treatment comprises administering, via data processing hardware, to a first set of one or more users, a digital therapeutic, wherein the digital therapeutic comprises at least cognitive behavioral therapy content, administering, via the data processing hardware, to a second set of one or more users, at least one of a sham or a placebo digital therapeutic, wherein the at least one sham or placebo digital therapeutic does not comprise any cognitive behavioral therapy content, determining, via the data processing hardware, a first efficacy value associated with the digital therapeutic based on an analysis of engagement of the first set of one or more users with the digital therapeutic, determining, via the data processing hardware, a second efficacy value associated with the at least one sham or placebo digital therapeutic based on analysis of engagement of the second set of one or more users with the sham or placebo digital therapeutic, determining, via the data processing hardware, a third efficacy

Abstract: A system and process may be used to test water samples to measure ATP and/or estimate a microbial population, for example using an adenosine triphosphate (ATP) based assay. The system includes a device that is use in combination with single-use or disposable cartridges. The cartridge receives the water sample and is pre-loaded with one or more reagents. The device receives the cartridge and contains physical, electronic and/or mechatronic devices that interact with cartridge. One or more actions such as metering, mixing and conveying are performed automatically by elements of the device and/or cartridge. A sensor in the device measures light produced in the cartridge from a reaction with ATP in the water sample. Optionally, the cartridge also contains a pre-loaded amount of ATP, which is used to provide an internal reference or calibration measurement.

Abstract: The present disclosure relates to a protective mask to deactivate damaging agents. In some examples, the mask includes a filter element that traps particles of the damaging agent. A sanitizing emitter permeates the filter element with a sanitizing agent to deactivate the damaging agent. In some examples, the sanitizing agent is ultraviolet light configured to deactivate a virus such as SARS-CoV-2.

Abstract: Methods of applying an inorganic material to a metal substrate that includes a metallic material having an austenite transformation temperature. The method includes depositing inorganic particles onto a surface of the metal substrate. In some embodiments, methods may include depositing inorganic particles at a deposition temperature that does not cause the metallic material to exceed the austenite transformation temperature. The inorganic particles deposited onto the surface of the metal substrate may form an abrasion-resistant coating on the surface of the metal substrate. The difference between the coefficient of thermal expansion of the metallic material and the coefficient of thermal expansion of the abrasion-resistant coating may be 10×10?6/degrees C. or less.

Abstract: A method of manufacturing a bottom bearing may include forming a first half-cylinder and a second half-cylinder, the first half-cylinder including a first shoulder and a first inside surface and the second half-cylinder including a second shoulder and a second inside surface. The first shoulder and second shoulder are configured to bear the weight of a vertical shaft by exerting an upward force on a sleeve in mechanical communication with the vertical shaft.

Abstract: Techniques are described for providing access to anonymized user data derived from external data providers. A persona management system generates a searchable data store containing metadata related to a plurality of users of the persona management system. The metadata includes entries indicating: a first identifier of a user of the plurality of users of the persona management system, a second identifier of an external data provider of a plurality of external data providers that possess data related to users of the persona management system, a third identifier of an algorithm that is used to transform data possessed by the external data provider related to the user of the persona management system into one or more transformed data values, and the one or more transformed data values. In response to requests from various data consumers, the persona management system uses the metadata to identify users matching specified search criteria.

Abstract: A method of predicting an adverse event in a patient having an implantable blood pump including correlating a pulsatility value to a flow trough value associated with the blood pump to determine a flow peak value; dividing the determined flow peak value by a pump current to determine a pulsatility peak value; tracking a first moving average of the pulsatility peak value, the first moving average defining a threshold range; tracking a second moving average of the pulsatility peak value, the second moving average being faster than the first moving average; and generating an alert when the second moving average deviates from the threshold range.

Abstract: A method of forming a cast component and a method of forming a casting mold. The method is performed by connecting at least one wax gate component to a ceramic core-shell mold. The ceramic core-shell mold includes at least a first core portion, a first shell portion, and a second shell portion, wherein the first shell portion is adapted to interface with at least the second shell portion to form at least one first cavity between the core portion and the first and second shell portions. The core-shell mold may be inspected and assembled prior to connection of the wax gate component. At least a portion of the ceramic core-shell mold and the wax gate component is coated with a second ceramic material. The wax gate component is then removed to form a second cavity in fluid communication with the first cavity.

