Abstract: A construction hanger having two nested clamping frames that slide relative to each other in a disengaged condition to selectively define a throat distance between two stop edges provided by the two nested clamping frames, respectively. An engageable fastener enables a user to set and secure a desired throat distance by way of an engageable fastener that directly connects the two nested clamping frames in an engaged condition. A rod nut may be sandwiched between the two nested clamping frames so that a threaded rod can engage and thereby move the construction hanger to a desired location along a joist or beam.

Abstract: A portable system for cooling which includes a Peltier thermoelectric cooler coupled to the garment and utilitarian apparatuses, including wheelchairs, child carriers, and military equipment. The thermoelectric cooler comprises a cold side plate and a hot side plate. The cooling device further comprises a thermal shield. The thermal shield comprises a thermally reflective surface and a thermal conduction sheet coupled to the cold side of the thermoelectric cooler. The portable cooling device further comprises a cold pack thermally coupled to a side of the thermal conduction sheet. The portable cooling device comprises a blower configured to blow air across the hot side of the thermoelectric cooler.

Abstract: This invention pertains to mutant Cas9 nucleic acids and proteins for use in CRISPR/Cas endonuclease systems, and their methods of use. In particular, the invention pertains to an isolated mutant Cas9 protein, wherein the isolated mutant Cas9 protein is active in a CRISPR/Cas endonuclease system, wherein the CRISPR/Cas endonuclease system displays reduced off-target editing activity and maintained on-target editing activity relative to a wild-type CRISPR/Cas endonuclease system. The invention also includes isolated nucleic acids encoding mutant Cas9 proteins, ribonucleoprotein complexes and CRSPR/Cas endonuclease systems having mutant Cas9 proteins that display reduced off-target editing activity and maintained on-target editing activity relative to a wild-type CRISPR/Cas endonuclease system.

Abstract: A composite mattress includes a pressurizable layer and a top layer. A coiled spring layer may also be included in the composite mattress. The composite mattress may also include a base layer and/or an intermediate layer. A foundation, or rail, may laterally surround the pressurizable layer and the top layer. The composite mattress may include a cover, including a base panel, a periphery, and a top panel. The cover may encase the other components of the composite mattress. The composite mattress may include a separable top and bottom; these elements may be modular, enabling individuals or couples customize a mattress by selecting one or more tops from a plurality of available for use with one or more bases from a plurality of available bases.

Abstract: Various embodiments include a parallel processing computer system that provides multiple memory synchronization domains in a single parallel processor to reduce unneeded synchronization operations. During execution, one execution kernel may synchronize with one or more other execution kernels by processing outstanding memory references. The parallel processor tracks memory references for each domain to each portion of local and remote memory. During synchronization, the processor synchronizes the memory references for a specific domain while refraining from synchronizing memory references for other domains. As a result, synchronization operations between kernels complete in a reduced amount of time relative to prior approaches.

Abstract: An apparatus and method for radiation measurement are used to determine clearance of a rotating gas turbine component. The apparatus includes a probe body on a stationary component outward of the rotating component and a pair of sensor assemblies coupled to the probe body. Each sensor assembly includes a plurality of prisms coupled to the probe body Each prism of the plurality of prisms has a distinct angular orientation to direct radiation from the focusing lens to the rotating component surface off-axis with respect to an axis of the respective radiation source of the pair of radiation sources and with less directional variation than radiation from the respective radiation source.

Abstract: This invention pertains to mutant Cas9 nucleic acids and proteins for use in CRISPR/Cas endonuclease systems, and their methods of use. In particular, the invention pertains to an isolated mutant Cas9 protein, wherein the isolated mutant Cas9 protein is active in a CRISPR/Cas endonuclease system, wherein the CRISPR/Cas endonuclease system displays reduced off-target editing activity and maintained on-target editing activity relative to a wild-type CRISPR/Cas endonuclease system. The invention also includes isolated nucleic acids encoding mutant Cas9 proteins, ribonucleoprotein complexes and CRSPR/Cas endonuclease systems having mutant Cas9 proteins that display reduced off-target editing activity and maintained on-target editing activity relative to a wild-type CRISPR/Cas endonuclease system.

Abstract: This invention pertains to mutant Lachnospiraceae bacterium ND2006 (Lb) Cas12a nucleic acids and proteins for use in CRISPR/Cas12a endonuclease systems, and their methods of use. In particular, the invention pertains to an isolated mutant LbCas12a protein, wherein the isolated mutant LbCas12a protein is active in a CRISPR/Cas12a endonuclease system. The invention also includes isolated nucleic acids encoding mutant LbCas12a proteins, ribonucleoprotein complexes and CRISPR/Cas12a endonuclease systems having mutant LbCas12a proteins.

Abstract: A fabrication method of a semiconductor device is described. Generally, the method includes forming a customizable oxide-nitride-oxide (ONO) stack over a substrate in an in-situ atomic layer deposition (ALD) tool or chamber. Radical oxidation or oxide deposition process steps are performed to form tunnel dielectric layer overlying the substrate. Silicon nitride deposition process steps are also performed to form a multi-layer charge trapping (CT) layer in which at least some of the process parameters of silicon nitride deposition process steps are adjusted when forming the first and second CT sub-layers of the multi-layer CT layer. Subsequently, radical oxidation or oxide deposition process steps are performed in the ALD tool to form a blocking dielectric layer overlying the multi-layer CT layer.

