Abstract: Techniques for mobile network geolocation are disclosed. In one particular exemplary embodiment, the techniques may be realized as a system for mobile network geolocation. The system may comprise one or more processors communicatively coupled to a mobile communications network. The one or more processors may be configured to determine that a mobile device is on a travel path. The one or more processors may also be configured to determine one or more candidate locations of the mobile device based on data associated with the travel path. The one or more processors may further be configured to determine at least one candidate route associated with the mobile device along the travel path comprised from one or more candidate locations.

Abstract: It is an object of the instant invention to provide a method for the rapid evaluation of novel sugar modifications to be used in siRNA synthesis including the rapid evaluation of chemical modification patterns within the siRNA to effectuate increased stability and ultimately increased efficacy of a siRNA therapeutic. It is a further object of the instant invention to provide novel nucleosides useful for siRNA therapy.

Abstract: Techniques for mobile network geolocation are disclosed. In one particular exemplary embodiment, the techniques may be realized as a system for mobile network geolocation. The system may comprise one or more processors communicatively coupled to a mobile communications network. The one or more processors may be configured to determine that a mobile device is on a travel path. The one or more processors may also be configured to determine one or more candidate locations of the mobile device based on data associated with the travel path. The one or more processors may further be configured to determine at least one candidate route associated with the mobile device along the travel path comprised from one or more candidate locations.

Abstract: Techniques for dynamic network optimization using geolocation and network modeling are disclosed. In one particular exemplary embodiment, the techniques may be realized as a system for network optimization. The system may comprise a data collection system configured to collect geolocated subscriber records from a plurality of mobile devices. The system may also comprise a SON optimization system communicatively coupled to the data collection system via a network. The SON optimization system may comprise at least one pre-processor configured to receive and process geolocated subscriber records from the data collection system. The SON optimization system may further comprise a network simulator configured to perform network simulation analysis based on the processed geolocated subscriber records, and provide a new network configuration based on the network simulation analysis, wherein the new network configuration is estimated to improve network performance.

Abstract: Techniques for dynamic network optimization using geolocation and network modeling are disclosed. In one particular exemplary embodiment, the techniques may be realized as a system for improving performance of a mobile communications network. The system may comprise one or more processors communicatively coupled to a mobile communications network. The one or more processors may be configured to determine allowable changes within a network and rank a cell or parameter based on a priority rule. The one or more processors may be further be configured to generate a plurality of network configurations and evaluate strength of the plurality of network configurations. The one or more processors may also be configured to output a set of network configurations that is strongest among the plurality of network configurations.

Abstract: Techniques for dynamic network optimization using geolocation and network modeling are disclosed. In one particular exemplary embodiment, the techniques may be realized as a system for network optimization. The system may comprise a data collection system configured to collect geolocated subscriber records from a plurality of mobile devices. The system may also comprise a SON optimization system communicatively coupled to the data collection system via a network. The SON optimization system may comprise at least one pre-processor configured to receive and process geolocated subscriber records from the data collection system. The SON optimization system may further comprise a network simulator configured to perform network simulation analysis based on the processed geolocated subscriber records, and provide a new network configuration based on the network simulation analysis, wherein the new network configuration is estimated to improve network performance.

Abstract: It is an object of the instant invention to provide a method for the rapid evaluation of novel sugar modifications to be used in siRNA synthesis including the rapid evaluation of chemical modification patterns within the siRNA to effectuate increased stability and ultimately increased efficacy of a siRNA therapeutic. It is a further object of the instant invention to provide novel nucleosides useful for siRNA therapy.

Abstract: It is an object of the instant invention to provide a method for the rapid evaluation of novel sugar modifications to be used in siRNA synthesis including the rapid evaluation of chemical modification patterns within the siRNA to effectuate increased stability and ultimately increased efficacy of a siRNA therapeutic. It is a further object of the instant invention to provide novel nucleosides useful for siRNA therapy.

Abstract: System, methods, and computer-readable media for determining allowed reimbursement amounts for one or more healthcare services rendered by a healthcare provider to a patient are disclosed. The allowed reimbursement amount may be determined in accordance with reimbursement model parameter(s) and/or reimbursement rule(s) associated with a reimbursement model.

