Abstract: The invention relates to a planetary gearbox in a gas turbine engine wherein a plurality of planetary gears are each mounted on a planetary gear bearing journal by a slide bearing, characterized in that a bushing is arranged in an inner bore of at least one planetary gear, which bushing spatially separates the sliding surface of the slide bearing from the inner bore of the planetary gear and the bushing is designed as a replacement part, in particular as a sacrificial part. The invention also relates to a gas turbine engine.

Abstract: A gear wheel of a transmission, in particular of a transmission of a gas turbine engine is described, which is designed with a groove which extends in the circumferential direction on the outer periphery of a base body of the gear wheel and in which fibers running at least in the circumferential direction are arranged. The fibers surround the base body in the circumferential direction, wherein the fibers at least partially support the operating loads on the gear wheel only on a breakage of the base body.

Abstract: Methods for safe and effective treatment of inflammatory lesions of rosacea in a subject are described. The methods involve once daily topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. It has been demonstrated that once daily topical treatment with ivermectin is significantly superior than twice-daily topical treatment with metronidazole in reducing inflammatory lesion counts.

Abstract: A gas turbine engine for an aircraft that includes an engine core, a fan, and a planetary gearbox. The planetary gearbox includes a sun gear, a plurality of planetary gears, a ring gear, a plurality of planetary pins, wherein respectively one planetary pin is arranged in a planetary gear, and an axially frontal support plate and an axially rear support plate, wherein the planetary pins are arranged in openings of the axially frontal support plate and of the axially rear support plate, and are connected to the support plates. At least one of the support plates has an axially protruding first centering collar that engages around the opening for the planetary pin, and that a second centering collar that is connected to the planetary pin or is formed in one piece with the same, engaging around the first centering collar radially outside in a form-fit manner. A planetary gearbox and an attachment arrangement.

Abstract: Methods for safe and effective treatment of inflammatory lesions of rosacea in a subject are described. The methods involve once daily topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. It has been demonstrated that once daily topical treatment with ivermectin is significantly superior than twice-daily topical treatment with metronidazole in reducing inflammatory lesion counts.

Abstract: Disclosed herein are methods for selectively treating acne vulgaris of the face and/or trunk in a subject, pharmaceutical compositions for use in the treatment of acne vulgaris of the face and/or trunk in a subject, uses of trifarotene or an equivalent thereof in the manufacture of a medicament for the treatment of acne vulgaris of the face and/or trunk in a subject.

Abstract: Methods for safe and effective treatment of inflammatory lesions of rosacea in a subject are described. The methods involve once daily topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. It has been demonstrated that once daily topical treatment with ivermectin is significantly superior than twice-daily topical treatment with metronidazole in reducing inflammatory lesion counts.

Abstract: A gas turbine engine for an aircraft that includes an engine core, a fan, and a planetary gearbox. The planetary gearbox includes a sun gear, a plurality of planetary gears, a ring gear, a plurality of planetary pins, wherein respectively one planetary pin is arranged in a planetary gear, and an axially frontal support plate and an axially rear support plate, wherein the planetary pins are arranged in openings of the axially frontal support plate and of the axially rear support plate, and are connected to the support plates. At least one of the support plates has an axially protruding first centering collar that engages around the opening for the planetary pin, and that a second centering collar that is connected to the planetary pin or is formed in one piece with the same, engaging around the first centering collar radially outside in a form-fit manner. A planetary gearbox and an attachment arrangement.

Abstract: Methods and compositions for safe and effective treatment of papulopustular rosacea in a subject are described. The methods involve topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. Treatment with ivermectin represents an innovative therapy that is more robust and effective than the conventional treatments.

Abstract: Methods and compositions for safe and effective treatment of papulopustular rosacea in a subject are described. The methods involve topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. Treatment with ivermectin represents an innovative therapy that is more robust and effective than the conventional treatments.

Abstract: Methods and compositions for safe and effective treatment of papulopustular rosacea in a subject are described. The methods involve topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. Treatment with ivermectin represents an innovative therapy that is more robust and effective than the conventional treatments.

Abstract: Methods for safe and effective treatment of inflammatory lesions of rosacea in a subject are described. The methods involve once daily topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. It has been demonstrated that once daily topical treatment with ivermectin is significantly superior than twice-daily topical treatment with metronidazole in reducing inflammatory lesion counts.

Abstract: Dermatological disorders having an inflammatory or proliferative component are treated with pharmaceutical compositions containing on the order of 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthanoic acid (adapalene) or salt thereof, formulated into pharmaceutically acceptable media therefor, advantageously topically applicable gels, creams or lotions.

Abstract: Dermatological disorders having an inflammatory or proliferative component are treated with pharmaceutical compositions containing on the order of 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthanoic acid (adapalene) or salt thereof, formulated into pharmaceutically acceptable media therefor, advantageously topically applicable gels, creams or lotions.

Abstract: A garment includes a connected front and back panels forming a cavity for an upper body of a subject. Each of a pair of sleeves is connected to at least one of the front or back panel and is in communication with the cavity. A collar is configured to surround a neck of the subject. Each of a pair of shoulder straps is connected at one end to the collar and at an opposing end to at least one of the front or back panels or a sleeve. A first opening is formed by at least the straps, a top edge of the front panel, and the collar to expose a top portion of the subject's chest. A second opening is formed by at least the straps, a top edge of the back panel, and the collar to expose a top portion of the subject's back.

Abstract: Dermatological disorders having an inflammatory or proliferative component are treated with pharmaceutical compositions containing on the order of 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthanoic acid (adapalene) or salt thereof, formulated into pharmaceutically acceptable media therefor, advantageously topically applicable gels, creams or lotions.

Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.

Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.

Abstract: Methods and products for treating or preventing erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical aqueous gel composition comprising about 0.01% to about 10% by weight of at least one ?-adrenergic receptor agonist and a pharmaceutically acceptable carrier.

Abstract: Methods and compositions for safe and effective treatment of papulopustular rosacea in a subject are described. The methods involve topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. Treatment with ivermectin represents an innovative therapy that is more robust and effective than the conventional treatments.