Abstract: The invention encompasses a rapid and safe preparation method of sperm nuclei, improved sperm nuclei and a method of using the improved sperm nuclei to calibrate a flow cytometer with higher accuracy.

Abstract: In flow cytometry, particles (2) can be distinguished between populations (8) by combining n-dimensional parameter data, which may be derived from signal data from a particle, to mathematically achieve numerical results representative of an alteration (48). An alteration may include a rotational alteration, a scaled alteration, or perhaps even a translational alteration. Alterations may enhance separation of data points which may provide real-time classification (49) of signal data corresponding to individual particles into one of at least two populations.

Abstract: Systems and methods are provided for efficiently performing processing intensive operations, such as those involving large volumes of data, that enable accelerated processing time of these operations. In at least one embodiment, a system includes a graphics processor unit (GPU) including a memory and a plurality of cores. The plurality of cores perform a plurality of data analytics operations on a respectively allocated portion of a dataset, each of the plurality of cores using only the memory to store data input for each of the plurality of data analytics operations performed by the plurality of cores. The data storage for the plurality of data analytics operations performed by the plurality of cores is also provided solely by the memory.

Abstract: The present disclosure is directed to systems and methods for managing on-site communications of a machine with a latency-dependent application installed. The method includes, for example, (i) receiving geographical information associated with a work site; (ii) receiving historical communications information associated with the work site; (iii) analyzing the historical communications information and the geographical information; (iv) generating an instruction for implementing the latency-dependent application of the machine based on a latency requirement of the latency-dependent application; and (v) implementing the latency-dependent application of the machine based on the instruction. The historical communications information includes a communications event, a duration of the communications event, and a frequency of the communications event.

Abstract: Methods, apparatus, systems, and articles of manufacture are disclosed to determine total audience ratings. An example apparatus includes metrics generator circuitry to generate a first audience size for media accessed by first devices of a first media platform at a first level of aggregation, the first level of aggregation corresponding to the media accessed on a first television network and on a first website, generate a second audience size for the media accessed by the first devices of the first media platform at a second level of aggregation, the second level of aggregation corresponding to the media accessed on the first television network and accessed on the first website and a second website, comparator circuitry to compare the first audience size to the second audience size, adjustor circuitry to reduce the first audience size based on the second audience size, and audience determination circuitry to determine a total audience size.

Abstract: The present invention provides compounds of formula (I), compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, R12, R13, A, L, B, n, W, X, Y and Z are as defined herein.

Abstract: Methods, apparatus, systems and articles of manufacture to determine whether a smart device is in-tab are disclosed. An example apparatus includes memory; instructions in the apparatus; and processor circuitry to execute the instructions to: provide smart television data from a smart television as an input to a model to generate an output, the smart television data being included in population data from a population of smart televisions; determine a tab status of the smart television based on the output; in response to the tab status of the smart television being out-of-tab, remove the smart television data from the population data; and credit media based on the population data.

Abstract: Malicious threat detection through time-series graph analysis, in which a data analysis device receives a data file comprising multiple log data entries. The log data entries include parameters associated with a computer network event in a computing network. The data analysis device produces a graphical model of the computing network based on at least one parameter included in the log data. The data analysis device also identifies a parameter associated with a node of the computer network represented by the graphical model, and performs a time-series analysis on the parameter. The data analysis device further determines, based on the time-series analysis on the parameter, at least one of an anomalous event associated with the computing network or a malicious event associated with the computing network.

Abstract: Systems and methods are provided for efficiently performing processing intensive operations, such as those involving large volumes of data, that enable accelerated processing time of these operations. In at least one embodiment, a system includes a graphics processor unit (GPU) including a memory and a plurality of cores. The plurality of cores perform a plurality of data analytics operations on a respectively allocated portion of a dataset, each of the plurality of cores using only the memory to store data input for each of the plurality of data analytics operations performed by the plurality of cores. The data storage for the plurality of data analytics operations performed by the plurality of cores is also provided solely by the memory.

