Abstract: Devices for controlling the capture, trapping, and transport of macromolecules include at least one fluidic transport nanochannel that intersects and is in fluid communication with at least one transverse nanochannel with (shallow) regions and/or with integrated transverse electrodes that enable fine control of molecule transport dynamics and facilitates analyses of interest, e.g., molecular identification, length determination, localized (probe) mapping and the like.

Abstract: Devices, such as chips for DNA analysis, have at least one fluid transport nanochannel with at least one intersecting (e.g., transverse) sensing nanochannel that can be monitored for change in ionic current to determine characteristics or parameters of interest, e.g., molecular identification, length determination, localized (probe) mapping and the like.

Abstract: Techniques for providing feed-based case management on an online social network. A user interface that includes a publisher and an information feed is provided. Information associated with a record is received and the record is updated in a database system. A feed item associated with the database system update is generated and provided in the information feed. The feed item includes one or more actionable selections providing a reference to the publisher. Selection of one of the one or more actionable selections causes the publisher to be operable to receive further information associated with the record. The record is capable of being updated based on the further information. In some implementations, the record is a case and the user interface serves as a single interface for all interactions required in solving the case.

Abstract: Microchips which are particularly suitable for use with a mass spectrometer include a microchip body with at least one fluid channel formed into the microchip body and at least two flat monolithic closely spaced integrated ESI (electrospray ionization) emitters defined by shaped projections formed to extend from one side of the microchip body, a respective one being in fluid communication with a fluid channel. Related systems and methods are also described.

Abstract: Techniques for providing feed-based case management on an online social network. A user interface that includes a publisher and an information feed is provided. Information associated with a record is received and the record is updated in a database system. A feed item associated with the database system update is generated and provided in the information feed. The feed item includes one or more actionable selections providing a reference to the publisher. Selection of one of the one or more actionable selections causes the publisher to be operable to receive further information associated with the record. The record is capable of being updated based on the further information. In some implementations, the record is a case and the user interface serves as a single interface for all interactions required in solving the case.

Abstract: A well access line monitor. The monitor may be employed to directly interface and establish the current yield strength of a plastically deformable line such as coiled tubing or slickline. Such interfacing may take place in advance of, or during an application. Thus, the fitness of the line for the application may be established in real-time. Further, with comparison to a reference log of projected yield strength for the line over the course of multiple bend cycles, the remaining life of the line may also be established.

Abstract: An applier for ligation clip is provided. The applier includes: an outer tube having mounting bosses; a pair of jaws pivotally connected to the mounting bosses, the jaws having actuating projections; a feed tube located in the outer tube and configured to move axially within the outer tube, the feed tube having actuating slots in which the actuating projections are located; a clip lock arm located in the outer tube and configured to move axially within the outer tube; and a clip advance arm located in the outer tube and configured to move axially within the outer tube, the clip advance arm having flexible pinchers at one end of the clip advance arm. A method of applying a ligation clip is also disclosed.

Abstract: A narrow profile surgical ligation clip has two legs with clamping surfaces joined by a hinge near the proximal ends, allowing the clip to reversibly open and close. A locking mechanism is proximal to the hinge to bias or lock the clip closed, including first and second jaw structures spaced on opposite sides of a longitudinal axis of the clip thereby defining a locking space therebetween. In one embodiment, a wedge or buttress body moves by application of an external force applied to a proximal end of the clip towards the hinge to move into the locking space such that one or more outer surfaces or projections of portions of the body fit into or abut against complementary surfaces or other parts of the locking mechanism or clip assembly to bias or lock the clip in a closed position and provide additional closing force to the inner clamping surfaces.

Abstract: Systems and methods are provided for dynamic list views and detail pages. A database system can update a subscribed field in a data record when the field is updated and when a user interface is displaying the field in a list view. The system can provide a notification of an update for a subscribed field in a data record when the field is updated and when a user interface is displaying the field in a list view. The system can update a subscribed field in a data record when the field is updated and when a user interface is displaying the field in a detail page for a list view. The system can provide a notification of an update for a subscribed field in a data record when the field is updated and when a user interface is displaying the field in a detail page for a list view.

Abstract: A coiled tubing connection system is used in a well. A connector having an engagement end is used to couple a wellbore device to the end of a coiled tubing. The connector is spoolable, and the engagement end comprises engagement features that facilitate formation of a connection that is dependable and less susceptible to separation.

Abstract: Methods of forming at least one nanochannel include: (a) providing a substrate having a thick single or a thick multi-layer overlayer; (b) milling at least one channel through the overlayer into the substrate; then (c) removing the overlayer; and (d) forming at least one nanochannel in the substrate having an average width and depth dimension that is less than about 10 nm in response to the milling and removing steps.

