Patents by Inventor Michael Graeber

Michael Graeber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PREVENTING OR TREATING SKIN TUMOR
    Publication number: 20130251649
    Abstract: Methods, compositions and products for preventing skin tumor formation or inhibiting the development of an existing skin tumor in a subject are described. The methods involve administering to the subject a composition containing an ? adrenergic receptor agonist, such as brimonidine.
    Type: Application
    Filed: June 29, 2011
    Publication date: September 26, 2013
    Applicant: GALDERMA RESEARCH & DEVELOPMENT SNC
    Inventors: Guy Bouvier, Matthew James Leoni, Michael Graeber
  • METHOD FOR PREVENTING OR TREATING SKIN TUMOR
    Publication number: 20130243705
    Abstract: Methods, compositions and products for preventing skin tumor formation or inhibiting development of an existing skin tumor in a subject are described. The methods involve administering to the subject a composition containing an ?2 adrenergic receptor agonist, such brimonidine.
    Type: Application
    Filed: June 29, 2011
    Publication date: September 19, 2013
    Applicant: GALDERMA RESEARCH & DEVELOPMENT SNC
    Inventors: Guy Bouvier, Matthew James Leoni, Michael Graeber
  • Methods and compositions for safe and effective treatment of erythema
    Patent number: 8513249
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.4% to about 0.6% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: August 20, 2013
    Assignee: Galderma Laboratories, L.P.
    Inventors: Michael Graeber, Christian Loesche, Philip Freidenreich, Yin-Sang Liu, Matthew J. Leoni
  • Methods and compositions for safe and effective treatment of erythema
    Patent number: 8513247
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.4% to about 0.6% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: August 20, 2013
    Assignee: Galderma Laboratories, L.P.
    Inventors: Michael Graeber, Christian Loesche, Philip Freidenreich, Yin-Sang Liu, Matthew J. Leoni
  • Methods and compositions for treating or preventing erythema
    Patent number: 8410102
    Abstract: Methods and products for treating or preventing erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical aqueous gel composition comprising about 0.01% to about 10% by weight of at least one ?-adrenergic receptor agonist and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: April 2, 2013
    Assignee: Galderma Laboratories Inc.
    Inventors: Michael Graeber, Christian Loesche, Philip Freidenreich, Jack A. Dejovin, Isabelle Jean Dejovin, Yin-Sang Liu, Matthew James Leoni
  • METHODS AND COMPOSITIONS FOR SAFE AND EFFECTIVE TREATMENT OF ERYTHEMA
    Publication number: 20130071489
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: March 25, 2011
    Publication date: March 21, 2013
    Applicant: GALDERMA RESEARCH & DEVELOPMENT SNC
    Inventors: Michael Graeber, Christian Loesche, Philip Freidenreich, Yin Liu, Matthew James Leoni
  • METHODS AND COMPOSITIONS FOR SAFE AND EFFECTIVE TREATMENT OF TELANGIECTASIA
    Publication number: 20130059857
    Abstract: Improved methods and compositions for safe and effective treatment of telangiectasia or a symptom associated with telangiectasia in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: March 25, 2011
    Publication date: March 7, 2013
    Applicant: GALDERMA RESEARCH & DEVELOPMENT SNC
    Inventors: Michael Graeber, Christian Loesche, Philip Freidenreich, Yin Liu, Matthew James Leoni
  • ADMINISTRATION OF 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID FOR THE TREATMENT OF DERMATOLOGICAL DISORDERS
    Publication number: 20120231062
    Abstract: Dermatological disorders having an inflammatory or proliferative component are treated with pharmaceutical compositions containing on the order of 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid (adapalene) or salt thereof, formulated into pharmaceutically acceptable media therefor, advantageously topically applicable gels, creams or lotions.
    Type: Application
    Filed: May 18, 2012
    Publication date: September 13, 2012
    Inventors: Michael GRAEBER, Janusz Czernielewski
  • METHODS AND COMPOSITIONS FOR SAFE AND EFFECTIVE TREATMENT OF ERYTHEMA
    Publication number: 20120214816
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.4% to about 0.6% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: April 26, 2012
    Publication date: August 23, 2012
    Applicant: Galdema R&D Inc.
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Yin-Sang LIU, Matthew J. LEONI
  • COMBINATION TREATMENT FOR ROSACEA
    Publication number: 20120082625
    Abstract: The invention relates to a method of treating erythema and/or telangiectasia associated with rosacea in a patient in need thereof by topically administering an effective amount of a combination of brimonidine or a pharmaceutically acceptable salt thereof and oxymetazoline or a pharmaceutically acceptable salt thereof to the site of erythema and/or telangiectasia on the skin of the patient. The invention further relates to topical compositions including the combination of compounds and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: September 14, 2011
    Publication date: April 5, 2012
    Inventors: Michael Graeber, Matthew James Leoni, Nathalie Wagner
  • COMBINATION TREATMENT FOR DERMATOLOGICAL CONDITIONS
    Publication number: 20120076738
    Abstract: The invention relates to a method of treating dermatological conditions or symptoms associated therewith in a patient in need thereof by topically administering an effective amount of a combination of brimonidine or a pharmaceutically acceptable salt thereof and oxymetazoline or a pharmaceutically acceptable salt thereof to the affected area of skin on the patient. The invention further relates to topical compositions including the combination of compounds and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: September 14, 2011
    Publication date: March 29, 2012
    Inventors: Michael Graeber, Matthew James Leoni, Nathalie Wagner
  • METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING ERYTHEMA
    Publication number: 20110288096
    Abstract: Methods and products for treating or preventing erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical aqueous gel composition comprising about 0.01% to about 10% by weight of at least one ?-adrenergic receptor agonist and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: March 25, 2011
    Publication date: November 24, 2011
    Applicant: GALDERMA LABORATORIES INC.
