Abstract: The present disclosure provides the methods for making 4-[4-cyano-2-({[(2?R,4S)-6-(isopropylcarbamoyl)-2,3-dihydrospiro[chromene-4,1?-cyclopropan]-2?-yl]carbonyl}amino)phenyl]butanoic acid. The present disclosure also generally relates to intermediates useful in the said methods.

Abstract: A LIDAR unit includes a housing defining a cavity. The LIDAR unit further include a plurality of emitters disposed on a circuit board within the cavity. Each of the emitters emits a laser beam along a transmit path. The LIDAR system further includes a first telecentric lens assembly positioned within the cavity and along the transmit path such that the laser beam emitted from each of the plurality of emitters passes through the first telecentric lens assembly. The LIDAR further includes a second telecentric lens assembly positioned within the cavity and along a receive path such that a plurality of reflected laser beams entering the cavity pass through the second telecentric lens assembly. The first telecentric lens assembly and the second telecentric lens assembly each include a field flattening lens and at least one other lens.

Abstract: A fugitive gas detection system is provided. The system includes a cloud service, a plurality of reach-based components, a plurality of wireless gas sensors. The reach-based components comprise backhauls and gateways. The wireless gas sensors are acted as nodes to acquire sensor data in a local mesh network and the nodes are connected to the cloud service through the reach-based components, one node can transmit the sensor data to other sensor nodes of the local mesh network. The system measures flammable gas levels with speed, economy and accuracy.

Abstract: The invention relates to a splint for an infant. It has a body including an insert of a malleable material, wherein the body has a longitudinal axis, a first arm extending from an edge of the body in a plane substantially perpendicular to the longitudinal axis; and a second arm, spaced apart from the first arm, extending from the edge of the body in a plane substantially perpendicular to the longitudinal axis. The arms wrap around the limb of the infant and provide a surface for using medical tape or the like, thus avoiding the need for the tape to come into contact with the skin of the infant. In addition, the malleable insert allows the splint to be deformed and hold its shape if the splint is to be used on a joint of the limb.

Abstract: A LIDAR system includes a plurality of LIDAR units. Each of the LIDAR units includes a housing defining a cavity. Each of the LIDAR units further includes a plurality of emitters disposed within the cavity. Each of the plurality of emitters is configured to emit a laser beam. The LIDAR system includes a rotating mirror and a retarder. The retarder is configurable in at least a first mode and a second mode to control a polarization state of a plurality of laser beams emitted from each of the plurality of LIDAR units. The LIDAR system includes a polarizing beam splitter positioned relative to the retarder such that the polarizing beam splitter receives a plurality of laser beams exiting the retarder. The polarizing beam is configured to transmit or reflect the plurality of laser beams exiting the retarder based on the polarization state of the laser beams exiting the retarder.

Abstract: A LIDAR assembly is provided. The LIDAR assembly includes a LIDAR unit. The LIDAR unit includes a housing defining a cavity. The LIDAR unit further includes a plurality of emitters disposed within the cavity. Each of the plurality of emitters is configured to emit a laser beam. The LIDAR assembly further includes a switchable mirror. The switchable mirror is positioned relative to the LIDAR unit such that the switchable mirror receives a plurality of laser beams exiting the housing of the LIDAR unit. The switchable mirror is configurable in at least a reflective state to direct the plurality of laser beams along a first path and a transmissive state to direct the plurality of laser beams along a second path that is different than the first path to widen a field of view of the LIDAR unit along a first axis.

Abstract: A vehicle lamp assembly includes a light source that emits light, a side marker lamp having a lens, and a frustum reflector that guides light from the light source to the lens of the side marker lamp. A vehicle lighting method includes emitting light from a light source into a frustum reflector, redirecting the light within the frustum reflector, and illuminating a side marker lamp using the light redirected within the frustum reflector.

Abstract: Methods, systems and devices for evaluating incoming air to an engine, industrial controller including engine controls, valves and solenoids, for concentrations of explosive or combustible gases or vapors, and actuating process control including but not limited to shutting down an engine or other industrial process to control an outcome including the prevention of an overspeed condition when pre-set or calculated elevated gas or vapor concentrations are detected. In some embodiments industrial control including engine shutdown may be achieved conventionally via an electronic kill signal, a shutdown of the fuel injector, carburetor or fuel pump, and in emergency conditions by the shutoff of incoming air to an air intake, turbocharger, or other air delivery systems. Decisions based on explosive gas or vapor concentrations and species and the use of networking to allow additional systems to take action before explosive gases or vapors reach said other valve-sensor devices can provide additional safety.

Abstract: A LIDAR assembly is provided. The LIDAR assembly includes a LIDAR unit. The LIDAR unit includes a housing defining a cavity. The LIDAR unit further includes a plurality of emitters disposed within the cavity. Each of the plurality of emitters is configured to emit a laser beam. The LIDAR assembly further includes a switchable mirror. The switchable mirror is positioned relative to the LIDAR unit such that the switchable mirror receives a plurality of laser beams exiting the housing of the LIDAR unit. The switchable mirror is configurable in at least a reflective state to direct the plurality of laser beams along a first path and a transmissive state to direct the plurality of laser beams along a second path that is different than the first path to widen a field of view of the LIDAR unit along a first axis.