Abstract: Techniques for providing feed-based case management on an online social network. A user interface that includes a publisher and an information feed is provided. Information associated with a record is received and the record is updated in a database system. A feed item associated with the database system update is generated and provided in the information feed. The feed item includes one or more actionable selections providing a reference to the publisher. Selection of one of the one or more actionable selections causes the publisher to be operable to receive further information associated with the record. The record is capable of being updated based on the further information. In some implementations, the record is a case and the user interface serves as a single interface for all interactions required in solving the case.

Abstract: A method of presenting information associated with an application begins by providing a graphical user interface (GUI) for display at a user device. The GUI includes a primary GUI element and a secondary GUI element. The content of the primary GUI element is contextually related to the content of the secondary GUI element. The method continues by detecting changes made to the primary content resulting from user interaction with the primary GUI element, and, in response to detecting the changes, refreshing the secondary GUI element to update the secondary content.

Abstract: An information handling system (IHS) is disclosed providing a power supply operable to provide an output current to the IHS during power initiation. The IHS may also include a first power component associated with a first power stage wherein the first power stage may have a first current threshold. Furthermore, the IHS may include a power control logic coupled to the power supply and the first power component. As such, the power control logic may be operable to communicate the first power stage to the power supply, and if the output current does not exceed the first current threshold during the first power stage, the power control logic may be operable to communicate a second power stage having a second current threshold to the power supply.

Abstract: A method for conducting a broad range of biochemical analyses or manipulations on a series of nano- to subnanoliter reaction volumes and an apparatus for carrying out the same are disclosed. The invention is implemented on a fluidic microchip to provide high serial throughput. In particular, the disclosed device is a microfabricated channel device that can manipulate nanoliter or subnanoliter reaction volumes in a controlled manner to produce results at rates of 1 to 10 Hz per channel. The reaction volumes are manipulated in serial fashion analogous to a digital shift register. The invention has application to such problems as screening molecular or cellular targets using single beads from split-synthesis combinatorial libraries, screening single cells for RNA or protein expression, genetic diagnostic screening at the single cell level, or performing single cell signal transduction studies.

Abstract: Electrically heated pumps are disclosed that include electric heating elements that are linked to a process controller. In a magnetic drive pump, the external jacketing on the pump head, pressure relief valve and casing can be replaced with electric heating elements attached to the pump through the use of adhesive or mechanical fastening devices. For the bracket portion of the magnetic drive pump, the external jacketing can be removed and the heating element is attached to the canister that contains the liquid and that is located between the inner and outer magnetic drive assemblies. Through the use of appropriately placed thermocouples in the head, pressure relief valve, casing, bracket, canister, etc., and a single or multi-channel on/off, proportional or PID controller, the heating zones may be linked together, monitored and controlled to the application requirements. The disclosed pump designs may also be applied to auxiliary equipment such as strainers.

Abstract: An embodiment of a clamping, cutting, and wiping assembly assembly may comprise a frame defining a pathway for a cable to pass therethrough, a clamp mechanism, a cutter device, and a wiper mounted to the frame adjacent the pathway for engaging with a cable, wherein the clamp device, the cutter, and the wiper may each be actuatable.

Abstract: A microfabricated device employing a bridging membrane and methods for electrokinetic transport of a liquid phase biological or chemical material using the same are described. The bridging membrane is deployed in or adjacent to a microchannel and permits either ionic current flow or the transport of gas species, while inhibiting the bulk flow of material. The use of bridging membranes in accordance with this invention is applicable to a variety of processes, including electrokinetically induced pressure flow in a region of a microchannel that is not influenced by an electric field, sample concentration enhancement and injection, as well as improving the analysis of materials where it is desired to eliminate electrophoretic bias. Other applications of the bridging membranes according to this invention include the separation of species from a sample material, valving of fluids in a microchannel network, mixing of different materials in a microchannel, and the pumping of fluids.

Abstract: A system and method for managing entitlements in a multi-tenant database system. In one embodiment, a method includes receiving service level definitions for one or more entitlements, and maintaining the one or more entitlements. The method further includes verifying if one or more users are eligible for the one or more entitlements, and enforcing the one or more entitlements based on the service level definitions.

Abstract: A system and method for providing administrative capabilities in a multi-tenant database system. In one embodiment, a method includes providing a portal for a database system to a user, providing administrative capabilities through the portal, and enabling the user to manage objects in the database system using the administrative capabilities.