Abstract: An additive manufacturing system includes a build platform, a particulate dispenser assembly configured to dispense or remove particulate to or from the build platform, and a plurality of print heads each having at least one binder jet. The binder jets are configured to dispense at least one binder in varying densities onto the particulate in multiple locations to consolidate the particulate to form the component with a variable binder density throughout. The system also includes a plurality of arms extending at least partially across the build platform and supporting the print heads and at least one actuator assembly configured to rotate the print heads and/or the build platform about a rotation axis and move at least one of the print heads and the build platform in a build direction perpendicular to the build platform as part of a helical build process for the component.

Abstract: A grounding arrangement for a Voltage Source Converter (VSC) in a power transmission system is provided. The VSC comprises at least one converter branch (20) comprising at least one module (221-22N), each module comprising a plurality of serially connected sub-modules (241-248) that can be controllably switched to generate a controlled voltage across the module (221-22N) and each module including a first sub-module (241) at one end thereof and a last sub-module (248) at an opposite end thereof. Each sub-module (241-248) includes a first terminal (381), a second terminal (382), an energy storage element (30) and a switching arrangement (32, 34), wherein at least one of the first (381) or second terminals (382) is coupled to a terminal of the energy storage unit (30).

Abstract: The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B, W, X, Y and Z are as defined herein.

Abstract: Methods and systems for fabricating a component by consolidating a particulate include a build platform configured to receive a particulate, a particulate dispenser configured to deposit the particulate on the build platform, and at least one print head including at least one jet. The at least one print head is configured to dispense a binder through the at least one jet onto the particulate to consolidate at least a portion of the particulate and form a component. The methods and systems also include at least one actuator assembly configured to rotate at least one of the at least one print head and the build platform about a rotation axis extending through the build platform and move at least one of the at least one print head and the build platform in a build direction perpendicular to the build platform as part of a helical build process for the component.

Abstract: The present invention provides compounds of formula (I), compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, R12, R13, A, L, B, n, W, X, Y and Z are as defined herein.

Abstract: Methods, apparatus, systems and articles of manufacture to determine whether a smart device is in-tab are disclosed. An example apparatus includes a labelled data generator to identify a first smart television that corresponds to a first panelist by comparing first data from the first smart television to second data from the first panelist; and generate training data by labelling the first smart television as in-tab or out-of-tab based on the second data from the first panelist; and a model trainer to train a model using the training data, the model trainer to train the model to determine a tab status for a second smart television.

Abstract: An additive manufacturing system includes a control system communicatively coupled to a consolidation device and configured to control operation of the consolidation device. The control system is configured to generate a model of a component. The model includes a plurality of elements and at least one region of interest. The control system is also configured to apply a strain load to at least one element of the plurality of elements and generate a build characteristic contribution profile for at least one element of the plurality of elements. The build characteristic contribution profile represents an effect of the strain load applied to the at least one element on a build characteristic of at least one location within the at least one region of interest. The control system is further configured to adjust a build parameter for a location within the component relating to the at least one element of the plurality of elements based on the build characteristic contribution profile.

Abstract: The present invention provides a selection of compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B, W, X, Y and Z are as defined herein.

Abstract: Graph database analysis for network anomaly detection systems, in which a data analysis device receives multiple log data entries including parameters associated with a computer network event in a computing network. The data analysis device extracts one or more parameters in real-time and generates a network event graph based on at least one of a first graph metric or a second graph metric. The first and second graph metrics are based on the one or more extracted parameters. The data analysis device detects, based on queries performed on the network event graph, at least one of an anomalous event associated with the computing network or a malicious event associated with the computing network.

Abstract: A technique for adjusting the brightness values of images to be displayed on a stereoscopic head mounted display is provided herein. This technique improves the perceived dynamic range of the head mounted display by dynamically adjusting the pixel intensities (also known generally as “exposure”) of the images presented on the head mounted display based on a detected gaze direction. The head mounted display includes an eye tracker that is able to sense the gaze directions of the eyes. The eye tracker, head mounted display, or a processor of a computer system receives this information, determines an intersection point of the eye gaze and a screen within the head mounted display and identifies a gaze area around this intersection point. Using this gaze area, the processing system adjusts the pixel intensities of an image displayed on the screen based on the intensities of the pixels within the gaze area.