Abstract: Cleaning fixtures for a component(s) are disclosed. The cleaning fixtures may include a first and second component recess configured to receive a first and second component, respectively. Each component recess may be defined between a first and second member of the cleaning fixture. The cleaning fixture may also include a first solvent conduit in fluid communication with the first component recess, and a second solvent conduit in fluid communication with the second component recess. The first and second solvent conduit may include physical characteristic(s) configured to control delivery of solvent into the respective component recess at desired fluid parameter(s). The cleaning fixture may also include a first gas conduit in fluid communication with the first component recess, and a second gas conduit in fluid communication with the second component recess. Each of the first and second gas conduit may deliver a pressurized gas to the respective component recess.

Abstract: A method of forming a cast component and a method of forming a casting mold. The method is performed by connecting at least one wax gate component to a ceramic core-shell mold. The ceramic core-shell mold includes at least a filter, first core portion, a first shell portion, and at least one first cavity between the core portion and the first shell portion. The core-shell mold may be manufactured using an additive manufacturing process and may include an integrated ceramic filter. At least a portion of the ceramic core-shell mold and the wax gate component is coated with a second ceramic material. The wax gate component is then removed to form a second cavity in fluid communication with the first cavity.

Abstract: A cleaning nozzle includes an inner nozzle housing having a feed passage for carrying cleaning fluid, a plurality of nozzle tips that each define a discharge opening in fluid communication with the feed passage, and an outer nozzle housing received over the inner nozzle housing. The outer nozzle housing includes a plurality of outer nozzle extensions that each extend over one of the nozzle tips. The outer nozzle extensions can be inserted into ports of an adapter, and flow of the cleaning fluid through the nozzle is split between the nozzle tips so that multiple optical connectors that populate the adapter can be cleaned simultaneously in a substantially uniform manner.

Abstract: An imaging station includes a rotating pedestal, a camera mover, multiple light sources, and back lit screens. It also includes a computer with all of the software to control the imaging station. The output of the imaging station is a set of images of an object that represents a subset of the ideal set, which can be used to train an object detector.

Abstract: The device disclosed within as a reusable fuel pump handle guard. A user holds the handle guard in his or her hand, with his palm against the grip, and fingers extending down the two parallel elements. He then applies the hand guard to the hand rest of the fuel pump. A shoulder located at the front edge of the grip prevents the user's hand from sliding too far forward and off the handle guard. The flexible material of the handle guard allows the user to bend the receiving element toward the latching element, around the grip of the gas pump, and underneath the handle of the gas pump actuating the pump ultimately passing the hook of the latching element into the hole of the receiving element.

Abstract: A method for separating a parent isotope from a daughter isotope is provided, the method comprising supplying irradiated target; dissolving the irradiated target; treating the dissolved irradiated target to a precipitation step to form a first solid phase of the parent isotope and a first liquid phase of the daughter isotope; filtering the first liquid phase of daughter isotope to create a first purified fraction of the daughter isotope to create a second solid phase of the parent isotope and a second liquid phase of the daughter isotope; and filtering the second liquid phase to create a second liquid fraction of the daughter isotope. The process can be repeated until the 99Mo is exhausted and the enriched target material 98Mo or 100Mo can be easily re-used.

Abstract: Systems and methods for providing federated power management in an electronic circuit. The methods comprise: performing first operations by a processing device to obtain information indicating a current level of charge for each of a plurality of capacitors which have been supplied energy from a power source; transforming, by the processing device, each capacitor's current level of charge into a number of service units for a respective electronic load device of a plurality of electronic load devices; determining, by the processing device, at least one of recharging priorities for the plurality of capacitors and discharging priorities for the plurality of capacitors at least based on the results of said transforming; and performing second operations by the processing device to cause the plurality of capacitors to be recharged in accordance with the recharging priorities or discharged in accordance with the discharging priorities.