Abstract: An index advice record engine generates and stores index advice records. An index advice policy mechanism allows a user to define an index advice policy that specifies criteria for autonomic index creation, modification and deletion. An autonomic index mechanism reads the index advice records, compares this information with the criteria in the user-defined index advice policies, and determines whether an index should be created, modified or deleted based on the information in the index advice records and the index advice policies. By automating the process of creating, modifying and deleting indexes according to user-defined policies, the preferred embodiments alleviate human users from most of the work of manually creating, modifying and deleting indexes.

Abstract: An index advice record engine generates and stores index advice records. An index advice policy mechanism allows a user to define an index advice policy that specifies criteria for autonomic index creation. An autonomic index creation mechanism reads the index advice records, compares this information with the criteria in the user-defined index advice policies, and determines whether an index should be created based on the information in the index advice records and the index advice policies. By automating the process of creating indexes according to user-defined policies, the preferred embodiments alleviate human users from most of the work of manually creating indexes.

Abstract: Embodiments of the invention provide a method, article of manufacture, and an apparatus used to provide an interface driven by database tables. The method includes receiving a query identifier associated with a database query. The query is executed to generate a set of query results, and a set of actions associated with the set of query result is also identified. The set of query results and the set of actions are provided to a client component of the database-driven interface.

Abstract: An index advice record engine generates and stores index advice records. An index advice policy mechanism allows a user to define an index advice policy that specifies criteria for autonomic index creation, modification and deletion. An autonomic index mechanism reads the index advice records, compares this information with the criteria in the user-defined index advice policies, and determines whether an index should be created, modified or deleted based on the information in the index advice records and the index advice policies. By automating the process of creating, modifying and deleting indexes according to user-defined policies, the preferred embodiments alleviate human users from most of the work of manually creating, modifying and deleting indexes.

Abstract: A database query optimizer includes an access plan storage mechanism that stores execution detail corresponding to a query statement in an access plan cache. By storing execution detail in the access plan cache along with the query statement, the execution detail is available when needed to debug database problems, even after a problem occurs. The execution detail stored in the access plan cache may be mined and analyzed after-the-fact, producing a very powerful tool for debugging database problems. Snapshots of the execution detail may also be created by a user. In addition, the user may setup autonomic snapshots and comparisons so that a user may be alerted from a degradation in database performance between two snapshots.

Abstract: A mass spectrometer having a matrix-assisted laser desorption ionization (MALDI) source which operates at ambient pressure is disclosed.

Abstract: It is an object of the instant invention to provide a method for the rapid evaluation of novel sugar modifications to be used in siRNA synthesis including the rapid evaluation of chemical modification patterns within the siRNA to effectuate increased stability and ultimately increased efficacy of a siRNA therapeutic. It is a further object of the instant invention to provide novel nucleosides useful for siRNA therapy.

Abstract: An index advice record engine generates and stores index advice records. An index advice policy mechanism allows a user to define an index advice policy that specifies criteria for autonomic index creation, modification and deletion. An autonomic index mechanism reads the index advice records, compares this information with the criteria in the user-defined index advice policies, and determines whether an index should be created, modified or deleted based on the information in the index advice records and the index advice policies. By automating the process of creating, modifying and deleting indexes according to user-defined policies, the preferred embodiments alleviate human users from most of the work of manually creating, modifying and deleting indexes.

Abstract: A database graphical comparison tool allows comparing database items that include multiple database statements and graphically displaying the comparison results in a ranked list of database statements. The graphical comparison tool includes a graphical user interface that allows a user to easily configure the tool for both manual and automatic (or scheduled) comparisons. In addition, the user may specify one or more actions that may be autonomically performed when the comparison of database items meets predefined criteria. Database items that may be compared using the database graphical comparison tool include optimizer monitors and plan cache snapshots.

Abstract: A database management system maintains a record of queries which can be executed against the database. For a given auxiliary database structure, an advisory function automatically reviews the query record and identifies those queries which might execute with greater efficiency using the auxiliary database structure, presenting analytical information to the user. Preferably, the auxiliary database structure is an index, and the information is used for determining whether to include the index in the database definition. Preferably, a query optimizer records potentially useful indexes when considering multiple alternative database optimizations, and this information is later retrieved to identify queries which would benefit from an index.

Abstract: Methods and compositions are disclosed for the reduction of immune responses to an exogenous allergen. The reduction is obtained by pre-treatment or pre-conditioning, without injection, of a subject with the allergen so as to reduce immune responses in the subject upon additional exposure to the allergen. The invention is advantageously used in a variety of contexts, including seasonal allergies wherein pre-treatment or pre-conditioning is performed before the onset of the seasonal allergy.