Abstract: Techniques and devices are disclosed for fabrication workstation and assembly layout device. The fabrication workstation includes a table with a work surface. The work surface being a continuous surface and configured to support a plurality of components for fabrication of an assembly, such as an assembly of metal components. The device further includes a beam located above the work surface. The beam is operatively coupled to the table, such that the beam moves relative to the work surface in a first direction. A marking device on the beam is configured to move along the beam in a second direction different from the first direction. The marking device is further configured to mark the work surface in the shape of an assembly pattern. Assembly components are positioned on the assembly pattern to be assembled.

Abstract: In one aspect, an additive manufacturing system is provided. The additive manufacturing system includes a build platform, a first plurality of particles positioned on the build platform, and a particle containment system positioned on the build platform. The particle containment system includes a particle containment wall. The particle containment wall at least partially surrounds the first plurality of particles and includes a second plurality of particles consolidated together. The particle containment wall includes a top end spaced apart from the build platform, an inner face positioned against the first plurality of particles and extending between the build platform and the top end, and an outer face that faces a substantially particle-free region, the outer face positioned opposite the inner face and extending between the build platform and the top end.

Abstract: A restraint apparatus for securing a mobility device in a vehicle includes a base configured to being mounted to a floor of the vehicle, a support coupled to the base and extending upward therefrom, and a backing plate adjustably coupled to the support. The backing plate defines a channel to provide vertical adjustment of the backing plate with respect to the support. An upper support is pivotally coupled to the backing plate, and a claw assembly is coupled to the upper support. The claw assembly includes a claw member and a latching member, where the latching member is pivotally coupled to the claw member to enable pivotal movement between an unlatched position and a latched position. A control system operably controls the pivotal movement of the latching member between its latched position to its unlatched positions. In the unlatched position, the claw assembly provides an opening for receiving the device.

Abstract: Example methods, apparatus, systems and articles of manufacture (e.g., physical storage media) to deduplicate common devices across multiple data sources are disclosed. An example apparatus includes instructions to identify a first device in a first data source and a second device in a second data source as a possible common device, calculate at least one of a station duration metric, a time match metric or a station path metric, the station duration metric, the time match metric based times of day that the first device tuned to a second set of stations and times of day that the second device tuned to the second set of stations, determine a score based on the at least one of the station duration metric, the time match metric, or the station path metric, and determine when the first device and the second device are a common device based on the score.

Abstract: A prosthetic heart valve can include an outer support assembly, an inner valve assembly, which define between them an annular space, and a pocket closure that bounds the annular space to form a pocket in which thrombus can be formed and retained. Alternatively, or additionally, the outer support assembly and the inner valve assembly can be coupled at the ventricle ends of the outer support assembly and the inner valve assembly, with the outer support assembly being relatively more compliant in hoop compression in a central, annulus portion than at the ventricle end, so that the prosthetic valve can seat securely in the annulus while imposing minimal loads on the inner valve assembly that could degrade the performance of the valve leaflets.

Abstract: A hydraulic screw tensioning device includes a tubular body, with a through opening and an annular cylinder chamber surrounding the through opening and a tubular piston movably supported in the tubular body and connectable to a screw to be tensioned. The tubular piston includes a stepped outer portion and divides the annular cylinder chamber into a first pressure chamber and a second pressure chamber. The second pressure chamber is closed by an annular end cap secured to the tubular body. The first pressure chamber is connectable to a pressure source for hydraulic fluid. The second pressure chamber is connectable to a pressure source for a compressible medium via a conduit connector mounted on the annular end cap. The conduit connector extends radially in relation to a geometric axis (A-A) of the tubular body. A damage protecting structure is provided to protect the conduit connector against accidental physical damage.

Abstract: Disclosed is a conveyor system including a first conveyor leading to an inspection point, the first conveyor including a diversion mechanism configured to divert an object based on failing to meet an inspection parameter. The system includes a second conveyor configured to transport a container configured to receive the object from the diversion mechanism. A control module is configured to co-register an image of the object captured at the inspection point with container ID data of the container.

Abstract: The present invention provides compounds of formula (I) compositions comprising such compounds; the use of such compounds in therapy; and methods of treating patients with such compounds; wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are as defined herein.

Abstract: A rebar tying system including a chassis with a central opening that passes from top to bottom of the chassis, a plurality of driven wheels coupled to the chassis and configured to propel the rebar tying system bidirectionally over a rebar mat, a plurality of foot members coupled to the chassis and configured to selectively move the rebar tying system in a lateral direction relative the bidirectional wheel propelled movement, and a rebar tying gun configured to be selectively positionable both horizontally and vertically in the central opening to perform rebar tying operations.

Abstract: The invention encompasses a rapid and safe preparation method of sperm nuclei, improved sperm nuclei and a method of using the improved sperm nuclei to calibrate a flow cytometer with higher accuracy.