Abstract: A force sensing system for determining if a user input has occurred, the system comprising: an input channel, to receive an input from at least one force sensor; an activity detection stage, to monitor an activity level of the input from the at least one force sensor and, responsive to an activity level which may be indicative of a user input being reached, to generate an indication that an activity has occurred at the force sensor; and an event detection stage to receive said indication, and to determine if a user input has occurred based on the received input from the at least one force sensor.

Abstract: A high-low shifting active torque management continuously variable transmission (CVT) system is provided. A primary pulley of a CVT is in operational communication with an engine. A high variable torque limiting clutch and a low variable torque limiting clutch selectively couple torque between a secondary pulley of the CVT and at least one drive axle of a vehicle when the vehicle when respectfully activated. The high variable torque limiting clutch and the low variable torque limiting clutch are configured to dynamically adjust a respective slippage threshold to above a then current output torque of the CVT and below a then current clamping force generated by the primary pulley and the secondary pulley on a torque connecting endless looped member of the CVT when respectfully activated.

Abstract: Radiation emitted by a radiation source along a projected path can be diverted by a divergence angle by a lens in the projected path with a first surface and a second surface spaced apart along the projected path with the second surface farther from the radiation source than the first surface. The first surface can be curved and have a normal point perpendicular to a line parallel to the projected path and offset from the projected path by an eccentricity. Radiation striking the first surface can be diverted by a first angle relative to the projected path and can continue to strike the second surface, which diverts the radiation by a second angle. The sum of the first and second angles is the divergence angle. The apparatus can be used in a probe assembly to determine tip clearance of a turbine blade during operation of a gas turbine engine.

Abstract: This invention pertains to optimized protein fusion linkers for creating multi-functional chimeric proteins and methods of using the same. Additionally, the invention pertains to chimeric proteins for use in guided endonuclease systems and methods of using the same.

Abstract: A carbazate-functional compound includes a plurality of groups having the following structure: [formula (I)] where X forms at least a portion of: a urethane linkage, an ester linkage, or an ether linkage. At least one R1 from the plurality of groups is free of a hydroxyl-functional group.

Abstract: A carrier such as a belt bag, shoulder bag, or backpack is provided with a lid that reversibly secures an opening in the walls of the carrier at a top end of the carrier using paired and attracting magnets mounted in stiffening strips located along edges of the lids and along the edges of the openings in the carrier.

Abstract: This invention pertains to mutant Cas9 nucleic acids and proteins for use in CRISPR/Cas endonuclease systems, and their methods of use. In particular, the invention pertains to an isolated mutant Cas9 protein, wherein the isolated mutant Cas9 protein is active in a CRISPR/Cas endonuclease system, wherein the CRISPR/Cas endonuclease system displays reduced off-target editing activity and maintained on-target editing activity relative to a wild-type CRISPR/Cas endonuclease system. The invention also includes isolated nucleic acids encoding mutant Cas9 proteins, ribonucleoprotein complexes and CRSPR/Cas endonuclease systems having mutant Cas9 proteins that display reduced off-target editing activity and maintained on-target editing activity relative to a wild-type CRISPR/Cas endonuclease system.

Abstract: This invention pertains to mutant Lachnospiraceae bacterium ND2006 (Lb) Cas12a nucleic acids and proteins for use in CRISPR/Cas12a endonuclease systems, and their methods of use. In particular, the invention pertains to an isolated mutant LbCas12a protein, wherein the isolated mutant LbCas12a protein is active in a CRISPR/Cas12a endonuclease system. The invention also includes isolated nucleic acids encoding mutant LbCas12a proteins, ribonucleoprotein complexes and CRISPR/Cas12a endonuclease systems having mutant LbCas12a proteins.

Abstract: An actuator-controlled electric strike for operating in conjunction with a latch and deadbolt of a lockset. The strike comprises a housing, keeper, and deadbolt bracket. The housing includes a longitudinal length, a back wall extending along the longitudinal length, and side walls defining an entry chamber. The keeper is disposed in the entry chamber about an axis of rotation parallel with the back wall. The keeper is rotatable about the axis of rotation between locked and unlocked positions. The back wall is disposed opposite the keeper when the keeper is in the locked position. The deadbolt bracket is adjustably positioned in the entry chamber along the housing longitudinal length, wherein the deadbolt bracket includes a first wall, a second wall, and a bracket side wall connecting the first wall and the second wall. The deadbolt bracket defines at least a portion of a deadbolt receiving chamber for the deadbolt.

Abstract: Systems and methods to process a plurality of information simultaneously to generate outputs are disclosed. Exemplary implementations may: execute individual instances of an executable program for individual information sources such that a first engine instance of a rules engine is executed for a first information source; establish communication between electronic storage and the first engine instance via a transceiver that enables communication between the electronic storage, information sources, one or more processors, and/or external resources such that import of the atomic rules, the business rules, and/or one or more specialized rules to the first engine instance is enabled; and establish communication between the first information source and the first engine instance via the transceiver so that individual information objects from the first information source are received by the first engine instance in an ongoing manner.

Abstract: A pipe repair stent includes a gasket defining a first gasket end, a second gasket end opposite the first gasket end, an outer gasket surface, and an inner gasket surface, the inner gasket surface defining a main passage, a stent axis extending centrally through the main passage, the outer gasket surface at least partially defining an outer stent surface of the pipe repair stent; a first pipe engagement strip coupled to and extending circumferentially along the outer stent surface proximate to the first gasket end; and a second pipe engagement strip coupled to and extending circumferentially along the outer stent surface proximate to the second gasket end; wherein each of the first and second pipe engagement strips extend radially outward beyond the outer stent surface and are configured to engage an inner wall of a pipe to improve a grip of the pipe repair stent on the inner wall.