Abstract: A LIDAR assembly defining a horizontal axis and a vertical axis is provided. The LIDAR assembly includes a LIDAR unit. The LIDAR unit includes a housing defining a cavity. The LIDAR unit further includes a first plurality of emitters disposed within the cavity and a second plurality of emitters disposed within the cavity. Each of the first plurality of emitters is configured to emit a first laser beam at a first wavelength. Conversely, each of the second plurality of emitters is configured to emit a second laser beam at a second wavelength that is different than the first wavelength. The LIDAR assembly includes an optic positioned outside of the housing. The optic is configured to optically act on the first laser beam and the second laser beam in a different manner to widen a field of view of the LIDAR unit along the vertical axis.

Abstract: A veterinary saw assembly having a tool coupler for coupling to an external power tool and a drive coupler for driving a cutting string from the power tool. The cutting string can be an abrasive wire. The power tool can be a drill. The saw assembly can be used for dehorning or foetotomy procedures. Also disclosed are saws that include the saw assembly, cutting strings for use with the saw assembly, methods of stringing the saw assembly with a cutting string, and a kit including the cutting string and instructions for its use.

Abstract: A LIDAR system includes a first prism disk rotatable about a first axis at a first rotational speed; a first LIDAR unit having a first plurality of emitters to emit a first plurality of laser beams which pass through the first prism disk to produce a first plurality of refracted laser beams; a second prism disk rotatable about a second axis at a second rotational speed; a second LIDAR unit having a second plurality of emitters to emit a second plurality of laser beams which pass through the second prism disk to produce a second plurality of refracted laser beams; and an optic rotatable about a third axis at a third rotational speed that is faster than at least one of the first rotational speed or the second rotational speed. The optic reflects the first plurality of refracted laser beams and reflects the second plurality of refracted laser beams.

Abstract: A solid-state optical system comprising: a sensor array having a field of view; an emitter array comprising a plurality of emitter units mounted on a surface of a common substrate and arranged in a two-dimensional array, wherein each emitter unit in the plurality of emitter units is spaced apart from its adjacent emitter units by a first distance and emits pulses of light having a predetermined beam divergence; an optical element comprising a plurality of lenses corresponding in number to the plurality of emitter units and arranged in a two-dimensional array in which adjacent optical elements in the two-dimensional array are spaced apart from each other by the first distance, wherein the optical element is positioned adjacent to the emitter array such that each lens in the plurality of lenses is spaced apart from and receives the pulses of light emitted from a corresponding one of the emitter units in the plurality of emitter units and is configured to reduce the angle of divergence of the pulses of light emi

Abstract: Panels of biomarkers, methods and systems are disclosed for determining gene expression, and diagnosing and treating melanoma.

Abstract: A gas sensor system includes at least one gas sensor configured to receive at least one gas to be sampled; a processor configured to implement computer executable instructions; a first output interface in communication with the processor; and a computer memory in communication with the processor. A method includes measuring a density of the at least one gas; at least one of a) heating and b) cooling the at least one gas with a first thermal input; determining a first rate at which the at least one gas changes temperature when at least one of a) heating and b) cooling the at least one gas; comparing at least one of the density and the first rate to a reference database of gases; and determining at least one of a) a category b) a lower explosive limit and c) a concentration of the at least one gas.

Abstract: Embodiments of the present disclosure include techniques for managing dirty data. An agent receives a request for data. If the data is dirty data, the agent may use a replacement policy to determine if the data should be passed clean or dirty to the requestor. The replacement policy may correspond to how long the dirty data being stored in a cache line is to be maintained. In one embodiment, the replacement policy is a circuit, such as an SRAM and a logic circuit, for example.

Abstract: A LIDAR system includes a LIDAR unit. The LIDAR unit includes a housing defining a cavity. The LIDAR unit further include a plurality of emitters disposed on a circuit board within the cavity. Each of the emitters emits a laser beam along a transmit path. The LIDAR system further includes a first optic rotatable about a first axis at a first rotational speed and a second optic rotatable about a second axis at a second rotational speed that is faster than the first rotational speed. The first optic is positioned relative to the LIDAR unit such that a plurality of laser beams exiting the LIDAR unit pass through the first optic. The second optic is positioned relative to the first optic such that each of a plurality of refracted laser beams exiting the prism disk reflect off of the second optic.

Abstract: A gas sensor system includes at least one gas sensor configured to receive at least one gas to be sampled; a processor configured to implement computer executable instructions; a first output interface in communication with the processor; and a computer memory in communication with the processor. A method includes measuring a density of the at least one gas; at least one of a) heating and b) cooling the at least one gas with a first thermal input; determining a first rate at which the at least one gas changes temperature when at least one of a) heating and b) cooling the at least one gas; comparing at least one of the density and the first rate to a reference database of gases; and determining at least one of a) a category b) a lower explosive limit and c) a concentration of the at least one gas.

Abstract: In one embodiment, systems and methods include using an automated laser system to remove a portion of a coating for nutplate installation. An automated laser system comprises a laser scanner and a laser head, wherein the laser head is coupled to the laser scanner. The laser head comprises a containment unit and a vacuum connector wherein the vacuum connector is disposed on a first side of the containment unit. The laser head further comprises a camera system, a light source, a first actuator, and a second actuator all disposed on a top surface of the containment unit. The laser head further comprises an end piece, wherein the second actuator is configured to displace the end piece.