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Jack A. DEJOVIN, Isabelle Jean DEJOVIN, Yin-Sang LIU, Matthew J. LEONI
  • METHODS AND COMPOSITIONS FOR SAFE AND EFFECTIVE TREATMENT OF ERYTHEMA
    Publication number: 20110286944
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.4% to about 0.6% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: March 25, 2011
    Publication date: November 24, 2011
    Applicant: GALDERMA R&D INC.
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Yin-Sang LIU, Matthew J. LEONI
  • Methods of Treating or Preventing Acute Erythema
    Publication number: 20110224216
    Abstract: A method of treating or preventing acute erythema in a human in need thereof by topical administration of an effective amount of an alpha adrenergic receptor agonist or pharmaceutically acceptable salt thereof is claimed. The preferred alpha adrenergic receptor agonist is brimonidine. A method of preventing secondary inflammation caused by acute erythema by topical administration of an effective amount of an alpha adrenergic receptor agonist or a pharmaceutically acceptable salt thereof is also claimed.
    Type: Application
    Filed: October 19, 2010
    Publication date: September 15, 2011
    Applicant: GALDERMA LABORATORIES INC.
    Inventors: Philippe Andres, Christian Loesche, Michael Graeber
  • ADMINISTRATION OF 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID FOR THE TREATMENT OF DERMATOLOGICAL DISORDERS
    Publication number: 20110130461
    Abstract: Dermatological disorders having an inflammatory or proliferative component are treated with pharmaceutical compositions containing on the order of 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthanoic acid (adapalene) or salt thereof, formulated into pharmaceutically acceptable media therefor, advantageously topically applicable gels, creams or lotions.
    Type: Application
    Filed: February 10, 2011
    Publication date: June 2, 2011
    Applicant: Galderma Research & Development
    Inventors: Michael GRAEBER, Janusz Czernielewski
  • METHOD FOR THE TREATMENT OF ACNE USING COMPOSITIONS COMPRISING 0.3% BY WEIGHT OF 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID
    Publication number: 20110070176
    Abstract: Dermatological disorders having an inflammatory or proliferative component, notably common acne, are treated with topically applicable pharmaceutical compositions containing about 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthanoic acid (adapalene) or salt thereof, formulated into pharmaceutically acceptable media therefor, advantageously formulated into topically applicable gels, preferably aqueous gels, creams, lotions or solutions.
    Type: Application
    Filed: December 1, 2010
    Publication date: March 24, 2011
    Applicant: Galderma Research & Development
    Inventors: Michael GRAEBER, Janusz Czernielewski
  • ADMINISTRATION OF 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID FOR THE TREATMENT OF DERMATOLOGICAL DISORDERS
    Publication number: 20110027204
    Abstract: Dermatological disorders having an inflammatory or proliferative component are treated with pharmaceutical compositions containing on the order of 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthanoic acid (adapalene) or salt thereof, formulated into pharmaceutically acceptable media therefor, advantageously topically applicable gels, creams or lotions.
    Type: Application
    Filed: October 12, 2010
    Publication date: February 3, 2011
    Applicant: Galderma Research & Development
    Inventors: Michael . Graeber, Janusz Czernielewski
  • ADMINISTRATION OF 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID FOR THE TREATMENT OF DERMATOLOGICAL DISORDERS
    Publication number: 20110027367
    Abstract: Dermatological disorders having an inflammatory or proliferative component are treated with pharmaceutical compositions containing on the order of 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthanoic acid (adapalene) or salt thereof, formulated into pharmaceutically acceptable media therefor, advantageously topically applicable gels, creams or lotions.
    Type: Application
    Filed: October 12, 2010
    Publication date: February 3, 2011
    Applicant: GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
    Inventors: Michael Graeber, Janusz Czernielewski
  • Method for the treatment of acne using compositions comprising 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid
    Patent number: 7868044
    Abstract: Dermatological disorders having an inflammatory or proliferative component, notably common acne, are treated with topically applicable pharmaceutical compositions containing about 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthanoic acid (adapalene) or salt thereof, formulated into pharmaceutically acceptable media therefor, advantageously formulated into topically applicable gels, preferably aqueous gels, creams, lotions or solutions.
    Type: Grant
    Filed: May 3, 2010
    Date of Patent: January 11, 2011
    Assignee: Galderma Research & Development
    Inventors: Michael Graeber, Janusz Czernielewski
  • Administration of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid for the treatment of dermatological disorders
    Patent number: 7838558
    Abstract: Dermatological disorders having an inflammatory or proliferative component are treated with pharmaceutical compositions containing on the order of 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthanoic acid (adapalene) or salt thereof, formulated into pharmaceutically acceptable media therefor, advantageously topically applicable gels, creams or lotions.
    Type: Grant
    Filed: April 15, 2008
    Date of Patent: November 23, 2010
    Assignee: Galderma Research & Development S.N.C.
    Inventors: Michael Graeber, Janusz Czernielewski