Abstract: A restraint apparatus for securing a mobility device in a vehicle includes a base configured to being mounted to a floor of the vehicle, a support coupled to the base and extending upward therefrom, and a backing plate adjustably coupled to the support. The backing plate defines a channel to provide vertical adjustment of the backing plate with respect to the support. An upper support is pivotally coupled to the backing plate, and a claw assembly is coupled to the upper support. The claw assembly includes a claw member and a latching member, where the latching member is pivotally coupled to the claw member to enable pivotal movement between an unlatched position and a latched position. A control system operably controls the pivotal movement of the latching member between its latched position to its unlatched positions. In the unlatched position, the claw assembly provides an opening for receiving the device.

Abstract: Described herein is a computer implemented method. The method includes displaying, on a display, a scene timeline including a time-ordered sequence of scene previews, each scene preview corresponding to a scene of a video production and having a display width that provides a visual indication of a duration of that scene. The method further includes displaying a canvas including a first visual element that is associated with the first scene, and in response to detecting selection of the first visual element from the canvas, causing a first visual element timing indicator to be displayed. The first visual element timing indicator is aligned with the scene timeline based on a first visual element start time and a first visual element end time.

Abstract: Described herein is a computer implemented method, including accessing production data which defines first and second audio elements and displaying, on a display, a collapsed audio timeline including a first audio timing indicator corresponding to the first audio element and a second audio timing indicator corresponding to the second audio element. The first and second audio timing indicators have first and second indicator starts displayed at horizontal positions that correspond to first and second element start times, first and second indicator ends displayed at horizontal positions that correspond to first and second element end times, and first and second indicator display heights. The first and second audio timing indicators are both displayed on a first rank such that they vertically overlap, the second audio timing indicator is displayed in front of the first audio timing indicator, and the second indicator display height is less than the first indicator display height.

Abstract: A prosthetic heart valve can include an outer support assembly, an inner valve assembly, which define between them an annular space, and a pocket closure that bounds the annular space to form a pocket in which thrombus can be formed and retained. Alternatively, or additionally, the outer support assembly and the inner valve assembly can be coupled at the ventricle ends of the outer support assembly and the inner valve assembly, with the outer support assembly being relatively more compliant in hoop compression in a central, annulus portion than at the ventricle end, so that the prosthetic valve can seat securely in the annulus while imposing minimal loads on the inner valve assembly that could degrade the performance of the valve leaflets.

Abstract: A prosthetic heart valve can include an outer frame coupled to an inner frame such that the outer frame can be moved between a first position and a second position in which the outer frame is inverted relative to the inner frame. The inner frame and the outer frame define between them an annular space, and a pocket closure can bound the annular space to form a pocket in which thrombus can form and be retained. The pocket closure can include a stretchable pocket covering that can move from a first position in which the pocket covering has a first length when the outer frame is in the first position relative to the inner frame and a second position in which the pocket covering has a second length greater than the first length when the outer frame is in the second position relative to the inner frame.

Abstract: The present invention relates to systems and methods for intelligently optimizing supply chain is provided. In particular, the systems and methods provide the capability to configure supply chain systems so as to: balance between cost and service is optimised and profitability maximised; configure system parameters to respond to both current and future risks; ensure that variability is built into plans enabling maximised efficiency; and human error and bias are eliminated from the planning process such that pro-active rather than reactive behaviour becomes the norm.

Abstract: The present invention provides compounds of formula (I): Formula (I) compositions comprising such compounds; the use of such compounds in therapy; and methods of treating patients with such compounds; wherein A, Y, n, R1, R2A, R2B, R3 and *1 are as defined herein.

Abstract: The present invention provides compounds of formula (I) compositions comprising such compounds; the use of such compounds in therapy; and methods of treating patients with such compounds; wherein A, B, and, n, are as defined herein.

Abstract: Cell sorting methods that improve sorting efficiency and productivity by elevating sorting pressures and incorporate certain steps to help the cells better survive such elevated pressures. In the case of sperm, sorting the steps of standardizing sperm samples, staining sperm samples in a single step, calibrating a flow cytometer to place sperm in the leading edge of droplets, and changing a catch fluid distance may be incorporated individually, or in combination to help sperm better survive the sex sorting process.

Abstract: The present invention provides methods of monitoring and measuring tumor-associated free PSA (“fPSA”) with antibody polypeptides as an indication of androgen receptor signaling. In a particular embodiment, the methods may be used to assess the efficacy of anti-androgen and/or general anti-cancer treatments. The present invention also provides various methods and compositions relating to antibodies that are specific for tumor-associated or intratumoral fPSA. For example, the present invention provides compositions, including pharmaceutical compositions, comprising anti-fPSA antibodies, or fragments or characteristic portions thereof. The present invention further provides various therapeutic and/or diagnostic methods of using anti-fPSA antibodies and/or compositions.